Glyphosate inhibits melanization of Cryptococcus neoformans and prolongs survival of mice after systemic infection.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Infectious Diseases

• Publication date

  2001-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1086/319272PMID 11237835
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antioxidant systems in the pathogenic fungi of man and their role in virulence.

  2008cited by this paper
• Melanisation of Cryptococcus neoformans in human brain tissue.

  2000cited by this paper
• Synthesis of Polymerized Melanin by Cryptococcus neoformans in Infected Rodents

  2000cited by this paper
• Characterization of an Anticryptococcal Protein Isolated from Human Serum

  2000cited by this paper
• Prevalence of Cryptococcus neoformans var. neoformans (Serotype D) and Cryptococcus neoformans var. grubii (Serotype A) isolates in New York City.

  2000cited by this paper
• Evidence That Cryptococcus neoformans Is Melanized in Pigeon Excreta: Implications for Pathogenesis

  1999cited by this paper
• Early mycological treatment failure in AIDS-associated cryptococcal meningitis.

  1999cited by this paper
• Glyphosate reduces organism viability and inhibits growth in vitro of Pneumocystis.

  1999cited by this paper
• Melanization of Cryptococcus neoformansin Murine Infection

  1999cited by this paper
• Melanization of Cryptococcus neoformans in Murine Infection

  1998cited by this paper
• Evidence for the shikimate pathway in apicomplexan parasites

  1998cited by this paper
• Melanin Biosynthesis in Cryptococcus neoformans

  1998cited by this paper
• Predicting stability constants of various chelating agents using QSAR technology

  1997cited by this paper
• Cellular charge of Cryptococcus neoformans: contributions from the capsular polysaccharide, melanin, and monoclonal antibody binding

  1997cited by this paper
• Glyphosate: A Unique Global Herbicide

  1997cited by this paper
• Cryptococcosis in the era of AIDS 100 years after the discovery of Cryptococcus neoformans

  1997cited by this paper
• An EPSP synthase inhibitor joining shikimate 3-phosphate with glyphosate: synthesis and ligand binding studies.

  1996cited by this paper
• Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans

  1996cited by this paper
• Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans

  1996cited by this paper
• Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

  1995cited by this paper
• Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans.

  1995cited by this paper
• Estimation of the prevalence of cryptococcal infection among patients infected with the human immunodeficiency virus in New York City.

  1994cited by this paper
• (6S)-6-fluoroshikimic acid, an antibacterial agent acting on the aromatic biosynthetic pathway

  1994cited by this paper
• Persistence of initial infection in recurrent Cryptococcus neoformans meningitis.

  1993cited by this paper
• A standardized test for the identification and characterization of melanins using electron paramagnetic resonance (EPR) spectroscopy.

  1993cited by this paper
• Management of cryptococcosis.

  1993cited by this paper
• Heterogeneity of phenol oxidases in Cryptococcus neoformans

  1992cited by this paper
• Melanin standard method: empirical formula 2.

  1992cited by this paper
• The function of melanin or six blind people examine an elephant.

  1992cited by this paper
• Molecular cloning, characterization and analysis of the regulation of the AR02 gene, encoding chorismate synthase, of Saccharomyces cerevisiae

  1991cited by this paper
• Emerging technologies in hazardous waste management

  1990cited by this paper
• Melanins and their importance in pathogenic fungi.

  1988cited by this paper
• Amino acid biosynthesis inhibitors as herbicides.

  1988cited by this paper
• Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment.

  1986cited by this paper
• METAL CHELATE FORMATION BY N-PHOSPHONOMETHYLGLYCINE AND RELATED LIGANDS

  1985cited by this paper
• Mode of action of glyphosate in Candida maltosa

  1984cited by this paper
• Free radicals in molecular biology, aging, and disease

  1984cited by this paper
• Isolation of the ARO1 cluster gene of Saccharomyces cerevisiae

  1983cited by this paper
• Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice

  1982cited by this paper
• Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans

  1982cited by this paper
• The herbicide glyphosate is a potent inhibitor of 5-enolpyruvyl-shikimic acid-3-phosphate synthase.

  1980cited by this paper
• Stability Constants of Copper(II), Zinc, Manganese(II), Calcium, and Magnesium Complexes of N-(Phosphonomethyl)glycine (Glyphosate).

  1978cited by this paper
• Comparative biochemistry of the phenolase complex.

  1955cited by this paper

• Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation

  2025cites this paper
• Immunomodulatory functions of fungal melanins in respiratory infections

  2025cites this paper
• Antifungal Activity of 8-Hydroxyquinoline Derivatives Against Candida auris, Candida haemulonii, Cryptococcus neoformans, and Cryptococcus gattii Complex

  2025cites this paper
• The Hidden Threat: Unveiling the Rise of Antifungal Drug Resistance.

  2025cites this paper
• Effect of glyphosate on the sporulation of aquatic fungi: an in-vitro experience

  2024cites this paper
• The biofilm produced by Cryptococcus neoformans protects the fungus from the antifungal and anti-melanin effects of cyclosporine.

  2024cites this paper
• Cell wall melanin impedes growth of the Cryptococcus neoformans polysaccharide capsule by sequestering calcium

  2024cites this paper
• Cell wall melanin impedes growth of the Cryptococcus neoformans polysaccharide capsule by sequestering calcium

  2024cites this paper
• Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication

  2024cites this paper
• AccsHSP21.7 enhances the antioxidant capacity of Apis cerana cerana.

  2023cites this paper
• A New Perspective on Metabolites and Bioactive Compounds from Fungi.

  2023cites this paper
• The effects of glyphosate, pure or in herbicide formulation, on bumble bees and their gut microbial communities.

  2023cites this paper
• Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella

  2022cites this paper
• In silico and in vitro studies on the inhibition of laccase activity by Ellagic acid: Implications in drug designing for the treatment of Cryptococcal infections.

  2022cites this paper
• Glyphosate induces immune dysregulation in honey bees

  2022cites this paper
• Effect of Melanin Biosynthesis Inhibition on the Antifungal Susceptibility of Chromoblastomycosis Agents

  2021cites this paper
• OPPORTUNISTIC FUNGI AS CONTAMINANTS OF HUMAN ENVIRONMENT AND THEIR POTENTIAL PATHOGENICITY

  2021cites this paper
• Skin and soft tissue infections

  2021cites this paper
• Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways

  2021cites this paper
• References

  2021cites this paper
• Direct herbicide effects on terrestrial nontarget organisms belowground and aboveground

  2021cites this paper
• Fungal Melanins and Applications in Healthcare, Bioremediation and Industry

  2021cites this paper
• Glyphosate inhibits melanization and increases susceptibility to infection in insects

  2021influential citation
• The impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity

  2020cites this paper
• Immunological efficiency of microbial melanin on bacterial pathogenicity.

  2020cites this paper
• Coumaric acid analogues inhibit growth and melanin biosynthesis in Cryptococcus neoformans and potentialize amphotericin B antifungal activity.

  2020cites this paper
• Glyphosate Inhibits Melanization and Increases Insect Susceptibility to Infection

  2020cites this paper
• New Approaches for Cryptococcosis Treatment

  2020cites this paper
• Targeting virulence factors as an antimicrobial approach: Pigment inhibitors

  2020cites this paper
• Fungal Physiology and Immunopathogenesis

  2019cites this paper
• Effect of non-antifungal agrochemicals on the pathogenic fungus Cryptococcus gattii.

  2019cites this paper
• The Role of Melanin in Fungal Pathogenesis for Animal Hosts.

  2019cites this paper
• Autolytic enzymes are responsible for increased melanization of carbon stressed Aspergillus nidulans cultures

  2018cites this paper
• Cell-wall dyes interfere with Cryptococcus neoformans melanin deposition.

  2018cites this paper
• Pharmacological inhibition of pigmentation in Cryptococcus.

  2018cites this paper
• A potential of propolis on major virulence factors of Cryptococcus neoformans.

  2018cites this paper
• Functions of fungal melanin beyond virulence.

  2017cites this paper
• Processes Underlining the Action of Pesticides on Ecosystems and Human Organism

  2017cites this paper
• Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis

  2017cites this paper
• Molecular Evolution of Antifungal Drug Resistance.

  2017cites this paper
• The Crucial Role of Biofilms in Cryptococcus neoformans Survival within Macrophages and Colonization of the Central Nervous System

  2017cites this paper
• Factors affecting mycelium pigmentation and pathogenicity of Sclerotinia sclerotiorum on Valencia peanut

  2016cites this paper
• Functions of Fungal Melanins

  2016cites this paper
• Cryptococcal therapies and drug targets: the old, the new and the promising

  2016cites this paper
• Virulence Factors as Targets for Anticryptococcal Therapy

  2016cites this paper
• On the Evolution of Catalysis: The changing kinetics of core metabolic enzymes

  2015cites this paper
• Fungal Melanin: What do We Know About Structure?

  2015cites this paper
• Role of Cln1 during melanization of Cryptococcus neoformans

  2015influential citation
• The Role of Amino Acid Permeases and Tryptophan Biosynthesis in Cryptococcus neoformans Survival

  2015cites this paper
• Activation of Melanin Synthesis in Alternaria infectoria by Antifungal Drugs

  2015cites this paper
• Virulence-Associated Enzymes of Cryptococcus neoformans

  2015cites this paper
• TOXICIDAD in vitro DE LOS HERBICIDAS ATRAZINA Y PARAQUAT SOBRE EL CRECIMIENTO VEGETATIVO Y LA ESPORULACIÓN DE HONGOS SAPROBIOS DEL SUELO

  2014cites this paper
• Regulation of vacuolar trafficking by Vps45p in the pathogenic fungus Cryptococcus neoformans

  2014cites this paper
• Evaluation of Apple Hydro Extracts on Liver Enzyme ALT , AST and ALK in Female Rats Receiving Glyphosate Toxins

  2014cites this paper
• Effect of the herbicide Glyphosate on renal tissues in adult female rats

  2014cites this paper
• اثر علف کش گلیفوزیت بر بافت کلیه در موش های صحرایی ماده بالغ

  2013cites this paper
• Kinetics and Mechanism of Inhibition of Oxidation Enzymes by Herbicides

  2013cites this paper
• Protective role of Aspergillus fumigatus melanin against ultraviolet (UV) irradiation and Bjerkandera adusta melanin as a candidate vaccine against systemic candidiasis

  2012cites this paper
• 4 Unexpected Side Effects of Herbicides : Modulation of Plant-Pathogen Interactions

  2012cites this paper
• Biosynthesis and Functions of a Melanoid Pigment Produced by Species of the Sporothrix Complex in the Presence of l-Tyrosine

  2012cites this paper
• Melanogenesis in dermatophyte species in vitro and during infection.

  2011cites this paper
• Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans.

  2011cites this paper
• An Investigation into Bioactive Proteins and Their Changes During Imbibition, Germination and Development of Red Kidney Bean Seeds (Phaseolus vulgaris L.)

  2011cites this paper
• Unexpected Side Effects of Herbicides: Modulation of Plant-Pathogen Interactions

  2011cites this paper
• Melanin: Structure, Function, and Biosynthesis in Cryptococcus

  2011cites this paper
• Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans.

  2011cites this paper
• Synthesis and assembly of fungal melanin

  2011cites this paper
• [Melanin and its role on the virulence of Cryptococcus neoformans].

  2010cites this paper
• The effects of glyphosate on the in vitro linear growth of selected microfungi from a boreal forest soil.

  2010cites this paper
• Platypus mucormycosis and its conservation implications.

  2009cites this paper
• Melanin production at 37°C is linked to the high virulent Cryptococcus gattii Vancouver Island outbreak genotype VGIIa.

  2009cites this paper
• Vesicle-associated melanization in Cryptococcus neoformans.

  2009cites this paper
• Color me bad: microbial pigments as virulence factors.

  2009cites this paper
• Virulence factors and their mechanisms of action: the view from a damage-response framework.

  2009cites this paper
• The in vitro effect of the herbicide Basta® (glufosinate ammonium) on potential fungal grapevine pathogens

  2009cites this paper
• Antioxidant systems in the pathogenic fungi of man and their role in virulence.

  2008cites this paper
• Melanin as a virulence factor of Paracoccidioides brasiliensis and other dimorphic pathogenic fungi: a minireview

  2008cites this paper
• VORICONAZOLE INHIBITS MELANIZATION IN

  2007cites this paper
• Pathogenesis of Cryptococcus neoformans

  2007cites this paper
• Cryptococcus neoformans laccase catalyses melanin synthesis from both D- and L-DOPA.

  2007cites this paper
• Voriconazole Inhibits Melanization in Cryptococcus neoformans

  2007cites this paper
• Time- and Dose-Dependent Effects of Roundup on Human Embryonic and Placental Cells

  2007cites this paper
• Melanin biosynthesis in Madurella mycetomatis and its effect on susceptibility to itraconazole and ketoconazole.

  2007cites this paper
• Influence of glyphosate on Rhizoctonia and Fusarium root rot in sugar beet.

  2006cites this paper
• Impact of Melanin on Microbial Virulence and Clinical Resistance to Antimicrobial Compounds

  2006cites this paper
• Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?

  2006cites this paper
• Melanization of Cryptococcus neoformans Affects Lung Inflammatory Responses during Cryptococcal Infection

  2005cites this paper
• Inhibition of melanin synthesis pathway by tricyclazole increases susceptibility of Fonsecaea pedrosoi against mouse macrophages

  2005cites this paper
• Inhibition of the nicotinamide adenine dinucleotide-oxidoreductase reaction by herbicides and fungicides of various structures

  2005cites this paper
• General metabolism of the dimorphic and pathogenic fungus Paracoccidioides brasiliensis.

  2005cites this paper
• The multitude of targets for the immune system and drug therapy in the fungal cell wall.

  2005cites this paper
• Biodegradation of glyphosate by wild yeasts

  2004cites this paper
• Blastomyces dermatitidis produces melanin in vitro and during infection.

  2004cites this paper
• Melanized Fungi Infecting Humans: Function of Melanin as a Factor in Pathogenesis

  2004cites this paper
• Scytalidium dimidiatum Causing Recalcitrant Subcutaneous Lesions Produces Melanin

  2004cites this paper
• Ichthyophthirius multifiliis and Tetrahymena thermophila Tolerate Glyphosate But Not a Commercial Herbicidal Formulation

  2003cites this paper
• Budding of melanized Cryptococcus neoformans in the presence or absence of L-dopa.

  2003influential citation
• The contribution of melanin to microbial pathogenesis

  2003cites this paper
• Antifungal therapy--state of the art at the beginning of the 21st century.

  2003cites this paper
• Synthesis of Melanin-Like Pigments by Sporothrix schenckii In Vitro and during Mammalian Infection

  2003cites this paper