Identification of the Mg2+-binding site in the P-type ATPase and phosphatase members of the HAD (haloacid dehalogenase) superfamily by structural similarity to the response regulator protein CheY.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Biochemical Journal

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1042/0264-6021:3390223PMID 10191250PMCID PMC1220148
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure of the calcium pump from sarcoplasmic reticulum at 8-Å resolution

  1998cited by this paper
• A New Class of Phosphotransferases Phosphorylated on an Aspartate Residue in an Amino-terminal DXDX(T/V) Motif*

  1998cited by this paper
• The catalytic domain of the P-type ATPase has the haloacid dehalogenase fold.

  1998cited by this paper
• Three-dimensional map of the plasma membrane H+-ATPase in the open conformation

  1998cited by this paper
• Human l‐3‐phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate

  1997cited by this paper
• Crystal structure of the I domain from integrin alpha2beta1.

  1997cited by this paper
• Three-dimensional Structure of l-2-Haloacid Dehalogenase from Xanthobacter autotrophicus GJ10 Complexed with the Substrate-analogue Formate*

  1997cited by this paper
• Paracatalytic Inactivation of L-2-Haloacid Dehalogenase from Pseudomonas sp. YL by Hydroxylamine

  1997cited by this paper
• Structural organization, ion transport, and energy transduction of P-type ATPases.

  1996cited by this paper
• Functional Expression of Gastric H+,K+-ATPase and Site-directed Mutagenesis of the Putative Cation Binding Site and the Catalytic Center (*)

  1996cited by this paper
• A circularly permuted alpha-amylase-type alpha/beta-barrel structure in glucan-synthesizing glucosyltransferases.

  1996cited by this paper
• Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold.

  1996cited by this paper
• Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).

  1995cited by this paper
• Reaction Mechanism of L-2-Haloacid Dehalogenase of Pseudomonas sp. YL

  1995cited by this paper
• Organization of P-type ATPases: significance of structural diversity.

  1995cited by this paper
• Bacterial chemotaxis: a field in motion.

  1995cited by this paper
• Comprehensive site-directed mutagenesis of L-2-halo acid dehalogenase to probe catalytic amino acid residues.

  1995cited by this paper
• Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search.

  1994cited by this paper
• Structure of the Mg(2+)-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis.

  1994cited by this paper
• Magnesium binding to the bacterial chemotaxis protein CheY results in large conformational changes involving its functional surface.

  1994cited by this paper
• Structural conservation in the CheY superfamily.

  1993cited by this paper
• Protein structure comparison by alignment of distance matrices.

  1993cited by this paper
• Structure of the Clostridium thermocellum gene licB and the encoded beta-1,3-1,4-glucanase. A catalytic region homologous to Bacillus lichenases joined to the reiterated domain of clostridial cellulases.

  1992cited by this paper
• Purification and Characterization of Phosphoglycolate Phosphatase from the Cyanobacterium Coccochloris peniocystis.

  1991cited by this paper
• Identification of an extracytoplasmic region of H+,K(+)-ATPase labeled by a K(+)-competitive photoaffinity inhibitor.

  1991cited by this paper
• Refined crystal structure of the triphosphate conformation of H‐ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

  1990cited by this paper
• Characterization of trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase of Saccharomyces cerevisiae.

  1989cited by this paper
• Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products.

  1988cited by this paper
• Effect of metal bound to the substrate site on calcium release from the phosphoenzyme intermediate of sarcoplasmic reticulum ATPase.

  1987cited by this paper
• The synthesis of mannose 1-phosphate in brain.

  1985cited by this paper
• Effect of divalent cation bound to the ATPase of sarcoplasmic reticulum. Activation of phosphoenzyme hydrolysis by Mg2+.

  1983cited by this paper
• Source of the oxygen in the C-O-P linkage of the acyl phosphate in transport adenosine triphosphatases.

  1973cited by this paper
• The influence of some cations on an adenosine triphosphatase from peripheral nerves.

  1957cited by this paper

• Molecular Characterization of OsHAD Phosphoprotein: Expression, Catalytic Properties, and Functional Annotation.

  2026cites this paper
• ICARUS: flexible protein structural alignment based on Protein Units

  2023cites this paper
• Microbial 5′-nucleotidases: their characteristics, roles in cellular metabolism, and possible practical applications

  2021cites this paper
• Comparative proteomic analysis to annotate the structural and functional association of the hypothetical proteins of S. maltophilia k279a and predict potential T and B cell targets for vaccination

  2021cites this paper
• Deciphering the Mechanism of Inhibition of SERCA1a by Sarcolipin Using Molecular Simulations

  2019influential citation
• Chapter 4: Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site

  2018cites this paper
• Dehalogenases: From Improved Performance to Potential Microbial Dehalogenation Applications

  2018cites this paper
• Characterization of novel gene targets involved in biofilm formation and antibiotic susceptibility from a Staphylococcus aureus USA300 bursa aurealis transposon library

  2018cites this paper
• Structural and Expression Analysis of Salinity Stress Responsive Phosphoserine Phosphatase from Brassica juncea (L.)

  2017cites this paper
• OsHAD1, a Haloacid Dehalogenase-Like APase, Enhances Phosphate Accumulation1

  2017cites this paper
• Origin of Life and the Phosphate Transfer Catalyst

  2017cites this paper
• Strategies for characterisation of the unexplored human phosphoproteome

  2017cites this paper
• Chemical Approaches to Studying Labile Amino Acid Phosphorylation

  2017cites this paper
• Extensive non-canonical phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics

  2017cites this paper
• Structure and mechanism of a bacterial haloalcohol dehalogenase

  2017cites this paper
• Enzyme engineering of a haloacid dehalogenase-like phosphatase from Thermotoga neopolitana for optimization of substrate specificity

  2016cites this paper
• Identification, Heterologous Expression, and Functional Characterization of Bacillus subtilis YutF, a HAD Superfamily 5'-Nucleotidase with Broad Substrate Specificity

  2016cites this paper
• Identification of Drug Targets in Helicobacter pylori by in silico Analysis: Possible Therapeutic Implications for Gastric cancer.

  2015cites this paper
• Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.

  2015cites this paper
• Probing Mechanistic Similarities Between Response Regulator Signaling Proteins and HAD Phosphatases

  2015cites this paper
• Analysis of Haloacid Dehalogenase superfamily members and functional assignment of Structural Genomics proteins

  2014cites this paper
• Chemistry and Chemical Biology

  2014cites this paper
• Phosphorylation pattern of Rubisco activase in Arabidopsis leaves.

  2014cites this paper
• Mannitol metabolism in brown algae involves a new phosphatase family.

  2014cites this paper
• Human HAD phosphatases: structure, mechanism, and roles in health and disease

  2013cites this paper
• The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65

  2013cites this paper
• 8.2 Structure-Function Relationships in P-Type ATPases

  2012cites this paper
• The Crystal Structure of the Lipid II-degrading Bacteriocin Syringacin M Suggests Unexpected Evolutionary Relationships between Colicin M-like Bacteriocins

  2012cites this paper
• P-type ATPases.

  2011cites this paper
• New targets for antibacterial design: Kdo biosynthesis and LPS machinery transport to the cell surface.

  2011cites this paper
• Focus on phosphoaspartate and phosphoglutamate

  2011influential citation
• Structural identification of cation binding pockets in the plasma membrane proton pump

  2010cites this paper
• The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump

  2010cites this paper
• Biochemical analysis of the phosphatase domain of the human soluble epoxide hydrolase (sEH)

  2010cites this paper
• Functional Neighbors: Inferring Relationships between Nonhomologous Protein Families Using Family-Specific Packing Motifs

  2010cites this paper
• Rolle von Chronophin für die Cofilin-vermittelte Aktin-Dynamik in astrozytären Tumorzellen

  2010cites this paper
• Activity-based functional annotation of unknown proteins : HAD-like hydrolases from E. coli and S. cerevisiae.

  2010cites this paper
• Central and storage carbon metabolism of the brown alga Ectocarpus siliculosus: insights into the origin and evolution of storage carbohydrates in Eukaryotes.

  2010cites this paper
• Kdo: a critical monosaccharide for bacteria viability.

  2010cites this paper
• Identification of family-specific residue packing motifs and their use for structure-based protein function prediction: II. Case studies and applications

  2009cites this paper
• Structural enzymology of dormancy related proteins from Mycobacterium tuberculosis

  2009cites this paper
• Accuracy analysis of multiple structure alignments

  2009cites this paper
• Functional Role for a Conserved Aspartate in the Spo0E Signature Motif Involved in the Dephosphorylation of the Bacillus subtilis Sporulation Regulator Spo0A*

  2008cites this paper
• 1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis.

  2008cites this paper
• Structural aspects of ion pumping by Ca2+-ATPase of sarcoplasmic reticulum.

  2008cites this paper
• Functional Neighbors: Inferring Relationships between Non-Homologous Protein Families Using Family-Specific Packing Motifs

  2008cites this paper
• The characterisation of mammalian PHOSPHO1 : an enzyme involved in bone mineralisation?

  2007cites this paper
• Sulfate acts as phosphate analog on the monomeric catalytic fragment of the CPx-ATPase CopB from Sulfolobus solfataricus.

  2007cites this paper
• Insulin Controls Subcellular Localization and Multisite Phosphorylation of the Phosphatidic Acid Phosphatase, Lipin 1*

  2007cites this paper
• Structural and mutational analyses reveal the functional role of active-site Lys-154 and Asp-173 of Salmonella typhimurium AphA protein.

  2007cites this paper
• Common patterns and unique features of P-type ATPases: a comparative view on the KdpFABC complex from Escherichia coli (Review)

  2007cites this paper
• Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

  2006cites this paper
• Prokaryotic Kdp-ATPase: Recent Insights into the Structure and Function of KdpB

  2006cites this paper
• CadA, the Cd2+-ATPase from Listeria monocytogenes, can use Cd2+ as co-substrate.

  2006cites this paper
• The presence of PHOSPHO1 in matrix vesicles and its developmental expression prior to skeletal mineralization.

  2006cites this paper
• Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase.

  2006cites this paper
• Evolutionary genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes.

  2006cites this paper
• The C. elegans lethal gut-obstructed gob-1 gene is trehalose-6-phosphate phosphatase.

  2005cites this paper
• Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.

  2005cites this paper
• Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class.

  2005cites this paper
• Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity.

  2005cites this paper
• How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase.

  2004cites this paper
• Superfamily active site templates

  2004cites this paper
• Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues

  2004cites this paper
• Molecular basis of two novel dehalogenating activities in bacteria

  2004cites this paper
• Regulation of cell fate by phosphorylation : a tale of two transcription factors

  2004cites this paper
• Lys691 and Asp714 of the Na+/K+-ATPase alpha subunit are essential for phosphorylation, dephosphorylation, and enzyme turnover.

  2004cites this paper
• gob-1 is a trehalose-6-phosphate phosphatase required for intestine development in the nematode caenorhabditis elegans

  2004cites this paper
• Introducing Wilson disease mutations into ZntA : Studies on the nucleotide and metal-binding sites of a bacterial zinc-translocating P-type ATPase

  2004cites this paper
• FITC binding site and p-nitrophenyl phosphatase activity of the Kdp-ATPase of Escherichia coli.

  2004cites this paper
• Structure and mechanism of Na,K-ATPase: functional sites and their interactions.

  2003cites this paper
• Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily.

  2003cites this paper
• Thermophile-specific proteins: the gene product of aq_1292 from Aquifex aeolicus is an NTPase

  2003cites this paper
• The transcription factor Eyes absent is a protein tyrosine phosphatase

  2003cites this paper
• Eyes absent represents a class of protein tyrosine phosphatases

  2003cites this paper
• Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond.

  2003cites this paper
• Dissection of the Functional Differences between Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA) 1 and 2 Isoforms and Characterization of Darier Disease (SERCA2) Mutants by Steady-state and Transient Kinetic Analyses*

  2003cites this paper
• Molecular Architecture of the Phosphorylation Region of the Yeast Plasma Membrane H+-ATPase*

  2003cites this paper
• Mg2+ sensing by the Mg2+ sensor PhoQ of Salmonella enterica.

  2003cites this paper
• Escherichia coli YrbI Is 3-Deoxy-d-manno-octulosonate 8-Phosphate Phosphatase*

  2003cites this paper
• Mechanism of phosphatase activity in the chemotaxis response regulator CheY.

  2003cites this paper
• Intramolecular rearrangements as a consequence of the dephosphorylation of phosphoaspartate residues in proteins

  2003cites this paper
• High-resolution structure of human phosphoserine phosphatase in open conformation.

  2003cites this paper
• Molecular Evolution of Histidine Kinases

  2003cites this paper
• Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short‐chain dehydrogenase/reductase fold without an NAD(P)H binding site

  2003cites this paper
• Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13.

  2002cites this paper
• Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.

  2002cites this paper
• Information Processing in Bacterial Chemotaxis

  2002cites this paper
• Caught in the Act : The Structure of Phosphorylated â-Phosphoglucomutase from Lactococcus lactis

  2002influential citation
• Nucleotide Binding to Na,K-ATPase: The Role of Electrostatic Interactions.

  2002cites this paper
• Introducing Wilson disease mutations into the zinc-transporting P-type ATPase of Escherichia coli. The mutation P634L in the 'hinge' motif (GDGXNDXP) perturbs the formation of the E2P state.

  2002cites this paper
• Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.

  2002cites this paper
• Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis.

  2002cites this paper
• Molecular Basis for the Local Conformational Rearrangement of Human Phosphoserine Phosphatase*

  2002cites this paper
• The ATP-Mg2+ binding site and cytoplasmic domain interactions of Na+,K+-ATPase investigated with Fe2+-catalyzed oxidative cleavage and molecular modeling.

  2002cites this paper
• Importance of Thr-353 of the Conserved Phosphorylation Loop of the Sarcoplasmic Reticulum Ca2+-ATPase in MgATP Binding and Catalytic Activity*

  2001cites this paper
• BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.

  2001cites this paper
• Selective Fe2+-catalyzed Oxidative Cleavage of Gastric H+,K+-ATPase

  2001cites this paper
• PLANT PLASMA MEMBRANE H+-ATPases: Powerhouses for Nutrient Uptake.

  2001cites this paper
• Phosphoaspartates in bacterial signal transduction.

  2001cites this paper