Barrier to autointegration factor (BAF) is an essential mobile protein that binds lamins, LEM-domain proteins, histones, and DNA. Under environmental stress, BAF becomes immobile. This phenomenon is not shared with other chromatin-binding proteins. The ability of BAF mutants to be immobilized by heat shock in gut cells correlated with normal or increased affinity for emerin.
BAF-1 mobility is regulated by environmental stresses
D. Bar,M. Davidovich,Ayelet T. Lamm,H. Zer,K. Wilson,Y. Gruenbaum
Published 2014 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2014
- Venue
Molecular Biology of the Cell
- Publication date
2014-04-01
- Fields of study
Biology, Medicine, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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