Adaptive deep brain stimulation in a freely moving parkinsonian patient

M. Rosa,M. Arlotti,G. Ardolino,F. Cogiamanian,S. Marceglia,A. di Fonzo,F. Cortese,P. Rampini,A. Priori

Published 2015 in Movement Disorders

ABSTRACT

The future of deep brain stimulation (DBS) for Parkinson's disease (PD) lies in new closed‐loop systems that continuously supply the implanted stimulator with new settings obtained by analyzing a feedback signal related to the patient's current clinical condition.1 The most suitable feedback for PD is subthalamic local field potential (LFP) activity recorded from the stimulating electrode itself.2, 3, 4 This closed‐loop technology known as adaptive DBS (aDBS) recently proved superior to conventional open‐loop DBS (cDBS) in patients with PD.2

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