Is tumor growth sustained by rare cancer stem cells or dominant clones?

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cancer Research

• Publication date

  2008-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-07-6334PMID 18519656
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isolation and Molecular Characterization of Cancer Stem Cells in MMTV‐Wnt‐1 Murine Breast Tumors

  2008cited by this paper
• Leukemia stem cells in a genetically defined murine model of blast-crisis CML.

  2007cited by this paper
• Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia.

  2007cited by this paper
• Identification and expansion of human colon-cancer-initiating cells

  2007cited by this paper
• Identification of stem cells in small intestine and colon by marker gene Lgr5

  2007cited by this paper
• Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells

  2007cited by this paper
• "Destemming" cancer stem cells.

  2007cited by this paper
• Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell.

  2007cited by this paper
• A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

  2007cited by this paper
• Breast Tumor Heterogeneity: Cancer Stem Cells or Clonal Evolution?

  2007cited by this paper
• Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

  2006cited by this paper
• Identifying cancer stem cells in solid tumors: case not proven.

  2006cited by this paper
• Generation of a functional mammary gland from a single stem cell

  2006cited by this paper
• Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

  2006cited by this paper
• Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

  2006cited by this paper
• AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML.

  2006cited by this paper
• Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

  2006cited by this paper
• Targeting of CD44 eradicates human acute myeloid leukemic stem cells

  2006cited by this paper
• Cancer stem cells.

  2006cited by this paper
• Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

  2006cited by this paper
• Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.

  2006cited by this paper
• CD133+ renal progenitor cells contribute to tumor angiogenesis.

  2006cited by this paper
• Targeted CML therapy: controlling drug resistance, seeking cure.

  2006cited by this paper
• Cancer stem cells: lessons from leukemia.

  2005influential reference
• Identification of human brain tumour initiating cells

  2004cited by this paper
• Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.

  2004cited by this paper
• MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

  2004cited by this paper
• Prospective identification of tumorigenic breast cancer cells

  2003cited by this paper
• Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

  2003cited by this paper
• Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

  1997cited by this paper
• Cytokines: coordinators of immune and inflammatory responses.

  1990cited by this paper
• A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin.

  1976cited by this paper
• The Transmission of Leukemia of Mice with a Single Cell

  1937cited by this paper

• Targeted Delivery of Chlorin-e6-Loaded Carbon Nanotube-Based Nanobiocomposite to Cancer Stem Cells for Enhanced Photodynamic Therapy

  2025cites this paper
• Metabolic adaptations in cancer stem cells: A key to therapy resistance.

  2024cites this paper
• Mitochondrial–Stem Cell Connection: Providing Additional Explanations for Understanding Cancer

  2024cites this paper
• DLK1 Is Associated with Stemness Phenotype in Medullary Thyroid Carcinoma Cell Lines

  2024cites this paper
• The Role of HDAC6 in Glioblastoma Multiforme: A New Avenue to Therapeutic Interventions?

  2024cites this paper
• Sniping Cancer Stem Cells with Nanomaterials.

  2023cites this paper
• Targeting liver cancer stem cell through EpCAM therapy targeted with chemotherapy endorse enhanced progression in hepatocellular carcinoma

  2023cites this paper
• The “Superoncogene” Myc at the Crossroad between Metabolism and Gene Expression in Glioblastoma Multiforme

  2023cites this paper
• Potential to Eradicate Cancer Stemness by Targeting Cell Surface GRP78

  2022cites this paper
• Harnessing non-destructive 3D pathology

  2021cites this paper
• Strategic Development of an Immunotoxin for the Treatment of Glioblastoma and Other Tumours Expressing the Calcitonin Receptor

  2021cites this paper
• Cancer Stem Cells: Metabolic Characterization for Targeted Cancer Therapy

  2021cites this paper
• Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6

  2021cites this paper
• The Renin–Angiotensin System in the Tumor Microenvironment of Glioblastoma

  2021cites this paper
• BRAT1 depletion impairs DNA damage repair in glioblastoma cell lines

  2021cites this paper
• INTERNATIONAL JOURNAL OF NOVEL TRENDS IN PHARMACEUTICAL SCIENCES

  2020cites this paper
• Autophagy induced by Helicobacter pylori infection is necessary for gastric cancer stem cell emergence

  2020cites this paper
• Energy metabolism in cancer stem cells.

  2020cites this paper
• Adenylate Kinase and Metabolic Signaling in Cancer Cells

  2020cites this paper
• Embryonic stem cell-like subpopulations are present within Schwannoma.

  2020cites this paper
• Crosstalk Between Prostate Cancer Stem Cells and Immune Cells: Implications for Tumor Progression and Resistance to Immunotherapy

  2019cites this paper
• STUDY OF JADOMYCIN PHARMACOKINETICS AND ANTI-BREAST CANCER ACTIVITY IN BALB/C MICE

  2019cites this paper
• Role of Notch Signaling Pathway in Glioblastoma Pathogenesis

  2019cites this paper
• Emergent Properties of a Computational Model of Tumour Growth 2

  2019cites this paper
• Utility of macrophages in an antitumor strategy based on the vectorization of iron oxide nanoparticles.

  2019cites this paper
• A Cancer Stem Cell Perspective on Minimal Residual Disease in Solid Malignancies

  2019cites this paper
• Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells.

  2019cites this paper
• Tumour stem cells in schwannoma: A review.

  2019cites this paper
• NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis

  2019cites this paper
• UNDERSTANDING THE MECHANISM OF DRUG-RESISTANT AND TUMOR RECURRENCE IN LIVER CANCER

  2018cites this paper
• Cancer stem cells modulate patterns and processes of evolution in cancers

  2018cites this paper
• Cancer stem cells modulate patterns and processes of evolution in cancers

  2018cites this paper
• Emerging Therapies in the Management of Advanced-Stage Gastric Cancer

  2018cites this paper
• Genetics and Expression Profile of the Tubulin Gene Superfamily in Breast Cancer Subtypes and Its Relation to Taxane Resistance

  2018cites this paper
• Targeting Nodal and Cripto-1: perspectives inside dual potential theranostic cancer biomarkers.

  2018cites this paper
• Polyene phosphatidylcholine overcomes oxaliplatin resistance in human gastric cancer BGC823 cells.

  2018cites this paper
• Cancer Stem Cells, Bone and Tumor Microenvironment: Key Players in Bone Metastases

  2018cites this paper
• Antipsychotic dopamine receptor antagonists, cancer, and cancer stem cells

  2018cites this paper
• Bioenergetics of acquired cisplatin resistant H1299 non-small cell lung cancer and P31 mesothelioma cells

  2017cites this paper
• Identifying and targeting cancer stem cells in the treatment of gastric cancer

  2017influential citation
• Kinase Inhibitors in Multitargeted Cancer Therapy.

  2017cites this paper
• IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status

  2017cites this paper
• Chapter 3 Tumor Microenvironment — Perivascular and Perinecrotic Niches

  2017cites this paper
• Drug-Loaded Polymeric Nanoparticles for Cancer Stem Cell Targeting

  2017cites this paper
• Renin-angiotensin system and cancer: A review

  2017cites this paper
• Role of epigenetic modulation in cancer stem cell fate.

  2017cites this paper
• Expression profiles of cancer stem cell markers: CD133, CD44, Musashi-1 and EpCAM in the cardiac mucosa-Barrett's esophagus-early esophageal adenocarcinoma-advanced esophageal adenocarcinoma sequence.

  2017cites this paper
• Cancer stem cells: A product of clonal evolution?

  2017cites this paper
• Metformin targets gastric cancer stem cells.

  2017cites this paper
• 2 Stem Cells and Mesothelioma

  2017cites this paper
• Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines

  2017cites this paper
• Identification and Phenotypic Plasticity of Metastatic Cells in a Mouse Model of Melanoma

  2017cites this paper
• The Functions of EP300 in Activated Pancreatic Stellate Cells and the Drug Resistance Problem in Pancreatic Cancer

  2017cites this paper
• Minimal residual disease in breast cancer: an overview of circulating and disseminated tumour cells

  2016influential citation
• Cancer Stem Cell Hierarchy in Glioblastoma Multiforme

  2016influential citation
• Nanotechnology for cancer therapy

  2016cites this paper
• Cancer Stem Cells — Perspectives and How to Target Them

  2016cites this paper
• Transcriptional networks controlled by SOX2 in glioblastoma stem cells

  2016cites this paper
• Cancer stem cell metabolism: a potential target for cancer therapy

  2016cites this paper
• The Epithelial-to-Mesenchymal Transition Regulates the E-selectin Ligand Activities of Breast Cancer Cells

  2016cites this paper
• Drug resistance in cancer: molecular evolution and compensatory proliferation

  2016cites this paper
• Emergent properties of a computational model of tumour growth

  2016cites this paper
• Cancer Stem Cells in Glioblastoma Multiforme

  2016cites this paper
• Discovery of Power-Law Growth in the Self-Renewal of Heterogeneous Glioma Stem Cell Populations

  2015cites this paper
• Cancer Stem Cells: Plasticity Works against Therapy

  2015cites this paper
• CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells

  2015cites this paper
• Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia

  2015cites this paper
• Transient expression of Bcl 6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

  2015cites this paper
• Iron metabolism: a double-edged sword in the resistance of glioblastoma to therapies.

  2015cites this paper
• Candidate therapeutic targets against acute myeloid leukemia identified via screening combinatorial peptide and chemical libraries

  2015cites this paper
• CD20 Antibody-Conjugated Immunoliposomes for Targeted Chemotherapy of Melanoma Cancer Initiating Cells.

  2015cites this paper
• Active Targeting of Nano-Photosensitizer Delivery Systems for Photodynamic Therapy of Cancer Stem Cells.

  2015cites this paper
• Nanomedicine to overcome radioresistance in glioblastoma stem-like cells and surviving clones.

  2015cites this paper
• Tumor Microenvironment — Perivascular and Perinecrotic Niches

  2015cites this paper
• The first five years of single-cell cancer genomics and beyond

  2015cites this paper
• Cancer stem cells in solid and liquid tissues of breast cancer patients: characterization and therapeutic perspectives.

  2015cites this paper
• Emergent properties of a non-physiological computational model of tumour growth

  2015cites this paper
• Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

  2014cites this paper
• Highly Multiplexed Phenotypic Imaging for Cell Proliferation Studies

  2014cites this paper
• Coencapsulation of epirubicin and metformin in PEGylated liposomes inhibits the recurrence of murine sarcoma S180 existing CD133+ cancer stem-like cells.

  2014cites this paper
• DiSWOP: a novel measure for cell-level protein network analysis in localized proteomics image data

  2014cites this paper
• Implication de réseaux de récepteurs membranaires dans la signalisation du NGF et de son précurseur dans les cellules cancéreuses de sein

  2014cites this paper
• Développement de nouveaux vecteurs de radiothérapie interne pour le ciblage des cellules cancéreuses de type souche dans le glioblastome

  2014cites this paper
• Spatial Relationships of MR Imaging and Positron Emission Tomography with Phenotype, Genotype and Tumor Stem Cell Generation in Glioblastoma Multiforme

  2014cites this paper
• Difficulties in Targeting the Beating Heart

  2014cites this paper
• Cancer genomics: one cell at a time

  2014cites this paper
• Targeting cancer stem cells by curcumin and clinical applications.

  2014cites this paper
• On the dynamics of neutral mutations in a mathematical model for a homogeneous stem cell population

  2013cites this paper
• Eradication of therapy-resistant cancer cells in gastrointestinal organs.

  2013cites this paper
• Colon cancer heterogeneity: Stem cells, signals and subtypes

  2013cites this paper
• Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts.

  2013cites this paper
• PAX3 expression, protein modifications and downstream target gene profiling in melanocytes and melanoma cells

  2013cites this paper
• Synergistic enhancement of cancer therapy using a combination of heat shock protein targeted HPMA copolymer-drug conjugates and gold nanorod induced hyperthermia.

  2013cites this paper
• Heterogeneity and Plasticity of Multiple Myeloma

  2013cites this paper
• Recruitment of Normal Stem Cells to an Oncogenic Phenotype by Noncontiguous Carcinogen-Transformed Epithelia Depends on the Transforming Carcinogen

  2013cites this paper
• Epithelial-to-mesenchymal transition and cancer stem(-like) cells in head and neck squamous cell carcinoma.

  2013cites this paper
• Role of integrated cancer nanomedicine in overcoming drug resistance.

  2013cites this paper
• Tumor Cells Positive and Negative for the Common Cancer Stem Cell Markers Are Capable of Initiating Tumor Growth and Generating Both Progenies

  2013cites this paper
• Allgemeine Grundlagen der Tumorbiologie in der Viszeralchirurgie

  2013cites this paper
• Phylogenetic Quantification of Intra-tumour Heterogeneity

  2013cites this paper