Muscle Relaxants for Nonspecific Low Back Pain: A Systematic Review Within the Framework of the Cochrane Collaboration

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Spine

• Publication date

  2003-09-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/01.BRS.0000090503.38830.ADPMID 12973146
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The medical management of spasticity.

  2002cited by this paper
• Many faces of the minimal clinically important difference (MCID): a literature review and directions for future research.

  2002cited by this paper
• Reliability and validity of a visual analog scale for acute abdominal pain in the ED.

  2002cited by this paper
• Treatment of spasticity

  2002cited by this paper
• Cyclobenzaprine and back pain: a meta-analysis.

  2001cited by this paper
• Cyclobenzaprine hydrochloride is a commonly prescribed centrally acting muscle relaxant, which is structurally similar to tricyclic antidepressants (TCAs) and differs from amitriptyline by only one double bond.

  2001cited by this paper
• Clinical Guidelines for the Management of Low Back Pain in Primary Care: An International Comparison

  2001cited by this paper
• Clinical importance of changes in chronic pain intensity measured on an 11‐point numerical pain rating scale

  2001cited by this paper
• Nevirapine and the risk of Stevens–Johnson syndrome or toxic epidermal necrolysis

  2001cited by this paper
• A survey of primary care physician practice patterns and adherence to acute low back problem guidelines.

  2000cited by this paper
• Interpretation of quality-of-life outcomes: issues that affect magnitude and meaning.

  2000cited by this paper
• Defining the clinically important difference in pain outcome measures

  2000cited by this paper
• Agency for Health Care Policy and Research.

  1999cited by this paper
• Controlled trial of cyclobenzaprine for acute musculoskeletal spasm

  1999cited by this paper
• Medication Use for Low Back Pain in Primary Care

  1998cited by this paper
• (1996) Low Back Pain Evidence Review London: Royal College of General Practitioners

  1998cited by this paper
• Conservative Treatment of Acute and Chronic Nonspecific Low Back Pain: A Systematic Review of Randomized Controlled Trials of the Most Common Interventions

  1997cited by this paper
• Method guidelines for systematic reviews in the Cochrane Collaboration Back Review Group for Spinal Disorders.

  1997cited by this paper
• Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.

  1996cited by this paper
• Efficacy and tolerance of repeated oral doses of tolperisone hydrochloride in the treatment of painful reflex muscle spasm: results of a prospective placebo‐controlled double‐blind trial

  1996cited by this paper
• NHG-standaard Lage-Rugpijn

  1996cited by this paper
• Identifying relevant studies for systematic reviews

  1995cited by this paper
• [Anterior pituitary failure in the post-partum period and autoimmune thyroiditis: pituitary necrosis or hypophysitis?].

  1995cited by this paper
• Identifying relevant studies for systematic reviews.

  1994cited by this paper
• Systematic Reviews: Identifying relevant studies for systematic reviews

  1994cited by this paper
• [The efficacy of sirdalud in the drug therapy of pain in the spine].

  1994cited by this paper
• Carisoprodol (Soma): A New and Cautious Perspective on an Old Agent

  1993cited by this paper
• Treatment of chronic low-back syndrome with tetrazepam in a placebo controlled double-blind trial

  1992cited by this paper
• Intérêt de la pommade SRILANE® dans le traitement symptomatique des lombalgies chroniques: étude en double aveugle contre placebo

  1991cited by this paper
• Abuse of skeletal muscle relaxants.

  1991cited by this paper
• [Evaluation of thiocolchicoside as monotherapy in low back pain. Results of a randomized study versus placebo].

  1990cited by this paper
• [Clinical double-blind study with idrocilamide ointment in the treatment of acute lumbago].

  1990cited by this paper
• Cyclobenzaprine and naproxen versus naproxen alone in the treatment of acute low back pain and muscle spasm.

  1990cited by this paper
• The myth of skeletal muscle spasm.

  1989cited by this paper
• The myth of skeletal muscle spasm.

  1989cited by this paper
• Acute Back Pain and Spasm: A Controlled Multicenter Trial of Combined Analgesic and Antispasm Agents

  1989cited by this paper
• Estudio DS 103-282: Relajante Muscular en Lumbalgia Aguda o Lumbago: (estudio doble ciego de Tizanidina + Paracetamol V s Placebo + Paracetamol)

  1989cited by this paper
• Acute Low Back Pain: Symptomatic Treatment with a Muscle Relaxant Drug

  1988cited by this paper
• Tizanidine and Ibuprofen in Acute Low-Back Pain: Results of a Double-Blind Multicentre Study in General Practice

  1988cited by this paper
• A Multicentre Placebo-Controlled Study in General Practice to Evaluate the Efficacy and Safety of Tizanidine in Acute Low-Back Pain

  1988cited by this paper
• Intravenous orphenadrine for the treatment of lumbar paravertebral muscle strain

  1988cited by this paper
• Mefenamic acid, chlormezanone‐paracetamol, ethoheptazine‐aspirin‐meprobamate: a comparative study in acute low back pain

  1987cited by this paper
• Reference bias in reports of drug trials.

  1987cited by this paper
• Baclofen for the Treatment of Acute Low-Back Syndrome: A Double-Blind Comparison with Placebo

  1985cited by this paper
• A Comparison of Two Analgesic Muscle Relaxant Combinations in Acute Back Pain

  1984cited by this paper
• A comparison of two analgesic muscle relaxant combinations in acute back pain.

  1984cited by this paper
• Chlormezanone in Low Back Pain and Wry Neck—an “Analgesic Sparing” Effect

  1984cited by this paper
• A Double-Blind Comparison in General Practice of a Combination Tablet Containing Orphenadrine Citrate and Paracetamol (‘Norgesic') with Paracetamol Alone

  1983cited by this paper
• Management of acute musculoskeletal conditions. Thoracolumbar strain or sprain: A double-blind evaluation comparing the efficacy and safety or carisoprodol with cyclobenzaprine hydrochloride

  1983cited by this paper
• Tizanidine (DS 103-282) in the Treatment of Acute Paravertebral Muscle Spasm: A Controlled Trial Comparing Tizanidine and Diazepam

  1981cited by this paper
• A New Skeletal Muscle Relaxant (DS 103-282*) Compared to Diazepam in the Treatment of Muscle Spasm of Local Origin

  1981cited by this paper
• Centrally acting oral skeletal muscle relaxants.

  1980cited by this paper
• Comparison of the effect of diazepam and levomepromazine on pain in patients with acute lumbago-sciatica.

  1980cited by this paper
• Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical and laboratory studies.

  1978influential reference
• Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical and laboratory studies.

  1978cited by this paper
• Cyclobenzaprine in intractable pain syndromes with muscle spasm.

  1978cited by this paper
• A Controlled Clinical Trial of a Muscle Relaxant Analgesic Combination in the Treatment of Acute Lumbago

  1976influential reference
• A double-blind trial of methocarbamol versus placebo in painful muscle spasm.

  1975cited by this paper
• [Therapy of acute lumbovertebral syndromes through optimal muscle relaxation using diazepam. Results of a double-blind study on 68 cases].

  1973cited by this paper
• Zur Therapie akuter lumbovertebraler Syndrome durch optimale medikamentöse Muskelrelaxation mittels Diazepam.

  1973influential reference
• Comparison of carisoprodol, butabarbital, and placebo in treatment of the low back syndrome.

  1972cited by this paper
• A double-blind evaluation of Parafon Forte in the treatment of musculo-skeletal back conditions.

  1972cited by this paper
• A double-blind evaluation of Parafon Forte in the treatment of musculo-skeletal back conditions.

  1972cited by this paper
• Orphenadrin-paracetamol in backache-a double-blind controlled trial.

  1971cited by this paper
• A Double‐blind Comparative Trial of ‘Parazolidin’ and Paracetamol

  1969cited by this paper
• [Polycentric clinical trials of a muscle relaxant].

  1968cited by this paper
• Treatment of spasticity.

  1967cited by this paper
• Diazepam in backache. A double-blind controlled trial.

  1966influential reference

• [Contemporary concepts of the rational use of centrally acting skeletal muscle relaxants in the treatment of vertebrogenic dorsalgia].

  2025cites this paper
• The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for a Randomised Clinical Trial

  2025cites this paper
• Trends in the use of opioid and non-opioid analgesics after TBI with and without polytrauma

  2025cites this paper
• Effect of a Healing Program Using Marine Resources on Reducing Pain and Improving Physical Function in Patients with Non-Specific Chronic Low Back Pain: A Randomized Controlled Trial Study

  2025cites this paper
• Evaluation of the advantages of orphenadrine in anaesthesia caused by ketamine in mice

  2024cites this paper
• Akuter Rückenschmerz

  2024cites this paper
• Long-Term Use of Muscle Relaxant Medications for Chronic Pain

  2024cites this paper
• What a pain in the … back: a review of current treatment options with a focus on naproxen sodium

  2024cites this paper
• Efficiency of physical therapy and osteopathic techniques in the treatment of operated and recurrent lumbar disc herniation - A case report.

  2024cites this paper
• Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees

  2024cites this paper
• [The role of structure-modifying agents in the treatment of back pain].

  2023cites this paper
• Does adding muscle relaxant make post-operative pain better? a narrative review of the literature from US and European studies

  2023cites this paper
• The effects of immersion in 42℃ radon, natrium, calcium, bicarbonate content thermal-mineral water on chronic low back pain. Controlled, follow-up study

  2023cites this paper
• Multiple traditional Chinese medicinal approaches in collaboration with conservative conventional medicine for lumbar herniated intervertebral discs: A systematic review and meta-analysis

  2023cites this paper
• Evidence-Based Orthopaedic Post-Operative Opioid Prescribing Recommendations Following Spine Surgery

  2023cites this paper
• Comparison of the Efficiency and Safety of Oral Phenyramidol and Phenyramidol+Diclofenac Treatment in Muscle Spasms with Spinal Pain – Open-Label Study

  2022cites this paper
• Tizanidine: An overlooked alternative muscle relaxant for older patients

  2022cites this paper
• Benzodiazepines and Related Drugs in Orthopaedics

  2022cites this paper
• Non-operative treatment for low back pain: A review of evidence and recommendations.

  2022cites this paper
• The Relative Efficacy of Seven Skeletal Muscle Relaxants. An Analysis of Data From Randomized Studies.

  2022cites this paper
• Analysis of Scoliosis-related Medical Services in South Korea Between 2010 and 2018

  2022cites this paper
• Non-Surgical Interventions for Lumbar Spinal Stenosis Leading To Neurogenic Claudication: A Clinical practice guideline.

  2021cites this paper
• Pain reliever combinations in treatment of patients with acute musculoskeletal back pain

  2021cites this paper
• Prescribing Patterns of Pain Medications in Unspecific Low Back Pain in Primary Care: A Retrospective Analysis

  2021cites this paper
• Faset sendromu olan osteoporotik hastalarda pulse radyofrekans yönteminin etkinliğinin değerlendirilmesi

  2021cites this paper
• Preoperative pain neurophysiology education for lumbar radiculopathy: A randomized-controlled trial

  2021cites this paper
• Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review.

  2021cites this paper
• Pain management after complex spine surgery

  2021cites this paper
• Low back pain in disorders of the intervertebral disc – bio-psycho-social conditions

  2021cites this paper
• Atualização em farmacologia da dor: quais são as opções atuais para o tratamento da dor crônica?

  2021cites this paper
• Pain management strategies in orthopedic extremity trauma

  2021cites this paper
• Potential benefits of gallic acid as skeletal muscle relaxant in animal experimental models

  2021cites this paper
• Multimodal Analgesic Management for Lumbar Decompression Surgery in the Ambulatory Setting: Clinical Case Series and Review of the Literature.

  2021cites this paper
• Low Back Disorders

  2021cites this paper
• Muscle Relaxants for Acute and Chronic Pain.

  2020cites this paper
• Risk of knee replacement after anterior cruciate ligament injury: a systematic review

  2020cites this paper
• In dogs with metaldehyde intoxication, are benzodiazepines more effective than methocarbamol in relaxing muscles and reducing tremors?

  2020influential citation
• Opioid Alternative Medication and Clinical Dilemmas

  2020cites this paper
• PLASTA National Webinar Series: A developing model for remote surgical education

  2020cites this paper
• Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents.

  2020cites this paper
• Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery

  2020cites this paper
• Neck Pain and Lower Back Pain.

  2020cites this paper
• Association of combination opioid, benzodiazepine, and muscle relaxant usage with emergency department visits in a nationwide cohort in the United States

  2020cites this paper
• COVID-19 lockdown and beyond: Home practice solutions for developing microsurgical skills.

  2020cites this paper
• Pain control following alloplastic breast reconstruction with muscle relaxant: A randomized controlled trial.

  2020cites this paper
• Assessment of Physician Prescribing of Muscle Relaxants in the United States, 2005-2016

  2020cites this paper
• A multicentre randomized controlled follow-up study of the effects of the underwater traction therapy in chronic low back pain

  2020cites this paper
• Can Brain Cure Pain and Fear? Effect of Graded Motor Imagery on Post Operative Lumbar Degenerative Diseases -Randomized Control Trial

  2020cites this paper
• Lumbar Radiculopathy

  2020cites this paper
• Antispasmodics and Muscle Relaxants

  2019cites this paper
• A randomized, placebo controlled trial of ibuprofen + metaxalone, tizanidine, or baclofen for acute low back pain

  2019influential citation
• Approach to non-compressive back pain

  2019cites this paper
• Prevalence of patellofemoral joint osteoarthritis after anterior cruciate ligament injury and associated risk factors: A systematic review

  2019cites this paper
• A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain.

  2019cites this paper
• Muscle Relaxants and Antispasticity Drugs

  2019cites this paper
• Lomber facet injections are equally effective for treatment of facet joint-induced low back painin the obese compared to non-obese population : a single center retrospective study

  2019cites this paper
• Multimodal Pain Management and Postoperative Outcomes in Lumbar Spine Fusion Surgery: A Population-Based Cohort Study.

  2019cites this paper
• Anesthesia and postoperative pain control following spine surgery

  2018cites this paper
• Pain management in neurocritical care; an update

  2018cites this paper
• Pain management in neurocritical care

  2018cites this paper
• Adjuvant analgesics for spine surgery.

  2018cites this paper
• Rehabilitacija nakon operacije hernije diska u lumbalnom dijelu kralježnice

  2018cites this paper
• Chapter 67 – Chronic Low Back Pain

  2018cites this paper
• Radiofrequency and Methylprednisolone in Treatment of Lower Back Pain Caused by Facet Joint Syndrome: Comparison of the Outcomes

  2018cites this paper
• 33 – Low Back Pain

  2018cites this paper
• Correction to: The effects of the calcium-magnesium-bicarbonate content in thermal mineral water on chronic low back pain: a randomized, controlled follow-up study

  2018cites this paper
• The use of skeletal muscle relaxants in musculoskeletal injuries: what is the evidence?

  2018cites this paper
• Effects of supplemental heat therapy in multimodal treated chronic low back pain patients on strength and flexibility

  2018cites this paper
• In vivo nonspecific immunomodulatory and antispasmodic effects of common purslane (Portulaca oleracea Linn.) leaf extracts in ICR mice.

  2018cites this paper
• The effects of the calcium-magnesium-bicarbonate content in thermal mineral water on chronic low back pain: a randomized, controlled follow-up study

  2018cites this paper
• Spinal manipulation and therapeutic exercises in treating post-surgical resurgent lumbar radiculopathy

  2017cites this paper
• Review of Recent Advances in Pain Management for Pediatric Spinal Fusion

  2017cites this paper
• Musculoskeletal Low Back Pain in School-aged Children: A Review

  2017cites this paper
• The Impact of Spinal Manipulation Therapy (SMT) for Nonspecific Low Back Pain in the Military Population: An Integrative Review with Presentation of the SMT Toolkit to Primary Care Providers

  2017cites this paper
• Lumbar Spine Procedures for the Treatment of Pain in the Rehabilitation Patient

  2017cites this paper
• Incidence of Knee Osteoarthritis after Anterior Cruciate Ligament Injury- A Systematic Review

  2017cites this paper
• NaproxenWithCyclobenzaprine,Oxycodone/Acetaminophen, or Placebo for TreatingAcute LowBackPain A Randomized Clinical Trial

  2017cites this paper
• METHOD DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF TOLPERISONE HCl AND ETODOLAC IN BULK AND ITS PHARMACEUTICAL DOSAGE FORMULATIONS

  2017cites this paper
• Complementary therapies in addition to medication for patients with nonchronic, nonradicular low back pain: a systematic review☆

  2017cites this paper
• Diazepam Is No Better Than Placebo When Added to Naproxen for Acute Low Back Pain

  2017cites this paper
• Skeletal Muscle Relaxants #340

  2017cites this paper
• Efficacy and tolerability of muscle relaxants for low back pain: Systematic review and meta‐analysis

  2017cites this paper
• Potentially inappropriate medications in geriatric population: A clinical update for oral medicine and orofacial pain practitioners

  2017cites this paper
• PURLs: More isn't better with acute low back pain treatment.

  2016cites this paper
• Pharmacological and Interventional Management of Pain After Whiplash Injury.

  2016cites this paper
• A Narrative Review of Lumbar Fusion Surgery With Relevance to Chiropractic Practice.

  2016cites this paper
• Acute Pain Management in the Emergency Department

  2016cites this paper
• HIV and chronic pain: musculoskeletal pain

  2016cites this paper
• Adjuvant Agents in Chronic Pain Therapy

  2016cites this paper
• Treating more than just the back: the role of individualised multidimensional care for chronic low back pain

  2016cites this paper
• Lumbar herniated disc: spontaneous regression

  2016cites this paper
• Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain: A Systematic Review and Meta-analysis.

  2016cites this paper
• Medications Used for the Treatment of Back Pain

  2016cites this paper
• Efficacy , Tolerability , and Dose-Dependent Effects of Opioid Analgesics for LowBack Pain

  2016cites this paper
• The effect of chlorzoxazone on acute pain after spine surgery. A randomized, blinded trial

  2016influential citation
• Management of neck pain and associated disorders: A clinical practice guideline from the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration

  2016cites this paper
• Evaluation of efficacy and tolerability of eperisone and thiocolchicoside in treatment of low back pain associated with muscle spasm: An open label, prospective, randomized controlled trial -

  2016cites this paper
• Nonoperative management of cervical disc herniations: An evidence-based approach

  2016cites this paper
• Lumbar Degenerative Disk Disease: Workup and Conservative Treatment

  2016cites this paper
• Pharmacotherapy in low back pain

  2016cites this paper