Correlation of p53 and the proto-oncogene eIF4E in larynx cancers: prognostic implications.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Cancer Research

• Publication date

  2000-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10910074
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ear nose throat

  1999cited by this paper
• Detection of the proto-oncogene eIF4E in larynx and hypopharynx cancers.

  1999cited by this paper
• Expression of eIF4E During Head and Neck Tumorigenesis: Possible Role in Angiogenesis

  1999cited by this paper
• eIF4E expression in tumors: its possible role in progression of malignancies.

  1999cited by this paper
• Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

  1999cited by this paper
• Analysis of surgical margins with the molecular marker eIF4E: a prognostic factor in patients with head and neck cancer.

  1999influential reference
• Local and distant recurrence after conservative management of "very low-risk" breast cancer are dependent events: a 10-year follow-up.

  1998cited by this paper
• Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer

  1997cited by this paper
• Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma

  1997cited by this paper
• Oncogenic transcription factors in the human acute leukemias.

  1997cited by this paper
• Detection of p53 protein in oropharyngeal carcinoma. Prognostic implications.

  1996cited by this paper
• p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma.

  1996cited by this paper
• p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.

  1996cited by this paper
• mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

  1996cited by this paper
• p53 Expression: Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma

  1996cited by this paper
• Overexpression of p53 Predicts Organ Preservation Using Induction Chemotherapy and Radiation in Patients with Advanced Laryngeal Cancer

  1995cited by this paper
• Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.

  1995influential reference
• The proto‐oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas

  1995cited by this paper
• Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

  1994cited by this paper
• The effect of loco-regional control on distant metastatic dissemination in carcinoma of the nasopharynx: an analysis of 1301 patients.

  1994cited by this paper
• Correlation between p53 gene expression and tumor‐cell proliferation in oropharyngeal cancer

  1994cited by this paper
• Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.

  1994cited by this paper
• p53 In tumour pathology: Can we trust immunohistochemistry?—revisited!

  1994cited by this paper
• Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

  1994cited by this paper
• p53 is required for radiation-induced apoptosis in mouse thymocytes

  1993cited by this paper
• The incidence of p53 mutations increases with progression of head and neck cancer.

  1993cited by this paper
• p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer.

  1993cited by this paper
• High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx.

  1992cited by this paper
• p53 overexpression correlates with increased survival in patients with squamous carcinoma of the tongue base.

  1992cited by this paper
• Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.

  1992cited by this paper
• Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53.

  1992cited by this paper
• Frequent p53 mutations in head and neck cancer.

  1992cited by this paper
• p53 over‐expression is an early event in the development of human squamous‐cell carcinoma of the larynx: Genetic and prognostic implications

  1992cited by this paper
• Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck.

  1991cited by this paper
• Participation of p53 protein in the cellular response to DNA damage.

  1991cited by this paper
• A genetic model for colorectal tumorigenesis.

  1990cited by this paper
• Prognostic factors for loco/regional control and metastasis and the impact on survival.

  1986cited by this paper
• The clonal evolution of tumor cell populations.

  1976cited by this paper

• P53 Expression Associated With Smoking for Laryngeal Tumor Recurrence in Patients With Free Surgical Margins

  2025cites this paper
• The impact of histology and molecular biology in refining the prognostic value of surgical margins in head and neck oncology – A narrative review

  2025cites this paper
• Trends and Future Directions in Margin Analysis for Head and Neck Cancers.

  2024cites this paper
• P53 regulates CCAAT/Enhancer Binding Protein β gene expression.

  2023cites this paper
• The prognostic role of immunohistochemical markers in surgical margins of Indian patients with oral squamous cell carcinoma- a retrospective study protocol

  2021cites this paper
• Role of Immunohistochemical Markers in Surgical Margins of Patients with Head and Neck Carcinoma – A Systematic Review

  2020cites this paper
• Molecular margins in head and neck cancer: Current techniques and future directions.

  2020cites this paper
• p53 Immunoexpression as a Prognostic Indicator of Survival in Head and Neck Squamous Cell Carcinoma

  2020cites this paper
• The eukaryotic initiation factor 4E (eIF4E) as a predictive biomarker in the negative margins of resected head and neck and oral cancers: Is there a role for tailoring adjuvant radiotherapy

  2019cites this paper
• “Clinicopathological and Prognostic Significance of Her-2/Neu Immunoexpression in Head and Neck Squamous Cell Carcinomas and its Association with Survival in Indian Population”

  2019cites this paper
• Biological tailoring of adjuvant radiotherapy in head and neck and oral malignancies – The potential role of p53 and eIF4E as predictive parameters

  2019cites this paper
• Translation Control by p53

  2018cites this paper
• Predictability of Recurrence using Immunohistochemistry to delineate Surgical Margins in mucosal Head and Neck Squamous Cell Carcinoma (PRISM-HNSCC): study protocol for a prospective, observational and bilateral study in Australia and India

  2017cites this paper
• Immunohistochemical expression levels of p53 and eIF4E markers in histologically negative surgical margins, and their association with the clinical outcome of patients with head and neck squamous cell carcinoma.

  2016influential citation
• Updated overview of current biomarkers in head and neck carcinoma.

  2016cites this paper
• MicroRNA‐34c‐5p is related to recurrence in laryngeal squamous cell carcinoma

  2015cites this paper
• Contemporary Assessment and Management of Head and Neck Cancer Surgical Margins

  2015cites this paper
• Superparamagnetic iron oxide nanoparticles: Promising tools in cancer nanotheranostics

  2015cites this paper
• LAMP 3 and TP 53 overexpression predicts poor outcome in laryngeal squamous cell carcinoma

  2015cites this paper
• LAMP3 and TP53 overexpression predicts poor outcome in laryngeal squamous cell carcinoma.

  2015cites this paper
• HPV18 E7 induces the over-transcription of eIF4E gene in cervical cancer

  2015cites this paper
• p53, a translational regulator: contribution to its tumour-suppressor activity

  2015cites this paper
• Molecular Biomarkers of Laryngeal Cancer Laryngeal squamous cell carcinoma (LSCC) Tumor markers

  2015cites this paper
• The prognostic value of p53 expression in negative surgical margins of early glottic carcinoma in the prediction of local recurrences

  2014cites this paper
• Over-expression of p53, p21 and Cdc2 in histologically negative surgical margins is correlated with local recurrence of laryngeal squamous cell carcinoma.

  2014cites this paper
• Expression of eukaryotic initiation factor 4 E in hypopharyngeal carcinoma

  2014cites this paper
• Molecular diagnosis of minimal residual head and neck cancer and field cancerization

  2014cites this paper
• An Australian retrospective study to evaluate the prognostic role of p53 and eIF4E cancer markers in patients with head and neck squamous cell carcinoma (HNSCC): study protocol.

  2013influential citation
• Molecular biomarkers of prognosis in laryngeal squamous cell carcinoma

  2013cites this paper
• HPV E6 induces eIF4E transcription to promote the proliferation and migration of cervical cancer

  2013cites this paper
• Eukaryotic Translation Elongation Factor 1-Alpha 1 Inhibits p53 and p73 Dependent Apoptosis and Chemotherapy Sensitivity

  2013cites this paper
• Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype

  2012cites this paper
• Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma

  2012cites this paper
• EIF 4 E ( eukaryotic translation initiation factor 4 E )

  2012influential citation
• Head and neck inflammatory myofibroblastic tumor (IMT): evaluation of clinicopathologic and prognostic features.

  2012cites this paper
• Targeting Translation Dependence in Cancer

  2011cites this paper
• Head and Neck Cancers

  2011cites this paper
• Loss of heterozygosity at 9p and p53 immunopositivity in surgical margins predict local relapse in head and neck squamous cell carcinoma

  2011cites this paper
• Analytical And Quantitativecytology And Histology

  2010cites this paper
• Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue.

  2010cites this paper
• Optical and molecular techniques to identify tumor margins within the larynx

  2010cites this paper
• Head and Neck Tumours

  2010cites this paper
• Overexpression of eukaryotic initiation factor 4E (eIF4E) and its clinical significance in lung adenocarcinoma.

  2009cites this paper
• The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth

  2009cites this paper
• Benigne und potentiell maligne Läsionen des Plattenepithels und Plattenepithelkarzinom

  2009cites this paper
• Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue

  2009cites this paper
• Translation initiation: a critical signalling node in cancer

  2009cites this paper
• Correlation of p53, MDM2 and p14ARF protein expression in human esophageal squamous cell carcinoma

  2009cites this paper
• Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer

  2009cites this paper
• A Prospective Trial on Initiation Factor 4E (eIF4E) Overexpression and Cancer Recurrence in Node-Negative Breast Cancer

  2008cites this paper
• Gene Expression Profiling Identifies Genes Predictive of Oral Squamous Cell Carcinoma

  2008influential citation
• Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.

  2008cites this paper
• [Genes associated with tobacco smoke-associated cancer of head and neck].

  2008cites this paper
• Squamous Cell Carcinomas Like 2 as a New Poor Prognosis Marker of − Lysyl Oxidase

  2008cites this paper
• Significance of eIF4E expression in skin squamous cell carcinoma

  2007cites this paper
• The uncertainty of the surgical margin in the treatment of head and neck cancer.

  2007cites this paper
• Translational control: a target for cancer therapy.

  2007cites this paper
• Molecular biology of squamous cell carcinoma of the head and neck

  2006cites this paper
• Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer.

  2006cites this paper
• Cyclin D1 Expression in Laryngeal Cancer.

  2006cites this paper
• Benign and Potentially Malignant Lesions of the Squamous Epithelium and Squamous Cell Carcinoma

  2006cites this paper
• Profiling early head and neck cancer

  2005cites this paper
• Clinical and molecular prognostic factors in operable laryngeal cancer

  2005cites this paper
• Molecular markers in laryngeal squamous cell carcinoma: towards an integrated clinicobiological approach.

  2005cites this paper
• A Simplified Method for Purifying Osteoclasts from Human Giant Cell Tumor of Bone

  2005cites this paper
• Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53.

  2005cites this paper
• A Prospective Trial on Initiation Factor 4E (eIF4E) Overexpression and Cancer Recurrence in Node-Positive Breast Cancer

  2005cites this paper
• Regulation of Translation and Cancer

  2004cites this paper
• Translational control and metastatic progression: Enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

  2004cites this paper
• Postgenomic global analysis of translational control induced by oncogenic signaling

  2004cites this paper
• Cytokeratin-17 as a Potential Marker for Squamous Cell Carcinoma of the Larynx

  2004cites this paper
• Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents.

  2004cites this paper
• TP53 and head and neck neoplasms

  2003cites this paper
• Proteomic analysis of eIF‐5A in lung adenocarcinomas

  2003cites this paper
• Multivariate Analysis of Prognostic Factors in 1 252 Consecutive Patients Treated with Primary Radiotherapy

  2003cites this paper
• Prognostic significance of chosen tumour indicators (angiogenesis, cell proliferation and apoptosis) in laryngeal cancer

  2003cites this paper
• Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis

  2003cites this paper
• Treatment failure and margin status in head and neck cancer. A critical view on the potential value of molecular pathology.

  2002cites this paper
• Prognosefaktoren bei Kopf-Hals-Karzinomen

  2002cites this paper
• Gradual deregulation and loss of PCPH expression in the progression of human laryngeal neoplasia

  2002cites this paper
• The Emerging Role for the mRNA Cap-Binding Protein, EIF-4E, in Metastatic Progression

  2002cites this paper
• Molecular genetics of head and neck cancer.

  2002cites this paper
• The molecular biology of laryngeal cancer.

  2002cites this paper
• Expression of eukaryotic initiation factor 4E in atypical adenomatous hyperplasia and adenocarcinoma of the human peripheral lung.

  2002cites this paper
• Molecular Analysis of Surgical Margins in Head and Neck Squamous Cell Carcinoma Patients

  2002influential citation
• Tumor markers in squamous cell carcinoma of the head and neck: clinical effectiveness and prognostic value

  2001cites this paper
• COX‐2 expression in dysplasia of the head and neck

  2001cites this paper
• Expression of the translation initiation factor eIF4E in the polyp-cancer sequence in the colon.

  2001cites this paper
• COX-2 expression in dysplasia of the head and neck: correlation with elF4E.

  2001cites this paper
• Iranian Journal of Basic Medical Sciences Hpv18 E7 Induces the Over-transcription of Eif4e Gene in Cervical Blockincancer

  year unknowncites this paper