The natural history of primary lateral sclerosis

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Neurology

• Publication date

  2006-03-14

• Fields of study

  Medicine

• Identifiers
  DOI 10.1212/01.wnl.0000200962.94777.71PMID 16534101
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Primary lateral sclerosis, hereditary spastic paraplegia, and mutations in the alsin gene: Historical background for the first International Conference

  2005cited by this paper
• The Pathology of Amyotrophic Lateral Sclerosis

  2005cited by this paper
• Primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral sclerosis: Discrete entities or spectrum?

  2005cited by this paper
• Lewy body-like hyaline inclusions in sporadic motor neuron disease are ubiquitinated

  2004cited by this paper
• Frontotemporal dementia with ubiquitinated neuronal inclusions presenting with primary lateral sclerosis and parkinsonism: clinicopathological report of an autopsy case

  2004cited by this paper
• Primary lateral sclerosis

  2003cited by this paper
• Primary lateral sclerosis: a rare upper-motor-predominant form of amyotrophic lateral sclerosis often accompanied by frontotemporal lobar degeneration with ubiquitinated neuronal inclusions?

  2003cited by this paper
• Does primary lateral sclerosis exist? A study of 20 patients and a review of the literature.

  2001cited by this paper
• Primary lateral sclerosis: clinical, neurophysiological, and magnetic resonance findings

  2001cited by this paper
• Primary lateral sclerosis: further clarification.

  2001cited by this paper
• El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis

  2000cited by this paper
• A case of primary lateral sclerosis taking a prolonged clinical course with dementia and having an unusual dendritic ballooning

  1999cited by this paper
• The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III).

  1999cited by this paper
• Upper motor neuron predominant degeneration with frontal and temporal lobe atrophy

  1998cited by this paper
• Motor neuron syndromes in cancer patients

  1997cited by this paper
• [Chronic progressive spinobulbar spasticity (primary lateral sclerosis)].

  1996cited by this paper
• Die chronisch-progrediente spinobulbäre Spastik (primäre Lateralsklerose)

  1996cited by this paper
• Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis.

  1995cited by this paper
• Primary lateral sclerosis

  1995cited by this paper
• Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria.

  1992cited by this paper
• A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin.

  1988cited by this paper
• Primary lateral sclerosis. A clinical diagnosis reemerges.

  1988cited by this paper
• Ubiquitin deposits in anterior horn cells in motor neurone disease.

  1988cited by this paper
• Pathology of amyotrophic lateral sclerosis.

  1982cited by this paper
• Primary Lateral Sclerosis: A Case Report

  1981cited by this paper
• Primary lateral sclerosis: a case report.

  1981cited by this paper
• Pure Spastic Paralysis of Corticospinal Origin

  1977cited by this paper
• Anterior horn cell degeneration and Bunina-type inclusions associated with dementia

  1977cited by this paper
• The central nervous system in motor neurone disease

  1970cited by this paper
• On intracellular inclusions in familial amyotrophic lateral sclerosis

  1962cited by this paper
• Spastic and Syphilitic Spinal Paralysis

  1902cited by this paper
• Concerning Spastic and Syphilitic Spinal Paralysis *

  1902cited by this paper

• Demographic, clinical and genetic characteristics of patients with amyotrophic lateral sclerosis from two specialised centres in Austria

  2026cites this paper
• Advancements in diagnostic criteria for neuromuscular diseases

  2026cites this paper
• Voxel-mirrored homotopic connectivity in upper motor neuron-dominant amyotrophic lateral sclerosis is associated with different spread directions

  2026influential citation
• The Epidemiology of Primary Lateral Sclerosis: Results from a Population‐Based Cohort

  2025cites this paper
• Unveiling structural damage of the corpus callosum in amyotrophic lateral sclerosis through diffusion tensor imaging and spread direction perspectives

  2025cites this paper
• Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression

  2025cites this paper
• Startle Reflex in Primary Lateral Sclerosis (PLS): A Comparison With Amyotrophic Lateral Sclerosis (ALS)

  2025cites this paper
• Expanding the spectrum of annexin A11 proteinopathy in frontotemporal lobar degeneration and motor neuron disease

  2025cites this paper
• Rate of change in upper and lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis

  2025cites this paper
• Expanding the spectrum of annexin A11 proteinopathy in frontotemporal lobar degeneration and motor neuron disease

  2025cites this paper
• The Role of Gastrostomy and Noninvasive Ventilation in Primary Lateral Sclerosis

  2025cites this paper
• TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis

  2025cites this paper
• Primary Lateral Sclerosis

  2025cites this paper
• Utility of patient subgrouping in ALS clinical trials: a World Federation of Neurology white paper.

  2025cites this paper
• Toward therapeutic trials in primary lateral sclerosis

  2025cites this paper
• Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment

  2025cites this paper
• Motor phenotypes of amyotrophic lateral sclerosis – a three-determinant anatomical classification based on the region of onset, propagation of motor symptoms, and the degree of upper and lower motor neuron dysfunction

  2025cites this paper
• Short-interval intracortical inhibition and facilitation in amyotrophic lateral sclerosis related to disease phenotype.

  2025cites this paper
• Progression and life expectancy in primary lateral sclerosis

  2025cites this paper
• Cutting-edge treatments in amyotrophic lateral sclerosis: the role of molecular pathogenesis in targeted therapies

  2025cites this paper
• Tissue informative cell-free DNA methylation sites in amyotrophic lateral sclerosis

  2024cites this paper
• Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study

  2024cites this paper
• Demographics, characteristics, and clinical profile of motor neuron disease in oman

  2024cites this paper
• Primary Lateral Sclerosis: An Overview

  2024influential citation
• Serial electrodiagnostic testing: Utility and indications in adult neurological disorders

  2024cites this paper
• Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale

  2024cites this paper
• Increased 18F‐THK5351 Uptake at Bilateral Primary Motor Cortex in Patients with Progressive Pseudobulbar Palsy

  2024cites this paper
• Amyotrophic lateral sclerosis; clinical features, differential diagnosis and pathology.

  2024cites this paper
• Postural instability and lower extremity dysfunction in upper motor neuron-dominant amyotrophic lateral sclerosis

  2024cites this paper
• Primary lateral sclerosis: application and validation of the 2020 consensus diagnostic criteria in an expert opinion-based PLS cohort

  2024cites this paper
• Diagnosing primary lateral sclerosis: a clinico-pathological study

  2024cites this paper
• Evaluation of smartphone-based cough data in amyotrophic lateral sclerosis as a potential predictor of functional disability

  2024cites this paper
• DHA/EPA (Omega-3) and LA/GLA (Omega-6) as Bioactive Molecules in Neurodegenerative Diseases

  2023cites this paper
• Serum Neurofilaments in Motor Neuron Disease and Their Utility in Differentiating ALS, PMA and PLS

  2023cites this paper
• The impact of upper and lower motor neuron burden on diagnostic certainty, and clinical course of spinal-onset amyotrophic lateral sclerosis: a cluster-based approach

  2023cites this paper
• Genetic characterization of primary lateral sclerosis

  2023cites this paper
• Diffusion magnetic resonance imaging-based surrogate marker in amyotrophic lateral sclerosis

  2023cites this paper
• Different patterns of spreading direction and motor neurons involvement in a cohort of limb‐onset amyotrophic lateral sclerosis patients from Southern Italy: Potential implication on disease course or progression?

  2023cites this paper
• Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases

  2023cites this paper
• 18F-FDG PET/CT as a molecular biomarker in the diagnosis of amyotrophic lateral sclerosis associated with prostate cancer and progressive supranuclear palsy: A case report

  2023cites this paper
• Clinical Features and Biomarkers to Differentiate Primary and Amyotrophic Lateral Sclerosis in Patients With an Upper Motor Neuron Syndrome

  2023cites this paper
• Utilizing machine learning and lipidomics to distinguish primary lateral sclerosis from amyotrophic lateral sclerosis

  2023cites this paper
• Management of motor neuron disease with updated therapies: A review

  2023cites this paper
• Relationship between cerebrospinal fluid/serum albumin quotient and phenotype in amyotrophic lateral sclerosis: a retrospective study on 328 patients

  2023cites this paper
• Clinical features and genetic spectrum of Chinese patients with hereditary spastic paraplegia: A 14-year study

  2023cites this paper
• Factors associated with the time taken for diagnosis of amyotrophic lateral sclerosis (ALS) in Brazil. An online population-based inquiry

  2023cites this paper
• Performance of serum neurofilament light chain in a wide spectrum of clinical courses of amyotrophic lateral sclerosis—a cross‐sectional multicenter study

  2023cites this paper
• Split-elbow sign in the PRO-ACT and Southern Italy ALS cohorts: a potential marker of disease severity and lower motor neuron involvement?

  2023cites this paper
• Familial motor neuron disease: co-occurrence of PLS and ALS (-FTD)

  2023cites this paper
• Current challenges in primary lateral sclerosis diagnosis

  2023influential citation
• Comparison of spinal magnetic resonance imaging and classical clinical factors in predicting motor capacity in amyotrophic lateral sclerosis

  2023cites this paper
• Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview

  2023cites this paper
• Fast versus slow disease progression in amyotrophic lateral sclerosis-clinical and genetic factors at the edges of the survival spectrum.

  2022cites this paper
• Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases.

  2022cites this paper
• Elevated Plasma Phosphorylated Tau 181 in Amyotrophic Lateral Sclerosis

  2022cites this paper
• Does limited EMG denervation in early primary lateral sclerosis predict amyotrophic lateral sclerosis?

  2022cites this paper
• A review: Management of motor neuron diseases

  2022cites this paper
• Relationship between motor cortical and peripheral axonal hyperexcitability in amyotrophic lateral sclerosis

  2022cites this paper
• Gentherapien bei den Motoneuronerkrankungen ALS und SMA

  2022influential citation
• Age of Onset and Length of Survival of Queensland Patients with Amyotrophic Lateral Sclerosis: Details of Subjects with Early Onset and Subjects with Long Survival

  2022cites this paper
• Motoneuron Diseases.

  2022cites this paper
• Iron-sensitive MR imaging of the primary motor cortex to differentiate hereditary spastic paraplegia from other motor neuron diseases

  2022cites this paper
• Machine learning approaches based on fibroblast morphometry confidently identify stress but have limited ability to predict ALS

  2022influential citation
• Primary lateral sclerosis natural history study – planning, designing, and early enrollment

  2022cites this paper
• Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis

  2021cites this paper
• Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment

  2021cites this paper
• A Case Report on Robot-Aided Gait Training in Primary Lateral Sclerosis Rehabilitation: Rationale, Feasibility and Potential Effectiveness of a Novel Rehabilitation Approach.

  2021cites this paper
• The Benign Course of PLS

  2021influential citation
• Natural History of “Pure” Primary Lateral Sclerosis

  2021influential citation
• Imaging data reveal divergent longitudinal trajectories in PLS, ALS and poliomyelitis survivors: Group-level and single-subject traits

  2021cites this paper
• Gallstone ileus in a patient with amyotrophic lateral sclerosis: A case report

  2021cites this paper
• Amiotrophic Lateral Sclerosis

  2021cites this paper
• Clinical features and incidence trends of amyotrophic lateral sclerosis in Navarre, Spain, 2007–2018: a population-based study

  2021cites this paper
• The panoramic view of amyotrophic lateral sclerosis: A fatal intricate neurological disorder.

  2021cites this paper
• The association of theory of mind with language and visuospatial abilities in amyotrophic lateral sclerosis: a pilot study

  2021cites this paper
• Applications of nose-to-brain delivery in nanodiagnosis and nanotherapy of neurodegenerative disorders

  2021cites this paper
• The Upper Motor Neuron—Improved Knowledge from ALS and Related Clinical Disorders

  2021cites this paper
• Propagation patterns in motor neuron diseases: Individual and phenotype-associated disease-burden trajectories across the UMN-LMN spectrum of MNDs.

  2021cites this paper
• Utility of Transcranial Magnetic Simulation in Studying Upper Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis

  2021cites this paper
• Initial Cerebellar Ataxia in Hereditary Adult-Onset Primary Lateral Sclerosis

  2021cites this paper
• Electromyographic findings in primary lateral sclerosis during disease progression.

  2021cites this paper
• The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS

  2021cites this paper
• Extra-motor cerebral changes and manifestations in primary lateral sclerosis

  2021cites this paper
• Primary Lateral Sclerosis: Clinical, radiological and molecular features.

  2021cites this paper
• Phenotypic variability in amyotrophic lateral sclerosis.

  2021cites this paper
• Upper Motor Neuron Disorders: Primary Lateral Sclerosis, Upper Motor Neuron Dominant Amyotrophic Lateral Sclerosis, and Hereditary Spastic Paraplegia

  2021influential citation
• Estimation of the prevalence and incidence of motor neuron diseases in two Spanish regions: Catalonia and Valencia

  2021cites this paper
• Prevalence of spasticity and spasticity-related pain among patients with Amyotrophic Lateral Sclerosis.

  2021cites this paper
• Cortical Excitability across the ALS Clinical Motor Phenotypes

  2021cites this paper
• What do we know about the variability in survival of patients with amyotrophic lateral sclerosis?

  2020cites this paper
• Neuropathological profile of long‐duration amyotrophic lateral sclerosis in military Veterans

  2020cites this paper
• “Switchboard” malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis

  2020cites this paper
• Primary lateral sclerosis: diagnosis and management

  2020cites this paper
• Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration A neuropsychological and behavioral study of PLS

  2020cites this paper
• Correlation between dysphonia and dysphagia evolution in amyotrophic lateral sclerosis patients

  2020cites this paper
• Clinical care and therapeutic trials in PLS

  2020cites this paper
• Progressive supranuclear palsy and primary lateral sclerosis secondary to globular glial tauopathy: a case report and a practical theoretical framework for the clinical prediction of this rare pathological entity

  2020cites this paper
• Sonographic and 3T-MRI-based evaluation of the tongue in ALS

  2020cites this paper
• Better understanding the neurobiology of primary lateral sclerosis

  2020cites this paper
• Neuroimaging in primary lateral sclerosis

  2020cites this paper