Interstitial cells of Cajal, macrophages and mast cells in the gut musculature: morphology, distribution, spatial and possible functional interactions

H. Mikkelsen

Published 2010 in Journal of Cellular and Molecular Medicine

ABSTRACT

•  Introduction •  Identification of the cells ‐  ICC ‐  Macrophages ‐  Activation ‐  Identification ‐  Mast cells ‐  Activation ‐  Identification •  Cell distribution ‐  ICC in rodent gastrointestinal tract ‐  ICC in human gastrointestinal tract ‐  Macrophages in rodent gastrointestinal tract ‐  Macrophages in human gastrointestinal tract ‐  Mast cells in rodent gastrointestinal tract ‐  Mast cells in human gastrointestinal tract •  Inflammation ‐  Models of inflammation ‐  LPS administration ‐  Surgical anastomosis ‐  Ileal obstruction ‐  Post‐operative ileus ‐  Helminth infections ‐  Inflammatory bowel disease ‐  Achalasia •  Diabetes mellitus ‐  NOD/LtJ mice ‐  STZ‐DM rats •  Conclusions

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