Genetic studies of schizophrenia: an update

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Neuroscience Bulletin

• Publication date

  2015-02-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1007/s12264-014-1494-4PMID 25652814PMCID PMC5562645
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 22q11.2 deletion syndrome

  2015cited by this paper
• Biological Insights From 108 Schizophrenia-Associated Genetic Loci

  2014cited by this paper
• Maternal prenatal infection, early susceptibility to illness and adult psychotic experiences: a birth cohort study.

  2014cited by this paper
• Humanistic burden in schizophrenia: a literature review.

  2014cited by this paper
• Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia.

  2014cited by this paper
• A polygenic burden of rare disruptive mutations in schizophrenia

  2014influential reference
• Transcriptome Sequencing and Genome-wide Association Analyses Reveal Lysosomal Function and Actin Cytoskeleton Remodeling in Schizophrenia and Bipolar Disorder

  2014cited by this paper
• De novo CNVs in bipolar affective disorder and schizophrenia

  2014cited by this paper
• Transcriptional targets of the schizophrenia risk gene MIR137

  2014cited by this paper
• Genome-wide association studies: findings at the major histocompatibility complex locus in psychosis.

  2014cited by this paper
• Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene

  2014cited by this paper
• Further evidence for high rates of schizophrenia in 22q11.2 deletion syndrome.

  2014cited by this paper
• De novo mutations in schizophrenia implicate synaptic networks

  2014cited by this paper
• Copy number variation in schizophrenia in Sweden

  2014cited by this paper
• The association between schizophrenia and rheumatoid arthritis: a nationwide population-based Swedish study on intraindividual and familial risks.

  2014cited by this paper
• A competitive PCR assay confirms the association of a copy number variation in the VIPR2 gene with schizophrenia in Han Chinese.

  2014cited by this paper
• A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137

  2014cited by this paper
• A new paradigm emerges from the study of de novo mutations in the context of neurodevelopmental disease

  2013cited by this paper
• Association between parental hospital-treated infection and the risk of schizophrenia in adolescence and early adulthood.

  2013cited by this paper
• Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: associations and functional implications.

  2013cited by this paper
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

  2013cited by this paper
• Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.

  2013cited by this paper
• Evidence that duplications of 22q11.2 protect against schizophrenia

  2013cited by this paper
• The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants

  2013cited by this paper
• Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia

  2013cited by this paper
• Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

  2013cited by this paper
• Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

  2013cited by this paper
• 22q11 deletion syndrome: a review of the neuropsychiatric features and their neurobiological basis

  2013cited by this paper
• Discovery and refinement of loci associated with lipid levels

  2013cited by this paper
• Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

  2013cited by this paper
• The social defeat hypothesis of schizophrenia: an update.

  2013cited by this paper
• Molecular Genetic Evidence for Genetic Overlap between General Cognitive Ability and Risk for Schizophrenia: A Report from the Cognitive Genomics Consortium (COGENT)

  2013cited by this paper
• Implication of a rare deletion at distal 16p11.2 in schizophrenia.

  2013cited by this paper
• Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia

  2012cited by this paper
• De novo mutations in human genetic disease

  2012cited by this paper
• Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies

  2012cited by this paper
• Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

  2012cited by this paper
• Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

  2012cited by this paper
• CNVs: harbingers of a rare variant revolution in psychiatric genetics.

  2012cited by this paper
• Association analyses of 249 , 796 individuals reveal 18 new loci associated with body mass index

  2012cited by this paper
• Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.

  2012cited by this paper
• De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

  2012influential reference
• Genetic architectures of psychiatric disorders: the emerging picture and its implications

  2012cited by this paper
• Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

  2012cited by this paper
• Copy number variations in neurodevelopmental disorders.

  2012cited by this paper
• Using Summary Data from the Danish National Registers to Estimate Heritabilities for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

  2012cited by this paper
• Impact of a microRNA MIR137 Susceptibility Variant on Brain Function in People at High Genetic Risk of Schizophrenia or Bipolar Disorder

  2012cited by this paper
• Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

  2012influential reference
• New from NPG: Genome-wide association study identifies five new schizophrenia loci

  2011cited by this paper
• Common variants at VRK2 and TCF4 conferring risk of schizophrenia.

  2011cited by this paper
• Association study of RELN polymorphisms with schizophrenia in Han Chinese population.

  2011cited by this paper
• Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries.

  2011cited by this paper
• Duplications of the Neuropeptide Receptor VIPR2 Confer Significant Risk for Schizophrenia

  2011cited by this paper
• Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

  2011cited by this paper
• Increased exonic de novo mutation rate in individuals with schizophrenia

  2011cited by this paper
• High frequencies of de novo CNVs in bipolar disorder and schizophrenia.

  2011cited by this paper
• Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness.

  2011cited by this paper
• GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

  2011cited by this paper
• Exome sequencing supports a de novo mutational paradigm for schizophrenia

  2011cited by this paper
• Genome-Wide Association Study of Schizophrenia in Japanese Population

  2011cited by this paper
• Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

  2011cited by this paper
• Copy number variations of chromosome 16p13.1 region associated with schizophrenia

  2011cited by this paper
• Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

  2011cited by this paper
• Genome-wide association study of schizophrenia in a Japanese population.

  2011cited by this paper
• Molecular mechanisms in 22q11 deletion syndrome.

  2011cited by this paper
• Association of GRIN1 and GRIN2A‐D With schizophrenia and genetic interaction with maternal herpes simplex virus‐2 infection affecting disease risk

  2011cited by this paper
• Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

  2011cited by this paper
• Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.

  2011cited by this paper
• De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

  2011cited by this paper
• De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

  2010cited by this paper
• Direct measure of the de novo mutation rate in autism and schizophrenia cohorts.

  2010cited by this paper
• Copy number variation in schizophrenia in the Japanese population.

  2010cited by this paper
• Replication of an association of a common variant in the Reelin gene (RELN) with schizophrenia in Ashkenazi Jewish women

  2010cited by this paper
• Deletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia.

  2010cited by this paper
• Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.

  2010cited by this paper
• Strong synaptic transmission impact by copy number variations in schizophrenia

  2010cited by this paper
• Reproductive patterns in psychotic patients.

  2010cited by this paper
• De novo truncating mutation in Kinesin 17 associated with schizophrenia.

  2010cited by this paper
• Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

  2010cited by this paper
• Hundreds of variants clustered in genomic loci and biological pathways affect human height

  2010cited by this paper
• New Copy Number Variations in Schizophrenia

  2010cited by this paper
• Microdeletions of 3q29 confer high risk for schizophrenia.

  2010cited by this paper
• A recurrent 16p12.1 microdeletion suggests a two-hit model for severe developmental delay

  2010cited by this paper
• Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function

  2010cited by this paper
• Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia

  2010cited by this paper
• Microduplications of 16p11.2 are Associated with Schizophrenia

  2009cited by this paper
• Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

  2009cited by this paper
• Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

  2009cited by this paper
• Common variants on chromosome 6p22.1 are associated with schizophrenia

  2009cited by this paper
• Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study.

  2009cited by this paper
• Neurexin 1 (NRXN1) deletions in schizophrenia.

  2009cited by this paper
• Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.

  2009cited by this paper
• Common variants conferring risk of schizophrenia

  2009cited by this paper
• A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

  2009cited by this paper
• Disruption of the neurexin 1 gene is associated with schizophrenia.

  2009cited by this paper
• Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.

  2008cited by this paper
• Copy number variations and risk for schizophrenia in 22q11.2 deletion syndrome

  2008cited by this paper
• Sex-specific genetic architecture of human disease

  2008cited by this paper
• Common and rare variants in multifactorial susceptibility to common diseases

  2008influential reference
• Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes.

  2008cited by this paper

• Identification of novel rare variants for anxiety: An exome-wide association study in the UK Biobank.

  2023cites this paper
• Unlocking the Therapeutic Potential of Exosomes Derived From Nasal Olfactory Mucosal Mesenchymal Stem Cells: Restoring Synaptic Plasticity, Neurogenesis, and Neuroinflammation in Schizophrenia.

  2023cites this paper
• Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes

  2023cites this paper
• The Physiological Function of nNOS-Associated CAPON Proteins and the Roles of CAPON in Diseases

  2023cites this paper
• Genetic and functional analysis reveals TENM4 contributes to schizophrenia

  2021cites this paper
• Genetic association of DISC1 variant rs3738401 with susceptibility to Schizophrenia risk in North Indian population

  2021cites this paper
• Reduced Firing of Nucleus Accumbens Parvalbumin Interneurons Impairs Risk Avoidance in DISC1 Transgenic Mice

  2021cites this paper
• The Relation of Gene Polymorphism Interferon Gamma+874 A/T and Schizophrenia Occurred in Batak Ethnicity

  2020cites this paper
• SNPs associated with Schizophrenia: Evidence from Iranian patients

  2020cites this paper
• Mechanisms Underlying the Comorbidity of Schizophrenia and Type 2 Diabetes Mellitus

  2020cites this paper
• A schizophrenia associated CMYA5 allele displays differential binding with desmin.

  2019cites this paper
• Integrating genome-wide association study with regulatory SNP annotation information identified candidate genes and pathways for schizophrenia

  2019influential citation
• Time dependent expression of the blood biomarkers EIF2D and TOX in patients with schizophrenia.

  2019cites this paper
• CYP2D6 genetic polymorphism and genetic ancestry on extrapyramidal side-effects of long-term treatment with classical antipsychotics in cuban patients with schizophrenia

  2019cites this paper
• Assessment of de novo copy-number variations in Italian patients with schizophrenia: Detection of putative mutations involving regulatory enhancer elements

  2019cites this paper
• Investigation into effects of chronic treatment with antipsychotics using a combination of behavioural and electrophysiological techniques

  2019cites this paper
• Double-Edged Sword of Tumour Suppressor Genes in Schizophrenia

  2019cites this paper
• The Effect of Stressful Life Events and Schizophrenia Polygenic Risk on Suicide in Schizophrenia

  2018influential citation
• Altered voxel-wise gray matter structural brain networks in schizophrenia: Association with brain genetic expression pattern

  2018cites this paper
• Imaging genetics of schizophrenia in the post‐GWAS era

  2018cites this paper
• Early Senescence and Leukocyte Telomere Shortening in SCHIZOPHRENIA: A Role for Cytomegalovirus Infection?

  2018cites this paper
• Abnormal brain connectivity in schizophrenia and bipolar disorder – a resting state functional MRI study

  2017cites this paper
• Connecting the Dots

  2017cites this paper
• Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role

  2017cites this paper
• Connectome Disconnectivity and Cortical Gene Expression in Patients With Schizophrenia.

  2017cites this paper
• Potential Value of Genomic Copy Number Variations in Schizophrenia

  2017cites this paper
• Risk of developing psoriasis in patients with schizophrenia: a nationwide retrospective cohort study

  2017cites this paper
• FUNCTIONAL STUDY OF CMYA5, A CANDIDATE GENE FOR SCHIZOPHRENIA

  2017cites this paper
• Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms.

  2017cites this paper
• The genetic architecture of schizophrenia and bipolar disorder: identity by descent and exome sequencing in a family-based population sample

  2016cites this paper
• Proteomics and molecular tools for unveiling missing links in the biochemical understanding of schizophrenia

  2016cites this paper
• Hopes and Expectations Regarding Genetic Testing for Schizophrenia Among Young Adults at Clinical High-Risk for Psychosis

  2016cites this paper
• A current snapshot of common genomic variants contribution in psychiatric disorders

  2016cites this paper
• Research progress in NOS1AP in neurological and psychiatric diseases.

  2016cites this paper
• Screening of three ERBB4 gene polymorphisms in a group of Turkish schizophrenia patients and controls / ERBB4 genindeki üç polimorfizmin bir Türk şizofreni hasta grubunda ve kontrollerde taranması

  2015cites this paper
• The Evolution of Schizophrenia Research and Treatment

  2015cites this paper
• No association between ApoE and schizophrenia: Evidence of systematic review and updated meta-analysis.

  2015cites this paper
• An update on research and approaches in biological psychiatry

  2015cites this paper
• Assessment of Genome-Wide Genetic and Epigenetic De Novo Variation in Families with Monozygotic Twins Discordant for Schizophrenia

  2015influential citation