Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Neuron

• Publication date

  2001-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0896-6273(01)00236-7PMID 11301020
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cyclic nucleotide-gated ion channels.

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  2001cited by this paper
• A robust, detergent-friendly method for mass spectrometric analysis of integral membrane proteins.

  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
• Domains Responsible for Constitutive and Ca2+-Dependent Interactions between Calmodulin and Small Conductance Ca2+-Activated Potassium Channels

  1999influential reference
• Structural rearrangements underlying K+-channel activation gating.

  1999cited by this paper
• The moving parts of voltage-gated ion channels

  1998cited by this paper
• Mechanism of calcium gating in small-conductance calcium-activated potassium channels

  1998cited by this paper
• Evolutionary link between prokaryotic and eukaryotic K+ channels.

  1998cited by this paper
• Crystallography & NMR system: A new software suite for macromolecular structure determination.

  1998cited by this paper
• Large-scale protein structure modeling of the Saccharomyces cerevisiae genome.

  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
• Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

  1997cited by this paper
• Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method.

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997influential reference
• Handbook of Biological Physics

  1996cited by this paper
• Chapter 21 K+ circulation across the prokaryotic cell membrane: K+-uptake systems

  1996influential reference
• The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins

  1996cited by this paper
• Hypothesis for a serine proteinase-like domain at the COOH terminus of Slowpoke calcium-activated potassium channels

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• Structure and function of cyclic nucleotide-gated channels.

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• A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium.

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• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• An Escherichia coli homologue of eukaryotic potassium channel proteins.

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• The CCP4 suite: programs for protein crystallography.

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• AMoRe: an automated package for molecular replacement

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• Introduction to protein structure

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• Improved methods for building protein models in electron density maps and the location of errors in these models.

  1991cited by this paper
• Phase annealing in SHELX-90: direct methods for larger structures

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• Periplasmic binding protein structure and function. Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine.

  1989influential reference
• Ionic channels of excitable membranes

  1984cited by this paper

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