Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cancer Research

• Publication date

  2007-04-15

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1158/0008-5472.CAN-06-4250PMID 17440099
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs.

  2006cited by this paper
• Optimizing therapy for patients with brain metastases.

  2006cited by this paper
• The Early-Immediate Gene EGR-1 Is Induced by Transforming Growth Factor-β and Mediates Stimulation of Collagen Gene Expression*

  2006cited by this paper
• Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells

  2006cited by this paper
• Stress-specific signatures: expression profiling of p53 wild-type and -null human cells

  2005cited by this paper
• Prediction of radiation sensitivity using a gene expression classifier.

  2005cited by this paper
• STAT1 Signaling Regulates Tumor-Associated Macrophage-Mediated T Cell Deletion1

  2005cited by this paper
• STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

  2005cited by this paper
• Expression of mRNA coding for TGF-beta and its receptors in irradiated human breast carcinoma MCF-7 cells differing in their sensitivity to doxorubicin.

  2005cited by this paper
• STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.

  2004cited by this paper
• Involvement of LEU13 in Interferon-Induced Refractoriness of Human RSa Cells to Cell Killing by X Rays

  2003cited by this paper
• Functional p53 increases prostate cancer cell survival after exposure to fractionated doses of ionizing radiation.

  2003cited by this paper
• Computerized Video Time-Lapse (CVTL) Analysis of Cell Death Kinetics in Human Bladder Carcinoma Cells (EJ30) X-Irradiated in Different Phases of the Cell Cycle

  2002influential reference
• A phase I study of fludarabine combined with radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinoma.

  2002cited by this paper
• Alterations of expression and regulation of transforming growth factor beta in human cancer prostate cell lines.

  2002cited by this paper
• Signalling: STATs: transcriptional control and biological impact

  2002cited by this paper
• Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.

  2002influential reference
• Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins.

  2001influential reference
• p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors.

  1999cited by this paper
• Functional Roles of STAT Family Proteins: Lessons from Knockout Mice

  1999cited by this paper
• Response of human tumor cells of varying radiosensitivity and radiocurability to fractionated irradiation.

  1999cited by this paper
• Radiation-enhanced expression of interferon-inducible genes in the KG1a primitive hematopoietic cell line

  1997cited by this paper
• Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

  1997influential reference
• Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy.

  1996influential reference
• Modulation of Interferon (IFN)-inducible Gene Expression by Retinoic Acid

  1996cited by this paper
• Secretion of Transforming Growth Factor-1 and -2 by Malignant Glioma Cells

  1995cited by this paper
• Secretion of transforming growth factor-beta 1 and -beta 2 by malignant glioma cells.

  1995cited by this paper
• Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

  1992cited by this paper
• Establishment and characterization of a cell line from a human gliosarcoma.

  1986cited by this paper
• Four R's of radiotherapy

  1975cited by this paper

• Phytogalactolipids triggered oxidative stress to inhibit drug-resistant colorectal cancer by suppressing interferon-α-induced protein 6.

  2026cites this paper
• Optimized patient-derived lung cancer organoids recapitulating the immune landscape for precision therapy evaluation

  2026cites this paper
• “Cytokine-Mediated tumor sensitization: mechanistic frameworks and therapeutic opportunities in cancer Immunotherapy”

  2026cites this paper
• Pan-cancer multi-omics profiling of OAS3 reveals its immunological and prognostic associations across human cancers

  2026cites this paper
• IRF2-driven upregulation of OAS3 promotes AML cell proliferation by modulating the JAK-STAT signaling pathway.

  2025cites this paper
• Single-dose radiotherapy is more effective than fractionation when combined with anti-PD-1 immunotherapy in glioblastoma

  2025cites this paper
• Understanding the Radiobiology of Central Nervous System Diseases in the Golden Age of Radiosurgery—Does It Matter?

  2025influential citation
• Thbs1+ extracellular vesicles from irradiated tumors induce cardiac wasting via PERK-eIF2α-Atf4 signaling.

  2025cites this paper
• Inverse dose protraction effects of low-LET radiation: evidence and significance.

  2025cites this paper
• Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer

  2025cites this paper
• In situ vaccination caused by diverse irradiation-driven cell death programs

  2024cites this paper
• Integrated network pharmacology and transcriptomics to reveal the mechanism of Passiflora against depressive disorder: An observational study

  2024cites this paper
• Multiomic-Based Molecular Landscape of FaDu Xenograft Tumors in Mice after a Combinatorial Treatment with Radiation and an HSP90 Inhibitor Identifies Adaptation-Induced Targets of Resistance and Therapeutic Intervention

  2024cites this paper
• Unraveling the Role of RNase L Knockout in Alleviating Immune Response Activation in Mice Bone Marrow after Irradiation

  2024cites this paper
• DDX58 deficiency leads to triple negative breast cancer chemotherapy resistance by inhibiting Type I IFN-mediated signalling apoptosis

  2024cites this paper
• The efficacy and safety of stereotactic body radiotherapy combined with systematic therapy for metastatic renal cell carcinoma: a systematic review and meta‐analysis

  2024cites this paper
• A model and multi-core parallel co-evolution algorithm for identifying cancer driver pathways

  2024cites this paper
• A Partial Tumor Irradiation Approach for Complex Bulky Disease.

  2024cites this paper
• The curious case of interferon-1 signaling in cancer.

  2024cites this paper
• Irradiation-induced IFN-type-I pathway activation in prostate cancer cell lines.

  2023cites this paper
• Insights on the Radiation-Induced Adaptive Response at the Cellular Level and Its Implications in Cancer Therapy

  2023cites this paper
• Occludin regulates HIV-1 infection by modulation of the interferon stimulated OAS gene family

  2023cites this paper
• Bioinformatics analyses of combined databases identify shared differentially expressed genes in cancer and autoimmune disease

  2023cites this paper
• The Current and Future Promises of Combination Radiation and Immunotherapy for Genitourinary Cancers

  2022cites this paper
• Radiation-induced remodeling of the tumor-microenvironment through tumor cell-intrinsic expression of cGAS-STING in esophageal squamous cell carcinoma.

  2022cites this paper
• The Molecular and Cellular Strategies of Glioblastoma and Non-Small-Cell Lung Cancer Cells Conferring Radioresistance

  2022cites this paper
• Interferon Gamma, MHC Class I Regulation and Immunotherapy

  2022cites this paper
• The Yin and Yang of Type I IFNs in Cancer Promotion and Immune Activation

  2021cites this paper
• Metabolic response to radiation therapy in cancer

  2021cites this paper
• Biological Bases of Immune-Related Adverse Events and Potential Crosslinks With Immunogenic Effects of Radiation

  2021cites this paper
• Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells

  2021cites this paper
• Kickstarting Immunity in Cold Tumours: Localised Tumour Therapy Combinations With Immune Checkpoint Blockade

  2021cites this paper
• Impact of STAT Proteins in Tumor Progress and Therapy Resistance in Advanced and Metastasized Prostate Cancer

  2021cites this paper
• A Novel Approach for the Discovery of Biomarkers of Radiotherapy Response in Breast Cancer

  2021cites this paper
• Long-term expression changes of immune-related genes in prostate cancer after radiotherapy

  2021cites this paper
• Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

  2021cites this paper
• Overcoming Resistance to Immunotherapy in Head and Neck Cancer Using Radiation: A Review

  2021cites this paper
• Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation

  2021cites this paper
• Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes

  2021cites this paper
• Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy

  2021cites this paper
• Combined Treatment of Radiotherapy and Immunotherapy for Urological Malignancies: Current Evidence and Clinical Considerations

  2021cites this paper
• Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages

  2020cites this paper
• Interferon α in cancer immunoediting: From elimination to escape

  2020cites this paper
• Sixteenth Annual Warren K. Sinclair Keynote Address: Frontiers in Medical Radiation Science.

  2020cites this paper
• The mechanism of how CD95/Fas activates the Type I IFN/STAT1 axis, driving cancer stemness in breast cancer

  2020cites this paper
• Radiation-induced Adaptive Response: New Potential for Cancer Treatment

  2020cites this paper
• Deciphering the Roles of IFITM1 in Tumors

  2020cites this paper
• OTT_A_256708 6037..6050

  2020cites this paper
• Hypofractionated Stereotactic Radiosurgery for Intact and Resected Brain Metastases

  2020cites this paper
• Targeting IFN/STAT1 Pathway as a Promising Strategy to Overcome Radioresistance

  2020cites this paper
• Radiation Induced Upregulation of DNA Sensing Pathways is Cell-Type Dependent and Can Mediate the Off-Target Effects

  2020cites this paper
• Inflammatory microenvironment remodelling by tumour cells after radiotherapy

  2020cites this paper
• Effective combinations of radiotherapy and immunotherapy in the treatment of esophageal squamous cell carcinoma.

  2020cites this paper
• The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response

  2019influential citation
• Possible Abscopal Effect Observed in Frontal Meningioma After Localized IMRT on Posterior Meningioma Resection Cavity Without Adjuvant Immunotherapy

  2019cites this paper
• The immunological consequences of radiation‐induced DNA damage

  2019cites this paper
• Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer

  2019cites this paper
• Trends in the Abscopal Effect After Radiation to Spinal Metastases: A Systematic Review

  2019cites this paper
• Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?

  2019cites this paper
• STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

  2019cites this paper
• Revisiting Telomere Shortening in Cancer

  2019cites this paper
• EGR1 Regulates Angiogenic and Osteoclastogenic Factors in Prostate Cancer and Promotes Metastasis

  2019cites this paper
• Immune checkpoint inhibitor combinations: Current efforts and important aspects for success.

  2019cites this paper
• Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies.

  2019cites this paper
• Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system

  2019cites this paper
• Plasticity of Type I Interferon-Mediated Responses in Cancer Therapy: From Anti-tumor Immunity to Resistance

  2018cites this paper
• Gene expression profiling of rat livers after continuous whole-body exposure to low-dose rate of gamma rays

  2018cites this paper
• Distributions of manganese in diverse human cancers provide insights into tumour radioresistance.

  2018cites this paper
• Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

  2018cites this paper
• Stereotactic Body Radiotherapy: Does It Have a Role in Management of Hepatocellular Carcinoma?

  2018cites this paper
• Combination Therapy Using Ruxolitinib and Oncolytic HSV Renders Resistant MPNSTs Susceptible to Virotherapy

  2018cites this paper
• Time to abandon single-site irradiation for inducing abscopal effects

  2018cites this paper
• Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy

  2018cites this paper
• Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma

  2018cites this paper
• Discovery of Key Genes in Dermatomyositis Based on the Gene Expression Omnibus Database

  2018cites this paper
• Combination of IFITM1 knockdown and radiotherapy inhibits the growth of oral cancer

  2018cites this paper
• Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells

  2018cites this paper
• Radiotherapy as a New Player in Immuno-Oncology

  2018cites this paper
• DDX5/p68 associated lncRNA LOC284454 is differentially expressed in human cancers and modulates gene expression

  2018cites this paper
• Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?

  2018cites this paper
• Treatment of Canine Oral Melanoma with Nanotechnology-Based Immunotherapy and Radiation.

  2018cites this paper
• Comparative analysis of the effect of different radiotherapy regimes on lymphocyte and its subpopulations in breast cancer patients

  2018cites this paper
• Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation

  2017influential citation
• Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment

  2017cites this paper
• The Immunoregulatory Potential of Particle Radiation in Cancer Therapy

  2017cites this paper
• Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents

  2017cites this paper
• CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.

  2017cites this paper
• The good and the bad faces of STAT1 in solid tumours.

  2017cites this paper
• Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4

  2017cites this paper
• The synergistic effect of radiotherapy and immunotherapy: A promising but not simple partnership.

  2017cites this paper
• Radiation and Immune Checkpoint Blockade: From Bench to Clinic.

  2017cites this paper
• The Radiation Stress Response: Of the People, By the People and For the People

  2017cites this paper
• Microenvironment and Dose-Delivery-Dependent Response after Exposure to Ionizing Radiation in Human Colorectal Cancer Cell Lines

  2017cites this paper
• No role of IFITM3 in brain tumor formation in vivo

  2016cites this paper
• Radiotherapy: Changing the Game in Immunotherapy.

  2016cites this paper
• Therapeutic response in human cancers : the dual role of STAT signalling

  2016cites this paper
• Programming of Plant Leaf Senescence with Temporal and Inter-Organellar Coordination of Transcriptome in Arabidopsis1[OPEN]

  2016cites this paper
• Exploiting Gene Expression Kinetics in Conventional, Hyperfractionation, and Hypofractionation for Targeted Therapy

  2016cites this paper
• Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy.

  2016cites this paper
• Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

  2016cites this paper