Assessment of endostatin gene therapy for familial adenomatous polyposis-related desmoid tumors.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cancer Research

• Publication date

  2006-08-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-06-1209PMID 16912203
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996cited by this paper
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