Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal Genetika

• Publication date

  2014-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12041-014-0405-9PMID 25572253
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Insulin-like Growth Factors

  2024cited by this paper
• [Cachexia in cancer patients].

  2016cited by this paper
• Association of glucokinase regulatory protein polymorphism with type 2 diabetes and fasting plasma glucose: a meta-analysis

  2013cited by this paper
• Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS.

  2013cited by this paper
• Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential?

  2013cited by this paper
• A variant in the LRRFIP1 gene is associated with adiposity and inflammation

  2012cited by this paper
• Is there a genetic cause of appetite loss?—an explorative study in 1,853 cancer patients

  2012cited by this paper
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  2012cited by this paper
• Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

  2012cited by this paper
• rs4215 SNP in zinc-α2-glycoprotein gene is associated with obesity in Chinese north Han population.

  2012cited by this paper
• Glucocorticoid receptor gene polymorphisms are associated with reduced first‐phase glucose‐stimulated insulin secretion and disposition index in women, but not in men

  2012cited by this paper
• C-Reactive Protein Levels and Vitamin D Receptor Polymorphisms as Markers in Predicting Cachectic Syndrome in Cancer Patients

  2012cited by this paper
• P-selectin genotype is associated with the development of cancer cachexia

  2012cited by this paper
• Host immune gene polymorphisms were associated with the prognosis of non‐small‐cell lung cancer in Chinese

  2012cited by this paper
• Worsening Central Sarcopenia and Increasing Intra-Abdominal Fat Correlate with Decreased Survival in Patients with Adrenocortical Carcinoma

  2012cited by this paper
• Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.

  2012cited by this paper
• The cachexia score (CASCO): a new tool for staging cachectic cancer patients

  2011cited by this paper
• Is there a genetic cause for cancer cachexia? – a clinical validation study in 1797 patients

  2011cited by this paper
• Common genetic variation in the IGF1 associates with maximal force output.

  2011cited by this paper
• TRAF6 coordinates the activation of autophagy and ubiquitin-proteasome systems in atrophying skeletal muscle

  2011cited by this paper
• A Single Nucleotide Polymorphism in NF-κB Inducing Kinase Is Associated with Mortality in Septic Shock

  2011cited by this paper
• Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

  2011cited by this paper
• Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review

  2011influential reference
• STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia

  2011influential reference
• Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1).

  2011cited by this paper
• Pitfalls in defining and quantifying cachexia

  2011cited by this paper
• Cox-2 gene polymorphism and IL-6 levels in coronary artery disease.

  2011influential reference
• Definition and classification of cancer cachexia: an international consensus.

  2011influential reference
• The D299G/T399I Toll-Like Receptor 4 Variant Associates with Body and Liver Fat: Results from the TULIP and METSIM Studies

  2010cited by this paper
• Common Variants of TLR1 Associate with Organ Dysfunction and Sustained Pro-Inflammatory Responses during Sepsis

  2010cited by this paper
• Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain.

  2010cited by this paper
• The cancer anorexia/weight loss syndrome: exploring associations with single nucleotide polymorphisms (SNPs) of inflammatory cytokines in patients with non-small cell lung cancer

  2010cited by this paper
• Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors

  2010cited by this paper
• Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics".

  2010cited by this paper
• Interleukin-10 Gene Polymorphisms Influence Susceptibility to Cachexia in Patients with Low-Third Gastric Cancer in a Chinese Population

  2010influential reference
• Association of Interleukin-8 Gene Polymorphism With Cachexia From Patients With Gastric Cancer

  2010cited by this paper
• Consensus on cachexia definitions.

  2010cited by this paper
• Association between functional variants of the ICAM1 and CRP genes and metabolic syndrome in Taiwanese subjects.

  2010cited by this paper
• Genetic variation in the adiponectin receptor 2 (ADIPOR2) gene is associated with coronary artery disease and increased ADIPOR2 expression in peripheral monocytes

  2010cited by this paper
• Cytokine gene polymorphisms and susceptibility to cachexia

  2010cited by this paper
• Association between toll-like receptor polymorphisms and serum levels of tumor necrosis factor-alpha and its soluble receptors in obese children.

  2010cited by this paper
• Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids.

  2010cited by this paper
• SCAN: SNP and copy number annotation

  2010cited by this paper
• PI3 kinase regulation of skeletal muscle hypertrophy and atrophy.

  2010cited by this paper
• Association of interleukin-10 gene polymorphism with cachexia in Chinese patients with gastric cancer.

  2010cited by this paper
• Systemic zinc redistribution and dyshomeostasis in cancer cachexia

  2010cited by this paper
• Mechanisms of TNF-alpha-induced insulin resistance.

  2009cited by this paper
• Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

  2009cited by this paper
• Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.

  2009cited by this paper
• Clinical Features Associated with Glucocorticoid Receptor Polymorphisms

  2009cited by this paper
• Cardiac cachexia: a systematic overview.

  2009cited by this paper
• Association between ACE D allele and elite short distance swimming

  2009cited by this paper
• Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men.

  2009influential reference
• The emerging role of computerized tomography in assessing cancer cachexia

  2009cited by this paper
• The lipin family: mutations and metabolism

  2009cited by this paper
• Smad2 and 3 transcription factors control muscle mass in adulthood.

  2009cited by this paper
• Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet‐induced weight loss

  2009cited by this paper
• Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.

  2009cited by this paper
• Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

  2009cited by this paper
• Defining and classifying cancer cachexia: a proposal by the SCRINIO Working Group.

  2009cited by this paper
• Maternal TLR4 and NOD2 Gene Variants, Pro-Inflammatory Phenotype and Susceptibility to Early-Onset Preeclampsia and HELLP Syndrome

  2008cited by this paper
• Natural selection has driven population differentiation in modern humans

  2008cited by this paper
• Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.

  2008cited by this paper
• Adipokines and ghrelin in gastric cancer cachexia.

  2008cited by this paper
• The future of mouse QTL mapping to diagnose disease in mice in the age of whole-genome association studies.

  2008cited by this paper
• Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

  2008cited by this paper
• Association of IL-6 gene polymorphisms with cachexia susceptibility and survival time of patients with pancreatic cancer.

  2008cited by this paper
• Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density

  2008cited by this paper
• Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

  2008cited by this paper
• A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

  2008cited by this paper
• Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.

  2008cited by this paper
• Mapping the Genetic Architecture of Gene Expression in Human Liver

  2008cited by this paper
• Cachexia, survival and the acute phase response

  2008cited by this paper
• Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice.

  2008cited by this paper
• Effect of the −420C/G variant of the resistin gene promoter on metabolic syndrome, obesity, myocardial infarction and kidney dysfunction

  2007cited by this paper
• A Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs

  2007cited by this paper
• Preliminary Results

  2007cited by this paper
• Cooperation of Toll-like receptor signals in innate immune defence

  2007cited by this paper
• Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study.

  2007cited by this paper
• Molecular evidence for a link between the N363S glucocorticoid receptor polymorphism and altered gene expression.

  2007cited by this paper
• Overweight/obesity and cancer genesis: more than a biological link.

  2007cited by this paper
• Peroxisome Proliferator‐activated Receptor γ 2 and Acyl‐CoA Synthetase 5 Polymorphisms Influence Diet Response

  2007cited by this paper
• Presence of lipoprotein lipase S447X stop codon affects the magnitude of interleukin 8 release after cardiac surgery with cardiopulmonary bypass.

  2007cited by this paper
• Association of IL-1beta gene polymorphism with cachexia from locally advanced gastric cancer

  2007cited by this paper
• Interleukin-1 genetic polymorphisms and their relationship to the cancer anorexia/weight loss syndrome in metastatic gastric and gastroesophageal junction adenocarcinoma.

  2007cited by this paper
• Differential binding of proteins to the IL1B -31 T/C polymorphism in lung epithelial cells.

  2007cited by this paper
• IL18 haplotypes are associated with serum IL-18 concentrations in a population-based study and a cohort of individuals with premature coronary heart disease.

  2007cited by this paper
• TLR signaling.

  2006cited by this paper
• The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes.

  2006cited by this paper
• TLR signaling.

  2006cited by this paper
• Human Resistin Is a Systemic Immune-Derived Proinflammatory Cytokine Targeting both Leukocytes and Adipocytes

  2006cited by this paper
• P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.

  2006cited by this paper
• IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy.

  2006cited by this paper
• IL-18 gene polymorphisms affect IL-18 production capability by monocytes.

  2006cited by this paper
• Cancer cachexia and fatigue.

  2006cited by this paper
• EFFECTS OF HAPLOTYPES IN THE INTERLEUKIN 1&bgr; PROMOTER ON LIPOPOLYSACCHARIDE-INDUCED INTERLEUKIN 1&bgr; EXPRESSION

  2006cited by this paper
• Interleukin-1 system gene polymorphisms are associated with fat mass in young men.

  2006cited by this paper
• The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians

  2006cited by this paper
• The Leu7Pro polymorphism of neuropeptide Y is associated with younger age of onset of type 2 diabetes mellitus and increased risk for nephropathy in subjects with diabetic retinopathy.

  2006cited by this paper
• Lipoprotein lipase gene S447X polymorphism modulates the relation between central obesity and serum lipids, a twin study

  2006cited by this paper

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• A genome wide association study to identify germline copy number variants associated with cancer cachexia: a preliminary analysis

  2024cites this paper
• Routine assessment of nutritional, functional and inflammatory criteria in patients with cancer: A systematic review.

  2024cites this paper
• Association of the rs3917647 polymorphism of the SELP gene with malnutrition in gastric cancer

  2023cites this paper
• Current Therapeutic Targets in Cancer Cachexia: A Pathophysiologic Approach.

  2023cites this paper
• TNF-α-1031T/C gene polymorphism as a predictor of malnutrition in patients with gastric cancer

  2023cites this paper
• A genome wide association study to identify germline variants associated with cancer-associated cachexia - a preliminary analysis

  2023cites this paper
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• Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease

  2021cites this paper
• Nutritional Deficiencies in Radiotherapy-Treated Head and Neck Cancer Patients

  2021cites this paper
• IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia.

  2019cites this paper
• Polymorphisms in CPT1B and CPT2 have no significant effect on plasma carnitine levels in Japanese cancer patients

  2019cites this paper
• Cancer-associated cachexia

  2018cites this paper
• miRNA-130a Significantly Improves Accuracy of SGA Nutritional Assessment Tool in Prediction of Malnutrition and Cachexia in Radiotherapy-Treated Head and Neck Cancer Patients

  2018cites this paper
• Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1

  2017cites this paper
• Biomarkers of cancer cachexia.

  2017cites this paper
• Association of gene variants of transcription factors PPARγ, RUNX2, Osterix genes and COL2A1, IGFBP3 genes with the development of osteonecrosis of the femoral head in Chinese population.

  2017cites this paper
• Differentially expressed alternatively spliced genes in skeletal muscle from cancer patients with cachexia

  2017cites this paper
• Variants of GSK3β and SFRP4 genes in Wnt signaling were not associated with osteonecrosis of the femoral head

  2017cites this paper
• Association between FTO gene polymorphism (rs9939609 T/A) and cancer risk: a meta‐analysis

  2017cites this paper
• Die Rolle früher parenteraler Ernährung bei Tumorpatienten

  2016cites this paper
• Diagnostic criteria for cancer cachexia: data versus dogma

  2016cites this paper
• New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss

  2016cites this paper
• Cancer tolerance, resistance, pathogenicity and virulence: deconstructing the disease state.

  2016cites this paper
• STAT3 in the systemic inflammation of cancer cachexia.

  2016cites this paper
• Practical multimodal care for cancer cachexia

  2016cites this paper
• Omics/systems biology and cancer cachexia.

  2016cites this paper
• Nutritional problems among patients affected by cancer during chemotherapy

  2015cites this paper
• Exercise for cancer cachexia in adults: Executive summary of a Cochrane Collaboration systematic review

  2015cites this paper