ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin

Reduction of ATAD5 extends the lifespan of replication factories by retaining PCNA and other replisome proteins on chromatin, leading to an increase in inactive replication factories and reduced overall replication rate.

• Publication year

  2013

• Venue

  Journal of Cell Biology

• Publication date

  2013-01-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201206084PMID 23277426PMCID 3542800
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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