Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Investigative Ophthalmology and Visual Science

• Publication date

  2005-10-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1167/IOVS.05-0672PMID 16186375
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

  2005cited by this paper
• Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa

  2005cited by this paper
• Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice.

  2005cited by this paper
• Sunlight and Age-Related Macular Degeneration

  2005cited by this paper
• Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells.

  2005cited by this paper
• Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone.

  2005cited by this paper
• Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases.

  2004cited by this paper
• Catalytic site‐specific inhibition of the 20S proteasome by 4‐hydroxynonenal

  2004cited by this paper
• Adenovirus-Mediated Delivery of Catalase to Retinal Pigment Epithelial Cells Protects Neighboring Photoreceptors from Photo-Oxidative Stress

  2004cited by this paper
• Free Radical Trap Phenyl-N-tert-Butylnitrone Protects against Light Damage But Does Not Rescue P23H and S334ter Rhodopsin Transgenic Rats from Inherited Retinal Degeneration

  2003cited by this paper
• Carboxyethylpyrrole Protein Adducts and Autoantibodies, Biomarkers for Age-related Macular Degeneration*

  2003cited by this paper
• The proteasomal system and HNE-modified proteins.

  2003cited by this paper
• Light-dependent Association of Src with Photoreceptor Rod Outer Segment Membrane Proteinsin Vivo *

  2002cited by this paper
• Evidence That Light Modulates Protein Nitration in Rat Retina *

  2002cited by this paper
• Drusen proteome analysis: An approach to the etiology of age-related macular degeneration

  2002cited by this paper
• Low docosahexaenoic acid levels in rod outer segments of rats with P23H and S334ter rhodopsin mutations.

  2002cited by this paper
• Cytoprotective effect of thioredoxin against retinal photic injury in mice.

  2002cited by this paper
• In Vivo Regulation of Phosphoinositide 3-Kinase in Retina through Light-induced Tyrosine Phosphorylation of the Insulin Receptor β-Subunit*

  2002cited by this paper
• Change of redox status and modulation by thiol replenishment in retinal photooxidative damage.

  2002cited by this paper
• Attenuation of retinal photooxidative damage in thioredoxin transgenic mice.

  2002cited by this paper
• Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells.

  2001cited by this paper
• Low docosahexaenoic acid levels in rod outer segment membranes of mice with rds/peripherin and P216L peripherin mutations.

  2001cited by this paper
• Reactive oxygen species‐induced molecular damage and its application in pathology

  1999cited by this paper
• Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man.

  1998cited by this paper
• The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

  1997cited by this paper
• The monoclonal antibody specific for the 4‐hydroxy‐2‐nonenal histidine adduct

  1995cited by this paper
• Prospective incidence of photic maculopathy after cataract surgery.

  1995cited by this paper
• Sunlight and age-related macular degeneration. The Beaver Dam Eye Study.

  1993cited by this paper
• Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes.

  1993cited by this paper
• Cytotoxicity and genotoxicity of lipid-oxidation products.

  1993cited by this paper
• The Beaver Dam Eye Study. Retinopathy in adults with newly discovered and previously diagnosed diabetes mellitus.

  1992cited by this paper
• Lipid peroxidation in rod outer segments. Role of hydroxyl radical and lipid hydroperoxides.

  1992cited by this paper
• Protection by dimethylthiourea against retinal light damage in rats.

  1992cited by this paper
• Modification of histidine residues in proteins by reaction with 4-hydroxynonenal.

  1992cited by this paper
• Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.

  1991cited by this paper
• 4-Hydroxyhexenal: a lipid peroxidation product derived from oxidized docosahexaenoic acid.

  1990cited by this paper
• The protective effect of ascorbate in retinal light damage of rats.

  1985cited by this paper
• Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina.

  1983cited by this paper

• Camellia japonica hyperoside exhibits anti-age-related macular degeneration effects in an ARPE-19 cell model by inhibiting apoptosis via JNK-Nrf2/HO-1 activation.

  2026cites this paper
• Photooxidative molecular damage under blue light

  2026cites this paper
• (Photo)toxicity of Partially Oxidized Docosahexaenoate and Its Effect on the Formation of Lipofuscin in Cultured Human Retinal Pigment Epithelial Cells

  2024cites this paper
• Nutraceuticals for Diabetic Retinopathy: Recent Advances and Novel Delivery Systems

  2024cites this paper
• Response of the Glutathione (GSH) Antioxidant Defense System to Oxidative Injury in Necrotizing Enterocolitis

  2023cites this paper
• Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degeneration

  2023cites this paper
• The essential role of docosahexaenoic acid and its derivatives for retinal integrity.

  2023cites this paper
• Dark matter: Developing a new nanoantioxidant-based therapeutic system for the treatment of age-related macular degeneration

  2023cites this paper
• DHA Shortage Causes the Early Degeneration of Photoreceptors and RPE in Mice With Peroxisomal β-Oxidation Deficiency

  2023cites this paper
• RDH12 retinopathy: clinical features, biology, genetics and future directions

  2022cites this paper
• Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy‐like retinal degeneration in a mouse model with iron overload

  2022cites this paper
• Cholesterol homeostasis in the vertebrate retina: biology and pathobiology

  2021cites this paper
• The Role of Lipoxidation in the Pathogenesis of Diabetic Retinopathy

  2021cites this paper
• Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.

  2021cites this paper
• Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

  2021cites this paper
• Gradual Increase in Environmental Light Intensity Induces Oxidative Stress and Inflammation and Accelerates Retinal Neurodegeneration

  2020cites this paper
• Cholesterol homeostasis in the vertebrate retina: Biology and pathobiology.

  2020cites this paper
• Protective effects of Clostridium butyricum against oxidative stress induced by food processing and lipid-derived aldehydes in Caco-2 cells

  2020cites this paper
• Hyperbaric oxygenation improves redox control and reduces mortality in the acute phase of myocardial infarction in a rat model

  2020cites this paper
• Evolution of oxidative stress, inflammation and neovascularization in the choroid and retina in a subretinal lipid induced age-related macular degeneration model.

  2020cites this paper
• Lipid Oxidation Derived Aldehydes and Oxysterols Between Health and Disease

  2019cites this paper
• Cyanidin-3-glucoside attenuates 4-hydroxynonenal- and visible light-induced retinal damage in vitro and in vivo.

  2019cites this paper
• Oxidized Lipids Decrease Phagocytic Activity of ARPE‐19 Cells In Vitro

  2019cites this paper
• Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Retinal Degenerative Diseases.

  2019cites this paper
• An augmentation in histone dimethylation at lysine nine residues elicits vision impairment following traumatic brain injury.

  2019cites this paper
• Changes in physicochemical properties of kidney cells membrane as a consequence of hypertension and treatment of hypertensive rats with FAAH inhibitor.

  2019cites this paper
• Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation

  2018cites this paper
• Effect of sevoflurane preconditioning on light-induced retinal damage in diabetic rats

  2018cites this paper
• Redox Signaling by Reactive Electrophiles and Oxidants.

  2018cites this paper
• Protection of Rat Retina Against Light-induced Damage by Intraperitoneal and Oral Administration of a Polyphenol Fraction From Seed Shells of Japanese Horse Chestnuts(Aesculus turbinata BLUME)

  2018cites this paper
• Frontiers of Complex Disease Mechanisms: Membrane Surface Tension May Link Genotype to Phenotype in Glaucoma

  2018cites this paper
• Protective Effect of Highly Polymeric A-Type Proanthocyanidins from Seed Shells of Japanese Horse Chestnut (Aesculus turbinata BLUME) against Light-Induced Oxidative Damage in Rat Retina

  2018cites this paper
• Protective effect of crocin against the declining of high spatial frequency-based visual performance in mice

  2018cites this paper
• Quantitative proteomic analysis of aqueous humor from patients with drusen and reticular pseudodrusen in age-related macular degeneration

  2018cites this paper
• 26 Mechanisms of RDH 12-Induced Leber Congenital Amaurosis and Therapeutic Approaches

  2017cites this paper
• Lipid radicals cause light-induced retinal degeneration.

  2017cites this paper
• Salvianolic acid A protects retinal pigment epithelium from OX-LDL-induced inflammation in an age-related macular degeneration model.

  2017cites this paper
• Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

  2017cites this paper
• Increased susceptibility to fundus camera‐delivered light‐induced retinal degeneration in mice deficient in oxidative stress response proteins

  2017cites this paper
• Age related distribution of 4‐hydroxy 2‐nonenal immunoreactivity in human retina

  2017cites this paper
• A model of progressive photo-oxidative degeneration and inflammation in the pigmented C57BL/6J mouse retina.

  2016cites this paper
• Influence of Light Emitting Diode-Derived Blue Light Overexposure on Mouse Ocular Surface

  2016cites this paper
• Protective Effect of Proanthocyanidins from Sea Buckthorn (Hippophae Rhamnoides L.) Seed against Visible Light-Induced Retinal Degeneration in Vivo

  2016cites this paper
• Synthesis of docosahexaenoic acid from eicosapentaenoic acid in retina neurons protects photoreceptors from oxidative stress

  2016cites this paper
• Metabolic and redox signaling in the retina

  2016cites this paper
• Relationship between 4-hydroxy-2-hexenal contents and commercial grade by organoleptic judgement in Japanese dried laver Porphyra spp.

  2016cites this paper
• Stress oxydant et pathologie diabétique : impact de l'hyperglycémie et de l'albumine glyquée sur les cellules cardiaques et adipeuses

  2016cites this paper
• Effects of Chilled Storage, Freezing Rates, and Frozen Storage Temperature on Lipid Oxidation in Meat Blocks from Cultured Bluefin Tuna Thunnus thynnus

  2016cites this paper
• Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells.

  2015cites this paper
• Beneficial protective effect of pramipexole on light-induced retinal damage in mice.

  2015cites this paper
• Oxidative stress increases in retinas of dogs in acute glaucoma but not in chronic glaucoma.

  2015cites this paper
• Light, lipids and photoreceptor survival: live or let die?

  2015cites this paper
• Light Damage in Abca4 and Rpe65 Mice

  2014influential citation
• Light damage in Abca4 and Rpe65rd12 mice.

  2014cites this paper
• Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration.

  2014cites this paper
• Protective effect of light emitting diode phototherapy on fluorescent light induced retinal damage in Wistar strain albino rats.

  2014cites this paper
• Effect of EGb761 on light-damaged retinal pigment epithelial cells.

  2014cites this paper
• Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure.

  2014cites this paper
• Outer Segments of Retinal Photoreceptors - A Review in the Light of Novel Findings

  2014cites this paper
• Protein metabolism during natural ageing in desiccating recalcitrant seeds of Shorea robusta

  2014cites this paper
• Retina Light Damage in Abca 4 and Rpe 65 rd 12 Mice

  2014influential citation
• Accumulation of Hydroxyl Lipids and 4-Hydroxy-2-Hexenal in Live Fish Infected with Fish Diseases

  2014cites this paper
• Mice Exposed to Bright Light in Isolevuglandin-associated Retinal Effects Pretreatment with Pyridoxamine Mitigates Molecular Bases of Disease:

  2014cites this paper
• Retinal Photooxidative Stress and Its Modifiers

  2014cites this paper
• Post-Translational Modification By Isolevuglandins: Retinal Detection, Effects, and Prevention

  2013cites this paper
• Substrate Specificity and Subcellular Localization of the Aldehyde-Alcohol Redox-coupling Reaction in Carp Cones*

  2013cites this paper
• Pretreatment with Pyridoxamine Mitigates Isolevuglandin-associated Retinal Effects in Mice Exposed to Bright Light*

  2013cites this paper
• Blinded by the Light

  2013cites this paper
• Inhibition of de novo ceramide biosynthesis by FTY720 protects rat retina from light-induced degeneration[S]

  2013cites this paper
• Stress Reaction in Outer Segments of Photoreceptors after Blue Light Irradiation

  2013cites this paper
• EFFECT OF ANTIOXIDATIVE TREATMENTS ON LIPID OXIDATION IN SKINLESS FILLET OF PACIFIC SAURY COLOLABIS SAIRA IN FROZEN STORAGE

  2013cites this paper
• 4-Hydroxyhexenal- and 4-Hydroxynonenal-Modified Proteins in Pterygia

  2013cites this paper
• Oxidative stress induced cellular signaling in RPE cells.

  2012cites this paper
• 670-nm light treatment reduces complement propagation following retinal degeneration

  2012cites this paper
• Immunohistochemical detection of polyunsaturated fatty acid oxidation markers in acetaminophen-induced liver injury in rats.

  2012cites this paper
• Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina.

  2012cites this paper
• Oxidative Stress Induced Damage of the Human Retina: Overview of Mechanisms and Preventional Strategies

  2012cites this paper
• Analysis of the light‐sensitivity of the photoreceptor cells of the ataxia and male sterility (AMS) mouse, an Nna1 mutant

  2012cites this paper
• Novel intraocular and systemic absorption drug delivery and efficacy of N‐acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care

  2012cites this paper
• Mechanisms of RDH12-Induced Leber Congenital Amaurosis and Therapeutic Approaches

  2012cites this paper
• Serotonin 5-HT 1A Receptor Agonists in Oxidative Stress and Retinal Disease

  2012cites this paper
• Role of Photoreceptor Retinol Dehydrogenases in Detoxification of Lipid Oxidation Products

  2012cites this paper
• SIMULTANEOUS IDENTIFICATION OF 4-HYDROXY-2-HEXENAL AND 4-HYDROXY-2-NONENAL IN FOODS BY PRE-COLUMN FLUORIGENIC LABELING WITH 1,3-CYCLOHEXANEDIONE AND REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH FLUORESCENCE DETECTION

  2012cites this paper
• Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration*

  2011cites this paper
• Increased Proximal tubule PPAR α in KAP2-PPAR α Tg mice confers protection during acute kidney injury

  2011cites this paper
• Influence of blue light on photoreceptors in a live retinal explant system

  2011cites this paper
• Localization of 4-hydroxy 2-nonenal immunoreactivity in aging human retinal Müller cells.

  2011cites this paper
• α-Phenyl-N-tert-butylnitrone (PBN) Prevents Light-induced Degeneration of the Retina by Inhibiting RPE65 Protein Isomerohydrolase Activity*

  2011cites this paper
• Lipid metabolites in the pathogenesis and treatment of neovascular eye disease

  2011cites this paper
• Orally Active Multi-Functional Antioxidants Are Neuroprotective in a Rat Model of Light-Induced Retinal Damage

  2011cites this paper
• Chapter 61: Photoreceptor Cell Degeneration in Abcr − / − Mice

  2010cites this paper
• Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability.

  2010cites this paper
• Evidence supporting a role for Nε-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy

  2010cites this paper
• Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells.

  2010cites this paper
• Trans-4-hydroxy-2-hexenal, a product of n-3 fatty acid peroxidation: make some room HNE...

  2010cites this paper
• Apical-to-basolateral transcytosis of photoreceptor outer segments induced by lipid peroxidation products in human retinal pigment epithelial cells.

  2010cites this paper
• Correlation between tissue docosahexaenoic acid levels and susceptibility to light-induced retinal degeneration.

  2010cites this paper
• Thematic Review Series: Lipids and Lipid Metabolism in the Eye Phospholipid meets all- trans -retinal: the making of RPE bisretinoids

  2010cites this paper
• Retinal light damage: mechanisms and protection.

  2010cites this paper
• Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration.

  2010cites this paper