Analysis of Turnover and Translation Regulatory RNA-Binding Protein Expression through Binding to Cognate mRNAs

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Molecular and Cellular Biology

• Publication date

  2007-07-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.00500-07PMID 17620417PMCID PMC2099612
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphorylation of HuR by Chk2 regulates SIRT1 expression.

  2007cited by this paper
• Hu Proteins Regulate Polyadenylation by Blocking Sites Containing U-rich Sequences*

  2007cited by this paper
• Translational Control of Cytochrome c by RNA-Binding Proteins TIA-1 and HuR

  2006cited by this paper
• Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells

  2006cited by this paper
• The Drosophila Heterogeneous Nuclear Ribonucleoprotein M Protein, HRP59, Regulates Alternative Splicing and Controls the Production of Its Own mRNA*

  2006cited by this paper
• Translational Repression by RNA-Binding Protein TIAR

  2006cited by this paper
• Control of translation and mRNA degradation by miRNAs and siRNAs.

  2006cited by this paper
• Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.

  2006cited by this paper
• Relief of microRNA-mediated translational repression in human cells subjected to stress.

  2006cited by this paper
• Upf1/Upf2 Regulation of 3′ Untranslated Region Splice Variants of AUF1 Links Nonsense-Mediated and A+U-Rich Element-Mediated mRNA Decay

  2006cited by this paper
• MicroRNA Modulation of RNA-Binding Protein Regulatory Elements

  2006cited by this paper
• Antiapoptotic function of RNA‐binding protein HuR effected through prothymosin α

  2005cited by this paper
• The Xenopus ELAV Protein ElrB Represses Vg1 mRNA Translation during Oogenesis

  2005cited by this paper
• Identification and Functional Outcome of mRNAs Associated with RNA-Binding Protein TIA-1

  2005cited by this paper
• Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins

  2005cited by this paper
• Involvement of microRNA in AU-rich element-mediated mRNA instability.

  2005cited by this paper
• Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

  2005cited by this paper
• HuR as a negative posttranscriptional modulator in inflammation.

  2005cited by this paper
• p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.

  2005cited by this paper
• Inflammation in atherosclerosis: new opportunities for drug discovery.

  2005cited by this paper
• The ELAV RNA-stability factor HuR binds the 5′-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation

  2005influential reference
• From Birth to Death: The Complex Lives of Eukaryotic mRNAs

  2005cited by this paper
• Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay.

  2004cited by this paper
• Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

  2004cited by this paper
• The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself*

  2004cited by this paper
• Identification of a target RNA motif for RNA-binding protein HuR.

  2004cited by this paper
• The KH-Domain Protein αCP Has a Direct Role in mRNA Stabilization Independent of Its Cognate Binding Site

  2003cited by this paper
• Regulation of A + U-rich Element-directed mRNA Turnover Involving Reversible Phosphorylation of AUF1*

  2003cited by this paper
• Regulation of mRNA translation by 5'- and 3'-UTR-binding factors.

  2003cited by this paper
• Phosphorylation of p40AUF1 Regulates Binding to A + U-rich mRNA-destabilizing Elements and Protein-induced Changes in Ribonucleoprotein Structure*

  2003cited by this paper
• RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

  2003cited by this paper
• ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

  2002influential reference
• Nuclear export of NF90 is required for interleukin-2 mRNA stabilization.

  2002cited by this paper
• Lipopolysaccharide-induced Methylation of HuR, an mRNA-stabilizing Protein, by CARM1*

  2002cited by this paper
• Novel Binding of HuR and Poly(C)-binding Protein to a Conserved UC-rich Motif within the 3′-Untranslated Region of the Androgen Receptor Messenger RNA*

  2002cited by this paper
• Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation

  2002cited by this paper
• Stressful initiations.

  2002cited by this paper
• Functional cloning of BRF1, a regulator of ARE‐dependent mRNA turnover

  2002cited by this paper
• AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.

  2001cited by this paper
• TIA-1 and TIAR Activate Splicing of Alternative Exons with Weak 5′ Splice Sites followed by a U-rich Stretch on Their Own Pre-mRNAs*

  2001cited by this paper
• Molecular mechanisms of gene expression regulation by the apoptosis-promoting protein TIA-1

  2001cited by this paper
• HuR and mRNA stability

  2001cited by this paper
• The double lives of shuttling mRNA binding proteins.

  2000cited by this paper
• Down-Regulation of Cyclin D1 Expression by Prostaglandin A2 Is Mediated by Enhanced Cyclin D1 mRNA Turnover

  2000cited by this paper
• RNA-protein interactions in the control of stability and localization of messenger RNA (review).

  2000cited by this paper
• Nuclear targeting determinants of the far upstream element binding protein, a c-myc transcription factor.

  2000cited by this paper
• Regulation of AUF1 Expression via Conserved Alternatively Spliced Elements in the 3′ Untranslated Region

  1999cited by this paper
• Identification of TIAR as a Protein Binding to the Translational Regulatory AU-rich Element of Tumor Necrosis Factor α mRNA*

  1999cited by this paper
• Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

  1999cited by this paper
• Why is Hu where? Shuttling of early-response-gene messenger RNA subsets.

  1999cited by this paper
• Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR.

  1999cited by this paper
• Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element.

  1999cited by this paper
• ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells.

  1999cited by this paper
• Molecular cloning and characterization of a translational inhibitory protein that binds to coding sequences of human acid beta-glucosidase and other mRNAs.

  1999cited by this paper
• Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

  1998cited by this paper
• HNS, a nuclear-cytoplasmic shuttling sequence in HuR.

  1998cited by this paper
• Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

  1998cited by this paper
• A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.

  1997influential reference
• Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

  1997cited by this paper
• Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression.

  1997cited by this paper
• Individual RNA Recognition Motifs of TIA-1 and TIAR Have Different RNA Binding Specificities (*)

  1996cited by this paper
• AU-rich elements: characterization and importance in mRNA degradation.

  1995cited by this paper
• Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro(*)

  1995cited by this paper
• Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.

  1994cited by this paper
• Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

  1993cited by this paper
• Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.

  1991cited by this paper

• The RNA helicase DDX53 (CAGE) contributes to RNA metabolism in a human germ cell model

  2026cites this paper
• Interplay of microRNA-20a and HuR in the regulation of beclin1 during Withaferin-A mediated impaired autophagy in Breast Cancer cell-line, MCF-7

  2026cites this paper
• Multi-omic screening identifies RBMXL3 as a primate-specific RNA-binding protein and candidate regulator of RNA metabolism in human spermatogenesis

  2025cites this paper
• Structural, biological, and biomedical implications of mRNA interactions with the master regulator HuR

  2025cites this paper
• Multifaceted Human Antigen R (HuR): A Key Player in Liver Metabolism and MASLD

  2025cites this paper
• Function of epigenetic modifications in wound healing and potential therapies (Review).

  2025cites this paper
• The RNA-Binding Protein KSRP Is a Negative Regulator of Innate Immunity

  2025cites this paper
• RNA-protein interaction prediction without high-throughput data: An overview and benchmark of in silico tools

  2024cites this paper
• LncRNAs as nodes for the cross-talk between autophagy and Wnt signaling in pancreatic cancer drug resistance

  2024cites this paper
• Alternative splicing and related RNA binding proteins in human health and disease

  2024cites this paper
• Copy number amplification-induced overexpression of lncRNA LOC101927668 facilitates colorectal cancer progression by recruiting hnRNPD to disrupt RBM47/p53/p21 signaling

  2024cites this paper
• Cup is essential for oskar mRNA translational repression during early Drosophila oogenesis

  2023cites this paper
• RNA-binding proteins in metabolic-associated fatty liver disease (MAFLD): From mechanism to therapy.

  2023cites this paper
• The flavagline FL3 interferes with the association of Annexin A2 with the eIF4F initiation complex and transiently stimulates the translation of annexin A2 mRNA

  2023cites this paper
• RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts

  2023cites this paper
• Advances in the study of RNA-binding proteins in diabetic complications

  2022cites this paper
• The Role of KH-Type Splicing Regulatory Protein (KSRP) for Immune Functions and Tumorigenesis

  2022cites this paper
• Heterogeneous ribonucleoprotein D selectively regulates the expression of genes in the immune system

  2022cites this paper
• The landscape of aging

  2022cites this paper
• Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors

  2022cites this paper
• Pin1 and Alzheimer's Disease.

  2022cites this paper
• Keeping development on time: Insights into post‐transcriptional mechanisms driving oscillatory gene expression during vertebrate segmentation

  2022cites this paper
• T-Cell Intracellular Antigen 1-Like Protein in Physiology and Pathology

  2022cites this paper
• RNA regulation of inflammatory responses in glia and its potential as a therapeutic target in central nervous system disorders

  2022cites this paper
• Cell‐intrinsic mechanisms to restrain inflammatory responses in T lymphocytes

  2021cites this paper
• SRI‐42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide‐induced neuroinflammation

  2021cites this paper
• Functional characterization of the TTF complex and its role in neurodevelopmental disorders

  2021cites this paper
• AUF1 gene transfer increases exercise performance and improves skeletal muscle deficit in adult mice

  2021cites this paper
• HuR-targeted agents: an insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models.

  2021cites this paper
• OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation

  2021cites this paper
• Role of Viral Ribonucleoproteins in Human Papillomavirus Type 16 Gene Expression

  2020cites this paper
• p53 regulates its own expression by an intrinsic exoribonuclease activity through AU-rich elements

  2020cites this paper
• The RNA binding protein SRSF1 is a master switch of gene expression and regulation in the immune system.

  2020cites this paper
• Characterization of miR-574-5p decoy to CUGBP1 in human lung cancer cells using a mass spectrometry proteomics approach

  2020cites this paper
• mRNA Post-Transcriptional Regulation by AU-Rich Element-Binding Proteins in Liver Inflammation and Cancer

  2020cites this paper
• The functional interplay of lncRNA EGOT and HuR regulates hypoxia‐induced autophagy in renal tubular cells

  2020cites this paper
• Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA

  2020cites this paper
• RNA-binding proteins: The next step in translating skeletal muscle adaptations?

  2019cites this paper
• Auto-regulatory feedback by RNA-binding proteins

  2019cites this paper
• Mécanismes modulant la stabilité de l’ARNm alphaENaC des cellules épithéliales alvéolaires dans un environnement inflammatoire

  2019cites this paper
• NF90 regulation of immune factor expression in response to malaria antigens

  2019cites this paper
• MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans

  2019cites this paper
• The RNA Binding Protein HuR: A Promising Drug Target for Anticancer Therapy.

  2019cites this paper
• Recent Advances in Machine Learning Based Prediction of RNA-protein Interactions.

  2019cites this paper
• NMR Solution Structure of MINA-1(254-334)

  2019cites this paper
• The 3'UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization.

  2019cites this paper
• Two ways of escaping from oxidative RNA damage: Selective degradation and cell death.

  2019cites this paper
• Innate immune memory in fibroblasts

  2018cites this paper
• Deciphering human ribonucleoprotein regulatory networks

  2018cites this paper
• Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

  2018cites this paper
• Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance

  2018cites this paper
• Contrôle traductionnel des fonctions des macrophages par les répresseurs 4E-BP1 et 4E-BP2

  2018cites this paper
• Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers

  2018cites this paper
• Proteomic profile changes associated with diminished expression of T-cell intracellular antigens reveal a hormesis response.

  2018cites this paper
• A Heterologous Cell Model for Studying the Role of T-Cell Intracellular Antigen 1 in Welander Distal Myopathy

  2018cites this paper
• Complex HuR function in pancreatic cancer cells

  2018cites this paper
• The Cross-talk between Tristetraprolin and Cytokines in Cancer.

  2017cites this paper
• RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation

  2017cites this paper
• Tumor protein D52 expression is post-transcriptionally regulated by T-cell intercellular antigen (TIA) 1 and TIA-related protein via mRNA stability.

  2017cites this paper
• Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution.

  2017cites this paper
• LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis

  2017cites this paper
• Posttranslational control of HuR function

  2017cites this paper
• Neurodegeneration and RNA‐binding proteins

  2017cites this paper
• Emerging role of HuR in inflammatory response in kidney diseases.

  2017cites this paper
• RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate

  2017influential citation
• Post-transcriptional regulation of mPGES-1 by the balance between CUGBP1 and miR-574-5p

  2017cites this paper
• The properties of the RNA-binding protein NF90 are considerably modulated by complex formation with NF45.

  2017cites this paper
• The Architecture of the Human RNA-Binding Protein Regulatory Network

  2016cites this paper
• RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7

  2016cites this paper
• Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy

  2016cites this paper
• Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

  2016cites this paper
• T-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor

  2016cites this paper
• Coordinated Action of Two Double-Stranded RNA Binding Motifs and an RGG Motif Enables Nuclear Factor 90 To Flexibly Target Different RNA Substrates.

  2016cites this paper
• Post-transcriptional Mechanisms in Endocrine Regulation

  2016cites this paper
• Post-transcriptional Regulation of Insulin and Insulin Like Growth Factors

  2016cites this paper
• The Polyadenosine RNA-binding Protein, Zinc Finger Cys3His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA*

  2016cites this paper
• The many facets of RNA-binding protein HuR.

  2015cites this paper
• Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells

  2015cites this paper
• The RNA Binding Complexes NF45-NF90 and NF45-NF110 Associate Dynamically with the c-fos Gene and Function as Transcriptional Coactivators*

  2015cites this paper
• Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis

  2015cites this paper
• NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.

  2015cites this paper
• Ilf3 and NF90 functions in RNA biology

  2015cites this paper
• Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly

  2015cites this paper
• RNA-binding proteins, multifaceted translational regulators in cancer.

  2015cites this paper
• Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells

  2015cites this paper
• Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

  2015cites this paper
• Systematic analysis of the Hmga2 3′ UTR identifies many independent regulatory sequences and a novel interaction between distal sites

  2015influential citation
• Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.

  2015cites this paper
• Combinatorial Control of mRNA Fates by RNA-Binding Proteins and Non-Coding RNAs

  2015cites this paper
• Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity

  2015cites this paper
• Post-transcriptional RNA regulons affecting cell cycle and proliferation.

  2014cites this paper
• Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

  2014cites this paper
• Identification des modifications post-traductionnelles d'Ilf3 (Interleukin enhancer binding factor 3) et de NF90 (Nuclear Factor 90) et étude de leur rôle(s) fonctionnel(s)

  2014cites this paper
• Approaches for Dissecting RNA-Binding Protein Networks

  2014cites this paper
• Conditional Knockout of the RNA-Binding Protein HuR in CD4+ T Cells Reveals a Gene Dosage Effect on Cytokine Production

  2014cites this paper
• HuR and other turnover- and translation-regulatory RNA-binding proteins: implications for the kidney.

  2014cites this paper
• A novel multi-target cancer therapy based on destabilization of short-lived mRNAs

  2014cites this paper
• hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3'-UTR and oppositely regulate its expression.

  2014cites this paper
• Hu Antigen R (HuR) Is a Positive Regulator of the RNA-binding Proteins TDP-43 and FUS/TLS

  2014cites this paper
• Post-transcriptional Regulation of Programmed Cell Death 4 (PDCD4) mRNA by the RNA-binding Proteins Human Antigen R (HuR) and T-cell Intracellular Antigen 1 (TIA1)*

  2014cites this paper