Localized modulated wave solutions in diffusive glucose–insulin systems

Abstract We investigate intercellular insulin dynamics in an array of diffusively coupled pancreatic islet β -cells. The cells are connected via gap junction coupling, where nearest neighbor interactions are included. Through the multiple scale expansion in the semi-discrete approximation, we show that the insulin dynamics can be governed by the complex Ginzburg–Landau equation. The localized solutions of this equation are reported. The results suggest from the biophysical point of view that the insulin propagates in pancreatic islet β -cells using both temporal and spatial dimensions in the form of localized modulated waves.

• Publication year

  2015

• Venue

  Physics Letters A

• Publication date

  2015-08-21

• Fields of study

  Biology, Physics

• Identifiers
  DOI 10.1016/j.physleta.2016.04.039arXiv 1508.05226
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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