The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Cancer Research and Clinical Oncology

• Publication date

  2006-05-17

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00432-006-0092-xPMID 16788843PMCID PMC12161102
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Nutrition and colorectal cancer].

  2007cited by this paper
• Molecular biology in colorectal cancer

  2006cited by this paper
• Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man

  2006cited by this paper
• In vivo quercitrin anti‐inflammatory effect involves release of quercetin, which inhibits inflammation through down‐regulation of the NF‐κB pathway

  2005cited by this paper
• Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial

  2005cited by this paper
• Immunohistochemical expression of Cyclin D1, Cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features

  2004cited by this paper
• Intracellular Polyamine Levels of Intestinal Epithelial Cells in Inflammatory Bowel Disease

  2004cited by this paper
• Nutrition and colorectal cancer

  2004cited by this paper
• Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells.

  2004cited by this paper
• Reduction of Smad3 accelerates re-epithelialization in a murine model of colitis.

  2004cited by this paper
• The prebiotic characteristics of fructooligosaccharides are necessary for reduction of TNBS-induced colitis in rats.

  2003cited by this paper
• Enhanced production of IL‐18 in butyrate‐treated intestinal epithelium by stimulation of the proximal promoter region

  2002cited by this paper
• In vitro alterations in fecal short chain fatty acids and organic anions induced by the destruction of intestinal microflora under hypotonic and aerobic conditions.

  2002influential reference
• The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation.

  2002cited by this paper
• Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats.

  2002cited by this paper
• Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells.

  2001cited by this paper
• Intestinal Trefoil Factor Induces Decay-Accelerating Factor Expression and Enhances the Protective Activities Against Complement Activation in Intestinal Epithelial Cells1

  2001influential reference
• Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27(Kip1) and p21(Waf1).

  2001cited by this paper
• Effect of structural analogues of propionate and butyrate on colon cancer cell growth

  2000cited by this paper
• Relation to Inflammatory Bowel Diseases and Colon Cancer

  1999cited by this paper
• Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP)

  1999cited by this paper
• Short-chain fatty acid in the human colon. Relation to inflammatory bowel diseases and colon cancer.

  1999cited by this paper
• Short-Chain Fatty Acid in the Human Colon

  1999cited by this paper
• Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer.

  1998cited by this paper
• Energy state in HT-29 cells is linked to differentiation

  1997cited by this paper
• COMPARISON OF THE EFFECT OF DIFFERENT SHORT CHAIN FATTY ACIDS ON THE GROWTH AND DIFFERENTIATION OF HUMAN COLONIC CARCINOMA CELL LINESIN VITRO

  1997cited by this paper
• Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells.

  1997influential reference
• Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms.

  1997influential reference
• Apoptosis in small intestinal epithelia from p53-null mice: evidence for a delayed, p53-indepdendent G2/M-associated cell death after γ-irradiation

  1997cited by this paper
• Epithelial cells as sensors for microbial infection.

  1997cited by this paper
• Molecular biology of colorectal cancer.

  1997cited by this paper
• Cancer statistics, 1996

  1996cited by this paper
• Butyrate enema therapy stimulates mucosal repair in experimental colitis in the rat.

  1996cited by this paper
• Effect of quercitrin on acute and chronic experimental colitis in the rat.

  1996cited by this paper
• Wheat bran suppresses potato starch--potentiated colorectal tumorigenesis at the aberrant crypt stage in a rat model.

  1996cited by this paper
• Bacterial fermentation of complex carbohydrate in the human colon.

  1995cited by this paper
• Disruption of colonic electrolyte transport in experimental colitis.

  1995cited by this paper
• Radiation and gut

  1995cited by this paper
• Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

  1995cited by this paper
• Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia.

  1995cited by this paper
• Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity.

  1994cited by this paper
• The nutritional impact of the intestinal microflora.

  1994cited by this paper
• Butyrate production from dietary fibre and protection against large bowel cancer in a rat model.

  1993cited by this paper
• Regulation of c‐myc expression by sodium butyrate in the colon carcinoma cell line Caco‐2

  1993cited by this paper
• Short-chain fatty acid enemas: A cost-effective alternative in the treatment of nonspecific proctosigmoiditis

  1992cited by this paper
• Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis.

  1992cited by this paper
• Rectal irrigation with short-chain fatty acids for distal ulcerative colitis

  1991cited by this paper
• Metabolic and intestinal effects of short-chain fatty acids.

  1990cited by this paper
• Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form.

  1990influential reference
• Cancer statistics

  1989cited by this paper
• Treatment of diversion colitis with short-chain-fatty acid irrigation.

  1989cited by this paper
• Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells.

  1989cited by this paper
• Hapten-induced model of chronic inflammation and ulceration in the rat colon.

  1989cited by this paper
• Genetic alterations during colorectal-tumor development.

  1988cited by this paper
• Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.

  1988cited by this paper
• Effect of dietary fiber on colonic cell proliferation and its relationship to colon carcinogenesis.

  1987cited by this paper
• Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215).

  1986cited by this paper
• Cell Migration Velocities In the Crypts of the Small Intestine After Cytotoxic Insult Are Not Dependent On Mitotic Activity

  1986cited by this paper
• Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.

  1984cited by this paper
• Effect of n-butyrate on cell cycle progression and in situ chromatin structure of L1210 cells.

  1981cited by this paper
• Calcium-dependent phosphorylation of histone H3 in butyrate-treated HeLa cells

  1980cited by this paper
• Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man.

  1980cited by this paper

• Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism

  2025cites this paper
• Tailor-made Biochar enhances the anti-tumour effects of butyrate-glycerides in colorectal cancer.

  2025cites this paper
• Digital Pills: Enhancing patient outcomes through innovative medication management

  2025cites this paper
• Butyrate improves dextran sulfate sodium-induced imbalance of intestinal stem cell homeostasis in broilers

  2025cites this paper
• IL-21 and anti-α4β7 dual therapy during ART promotes immunological and microbiome responses in SIV-infected macaques

  2025cites this paper
• Berry supplementation in healthy volunteers modulates gut microbiota, increases fecal polyphenol metabolites and reduces viability of colon cancer cells exposed to fecal water- a randomized controlled trial.

  2025cites this paper
• Fueling the fire: colonocyte metabolism and its effect on the colonic epithelia

  2025cites this paper
• Short-chain fatty acids: key antiviral mediators of gut microbiota

  2025cites this paper
• Lactiplantibacillus argentoratensis AGMB00912 alleviates diarrhea and promotes the growth performance of piglets during the weaning transition

  2024cites this paper
• Faecalibacterium wellingii sp. nov. and Faecalibacterium langellae sp. nov., description of two novel species aiding to the reclassification of Faecalibacterium species.

  2024cites this paper
• Short-chain fatty acids and cancer.

  2024cites this paper
• Pathophysiological and Clinical Potential of Human Microbiome: Microbe-based Therapeutic Insights.

  2024cites this paper
• Lactiplantibacillus argentoratensis AGMB00912 protects weaning mice from ETEC infection and enhances gut health

  2024cites this paper
• The potential of short-chain fatty acid epigenetic regulation in chronic low-grade inflammation and obesity

  2024cites this paper
• Exploring the effect of butyric acid, a metabolite from periodontopathic bacteria, on primary human melanocytes: An in vitro study.

  2024cites this paper
• Microbiomas y salud humana

  2024cites this paper
• Enhancement of Acetate-Induced Apoptosis of Colorectal Cancer Cells by Cathepsin D Inhibition Depends on Oligomycin A-Sensitive Respiration

  2024cites this paper
• Intestinal Fibrogenesis in Inflammatory Bowel Diseases: Exploring the Potential Role of Gut Microbiota Metabolites as Modulators

  2024cites this paper
• Butyrate Metabolism‐Related Gene Signature in Tumor Immune Microenvironment in Lung Adenocarcinoma: A Comprehensive Bioinformatics Study

  2024cites this paper
• Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

  2024cites this paper
• Effects of liquid delactosed permeate in nursery piglet diets: Improvements in feed conversion with increased post-weaning diarrhea occurrence

  2024cites this paper
• Lactiplantibacillus argentoratensis AGMB00912 alleviates salmonellosis and modulates gut microbiota in weaned piglets: a pilot study

  2024cites this paper
• Microbiota-Derived Natural Products Targeting Cancer Stem Cells: Inside the Gut Pharma Factory

  2023cites this paper
• Epigenetic effects of short-chain fatty acids from the large intestine on host cells

  2023cites this paper
• Growing old together: What we know about the influence of diet and exercise on the aging host's gut microbiome

  2023cites this paper
• Beyond butyrate: microbial fiber metabolism supporting colonic epithelial homeostasis.

  2023cites this paper
• THE SMALL INTESTINAL MICROBIOME: VIBING WITH INTESTINAL STEM CELLS.

  2023cites this paper
• Crosstalk between vitamin status and gut microbiota: The key to maintaining immune homeostasis in the gut

  2023cites this paper
• Dysregulation along the gut microbiota-immune system axis after oral exposure to titanium dioxide nanoparticles: A possible environmental factor promoting obesity-related metabolic disorders.

  2023cites this paper
• Exploring the complex role of gut microbiome in the development of precision medicine strategies for targeting microbial imbalance-induced colon cancer

  2023cites this paper
• Interactions du dioxyde de titane alimentaire avec l’axe microbiote-système immunitaire : un nouvel acteur dans le développement de désordres métaboliques ?

  2022cites this paper
• Cell-free probiotic supernatant (CFS) treatment alleviates indomethacin-induced enterocolopathy in BALB/c mice by down-modulating inflammatory response and oxidative stress: potential alternative targeted treatment

  2022cites this paper
• Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer.

  2022cites this paper
• Comprehensive Analysis of the Butyrate-Metabolism-Related Gene Signature in Tumor Microenvironment-Infiltrating Immune Cells in Clear Cell Renal Cell Carcinoma

  2022cites this paper
• Alleviation of loperamide-induced constipation with sticky rice fermented huangjiu by the regulation of serum neurotransmitters and gut microbiota.

  2022cites this paper
• Differential gene expression in iPSC-derived human intestinal epithelial cell layers following exposure to two concentrations of butyrate, propionate and acetate

  2022cites this paper
• New definition of resistant starch types from the gut microbiota perspectives – a review

  2022cites this paper
• Anti-Cancer Pectins and Their Role in Colorectal Cancer Treatment.

  2022cites this paper
• Tumor microbiome metabolism: A game changer in cancer development and therapy

  2022cites this paper
• Plant Antioxidants Affect Human and Gut Health, and Their Biosynthesis Is Influenced by Environment and Reactive Oxygen Species

  2022cites this paper
• Gut Microbiota: Critical Controller and Intervention Target in Brain Aging and Cognitive Impairment

  2021cites this paper
• Reformulation of processed meat to attenuate potential harmful effects in the gastrointestinal tract – A review of current knowledge and evidence of health prospects

  2021cites this paper
• Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease

  2021cites this paper
• Dietary Fibers: Structural Aspects and Nutritional Implications

  2021cites this paper
• Cardioprotective effects of Fenugreek (Trigonella foenum-graceum) seed extract in streptozotocin induced diabetic rats

  2021cites this paper
• Immunomodulatory Effects of Histone Deacetylation Inhibitors in Graft-vs.-Host Disease After Allogeneic Stem Cell Transplantation

  2021cites this paper
• Prebiotics in atopic dermatitis prevention and management

  2021cites this paper
• The role of Short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis.

  2021cites this paper
• Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function

  2021cites this paper
• Metabolic Modeling to Interrogate Microbial Disease: A Tale for Experimentalists

  2021cites this paper
• Suppressive effects of pectin on colitis-associated colon carcinogenesis

  2021cites this paper
• Xiang Study: an association of breastmilk composition with maternal body mass index and infant growth during the first 3 month of life

  2020cites this paper
• Microbiota and Obesity: Where Are We Now?

  2020cites this paper
• Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health

  2020cites this paper
• Cell wall integrity of pulse modulates in vitro fecal fermentation rate and microbiota composition.

  2020cites this paper
• The Protective Role of Probiotics against Colorectal Cancer

  2020cites this paper
• Gut microbiota and aging-A focus on centenarians.

  2020cites this paper
• Crosstalk between food components and microRNAs: Role in metabolism, nutrition, health and diseases

  2020cites this paper
• Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

  2020cites this paper
• HISTOLOGICAL STUDY OF BROILER CHICKENS COLON GIVEN BUTYRIC ACID SUPPLEMENTS )

  2019cites this paper
• Gut microbial metabolites in depression: understanding the biochemical mechanisms

  2019cites this paper
• Milk Oligosaccharides From Different Cattle Breeds Influence Growth-Related Characteristics of Intestinal Cells

  2019cites this paper
• Mannitol evaluated mineral absorption and bone retention in ovariectomized rats

  2019cites this paper
• The production of short chain fatty acid and colonic development in weaning piglets.

  2019cites this paper
• A Reasonable Diet Promotes Balance of Intestinal Microbiota: Prevention of Precolorectal Cancer

  2019cites this paper
• Gut dysbiosis and its epigenomic impact on disease

  2019cites this paper
• The colon as an energy salvage organ for children with short bowel syndrome.

  2019cites this paper
• Organic matter disappearance and production of short- and branched-chain fatty acids from selected fiber sources used in pet foods by a canine in vitro fermentation model1

  2019cites this paper
• Beneficial Effect of Potato Consumption on Gut Microbiota and Intestinal Epithelial Health

  2019cites this paper
• Pathobiont release from dysbiotic gut microbiota biofilms in intestinal inflammatory diseases: a role for iron?

  2019cites this paper
• Effects of tributyrin on growth performance, intestinal microflora and barrier function of weaned pigs

  2019cites this paper
• Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities

  2019cites this paper
• The significance of microbiome in personalized medicine

  2019cites this paper
• Beyond Gut Instinct: Metabolic Short-Chain Fatty Acids Moderate the Pathogenesis of Alphaherpesviruses

  2019cites this paper
• Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model

  2019cites this paper
• Role of SCFAs in gut microbiome and glycolysis for colorectal cancer therapy

  2019cites this paper
• In vitro colonic fermentation of dietary fibers: Fermentation rate, short-chain fatty acid production and changes in microbiota

  2019cites this paper
• DEVELOPING HIGH THROUGHPUT ORGANOID-BASED PLATFORMS TO STUDY ENTERIC PHYSIOLOGY IN VITRO

  2018cites this paper
• Impact of dietary compounds on cancer-related gut microbiota and microRNA

  2018cites this paper
• Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

  2018cites this paper
• Fructooligosaccharide intake promotes epigenetic changes in the intestinal mucosa in growing and ageing rats

  2018cites this paper
• The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications.

  2018cites this paper
• Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial

  2018cites this paper
• Glyphosate has limited short-term effects on commensal bacterial community composition in the gut environment due to sufficient aromatic amino acid levels.

  2018cites this paper
• Pretreatment and treatment with fructo-oligosaccharides attenuate intestinal mucositis induced by 5-FU in mice

  2018cites this paper
• Butyrate stimulates the growth of human intestinal smooth muscle cells by activation of yes‐associated protein

  2018cites this paper
• Cranberry seed fibre: a promising prebiotic fibre and its fermentation by the probiotic Bacillus coagulans MTCC 5856

  2018cites this paper
• The regulation of host cellular and gut microbial metabolism in the development and prevention of colorectal cancer

  2018cites this paper
• Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells

  2018cites this paper
• Biological Activities of Lactose-Derived Prebiotics and Symbiotic with Probiotics on Gastrointestinal System

  2018cites this paper
• Role of short-chain fatty acids in colonic inflammation, carcinogenesis, and mucosal protection and healing

  2017cites this paper
• Gut microbiome and aging: Physiological and mechanistic insights

  2017cites this paper
• Ingestible Sensors.

  2017cites this paper
• Synbiotic preparation with Lactic acid bacteria and inulin as a functional food: In vivo evaluation of microbial activities, and preneoplastic aberrant crypt foci

  2017cites this paper
• “ OMICS ” LANGUAGE METAGENOMICS IS IN WAIT FOR PRECISION MEDICINE AS A NEW CLINICAL FRONTIER : FOCUS ON COLORECTAL CANCER

  2017cites this paper
• A story of metformin‐butyrate synergism to control various pathological conditions as a consequence of gut microbiome modification: Genesis of a wonder drug?

  2017cites this paper
• Describing the gut microbiome and metabolomic changes in bile acid diarrhoea (BAD)

  2017cites this paper
• Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment

  2017cites this paper
• Gut microbiota, a rising star in hypertension

  2017cites this paper
• Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells

  2017cites this paper