B‐cells with a FasL expressing regulatory phenotype are induced following successful anti‐tuberculosis treatment

Studies show that B‐cells, in addition to producing antibodies and antigen‐presentation, are able to produce cytokines as well. These include regulatory cytokines such as IL‐10 by regulatory B‐cells. Furthermore, a rare regulatory subset of B‐cells have the potential to express FasL, which is a death‐inducing ligand. This subset of B‐cells have a positive role during autoimmune disease, but has not yet been studied during tuberculosis. These FasL‐expressing B‐cells are induced by bacterial LPS and CpG, thus we hypothesized that this phenotype might be induced during tuberculosis as well.

• Publication year

  2016

• Venue

  Immunity, Inflammation and Disease

• Publication date

  2016-12-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/iid3.140PMID 28250925PMCID 5322165
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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