Homing-Associated Cell Adhesion Molecule (H-CAM/CD44) on Human CD34+ Hematopoietic Progenitor Cells

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Leukemia and Lymphoma

• Publication date

  2000-01-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.3109/10428190009054878PMID 11426626
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Current Topics in Microbiology and Immunology (1993) Volume on Adhesion in Leukocyte Homing and Differentiation (eds D. Dunon, C. R. Mackay, and B. A. Imhof) CD44: a multitude of isoforms with diverse functions

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• Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding

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• Hyaluronate-enhanced hematopoiesis: two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages.

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• Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia

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• Anxiety traits associated with a polymorphism in the serotonin transporter gene regulatory region in the Japanese

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• CD44 isoforms in normal and leukemic hematopoiesis.

  1999cited by this paper
• Expression of homing-associated cell adhesion molecule (H-CAM/CD44) on human CD34+ hematopoietic progenitor cells.

  1999cited by this paper
• Chimeric CD4/CD44 molecules associate with CD44 via the transmembrane region and reduce hyaluronan binding in T cell lines

  1998cited by this paper
• Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells

  1998cited by this paper
• CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes

  1998cited by this paper
• CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes.

  1998cited by this paper
• Cell adhesion molecule expression on CD34+ cells in grafts and time to myeloid and platelet recovery after autologous stem cell transplantation.

  1998cited by this paper
• Diverse effects of anti‐CD44 antibodies on the stromal cell‐mediated support of normal but not leukaemic (CML) haemopoiesis in vitro

  1997cited by this paper
• Antibodies to CD44 enhance adhesion of normal CD34+ cells and acute myeloblastic but not lymphoblastic leukaemia cells to bone marrow stroma

  1997cited by this paper
• Expression mapping of adhesion receptor genes during differentiation of individual hematopoietic precursors.

  1997cited by this paper
• Early onset of immunoglobulin heavy chain gene rearrangements in normal human bone marrow CD34+ cells.

  1997cited by this paper
• Antibodies to the beta 1-integrin chain, CD44, or ICAM-3 stimulate adhesion of blast colony-forming cells and may inhibit their growth.

  1997cited by this paper
• Functional activity of CD44 isoforms in haemopoiesis of the rat

  1997cited by this paper
• CD44-mediated adhesiveness of human hematopoietic progenitors to hyaluronan is modulated by cytokines.

  1997cited by this paper
• Adhesion of human hematopoietic progenitor cells to bone-marrow-derived stromal cells is enhanced by antibodies to CD44.

  1996cited by this paper
• Requirement for CD44 in proliferation and homing of hematopoietic precursor cells

  1996cited by this paper
• An antibody to CD44 enhances hematopoiesis in long-term marrow cultures.

  1996cited by this paper
• Signaling through CD44 Is Mediated by Tyrosine Kinases

  1996cited by this paper
• CD44 and hyaluronan binding by human myeloid cells.

  1996cited by this paper
• Altered patterns of CD44 epitope expression in human chronic and acute myeloid leukemia.

  1996cited by this paper
• A cysteine residue located in the transmembrane domain of CD44 is important in binding of CD44 to hyaluronic acid

  1996cited by this paper
• Glycosylation of CD44 negatively regulates its recognition of hyaluronan

  1995cited by this paper
• Role of CD44 cytoplasmic domain in hyaluronan binding

  1995cited by this paper
• Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia.

  1995cited by this paper
• Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation

  1995cited by this paper
• Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons

  1995cited by this paper
• Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein.

  1994cited by this paper
• ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

  1994cited by this paper
• Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of fibronectin: cooperation between the integrin alpha 4 beta 1 and the CD44 adhesion receptor.

  1994cited by this paper
• Inducible binding of human lymphocytes to hyaluronate via CD44 does not require cytoskeleton association but does require new protein synthesis.

  1994cited by this paper
• CD44 mediates hyaluronan binding by human myeloid KG1A and KG1 cells.

  1994cited by this paper
• Ligand binding specificity of alternatively spliced CD44 isoforms. Recognition and binding of hyaluronan by CD44R1.

  1994cited by this paper
• Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function

  1994cited by this paper
• Antibody‐induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody

  1993cited by this paper
• The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat.

  1993cited by this paper
• Splicing choice from ten variant exons establishes CD44 variability.

  1993cited by this paper
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  1993cited by this paper
• Identification of hyaluronic acid binding sites in the extracellular domain of CD44

  1993cited by this paper
• CD44 and its interaction with extracellular matrix.

  1993cited by this paper
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  1993cited by this paper
• The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44.

  1993cited by this paper
• Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition

  1992cited by this paper
• Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody

  1992cited by this paper
• Phosphorylation of CD44 in vivo requires both Ser323 and Ser325, but does not regulate membrane localization or cytoskeletal interaction in epithelial cells.

  1992cited by this paper
• CD44: the hyaluronan receptor.

  1992cited by this paper
• Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma.

  1992cited by this paper
• CD44H regulates tumor cell migration on hyaluronate-coated substrate

  1992cited by this paper
• Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain.

  1992cited by this paper
• The lymphoma transmembrane glycoprotein GP85 (CD44) is a novel guanine nucleotide-binding protein which regulates GP85 (CD44)-ankyrin interaction.

  1992cited by this paper
• Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells.

  1992cited by this paper
• Cell interaction molecules and cytokines which participate in B lymphopoiesis.

  1992cited by this paper
• Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.

  1992cited by this paper
• Functional role of CD44 (Pgp-1) on activated B cells

  1991cited by this paper
• CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines.

  1991cited by this paper
• Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte "homing" receptor expressed by hemopoietic cells

  1991cited by this paper
• Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages

  1991cited by this paper
• High levels of CD44 expression distinguish virgin from antigen-primed B cells

  1991cited by this paper
• The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate‐bearing cells.

  1991cited by this paper
• Sequence of the bovine CD44 cDNA: comparison with human and mouse sequences.

  1991cited by this paper
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• A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells.

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• CD44 is the principal cell surface receptor for hyaluronate.

  1990cited by this paper
• Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule.

  1990cited by this paper
• Human hematopoietic precursors in long-term culture: single CD34+ cells that lack detectable T cell, B cell, and myeloid cell antigens produce multiple colony-forming cells when cultured with marrow stromal cells

  1990cited by this paper
• The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins [published erratum appears in J Cell Biol 1991 Feb;112(3):following 513]

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• Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.

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• The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins.

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• CD44--a molecule involved in leukocyte adherence and T-cell activation.

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