B-GATA transcription factors – insights into their structure, regulation, and role in plant development

GATA transcription factors are evolutionarily conserved transcriptional regulators that recognize promoter elements with a G-A-T-A core sequence. In comparison to animal genomes, the GATA transcription factor family in plants is comparatively large with approximately 30 members. Here, we review the current knowledge on B-GATAs, one of four GATA factor subfamilies from Arabidopsis thaliana. We show that B-GATAs can be subdivided based on structural features and their biological function into family members with a C-terminal LLM- (leucine–leucine–methionine) domain or an N-terminal HAN- (HANABA TARANU) domain. The paralogous GNC (GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED) and CGA1/GNL (CYTOKININ-INDUCED GATA1/GNC-LIKE) are introduced as LLM-domain containing B-GATAs from Arabidopsis that control germination, greening, senescence, and flowering time downstream from several growth regulatory signals. Arabidopsis HAN and its monocot-specific paralogs from rice (NECK LEAF1), maize (TASSEL SHEATH1), and barley (THIRD OUTER GLUME) are HAN-domain-containing B-GATAs with a predominant role in embryo development and floral development. We also review GATA23, a regulator of lateral root initiation from Arabidopsis that is closely related to GNC and GNL but has a degenerate LLM-domain that is seemingly specific for the Brassicaceae family. The Brassicaceae-specific GATA23 and the monocot-specific HAN-domain GATAs provide evidence that neofunctionalization of B-GATAs was used during plant evolution to expand the functional repertoire of these transcription factors.

• Publication year

  2015

• Venue

  Frontiers in Plant Science

• Publication date

  2015-02-23

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.3389/fpls.2015.00090PMID 25755661PMCID 4337238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gibberellin – Mechanism of Action

  2014cited by this paper
• Arabidopsis JAGGED links floral organ patterning to tissue growth by repressing Kip-related cell cycle inhibitors

  2014cited by this paper
• Functional Diversification within the Family of B-GATA Transcription Factors through the Leucine-Leucine-Methionine Domain1[C][W][OPEN]

  2014influential reference
• Cross-Repressive Interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the Control of Greening, Cold Tolerance, and Flowering Time in Arabidopsis1[W][OPEN]

  2013influential reference
• Convergence of auxin and gibberellin signaling on the regulation of the GATA transcription factors GNC and GNL in Arabidopsis thaliana

  2013cited by this paper
• Transcription Repressor HANABA TARANU Controls Flower Development by Integrating the Actions of Multiple Hormones, Floral Organ Specification Genes, and GATA3 Family Genes in Arabidopsis[W]

  2013influential reference
• Stable establishment of cotyledon identity during embryogenesis in Arabidopsis by ANGUSTIFOLIA3 and HANABA TARANU

  2012cited by this paper
• Regulation of Root Greening by Light and Auxin/Cytokinin Signaling in Arabidopsis[W]

  2012cited by this paper
• Functional Characterization of the GATA Transcription Factors GNC and CGA1 Reveals Their Key Role in Chloroplast Development, Growth, and Division in Arabidopsis1[W][OA]

  2012cited by this paper
• The auxin signalling network translates dynamic input into robust patterning at the shoot apex

  2011cited by this paper
• The TOPLESS Interactome: A Framework for Gene Repression in Arabidopsis1[W][OA]

  2011cited by this paper
• GNC and CGA1 Modulate Chlorophyll Biosynthesis and Glutamate Synthase (GLU1/Fd-GOGAT) Expression in Arabidopsis

  2011cited by this paper
• A Conserved Mechanism of Bract Suppression in the Grass Family[W][OA]

  2010cited by this paper
• The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo.

  2010influential reference
• PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.

  2010cited by this paper
• A novel aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity.

  2010cited by this paper
• The GATA-type transcription factors GNC and GNL/CGA1 repress gibberellin signaling downstream from DELLA proteins and PHYTOCHROME-INTERACTING FACTORS.

  2010influential reference
• NECK LEAF 1, a GATA type transcription factor, modulates organogenesis by regulating the expression of multiple regulatory genes during reproductive development in rice

  2009cited by this paper
• The PLASTID DIVISION1 and 2 Components of the Chloroplast Division Machinery Determine the Rate of Chloroplast Division in Land Plant Cell Differentiation[C][W]

  2009cited by this paper
• Coordinated regulation of Arabidopsis thaliana development by light and gibberellins

  2008cited by this paper
• A molecular framework for light and gibberellin control of cell elongation

  2008influential reference
• Type B Response Regulators of Arabidopsis Play Key Roles in Cytokinin Signaling and Plant Development[W]

  2008cited by this paper
• Two GATA Transcription Factors Are Downstream Effectors of Floral Homeotic Gene Action in Arabidopsis1[W][OA]

  2008cited by this paper
• Characterization of a Unique GATA Family Gene That Responds to Both Light and Cytokinin in Arabidopsis thaliana

  2007cited by this paper
• The F-box protein TIR1 is an auxin receptor

  2005cited by this paper
• Loss of function of four DELLA genes leads to light- and gibberellin-independent seed germination in Arabidopsis

  2005cited by this paper
• AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana

  2005cited by this paper
• Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry.

  2005cited by this paper
• Plant Development Is Regulated by a Family of Auxin Receptor F Box Proteins

  2005cited by this paper
• CONSTANS Activates SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 through FLOWERING LOCUS T to Promote Flowering in Arabidopsis1[w]

  2005cited by this paper
• Genetic analysis of Arabidopsis GATA transcription factor gene family reveals a nitrate-inducible member important for chlorophyll synthesis and glucose sensitivity.

  2005cited by this paper
• AUXIN RESPONSE FACTOR 2 (ARF2): a pleiotropic developmental regulator.

  2005cited by this paper
• Plant development is regulated by a family of auxin receptor F box proteins.

  2005cited by this paper
• HANABA TARANU Is a GATA Transcription Factor That Regulates Shoot Apical Meristem and Flower Development in Arabidopsisw⃞

  2004influential reference
• The GATA Family of Transcription Factors in Arabidopsis and Rice1

  2004influential reference
• Gibberellin regulates Arabidopsis floral development via suppression of DELLA protein function

  2004cited by this paper
• The Arabidopsis F-Box Protein SLEEPY1 Targets Gibberellin Signaling Repressors for Gibberellin-Induced Degradation

  2004cited by this paper
• Global Transcription Profiling Reveals Multiple Sugar Signal Transduction Mechanisms in Arabidopsis

  2004cited by this paper
• Genome-Wide Reprogramming of Primary and Secondary Metabolism, Protein Synthesis, Cellular Growth Processes, and the Regulatory Infrastructure of Arabidopsis in Response to Nitrogen1[w]

  2004cited by this paper
• Microarray Analysis of the Nitrate Response in Arabidopsis Roots and Shoots Reveals over 1,000 Rapidly Responding Genes and New Linkages to Glucose, Trehalose-6-Phosphate, Iron, and Sulfate Metabolism1[w]

  2003cited by this paper
• The SOC1 MADS-box gene integrates vernalization and gibberellin signals for flowering in Arabidopsis.

  2003cited by this paper
• Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis

  2003cited by this paper
• GLK gene pairs regulate chloroplast development in diverse plant species.

  2002cited by this paper
• The fungal GATA factors.

  2000cited by this paper
• Distinct roles of CONSTANS target genes in reproductive development of Arabidopsis.

  2000cited by this paper
• Independent regulation of flowering by phytochrome B and gibberellins in Arabidopsis.

  1999cited by this paper
• Key Residues Characteristic of GATA N-fingers Are Recognized By FOG*

  1998cited by this paper
• EVOLUTION OF LIGHT-REGULATED PLANT PROMOTERS.

  1998cited by this paper
• FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation.

  1997cited by this paper
• A tobacco cDNA clone encoding a GATA-1 zinc finger protein homologous to regulators of nitrogen metabolism in fungi

  1993cited by this paper

• B‐GATA factors are required for nitrogen‐responsive growth in Physcomitrium patens and Arabidopsis thaliana

  2026cites this paper
• Chromosome-scale genome assembly of the Santina and Regina varieties of Prunus avium

  2026cites this paper
• Genome-wide identification of the GATA transcription factor family in ten Cucurbitaceae species and expression analysis of ClGATA genes in watermelon stress responses

  2026cites this paper
• GATA TF Class Classifier: AI-based functional prediction and taxonomic profiling in angiosperm GATA transcription factors

  2025cites this paper
• Genome-wide identification, phylogenetic and expression pattern analysis of GATA gene family in Cerasus humilis

  2025cites this paper
• GATA8‐Mediated Antiviral Defence Is Countered by Tomato Chlorosis Virus‐Encoded Pathogenicity Protein p27

  2025cites this paper
• Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of amino acids and their derivatives biosynthesis in Polygonatum

  2025cites this paper
• CdGLK1 Transcription Factor Confers Low-Light Tolerance in Bermudagrass via Coordinated Upregulation of Photosynthetic Genes and Enhanced Antioxidant Enzyme Activity

  2025cites this paper
• The OsGATA gene family as a promising candidate for applying the CrISPr/Cas genome editing technology to improve the nutritional and yield qualities of rice (Oryza sativa L.)

  2025cites this paper
• Contrasting Roles of Plant GATA21/22 Transcriptional Regulators in Defense Against Fungal and Bacterial Pathogens.

  2025cites this paper
• ESSENTIAL MEIOTIC ENDONUCLEASE 1 is required for chloroplast development and DNA repair in rice

  2025cites this paper
• Genome-wide characterization and expression analysis of the GATA transcription factor family in response to salt and drought stress in barley (Hordeum vulgare L.)

  2025cites this paper
• Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha

  2024cites this paper
• PpGATA4 mediates fruit softening and transcriptionally regulates PpEXPA1 in peach (Prunus persica).

  2024cites this paper
• The OsNL1‐OsTOPLESS2‐OsMOC1/3 pathway regulates high‐order tiller outgrowth in rice

  2024influential citation
• Genome-wide identification, characterization and expression profiles of FORMIN gene family in cotton (Gossypium Raimondii L.)

  2024cites this paper
• Mining GATA Transcription Factor Encoding Genes in The Cocoa Tree (Theobroma cacao L.) Suggests Their Potential Roles in Embryo Development and Biotic Stress Response

  2024cites this paper
• Genome-Wide Identification of a Maize Chitinase Gene Family and the Induction of Its Expression by Fusarium verticillioides (Sacc.) Nirenberg (1976) Infection

  2024cites this paper
• In silico approach to investigate the potential HKT gene responsive to salt stress in rice

  2024cites this paper
• Identification and expression profiling of SmGATA genes family involved in response to light and phytohormones in eggplant

  2024cites this paper
• Nitrate Signaling and Its Role in Regulating Flowering Time in Arabidopsis thaliana

  2024cites this paper
• The Putative GATA Transcription Factor SbGATA22 as a Novel Regulator of Dhurrin Biosynthesis

  2024cites this paper
• Genome-wide identification and salt stress-expression analysis of the dehydrin gene family in Chenopodium quinoa

  2024cites this paper
• GATA family transcription factors in alga Chlamydomonas reinhardtii

  2024cites this paper
• Characterization of promoter elements of isoprene‐responsive genes and the ability of isoprene to bind START domain transcription factors

  2023cites this paper
• Promoter of Nitrate Reductase Gene Behaves Differently Under Salinity Stress in Contrasting Rice Genotype

  2023cites this paper
• The intertwining of Zn-finger motifs and abiotic stress tolerance in plants: Current status and future prospects

  2023cites this paper
• Plant tolerance to salinity stress: Regulating transcription factors and their functional role in the cellular transcriptional network

  2023cites this paper
• Genetic and Epigenetic Responses of Autochthonous Grapevine Cultivars from the ‘Epirus’ Region of Greece upon Consecutive Drought Stress

  2023cites this paper
• Genome-wide identification of QTLs associated with iron deficiency tolerance in soybean reveals GATA12 as the integrator of iron signaling in roots

  2023cites this paper
• Rice OsGATA16 is a positive regulator for chlorophyll biosynthesis and chloroplast development.

  2023cites this paper
• Genomic and transcriptomic analyses reveal polygenic architecture for ecologically important traits in aspen (Populus tremuloides Michx.)

  2023cites this paper
• Comprehensive Analysis and Characterization of the GATA Gene Family, with Emphasis on the GATA6 Transcription Factor in Poplar

  2023influential citation
• The activation of the NAC transcription factor by Poplar PtrGATA9 facilitates the secondary cell wall deposition of interfascicular fiber cell in Arabidopsis

  2023influential citation
• Heat responsive gene StGATA2 functions in plant growth, photosynthesis and antioxidant defense under heat stress conditions

  2023cites this paper
• GATA transcription factor in common bean: A comprehensive genome-wide functional characterization, identification, and abiotic stress response evaluation

  2023cites this paper
• TaEF1A is involved in low phosphorus stress responses and affects root development

  2023cites this paper
• Transcriptomic and functional analyses reveal the molecular mechanisms underlying Fe-mediated tobacco resistance to potato virus Y infection

  2023cites this paper
• Streamlined regulation of chloroplast development

  2023cites this paper
• Integrated metabolomic and transcriptomic analyses of two peanut (Arachis hypogaea L.) cultivars differing in amino acid metabolism of the seeds.

  2022cites this paper
• Genomic architecture of promoters and transcriptional regulation of candidate genes in rice involved in tolerance to anaerobic germination

  2022cites this paper
• Plant GATA Factors: Their Biology, Phylogeny, and Phylogenomics.

  2022cites this paper
• WHIRLIES Are Multifunctional DNA-Binding Proteins With Impact on Plant Development and Stress Resistance

  2022cites this paper
• Flower color mutation, pink to orange, through CmGATA4 - CCD4a-5 module regulates carotenoids degradation in chrysanthemum.

  2022cites this paper
• Genome-Wide Characterization and Expression Analysis of GATA Transcription Factors in Response to Methyl Jasmonate in Salvia miltiorrhiza

  2022cites this paper
• Genome-wide Association Analysis Reveals a Novel QTL CsFS1 for Fruit Skin Color in Cucumber

  2022cites this paper
• Genome-Wide Identification, Evolution, and Expression Pattern Analysis of the GATA Gene Family in Tartary Buckwheat (Fagopyrum tataricum)

  2022cites this paper
• MeGATAs, functional generalists in interactions between cassava growth and development, and abiotic stresses

  2022cites this paper
• Functional identification of moss PpGATA1 provides insights into the evolution of LLM-domain B-GATA transcription factors in plants.

  2022cites this paper
• Identification and functional analysis of transcription factors related to coconut (Cocos nucifera L.) endosperm development based on ATAC-seq

  2022cites this paper
• PbrARF4 Contributes to Calyx Shedding of Fruitlets in ‘Dangshan Suli’ Pear by Partly Regulating the Expression of Abscission Genes

  2022cites this paper
• Genetic variation in GmCRP contributes to nodulation in soybean (Glycine max Merr.)

  2022cites this paper
• Exogenous 24-epibrassinolide alleviates chilling injury in peach fruit through modulating PpGATA12-mediated sucrose and energy metabolisms.

  2022cites this paper
• Genome‑wide identification, phylogenetic and expression pattern analysis of GATA family genes in foxtail millet (Setaria italica)

  2022cites this paper
• Genome-wide association analysis reveals a novel QTL CsPC1 for pericarp color in cucumber

  2022cites this paper
• A novel sweetpotato GATA transcription factor, IbGATA24, interacting with IbCOP9-5a positively regulates drought and salt tolerance

  2021cites this paper
• From blooms to brooms.

  2021cites this paper
• Comprehensive Comparative Analysis of the GATA Transcription Factors in Four Rosaceae Species and Phytohormonal Response in Chinese Pear (Pyrus bretschneideri) Fruit

  2021influential citation
• Chloroplast development in green plant tissues: the interplay between light, hormone, and transcriptional regulation.

  2021cites this paper
• CaAIL1 Acts Positively in Pepper Immunity Against Ralstonia Solanacearum by Repressing Negative Regulators.

  2021cites this paper
• Engineering chloroplast development in rice through cell‐specific control of endogenous genetic circuits

  2021cites this paper
• Genome-wide Association Analysis Reveals a Novel QTL CsFS1 for Fruit Skin Color in Cucumber

  2021cites this paper
• Arabidopsis EGY1 Is Critical for Chloroplast Development in Leaf Epidermal Guard Cells

  2021cites this paper
• Genome-wide identification and function characterization of GATA transcription factors during development and in response to abiotic stresses and hormone treatments in pepper

  2021cites this paper
• PdGNC confers drought tolerance by mediating stomatal closure resulted from NO and H2 O2 production via the direct regulation of PdHXK1 expression in Populus.

  2021cites this paper
• OsGATA16, a GATA Transcription Factor, Confers Cold Tolerance by Repressing OsWRKY45–1 at the Seedling Stage in Rice

  2021cites this paper
• Overexpression of SlGATA17 Promotes Drought Tolerance in Transgenic Tomato Plants by Enhancing Activation of the Phenylpropanoid Biosynthetic Pathway

  2021cites this paper
• Genome-wide identification of the GATA transcription factor family and their expression patterns under temperature and salt stress in Aspergillus oryzae

  2021cites this paper
• Characterization of a High Hierarchical Regulator, PtrGATA12, Functioning in Differentially Regulating Secondary Wall Component Biosynthesis in Populus trichocarpa

  2021cites this paper
• TDIF regulates auxin accumulation and modulates auxin sensitivity to enhance both adventitious root and lateral root formation in poplar trees.

  2020cites this paper
• Cytosolic GLUTAMINE SYNTHETASE1;1 Modulates Metabolism and Chloroplast Development in Roots1[OPEN]

  2020cites this paper
• The morphology, molecular development and ecological function of pseudonectaries on Nigella damascena (Ranunculaceae) petals

  2020cites this paper
• Genome-wide characterization of the abscisic acid-, stress- and ripening-induced (ASR) gene family in wheat (Triticum aestivum L.)

  2020cites this paper
• DOF, MYB and TCP transcription factors: Their possible roles on barley germination and seedling establishment.

  2020cites this paper
• A GATA Transcription Factor from Soybean (Glycine max) Regulates Chlorophyll Biosynthesis and Suppresses Growth in the Transgenic Arabidopsis thaliana

  2020cites this paper
• The GATA Gene Family in Chickpea: Structure Analysis and Transcriptional Responses to Abscisic Acid and Dehydration Treatments Revealed Potential Genes Involved in Drought Adaptation

  2020cites this paper
• MiR396 is involved in plant response to vernalization and flower development in Agrostis stolonifera

  2020cites this paper
• Histone modification as a potential preventative and therapeutic approach for cardiovascular disease

  2020cites this paper
• Genome-Wide Association Study of Root System Development at Seedling Stage in Rice

  2020cites this paper
• Transcriptomic profiles of non-embryogenic and embryogenic callus cells in a highly regenerative upland cotton line (Gossypium hirsutum L.)

  2020cites this paper
• Characteristics of the Aspergillus oryzae GATA Transcription Factor Family and Expression Analysis under Temperature or Salt Stresses

  2020cites this paper
• Recent Advances in Genetic Regulation of Chlorophyll Metabolism in Plants

  2020cites this paper
• Transcriptomic pro les of non-embryogenic and embryogenic callus cells in a highly regenerative Upland Cotton line (Gossypium hirsutum L.)

  2020cites this paper
• Integrative inference of transcriptional networks in Arabidopsis yields novel ROS signalling regulators

  2020cites this paper
• Genome-wide Identification of the Aspergillus oryzae GATA Transcription Factor Gene Family and expression Analysis under Temperature or Salt Stresses

  2020cites this paper
• Transcriptomic pro les of non-embryogenic and embryogenic callus cells in a highly regenerative Upland Cotton line (Gossypium hirsutum L.)

  2020cites this paper
• Integrative inference of transcriptional networks in Arabidopsis

  2020cites this paper
• Comparative analysis of salt responsive gene regulatory networks in rice and Arabidopsis

  2019cites this paper
• The GATA transcription factor GNC plays an important role in photosynthesis and growth in poplar

  2019cites this paper
• The Complex Genetic Architecture of Early Root and Shoot Traits in Flax Revealed by Genome-Wide Association Analyses

  2019cites this paper
• GATA and Phytochrome Interacting Factor Transcription Factors Regulate Light-Induced Vindoline Biosynthesis in Catharanthus roseus1[OPEN]

  2019cites this paper
• Dissecting the genetic control of flowering time for improved phenological adaptation in narrow-leafed lupin (Lupinus angustifolius L.)

  2019cites this paper
• Molecular and Environmental Regulation of Root Development.

  2019cites this paper
• Update: Improving the Efficiency of Photosynthetic Carbon Reactions1[OPEN]

  2019cites this paper
• Genome-wide identification and analysis of the evolution and expression patterns of the GATA transcription factors in three species of Gossypium genus.

  2019cites this paper
• The wheat LLM-domain-containing transcription factor TaGATA1 positively modulates host immune response to Rhizoctonia cerealis

  2019influential citation
• Time-based LC-MS/MS analysis provides insights into early responses to mechanical wounding, a major trigger to agarwood formation in Aquilaria malaccensis Lam

  2019cites this paper
• PropaNet: Time-Varying Condition-Specific Transcriptional Network Construction by Network Propagation

  2019cites this paper
• Transcriptional Regulation of Abscission Zones

  2019cites this paper
• Transcriptional control for the chlorophyll metabolism

  2019cites this paper