The life span of naive alpha/beta T cells in secondary lymphoid organs

We have determined the life span of naive CD4-8+ T cells in T cell receptor transgenic mice. We find that such cells do not divide in secondary lymphoid organs in both normal euthymic mice and T cell- deficient mice. By both continuous labeling and by chasing pulse- labeled cells, we find that the minimum life span of the naive T cells is in the order of 8 wk.

• Publication year

  1993

• Venue

  Journal of Experimental Medicine

• Publication date

  1993-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/JEM.177.4.891PMID 8459219PMCID 2190982
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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