Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Molecular human reproduction

• Publication date

  2012-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/molehr/gas014PMID 22447119
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Assisted reproduction treatment and epigenetic inheritance

  2012cited by this paper
• Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

  2012cited by this paper
• Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos

  2011cited by this paper
• Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

  2011cited by this paper
• Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

  2011cited by this paper
• Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.

  2011cited by this paper
• Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

  2011cited by this paper
• In brief

  2011cited by this paper
• Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

  2011cited by this paper
• Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine

  2011cited by this paper
• Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

  2011cited by this paper
• Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

  2011cited by this paper
• Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

  2011cited by this paper
• Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.

  2011cited by this paper
• The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

  2011cited by this paper
• 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.

  2011influential reference
• Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells

  2011cited by this paper
• Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

  2011cited by this paper
• Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development

  2011cited by this paper
• Reprogramming towards pluripotency requires AID-dependent DNA demethylation

  2010cited by this paper
• The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

  2010cited by this paper
• Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

  2010cited by this paper
• Epigenetic characteristics of paternal chromatin in interspecies zygotes.

  2010cited by this paper
• Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

  2010cited by this paper
• Cytidine deaminases: AIDing DNA demethylation?

  2010cited by this paper
• A role for elongator in zygotic paternal genome demethylation

  2010cited by this paper
• Active loss of DNA methylation in two-cell stage goat embryos.

  2010cited by this paper
• Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

  2010cited by this paper
• Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

  2010cited by this paper
• Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes

  2009cited by this paper
• Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

  2009cited by this paper
• Epigenetic reprogramming and induced pluripotency

  2009cited by this paper
• Impaired active demethylation of the paternal genome in pronuclear‐stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection

  2009cited by this paper
• Functional Analysis of Male Mouse Haploid Germ Cells of Various Differentiation Stages: Early and Late Round Spermatids Are Functionally Equivalent in Producing Progeny1

  2009cited by this paper
• Demethylation dynamics of the paternal genome in pronuclear-stage bovine zygotes produced by in vitro fertilization and ooplasmic injection of freeze-thawed or freeze-dried spermatozoa.

  2009cited by this paper
• DNA demethylation in hormone-induced transcriptional derepression

  2009cited by this paper
• Cyclical DNA methylation of a transcriptionally active promoter

  2008influential reference
• Transient cyclical methylation of promoter DNA

  2008cited by this paper
• Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1

  2008cited by this paper
• Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

  2008cited by this paper
• Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes.

  2008cited by this paper
• Hypomethylation of paternal DNA in the late mouse zygote is not essential for development.

  2008cited by this paper
• Suboptimal in vitro culture conditions: an epigenetic origin of long‐term health effects

  2007cited by this paper
• Epigenetic Marks in Cloned Rhesus Monkey Embryos: Comparison with Counterparts Produced In Vitro1

  2007cited by this paper
• Dynamics of DNA‐demethylation in early mouse and rat embryos developed in vivo and in vitro

  2007cited by this paper
• PGC7/Stella protects against DNA demethylation in early embryogenesis

  2007cited by this paper
• DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote.

  2007cited by this paper
• Dynamic DNA methylation reprogramming: Active demethylation and immediate remethylation in the male pronucleus of bovine zygotes

  2007cited by this paper
• DNA methylation pattern in pig in vivo produced embryos

  2006cited by this paper
• Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids.

  2006cited by this paper
• No differences in the DNA methylation pattern in mouse zygotes produced in vivo, in vitro, or by intracytoplasmic sperm injection.

  2006cited by this paper
• DNA methylation pattern in pig in vivo produced embryos

  2006cited by this paper
• C → T mutagenesis and γ‐radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases

  2005cited by this paper
• The capability of reprogramming the male chromatin after fertilization is dependent on the quality of oocyte maturation.

  2005cited by this paper
• DNA methylation pattern in human zygotes and developing embryos.

  2004cited by this paper
• DNA methylation patterns in human tripronucleate zygotes.

  2004cited by this paper
• The effect of interspecific oocytes on demethylation of sperm DNA.

  2004cited by this paper
• Non-conservation of mammalian preimplantation methylation dynamics.

  2004cited by this paper
• Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.

  2003cited by this paper
• Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

  2003cited by this paper
• Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient Mice

  2002cited by this paper
• Aberrant methylation patterns at the two‐cell stage as an indicator of early developmental failure

  2002cited by this paper
• Epigenetic reprogramming in mouse primordial germ cells.

  2002cited by this paper
• DNA methylation patterns and epigenetic memory.

  2002cited by this paper
• Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.

  2002cited by this paper
• Dynamic reprogramming of DNA methylation in the early mouse embryo.

  2002cited by this paper
• Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos

  2001influential reference
• Genome-wide methylation patterns in normal and uniparental early mouse embryos.

  2001cited by this paper
• Embryogenesis: Demethylation of the zygotic paternal genome

  2000cited by this paper
• Demethylation of the zygotic paternal genome.

  2000cited by this paper
• Active demethylation of the paternal genome in the mouse zygote.

  2000cited by this paper
• Mitochondria and the death of oocytes

  2000cited by this paper
• Chromosome methylation patterns during mammalian preimplantation development.

  1998cited by this paper
• Primordial germ cells

  1980cited by this paper

• The Synchronized Progression from Mitosis to Meiosis in Female Primordial Germ Cells between Layers and Broilers

  2023cites this paper
• Constant light exposure causes oocyte meiotic defects and quality deterioration in mice.

  2020cites this paper
• Melatonin prevents deterioration in quality by preserving epigenetic modifications of porcine oocytes after prolonged culture

  2018cites this paper
• Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss

  2018cites this paper
• Oviduct: roles in fertilization and early embryo development.

  2017cites this paper
• Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch.

  2017cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Epigenetic imprinting during assisted reproductive technologies: The effect of temporal and cumulative fluctuations in methionine cycling on the DNA methylation state

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct : roles in fertilization and early embryo development

  2016cites this paper
• Oviduct : roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct : roles in fertilization and early embryo development

  2016cites this paper
• Oviduct : roles in fertilization and early embryo development

  2016cites this paper
• Oviduct: roles in fertilization and early embryo development

  2016cites this paper
• Oviduct : roles in fertilization and early embryo development

  2016cites this paper
• Epigenetic processes in the male germline.

  2015cites this paper
• Exogenous thymine DNA glycosylase regulates epigenetic modifications and meiotic cell cycle progression of mouse oocytes.

  2015cites this paper
• Pluripotency in the light of the developmental hourglass

  2015cites this paper
• DNA methylation and its role in the trophoblast cell lineage.

  2014cites this paper
• Dynamic regulation of DNA methyltransferases in human oocytes and preimplantation embryos after assisted reproductive technologies.

  2014cites this paper
• Oocyte ageing and epigenetics

  2014cites this paper
• Embryo transcriptome response to environmental factors: implication for its survival under suboptimal conditions.

  2014cites this paper
• Abnormal lysine acetylation with postovulatory oocyte aging

  2014cites this paper
• Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome

  2014influential citation
• The root of reduced fertility in aged women and possible therapentic options: current status and future perspects.

  2014cites this paper
• Epigenetic effects on the embryo as a result of periconceptional environment and assisted reproduction technology.

  2013cites this paper
• The presence, role and clinical use of spermatozoal RNAs.

  2013cites this paper
• The role of promoter hypermethylation in fibroblast activation and fibrogenesis

  2013cites this paper
• Superovulation induces defective methylation in line-1 retrotransposon elements in blastocyst

  2013cites this paper
• Epigenetic changes associated with oocyte aging

  2012cites this paper
• DNA Methylation Regulates Human Endometrial Stromal Cell Decidualisation

  2012cites this paper
• A methodological overview on molecular preimplantation genetic diagnosis and screening: a genomic future?

  2012cites this paper