Sympathetic Activation by Sildenafil

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Circulation

• Publication date

  2000-12-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.CIR.102.25.3068PMID 11120696
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sympathetic activation by sildenafil.

  2001cited by this paper
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• Immunohistochemical Localization of cGMP-binding cGMP-specific Phosphodiesterase (PDE5) in Rat Tissues

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• Management of sexual dysfunction in patients with cardiovascular disease: recommendations of the Princeton Consensus Panel.

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• Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure.

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• Hemodynamic effects of sildenafil in men with severe coronary artery disease.

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• Molecular typing of Mycobacterium tuberculosis.

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• Subaortic obstruction after sildenafil in a patient with hypertrophic cardiomyopathy.

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• Effects of sildenafil citrate on human hemodynamics.

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• ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association.

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• Retinal side-effects of sildenafil.

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• Retinal side-effects of sildenafil.

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• Use of sildenafil (Viagra) in patients with cardiovascular disease. Technology and Practice Executive Committee.

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• Acute myocardial infarction after the use of sildenafil.

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• Clinical safety of oral sildenafil citrate (VIAGRATM) in the treatment of erectile dysfunction

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• EFFICACY AND SAFETY OF ORAL SILDENAFIL IN THE TREATMENT OF ERECTILE DYSFUNCTION: A DOUBLE‐BLIND, PLACEBO‐CONTROLLED STUDY OF 329 PATIENTS

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• Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase.

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• Differential effects of captopril and nitrates on muscle sympathetic nerve activity in volunteers.

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• Preeclampsia - a state of sympathetic overactivity.

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• Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.

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• Triggering myocardial infarction by sexual activity. Low absolute risk and prevention by regular physical exertion. Determinants of Myocardial Infarction Onset Study Investigators.

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• Preeclampsia -- a state of sympathetic overactivity.

  1996cited by this paper
• Triggering Myocardial Infarction by Sexual Activity: Low Absolute Risk and Prevention by Regular Physical Exertion

  1996cited by this paper
• TRIGGERING MYOCARDIAL INFARCTION BY SEXUAL ACTIVITY : LOW ABSOLUTE RISK AND PREVENTION BY REGULAR PHYSICAL EXERTION

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• Clinical and hemodynamic correlates of sympathetic nerve activity in normal humans and patients with heart failure: evidence from direct microneurographic recordings.

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• Cyclosporine-induced sympathetic activation and hypertension after heart transplantation.

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• Clinical and hemodynamic correlates of sympathetic nerve activity in normal humans and patients with heart failure: Evidence from direct micronenrographic recordings

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• Evaluation of erectile impotence.

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• Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure.

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• Phosphodiesterase inhibition restores hypoxia-induced cerebrovascular dysfunction subsequent to improved systemic redox homeostasis: A randomized, double-blind, placebo-controlled crossover study

  2025influential citation
• PDE-5 INHIBITION MITIGATES MENTAL STRESS-INDUCED ENDOTHELIAL DYSFUNCTION IN RESISTANT HYPERTENSION.

  2025cites this paper
• Detection of sildenafil and its 9 metabolites in a post-race horse urine sample: A case report.

  2024cites this paper
• Retinal Nerve Fibre Layer, Macular and Choroidal Thickness in Erectile Dysfunction Patients on Sildenafil

  2024cites this paper
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  2023cites this paper
• Etiologies and Mechanisms of Ischemic Stroke Associated with Sexual Intercourse: A Literature Review

  2021cites this paper
• Clinical Outcomes of Sildenafil Application in Patients of Poor Endometrial Development

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• Sildenafil in Ophthalmology: An update.

  2021cites this paper
• Combined Intravenous Sildenafil and l-Arginine Administration in a Porcine Animal Model: Hemodynamic Safety Profile and Effects on Coronary Blood Flow

  2020cites this paper
• Sildenafil does not reliably improve exercise performance in hypoxia: a systematic review

  2019cites this paper
• Toxic Effects of Sexual Drug Overdose: Sildenafil (Viagra)

  2019cites this paper
• Exercise Training Plus Sildenafil Treatment: Role on Autonomic and Inflammatory Markers

  2018influential citation
• Sildenafil induces browning of subcutaneous white adipose tissue in overweight adults.

  2018cites this paper
• The impact of sildenafil citrate on neurotransmitter amino acids levels in brain tissue of albino rat.

  2018cites this paper
• The impact of sildenafil citrate on neurotransmitter amino acid levels in brain tissue of albino rats

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• Use of &bgr;-Blockers in Pulmonary Hypertension

  2017cites this paper
• Neuroprotective effects of sildenafil against oxidative stress and memory dysfunction in mice exposed to noise stress

  2017cites this paper
• Are Erectile Dysfunction Medications Causally Related to Nonarteritic Anterior Ischemic Optic Neuropathy?

  2016cites this paper
• Novel Therapeutic Targets for Phosphodiesterase 5 Inhibitors: current state-of-the-art on systemic arterial hypertension and atherosclerosis.

  2016cites this paper
• Effect of Sildenafil on Pancreatic Epidermal Growth Factor Expression and β-cell Function

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• Role of Phosphodiesterase 5 and Cyclic GMP in Hypertension

  2016cites this paper
• Potentiation of the NO-cGMP pathway and blood flow responses during dynamic exercise in healthy humans

  2016cites this paper
• Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes

  2015cites this paper
• Impaired Neuronal Nitric Oxide Synthase–Mediated Vasodilator Responses to Mental Stress in Essential Hypertension

  2015cites this paper
• Polymorphism of the G protein β3 subunit gene influences the efficacy of sildenafil in patients with pulmonary hypertension.

  2014cites this paper
• Sympathoneural and adrenomedullary responses to mental stress.

  2014cites this paper
• Sidenafil Pre-Treatment Promotes Decompression Sickness in Rats

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• The Possible Cardiopulmonary and Cerebral Toxic Effects of Sildenafil Citrate (Viagra) on Adult Male Albino Rats

  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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• The phosphodiesterases type 5 inhibitor tadalafil reduces the activation of the hypothalamus-pituitary-adrenal axis in men during cycle ergometric exercise.

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• phosphodiesterase-5 inhibition in awake swine at rest and during treadmill exercise Endothelial dysfunction enhances the pulmonary and systemic vasodilator effects of

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• Pathogenesis of Some Controversial Non-arteritic Anterior Ischemic Optic Neuropathy Clinical Entities

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• Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration

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• Effects of phosphodiesterase type 5 inhibitors on endothelial function and cardiovascular autonomic nerve function in men

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• Czy jest miejsce na terapię inhibitorami fosfodiesterazy typu 5 u chorych z niewydolnością serca? Is there a place for treatment with type 5 phosphodiesterase inhibitors in heart failure patients?

  2011cites this paper
• Nicht-invasive Messung hämodynamischer Parameter bei Patienten mit pulmonalarterieller Hypertonie unter Belastung

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• [Is there a place for treatment with type 5 phosphodiesterase inhibitors in heart failure patients?].

  2011cites this paper
• Subarachnoid hemorrhage during sexual activity after sildenafil intake: an accidental association?

  2011cites this paper
• Sildenafil counteracts the inhibitory effect of social subordination on competitive aggression and sexual motivation in male mice.

  2011cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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• [Clinical use of phosphodiesterase-5 inhibitors in cardiopulmonary diseases: from experimental evidence to clinical application].

  2009cites this paper
• Sildenafil increases the force of right atrial contractions in vitro via the NO-guanylyl cyclase pathway involving β-adrenoceptor linked mechanisms

  2009cites this paper
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  2008cites this paper
• An Open-Label Pilot Study to Evaluate the Efficacy of Sildenafil Citrate in Middle-Aged Men With Late-Onset Dysthymia

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• Sildenafil delays the intestinal transit of a liquid meal in awake rats.

  2008cites this paper
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  2008influential citation
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  2008cites this paper
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• Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility

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• Effect of Sildenafil on Reperfusion Function, Infarct Size, and Cyclic Nucleotide Levels in the Isolated Rat Heart Model

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• Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites.

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• Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans.

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• Sildenafil Inhibits β-Adrenergic–Stimulated Cardiac Contractility in Humans

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• Inhibition of angiotensin-converting enzyme and phosphodiesterase type 5 improves endothelial function in heart failure.

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• Aggressive behavior increases after termination of chronic sildenafil treatment in mice.

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• Genpolymorphismen und erektile Dysfunktion

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