Evidence for Neural Effects of Repetition that Directly Correlate with Behavioral Priming

Stimulus repetition associates with neural activity reductions during tasks that elicit behavioral priming. Here we present direct evidence for a quantitative relation between neural activity reductions and behavioral priming. Fifty-four subjects performed a word classification task while being scanned with functional MRI. Activity reductions were found in multiple high-level cortical regions including those within the prefrontal cortex. Importantly, activity within several of these regions, including the prefrontal cortex, correlated with behavior such that greater activity reductions associated with faster performance. Whole-brain correlational analyses confirmed the observation of anatomic overlap between regions showing activity reductions and those showing direct brainbehavioral correlations. The finding of a quantitative relation between neural and behavioral effects in frontal regions suggests that repetition reduces frontally mediated processing in a manner that ultimately facilitates behavior.

• Publication year

  2004

• Venue

  Journal of Cognitive Neuroscience

• Publication date

  2004-11-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1162/0898929042568451PMID 15601524
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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