Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease

After the first description of fatty pancreas in 1933, the effects of pancreatic steatosis have been poorly investigated, compared with that of the liver. However, the interest of research is increasing. Fat accumulation, associated with obesity and the metabolic syndrome (MetS), has been defined as “fatty infiltration” or “nonalcoholic fatty pancreas disease” (NAFPD). The term “fatty replacement” describes a distinct phenomenon characterized by death of acinar cells and replacement by adipose tissue. Risk factors for developing NAFPD include obesity, increasing age, male sex, hypertension, dyslipidemia, alcohol and hyperferritinemia. Increasing evidence support the role of pancreatic fat in the development of type 2 diabetes mellitus, MetS, atherosclerosis, severe acute pancreatitis and even pancreatic cancer. Evidence exists that fatty pancreas could be used as the initial indicator of “ectopic fat deposition”, which is a key element of nonalcoholic fatty liver disease and/or MetS. Moreover, in patients with fatty pancreas, pancreaticoduodenectomy is associated with an increased risk of intraoperative blood loss and post-operative pancreatic fistula.

• Publication year

  2016

• Venue

  World Journal of Gastroenterology

• Publication date

  2016-09-14

• Fields of study

  Medicine

• Identifiers
  DOI 10.3748/wjg.v22.i34.7660PMID 27678349PMCID 5016366
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• International Association for the Study of Obesity

  2018cited by this paper
• Effects of berberine and cinnamic acid on palmitic acid-induced intracellular triglyceride accumulation in NIT-1 pancreatic β cells

  2016cited by this paper
• Prevalence of Pancreatic Steatosis at a Pediatric Tertiary Care Center

  2016cited by this paper
• Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas

  2016cited by this paper
• The correlation between pancreatic steatosis and metabolic syndrome in a Chinese population.

  2016cited by this paper
• Pancreatic Steatosis and Fibrosis: Quantitative Assessment with Preoperative Multiparametric MR Imaging.

  2016cited by this paper
• Betaine Attenuates Alcohol-Induced Pancreatic Steatosis

  2016cited by this paper
• Nonalcoholic fatty pancreas disease and Nonalcoholic fatty liver disease: more than ectopic fat

  2015cited by this paper
• The effects of bariatric surgery on pancreatic lipid metabolism and blood flow.

  2015cited by this paper
• Long-term High-fat High-sucrose Diet Promotes Enlarged Islets and &bgr;-Cell Damage by Oxidative Stress in Bama Minipigs

  2015cited by this paper
• MRI chemical shift imaging of the fat content of the pancreas and liver of patients with type 2 diabetes mellitus

  2015cited by this paper
• Evolution of pancreas in aging: degenerative variation or early changes of disease?

  2015cited by this paper
• Pancreatic fat and β-cell function in overweight/obese children with nonalcoholic fatty liver disease.

  2015cited by this paper
• Obesity and Fatty Pancreatic Infiltration Are Risk Factors for Pancreatic Precancerous Lesions (PanIN)

  2015cited by this paper
• Pancreatic Steatosis Demonstrated at MR Imaging in the General Population: Clinical Relevance.

  2015cited by this paper
• Quantitative analysis of pancreatic echogenicity on transabdominal sonography: Correlations with metabolic syndrome

  2015cited by this paper
• Phenotypic Characterization of Insulin-Resistant and Insulin-Sensitive Obesity.

  2015cited by this paper
• Saturation of subcutaneous adipose tissue expansion and accumulation of ectopic fat associated with metabolic dysfunction during late and post-pubertal growth

  2015cited by this paper
• Pancreatic Lipomatosis: Complete Replacement of Pancreas by Fat.

  2015cited by this paper
• Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation.

  2015cited by this paper
• Pancreatic adipose tissue infiltration, parenchymal steatosis and beta cell function in humans

  2015cited by this paper
• The effect of fatty pancreas on serum glucose parameters in patients with nonalcoholic steatohepatitis.

  2015cited by this paper
• Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and its risk factors among adult medical check-up patients in a private hospital: a large cross sectional study

  2015cited by this paper
• Non-Alcoholic Fatty Pancreas Disease Pathogenesis: A Role for Developmental Programming and Altered Circadian Rhythms

  2014cited by this paper
• Role of pancreatic fat in the outcomes of pancreatitis.

  2014cited by this paper
• Fatty Pancreas, Insulin Resistance, and β-Cell Function: A Population Study Using Fat-Water Magnetic Resonance Imaging

  2014cited by this paper
• Body Mass Index Influences the Outcome of Acute Pancreatitis: An Analysis Based on the Japanese Administrative Database

  2014cited by this paper
• The Histopathology of PRSS1 Hereditary Pancreatitis

  2014cited by this paper
• Prevalence of exocrine pancreatic insufficiency in type 2 diabetes mellitus with poor glycemic control.

  2014cited by this paper
• [Effects of octreotide on fatty infiltration of the pancreas in high-fat diet induced obesity rats].

  2014cited by this paper
• Type 2 diabetes as a disease of ectopic fat?

  2014cited by this paper
• Triglycerides in the Human Kidney Cortex: Relationship with Body Size

  2014cited by this paper
• Differences in pancreatic volume, fat content, and fat density measured by multidetector-row computed tomography according to the duration of diabetes

  2014cited by this paper
• A Comprehensive Review on Metabolic Syndrome

  2014cited by this paper
• Detection of hepatic and pancreatic fat infiltration in type II diabetes mellitus patients with IDEAL‐Quant using 3.0T MR: comparison with single‐voxel proton spectroscopy

  2014cited by this paper
• Enigmatic Ectopic Fat: Prevalence of Nonalcoholic Fatty Pancreas Disease and Its Associated Factors in a Chinese Population

  2014cited by this paper
• Initial clinical application of modified Dixon with flexible echo times: hepatic and pancreatic fat assessments in comparison with 1H MRS

  2014cited by this paper
• The association between ectopic fat in the pancreas and subclinical atherosclerosis in type 2 diabetes.

  2014cited by this paper
• Pancreatic steatosis: Is it related to either obesity or diabetes mellitus?

  2014cited by this paper
• Variable clinical presentation of Shwachman-Diamond syndrome: update from the North American Shwachman-Diamond Syndrome Registry.

  2014cited by this paper
• Association of Pancreatic Fatty Infiltration With Pancreatic Ductal Adenocarcinoma

  2014cited by this paper
• Quantitative assessment of pancreatic fat by using unenhanced CT: pathologic correlation and clinical implications.

  2014cited by this paper
• Fat, epigenome and pancreatic diseases. Interplay and common pathways from a toxic and obesogenic environment.

  2014cited by this paper
• Cystic fibrosis: unenhanced CT description of the appendix in asymptomatic adults.

  2014cited by this paper
• Pancreatic Fat Accumulation, Fibrosis, and Acinar Cell Injury in the Zucker Diabetic Fatty Rat Fed a Chronic High-Fat Diet

  2014cited by this paper
• Ectopic fat storage in the pancreas using 1H-MRS: importance of diabetic status and modulation with bariatric surgery-induced weight loss

  2014cited by this paper
• Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome.

  2014cited by this paper
• [Effect of jiaotai pill on pancreatic fat accumulation and islet cell apoptosis in rats with type 2 diabetes].

  2014cited by this paper
• Automatic intra‐subject registration‐based segmentation of abdominal fat from water–fat MRI

  2013cited by this paper
• Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls

  2013cited by this paper
• The Association between Nonalcoholic Fatty Pancreas Disease and Diabetes

  2013cited by this paper
• Predictive parameters of intraoperative blood loss in patients who underwent pancreatectomy.

  2013cited by this paper
• Association between non-alcoholic fatty pancreatic disease (nafpd) and the metabolic syndrome: case–control retrospective study

  2013cited by this paper
• Increased oxidative stress in obesity: implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer.

  2013cited by this paper
• [Risk factors for hyperechogenic páncreas in ecoendoscopy: study of cases and controls].

  2013cited by this paper
• Pre-operative prediction of pancreatic fistula: is it possible?

  2013cited by this paper
• Association between novel MRI‐estimated pancreatic fat and liver histology‐determined steatosis and fibrosis in non‐alcoholic fatty liver disease

  2013cited by this paper
• Fibrosis reduces severity of acute-on-chronic pancreatitis in humans.

  2013cited by this paper
• Ectopic fat deposition in prediabetic overweight and obese minority adolescents.

  2013cited by this paper
• Abdominal and Total Adiposity and The Risk of Acute Pancreatitis: A Population-Based Prospective Cohort Study

  2013cited by this paper
• Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice

  2012cited by this paper
• Increased Pancreatic Fat Fraction Is Present in Obese Adolescents With Metabolic Syndrome

  2012cited by this paper
• Preoperative CT Scan Helps to Predict the Occurrence of Severe Pancreatic Fistula After Pancreaticoduodenectomy

  2012cited by this paper
• Pancreatic lipomatosis with massive steatorrhea.

  2012cited by this paper
• Expression of the adipocytokine resistin and its association with the clinicopathological features and prognosis of pancreatic ductal adenocarcinoma.

  2012cited by this paper
• Pancreatic Steatosis and Its Relationship to β-Cell Dysfunction in Humans

  2012cited by this paper
• Pancreatic Steatosis and Its Relationship to b-Cell Dysfunction in Humans Racial and ethnic variations

  2012cited by this paper
• Spleen-Derived Interleukin-10 Downregulates the Severity of High-Fat Diet-Induced Non-Alcoholic Fatty Pancreas Disease

  2012cited by this paper
• Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies.

  2012cited by this paper
• [Pancreatic hyperenzymemia: new advances in the field of clinical-diagnostic approach, with particular attention about Gullo's syndrome].

  2012cited by this paper
• National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants.

  2011cited by this paper
• The clinical significance of pancreatic steatosis

  2011cited by this paper
• A prospective evaluation of fatty pancreas by using EUS.

  2011cited by this paper
• Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY)

  2011cited by this paper
• Global status report on noncommunicable diseases 2010.

  2011cited by this paper
• Effect of Different Obesogenic Diets on Pancreatic Histology in Ossabaw Miniature Swine

  2011cited by this paper
• Enhancement of Carcinogenesis and Fatty Infiltration in the Pancreas in N-Nitrosobis(2-Oxopropyl)Amine-Treated Hamsters by High-Fat Diet

  2011cited by this paper
• Evaluating steatosis in pancreatic transplant.

  2011cited by this paper
• Pancreatic hyperechogenicity on endoscopic ultrasound examination.

  2011cited by this paper
• Preoperative computed tomography measurements of pancreatic steatosis and visceral fat: prognostic markers for dissemination and lethality of pancreatic adenocarcinoma.

  2011cited by this paper
• Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity.

  2011cited by this paper
• Pancreatic Ultrastructural Enhancement Due to Telmisartan Plus Sitagliptin Treatment in Diet-Induced Obese C57BL/6 Mice

  2011cited by this paper
• Ectopic fat storage in the pancreas, liver, and abdominal fat depots: impact on β-cell function in individuals with impaired glucose metabolism.

  2011cited by this paper
• Ethnic Differences in Pancreatic Fat Accumulation and Its Relationship With Other Fat Depots and Inflammatory Markers

  2011cited by this paper
• Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pancreatitis in Obesity

  2011cited by this paper
• Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis

  2011cited by this paper
• Smoking Is Related to Pancreatic Fibrosis in Humans

  2011cited by this paper
• Total pancreatic lipomatosis with malabsorption syndrome

  2011cited by this paper
• Histomorphological Features of the Pancreatic Remnant as Independent Risk Factors for Postoperative Pancreatic Fistula: A Matched-Pairs Analysis

  2011cited by this paper
• Pancreatic fat accumulation and its relationship with liver fat content and other fat depots in obese individuals

  2011cited by this paper
• Lipomatous Pseudohypertrophy of the Pancreas: A Clinicopathologically Distinct Entity

  2010cited by this paper
• Fat replacement of the malignant pancreatic tissue after neoadjuvant therapy

  2010cited by this paper
• Nonalcoholic Fatty Liver Disease Is Related to Nonalcoholic Fatty Pancreas Disease

  2010cited by this paper
• Measurement of Pancreatic Fat by Magnetic Resonance Imaging: Predicting the Occurrence of Pancreatic Fistula After Pancreatoduodenectomy

  2010cited by this paper
• Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomy.

  2010cited by this paper
• Maternal obesity programmes offspring development of non-alcoholic fatty pancreas disease

  2010cited by this paper
• Pancreatic steatosis: harbinger of type 2 diabetes in obese rodents

  2010cited by this paper
• Associated factors for a hyperechogenic pancreas on endoscopic ultrasound.

  2010cited by this paper
• Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study

  2010cited by this paper
• Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan).

  2010cited by this paper

• International Multidisciplinary Consensus Report on Definitions, Diagnostic Criteria, and Management of Fatty Pancreas: A Joint Statement Endorsed by EPC, APA, EASD, EASL, ESGAR, ESGE, ESP, ESPCG, ESPEN, ESPGHAN, IAP, JPS, KPBA, LAPSG, and UEG

  2026cites this paper
• Metabolic Syndrome and Non-alcoholic Fatty Pancreas Disease

  2025cites this paper
• The association between pancreatic diseases and pancreatic fat content: a cross-sectional study from the UK Biobank

  2025cites this paper
• Imaging of Aging Pancreas

  2025cites this paper
• Quantification of ectopic fat fractions in type 2 diabetes mellitus using MR-dixon technique

  2025cites this paper
• Impact of pancreatic steatosis on risk of Post-ERCP pancreatitis: Systematic review and meta-analysis.

  2025cites this paper
• Significance of Pancreatic Steatosis as a Predictor of New-onset Diabetes Mellitus Following Pancreatectomy

  2025cites this paper
• Pancreatic changes in patients with visceral fat obesity: an evaluation with contrast-enhanced dual-energy computed tomography with automated three-dimensional volumetry

  2025influential citation
• Construction of a nomogram for hypertriglyceridemic severe acute pancreatitis that includes metabolic indexes

  2025influential citation
• Clinical Outcomes of Acute Pancreatitis in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): A Systematic Review and Meta-Analysis

  2025cites this paper
• Correlation Between Fatty Pancreas and Coronary Artery Calcium Score in a Dyslipidemic Population

  2025cites this paper
• Ultrasound innovations in abdominal radiology: techniques and clinical applications in pediatric imaging

  2024cites this paper
• High prevalence of pancreatic steatosis in pancreatic cancer patients: A meta-analysis and systematic review.

  2024cites this paper
• Developmental programming: Testosterone excess masculinizes female pancreatic transcriptome and function in sheep.

  2024cites this paper
• Consumption of interesterified palm oil leads inflammation of white adipose tissue and triggers metabolic disturbances in mice on a high-fat diet

  2024cites this paper
• Reduced Branched-Chain Amino Acid Intake Improved High-Fat Diet-Induced Nonalcoholic Fatty Pancreas Disease in Mice

  2024cites this paper
• Pathophysiological Mechanisms and Clinical Associations of Non-Alcoholic Fatty Pancreas Disease

  2024influential citation
• Uric Acid Inhibits Mice Pancreatic Steatosis via the Glycerophospholipid Pathway

  2024cites this paper
• Cross-sectional imaging of the pancreas in diabetes

  2024cites this paper
• Evaluation of pancreatic iodine uptake and related influential factors in multiphase dual-energy CT

  2024cites this paper
• Predictive value of anthropometric and biochemical indices in non-alcoholic fatty pancreas disease: a cross-sectional study

  2024cites this paper
• Effect of uric acid on lipid metabolism assessed via restricted cubic splines: A new insight

  2024cites this paper
• Non-invasive diagnosis of pancreatic steatosis with ultrasound images using deep learning network

  2024cites this paper
• Association of Insulin Resistance and Ectopic Fat Accumulation with HOMA Indices: A Single-Centre Observational Study

  2024cites this paper
• Extended Review and Updates of Nonalcoholic Fatty Pancreas Disease

  2024influential citation
• Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review

  2023cites this paper
• Pancreatic fat in type 2 diabetes: Causal or coincidental?

  2023cites this paper
• Pancreatic steatosis and its correlation with clinicopathological features in patients with pancreatic neuroendocrine neoplasms

  2023cites this paper
• Intrapancreatic fat deposition and nutritional treatment: the role of various dietary approaches.

  2023cites this paper
• Nonalcoholic Fatty Pancreas Disease

  2023cites this paper
• Optimized nucleus isolation protocol from frozen mouse tissues for single nucleus RNA sequencing application

  2023cites this paper
• Relationship of Liver Blood Tests and T1 Relaxation Time With Intra-pancreatic Fat Deposition

  2023cites this paper
• Fatty infiltration of the pancreas: a systematic concept analysis

  2023cites this paper
• Non-alcoholic fatty pancreas disease: an updated review

  2023cites this paper
• Circulatory miRNAs as Correlates of Elevated Intra-Pancreatic Fat Deposition in a Mixed Ethnic Female Cohort: The TOFI_Asia Study

  2023cites this paper
• Intrapancreatic fat, pancreatitis, and pancreatic cancer

  2023cites this paper
• CT imaging shows specific pancreatic abnormalities in persons with cystic fibrosis related diabetes

  2023cites this paper
• Pancreatic changes with lifestyle and age: What is normal and what is concerning?

  2023cites this paper
• Increased Incidence of Pancreatic Steatosis Detected Using Computed Tomography at Initial Diagnosis of Coronavirus Disease 2019

  2023cites this paper
• Non-Alcoholic Fatty Pancreas Disease: The Unsung Disease.

  2022cites this paper
• High Triglyceride–Glucose Index Is Associated with Poor Prognosis in Patients with Acute Pancreatitis

  2022cites this paper
• Obesity and Pancreatic Cancer: Recent Progress in Epidemiology, Mechanisms and Bariatric Surgery

  2022cites this paper
• Fatty Pancreas-Centered Metabolic Basis of Pancreatic Adenocarcinoma: From Obesity, Diabetes and Pancreatitis to Oncogenesis

  2022influential citation
• Ensemble Convolutional Neural Network Classification for Pancreatic Steatosis Assessment in Biopsy Images

  2022cites this paper
• Magnetic Resonance Imaging Assessment of Abdominal Ectopic Fat Deposition in Correlation With Cardiometabolic Risk Factors

  2022cites this paper
• Clinical Significance of Pancreatic Fat in Children

  2022cites this paper
• Pancreas fat content, insulin homeostasis and circulating endothelial microparticles in male essential hypertensive patients

  2022cites this paper
• A nem alkoholos hasnyálmirigy-elzsírosodás klinikai jelentősége.

  2022cites this paper
• Design and Rationale for the Use of Magnetic Resonance Imaging Biomarkers to Predict Diabetes After Acute Pancreatitis in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.

  2022cites this paper
• Non-alcoholic Fatty Liver Disease and Steatohepatitis: Risk Factors and Pathophysiology

  2022cites this paper
• Multi-frequency magnetic resonance elastography of the pancreas: measurement reproducibility and variance among healthy volunteers

  2022cites this paper
• Combined effect of pancreatic lipid content and gene variants (TCF7L2, WFS1 and 11BHSD1) on B-cell function in Middle Aged Women in a Post Hoc Analysis

  2022cites this paper
• Effects of body fat components on early renal functions of individuals following kidney donation

  2022cites this paper
• Ectopic fat deposition and its related abnormalities of lipid metabolism followed by nonalcoholic fatty pancreas

  2022cites this paper
• Automated image analysis method to detect and quantify fat cell infiltration in hematoxylin and eosin stained human pancreas histology images

  2021cites this paper
• Aerobic training reduces pancreatic fat content and improves β‐cell function: A randomized controlled trial using IDEAL‐IQ magnetic resonance imaging

  2021cites this paper
• Nonalcoholic Fatty Pancreas Disease: Role in Metabolic Syndrome, “Prediabetes,” Diabetes and Atherosclerosis

  2021cites this paper
• Microbiota in Pancreatic Diseases: A Review of the Literature

  2021influential citation
• Quantitative Analysis of Pancreatic Fat in Children with Obesity Using Magnetic Resonance Imaging and Ultrasonography

  2021cites this paper
• Association of Incidence between Pancreatic Adipose Infiltration and Metabolic Syndrome: A Literature Review and Meta-analysis

  2021cites this paper
• Fatty Pancreas Represents a Risk Factor for Acute Pancreatitis

  2021cites this paper
• Nonalcoholic fatty pancreas disease: An emerging clinical challenge

  2021cites this paper
• Pancreatic steatosis in adult rats induced by nicotine exposure during breastfeeding

  2021influential citation
• Effect of pioglitazone on the expression of ubiquitin proteasome system and autophagic proteins in rat pancreas with metabolic syndrome

  2021cites this paper
• Quantitative MRI Assessment of Pancreatic Steatosis Using Proton Density Fat Fraction in Pediatric Obesity

  2021cites this paper
• Recommendations for the Management of Incidental Pancreatic Findings in Adults by the Canadian Association of Radiologists Incidental Findings Working Group

  2021cites this paper
• Does Nonalcoholic Pancreatic Steatosis Always Correlate with Nonalcoholic Fatty Liver Disease?

  2021cites this paper
• Identification of “Digital Sarcopenia” Can Aid the Detection of Pancreatic Exocrine Insufficiency and Malnutrition Assessment in Patients with Suspected Pancreatic Pathology

  2021cites this paper
• Evaluating Pancreatic index in Patients with and without Metabolic Syndrome

  2021cites this paper
• The importance of vaspin in external and internal secretory activity of the pancreas

  2021cites this paper
• Do we really need nutraceutical liver support? Experimental effectiveness, risks and proven clinical benefits

  2021cites this paper
• Fatty Pancreas: Clinical Implications

  2021cites this paper
• Triglycerides to high-density lipoprotein cholesterol ratio for diagnosing nonalcoholic fatty liver disease.

  2021cites this paper
• Severity of hyperechoic pancreas on ultrasonography as a risk factor for glycemic progression

  2021cites this paper
• Does Nonalcoholic Pancreatic Steatosis Always Correlate with Nonalcoholic Fatty Liver Disease?

  2021cites this paper
• Fatty Pancreas: An Underappreciated Intersection of the Metabolic Profile and Pancreatic Adenocarcinoma

  2021cites this paper
• The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates

  2021cites this paper
• Pancreatic and hepatobiliary manifestations of nonalcoholic fatty pancreatic disease: a referral multi-center experience

  2021cites this paper
• Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism

  2021cites this paper
• Morpho-functional state of rat pancreas under melatonin administration during obesity development: chronotherapeutic approach

  2020cites this paper
• Curcuma supplementation in high-fat-fed C57BL/6 mice: no beneficial effect on lipid and glucose profile or prevention of weight gain

  2020cites this paper
• Connecting pancreatic islet lipid metabolism with insulin secretion and the development of type 2 diabetes

  2020cites this paper
• Hepatic and pancreatic fat as imaging biomarkers of metabolic syndrome.

  2020cites this paper
• The correlation between the MRI-evaluated ectopic fat accumulation and the incidence of diabetes mellitus and hypertension depends on body mass index and waist circumference ratio

  2020cites this paper
• Pancreatic fat accumulation evaluated by multidetector computed tomography in patients with type 2 diabetes

  2020cites this paper
• Decreased CT-number in the pancreatic parenchyma is a reliable imaging biomarker of the presence of malignancies in patients with high-risk intraductal papillary mucinous neoplasm.

  2020cites this paper
• Hepatic and pancreatic fat as imaging biomarkers of metabolic syndrome

  2020cites this paper
• Dysregulation of miR-192-5p in acute pancreatitis patients with nonalcoholic fatty liver and its functional role in acute pancreatitis progression

  2020cites this paper
• Titan Mice are Unique Short-Lived mammalian model of metabolic syndrome and aging

  2020influential citation
• The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives

  2020cites this paper
• Pancreatic Fat Infiltration Is Associated with a Higher Risk of Pancreatic Ductal Adenocarcinoma

  2020cites this paper
• Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?

  2020cites this paper
• Non-alcoholic fatty liver disease: correlation with hyperuricemia in a European Mediterranean population

  2020cites this paper
• What is the role of measuring shear wave dispersion using shear wave elastography in pancreatic parenchyma?

  2020cites this paper
• Pancreatic Fat is not significantly correlated with β-cell Dysfunction in Patients with new-onset Type 2 Diabetes Mellitus using quantitative Computed Tomography

  2020cites this paper
• Detection of Lipase Activity in Cells by a Fluorescent Probe Based on Formation of Self-Assembled Micelles

  2020cites this paper
• Evaluation of Ethnic Variations in Visceral, Subcutaneous, Intra-Pancreatic, and Intra-Hepatic Fat Depositions by Magnetic Resonance Imaging among New Zealanders

  2020cites this paper
• The Role of Dysfunctional Adipose Tissue in Pancreatic Cancer: A Molecular Perspective

  2020cites this paper
• Environmental Factors Slightly Outweigh Genetic Influences in the Development of Pancreatic Lipid Accumulation: A Classical Twin Study

  2020cites this paper
• Patients with type 2 diabetes present with multiple anomalies of the pancreatic arterial tree on abdominal computed tomography: comparison between patients with type 2 diabetes and a matched control group

  2020cites this paper