Comparative outcomes study of metformin intervention versus conventional approach the COSMIC Approach Study.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Diabetes Care

• Publication date

  2005-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2337/DIACARE.28.3.539PMID 15735184
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysis.

  2003cited by this paper
• Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.

  2003cited by this paper
• Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.

  2002cited by this paper
• Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

  2002cited by this paper
• Lactic Acidosis in Metformin-Treated Patients

  1999cited by this paper
• The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.

  1999cited by this paper
• Lactic acidosis in metformin-treated patients. Prognostic value of arterial lactate levels and plasma metformin concentrations.

  1999cited by this paper
• Phenformin and lactic acidosis: a case report and review.

  1998cited by this paper
• Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

  1998cited by this paper
• Lactic acidosis in patients with diabetes treated with metformin.

  1998cited by this paper
• Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

  1998cited by this paper
• Lactic Acidosis Rates in Type 2 Diabetes

  1998cited by this paper
• Natural history and course of acquired lactic acidosis in adults. DCA-Lactic Acidosis Study Group.

  1994cited by this paper
• Comparative Tolerability Profiles of Oral Antidiabetic Agents

  1994cited by this paper
• Re-evaluation of a biguanide, metformin: mechanism of action and tolerability.

  1994cited by this paper
• Natural history and course of acquired lactic acidosis in adults

  1994cited by this paper
• Phenformin-Induced Lactic Acidosis: A Forgotten Adverse Drug Reaction

  1993cited by this paper
• Biguanides and NIDDM

  1992cited by this paper
• Biguanide related lactic acidosis: incidence and risk factors.

  1992cited by this paper
• The hyperlactatemic effect of biguanides: a comparison between phenformin and metformin during a 6-month treatment.

  1989cited by this paper
• Treatment of lactic acidosis with dichloroacetate.

  1983cited by this paper
• Phenformin-associated lactic acidosis: pathogenesis and treatment.

  1977cited by this paper
• Hyperlactatemia.

  1970cited by this paper

• Risk of medication-induced lactic acidosis and hyperlactatemia: a pharmacovigilance study of the United States Food and Drug Administration’s Adverse Event Reporting System database

  2025cites this paper
• Impact of Diabetes and Metformin on Cardiovascular Outcomes in Prostate Cancer Patients Aged 66 and Older: The Role of Social Determinants of Health and Racial Disparities

  2025cites this paper
• The Effect of Metformin on some Physiological Traits in Rats with Alloxan-Induced Diabetes

  2024cites this paper
• Metformin exposure and the incidence of lactic acidosis in critically ill patients with T2DM: A retrospective cohort study

  2024cites this paper
• [Non-Insulin Antidiabetic Agents in the Management of Hyperglycaemia of Non-Critical Hospitalized Patients].

  2024cites this paper
• Impact of metformin on cardiovascular and kidney outcome based on kidney function status in type 2 diabetic patients: a multicentric, retrospective cohort study

  2024cites this paper
• Challenges in developing Geroscience trials

  2023cites this paper
• Reversible acute blindness in suspected metformin-associated lactic acidosis: a case report

  2023cites this paper
• Can metformin use reduce the risk of stroke in diabetic patients? A systematic review and meta-analysis.

  2023cites this paper
• [Metformin use and risk of ischemic stroke in patients with type 2 diabetes: A cohort study].

  2023cites this paper
• Diabetes and Kidney disease: metformin

  2022cites this paper
• Metformin: A Narrative Review of Its Potential Benefits for Cardiovascular Disease, Cancer and Dementia

  2022cites this paper
• Geroscience‐guided repurposing of FDA‐approved drugs to target aging: A proposed process and prioritization

  2022cites this paper
• Undercover Toxic Ménage à Trois of Amylin, Copper (II) and Metformin in Human Embryonic Kidney Cells

  2021cites this paper
• Metformin and Lactic Acidosis in Diabetic Patients

  2021cites this paper
• Metformin ameliorates the severity of experimental Alport syndrome

  2021cites this paper
• Cardiovascular Effects of Hypoglycemic Agents in Diabetes Mellitus.

  2020cites this paper
• Metformin and cardiorenal outcomes in diabetes: A reappraisal

  2020cites this paper
• Metformin induced acute kidney injury; a systematic review

  2020cites this paper
• Features of postoperative therapy in patients with type ІІ diabetes

  2020cites this paper
• Assessing Drug Safety Assessment: Metformin Associated Lactic Acidosis

  2020cites this paper
• Effect of continuous use of metformin on kidney function in diabetes patients with acute myocardial infarction undergoing primary percutaneous coronary intervention

  2020cites this paper
• Evaluating the effectiveness of a support programme for people with type 2 diabetes mellitus in primary care: an observational prospective study in Ecuador

  2020cites this paper
• Hospitalization for Lactic Acidosis Among Patients With Reduced Kidney Function Treated With Metformin or Sulfonylureas

  2020cites this paper
• Stroke in the patient with diabetes (Part 2) -Prevention and the effects of glucose lowering therapies.

  2020cites this paper
• Diabetes and Metabolism

  2020cites this paper
• Where Does Metformin Stand in Modern Day Management of Type 2 Diabetes?

  2020cites this paper
• GLUcose COntrol Safety & Efficacy in type 2 DIabetes, a systematic review and NETwork meta-analysis

  2019cites this paper
• Metformin Use and Metformin-associated Lactic Acidosis in Intensive Care Unit Patients with Diabetes

  2019cites this paper
• The “Old” Oral Antidiabetics

  2019cites this paper
• Reversible Acute Blindness in Suspected Metformin-Associated Lactic Acidosis.

  2019cites this paper
• Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus.

  2019cites this paper
• Intravenous contrast agents in diabetic patients taking metformin; an updated review on current concepts

  2019cites this paper
• Metformin Contributed with Lactic Acidosis in The White Male Rats

  2019cites this paper
• Cardioprotection by Metformin: Beneficial Effects Beyond Glucose Reduction

  2018cites this paper
• Metformin monotherapy for adults with type 2 diabetes mellitus.

  2018cites this paper
• Therapy to Obese Type 2 Diabetes Mellitus: How Far Will We Go Down the Wrong Road?

  2018cites this paper
• METFORMIN THERAPY FOR PREDIABETES

  2018cites this paper
• Assessing the incidence of acidosis in patients receiving metformin with and without risk factors for lactic acidosis

  2018cites this paper
• Antidiabetics' usage in type 2 diabetes mellitus: Are prescribing guidelines adhered to? A single centre study.

  2018cites this paper
• Is it necessary to discontinue metformin in diabetic patients with GFR > 60 ml/min per 1.73 m2 undergoing coronary angiography: A controversy still exists?

  2018cites this paper
• Drug Effects and Clinical Investigations for Contrast-Induced Nephropathy After Coronary Angiography or Percutaneous Coronary Intervention in Patients With Diabetes

  2017cites this paper
• Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes

  2017influential citation
• Metformin Use in Children and Adolescents with Prediabetes.

  2017cites this paper
• Berberine protects against metformin-associated lactic acidosis in induced diabetes mellitus

  2017cites this paper
• Efficacy and safety of metformin in the management of type 2 diabetes mellitus in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing

  2017influential citation
• Protocol for a pilot randomised controlled trial of metformin in pre-diabetes after kidney transplantation: the Transplantation and Diabetes (Transdiab) study

  2017cites this paper
• Nephroprotective Effects of Metformin in Diabetic Nephropathy

  2017cites this paper
• Safety of Metformin Therapy in Patients with Type 2 Diabetes Living on an Oxygen-Deficient Plateau, Tibet, China.

  2017cites this paper
• Impact of glucose-lowering therapies on risk of stroke in type 2 diabetes.

  2017cites this paper
• Provider Decisions and Patient Outcomes After Premature Metformin Discontinuation

  2017cites this paper
• Metformin and Intravascular Contrast Media: What to do in Patients Receiving Both: a Narrative Review

  2017cites this paper
• Metformin: From Research to Clinical Practice.

  2016cites this paper
• Metformin – A Mini Review

  2016cites this paper
• Retrospective analysis of lactic acidosis-related parameters upon and after metformin discontinuation in patients with diabetes and chronic kidney disease

  2016cites this paper
• Prescribing attitudes, behaviors and opinions regarding metformin for patients with diabetes: a focus group study

  2016cites this paper
• Metformin-associated lactic acidosis: Current perspectives on causes and risk.

  2016cites this paper
• Metformin in advanced chronic kidney disease: are current guidelines overly restrictive?

  2016cites this paper
• Metformin-related lactic acidosis: is it a myth or an underestimated reality?

  2016cites this paper
• Usage of metformin in patients with type 2 diabetes mellitus

  2016cites this paper
• Cardiovascular safety of anti-diabetic drugs.

  2016cites this paper
• Insulinosensibilisateurs (metformine/glitazones) : niveau de preuve et controverse

  2015cites this paper
• Metformininduzierte Laktatacidose

  2015cites this paper
• Metformin-Associated Lactic Acidosis

  2015cites this paper
• Metformin-Associated Lactic Acidosis: Predisposing Factors and Outcome

  2015cites this paper
• Therapeutic Use of Metformin in Prediabetes and Diabetes Prevention

  2015cites this paper
• Glucose-lowering drugs or strategies and cardiovascular outcomes in patients with or at risk for type 2 diabetes: a meta-analysis of randomised controlled trials.

  2015cites this paper
• Metformin-associated lactic acidosis.

  2015cites this paper
• Anti-diabetic Effects of Barnyard Millet Miryang 3 [Echinochloa esculenta (A. Braun)] Grains on Blood Glucose in C57BL/KsJ-db/db Mice

  2015cites this paper
• Metformin: A Drug of Choice for Gestational Diabetes Mellitus in Near Future- Hope or Despair?

  2015cites this paper
• Saxagliptin and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Moderate or Severe Renal Impairment: Observations From the SAVOR-TIMI 53 Trial

  2014cites this paper
• Chapitre 24 – Thérapeutiques antidiabétiques

  2014cites this paper
• Pharmacotherapy for Hyperglycemia in Noncritically Ill Hospitalized Patients

  2014cites this paper
• Metformin usage in type 2 diabetes mellitus: are safety guidelines adhered to?

  2014cites this paper
• Metformin-associated lactic acidosis presenting as an ischemic gut in a patient who then survived a cardiac arrest: a case report

  2014cites this paper
• Saxagliptin and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Moderate or Severe Renal Impairment: Observations From the SAVOR-TIMI 53 Trial

  2014cites this paper
• ANTI-INSULIN RESISTANCE TREATMENTS SUPPRESS HER2+ BREAST CANCER GROWTH VIA ALTERING METABOLISM

  2014cites this paper
• MALAdaptive: Do We Avoid Metformin Unnecessarily?

  2014cites this paper
• Comparative efficacy of glimepiride and metformin in monotherapy of type 2 diabetes mellitus: meta-analysis of randomized controlled trials

  2013cites this paper
• Lactic acidosis in patients with diabetes.

  2013cites this paper
• Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass

  2013cites this paper
• Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

  2013cites this paper
• Results of a reevaluation of cardiovascular outcomes in the RECORD trial.

  2013cites this paper
• Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials

  2012cites this paper
• Lactic acidosis in medical ICU - the role of diabetes mellitus and metformin.

  2012cites this paper
• Discontinuation of metformin in the setting of coronary angiography: clinical uncertainty amongst physicians reflecting a poor evidence base.

  2012cites this paper
• Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials

  2012cites this paper
• Comparative Effectiveness of Sulfonylurea and Metformin Monotherapy on Cardiovascular Events in Type 2 Diabetes Mellitus

  2012cites this paper
• Erratum to: Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials

  2012influential citation
• Inappropriate metformin prescribing in elderly type 2 diabetes mellitus (T2DM) patients.

  2012cites this paper
• Shift From Surrogate End Point to Outcome Trials: Implications for Cardiovascular Safety Assessment in Development Programs for Antidiabetic Drugs

  2012cites this paper
• Reappraisal of metformin ecacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials.

  2012cites this paper
• Mortality Rates in Trials of Subjects With Type 2 Diabetes

  2012cites this paper
• [Metformin - mechanisms of action and use for the treatment of type 2 diabetes mellitus].

  2011cites this paper
• Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines

  2011cites this paper
• Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.

  2011cites this paper
• Is the Large Simple Trial Design Used for Comparative, Post-Approval Safety Research?

  2011cites this paper
• Diabetes, metformin and lactic acidosis

  2011cites this paper
• Chapitre 39 - Pharmacologie et Thérapeutique Vasculaire

  2011cites this paper
• Urgences métaboliques du diabète sucré

  2011cites this paper