Role of T-type channels in vasomotor function: team player or chameleon?

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Pflügers Archiv: European Journal of Physiology

• Publication date

  2014-01-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00424-013-1430-xPMID 24482062
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Low threshold T‐type calcium channels as targets for novel epilepsy treatments

  2014cited by this paper
• Nitric oxide suppresses vascular voltage-gated T-type Ca2+ channels through cGMP/PKG signaling.

  2014cited by this paper
• Myogenic tone is impaired at low arterial pressure in mice deficient in the low‐voltage‐activated CaV3.1 T‐type Ca2+ channel

  2013cited by this paper
• Surface expression and function of Cav3.2 T-type calcium channels are controlled by asparagine-linked glycosylation

  2013cited by this paper
• Functional and pharmacological consequences of the distribution of voltage‐gated calcium channels inthe renal blood vessels

  2013cited by this paper
• Spreading vasodilatation in the murine microcirculation: attenuation by oxidative stress‐induced change in electromechanical coupling

  2013cited by this paper
• Voltage-activated Ca(2+) channels in rat renal afferent and efferent myocytes: no evidence for the T-type Ca(2+) current.

  2013cited by this paper
• Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

  2013cited by this paper
• T-type calcium channels: functional regulation and implication in pain signaling.

  2013cited by this paper
• Modulation of low-voltage-activated T-type Ca²⁺ channels.

  2013cited by this paper
• Identification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone development.

  2013cited by this paper
• T-type calcium channels in burst-firing, network synchrony, and epilepsy.

  2013cited by this paper
• Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle

  2013cited by this paper
• How do T-type calcium channels control low-threshold exocytosis?

  2012cited by this paper
• p47phox Is Required for Afferent Arteriolar Contractile Responses to Angiotensin II and Perfusion Pressure in Mice

  2012cited by this paper
• Insulin-mediated upregulation of T-type Ca2+ currents in GH3 cells is mediated by increased endosomal recycling and incorporation of surface membrane Cav3.1 channels.

  2012cited by this paper
• Hydrogen peroxide mediates oxidant‐dependent stimulation of arterial smooth muscle L‐type calcium channels

  2012cited by this paper
• Cav3 T‐type calcium channels

  2012cited by this paper
• Sympathetic overdrive in obesity involves purinergic hyperactivity in the resistance vasculature

  2011cited by this paper
• T‐type calcium channels and vascular function: the new kid on the block?

  2011cited by this paper
• Free radical signalling underlies inhibition of CaV3.2 T‐type calcium channels by nitrous oxide in the pain pathway

  2011cited by this paper
• T-type voltage-gated calcium channels regulate the tone of mouse efferent arterioles.

  2011cited by this paper
• Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

  2011cited by this paper
• Choreographing the adenylyl cyclase signalosome: sorting out the partners and the steps

  2011cited by this paper
• T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

  2011cited by this paper
• Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat

  2010cited by this paper
• G Protein-Mediated Inhibition of Cav3.2 T-Type Channels Revisited

  2010cited by this paper
• Caveolin-3 Regulates Protein Kinase A Modulation of the CaV3.2 (α1H) T-type Ca2+ Channels*

  2010cited by this paper
• Dihydropyridine-Insensitive Calcium Currents Contribute to Function of Small Cerebral Arteries

  2010cited by this paper
• NADPH Oxidase-Dependent Regulation of T-Type Ca2+ Channels and Ryanodine Receptors Mediate the Augmented Exocytosis of Catecholamines from Intermittent Hypoxia-Treated Neonatal Rat Chromaffin Cells

  2010cited by this paper
• The CaV3.2 T-Type Ca2+ Channel Is Required for Pressure Overload–Induced Cardiac Hypertrophy in Mice

  2009cited by this paper
• NON‐L‐TYPE VOLTAGE‐DEPENDENT CALCIUM CHANNELS CONTROL VASCULAR TONE OF THE RAT BASILAR ARTERY

  2009cited by this paper
• Heterogeneity of L- and T-Channels in the Vasculature: Rationale for the Efficacy of Combined L- and T-Blockade

  2009cited by this paper
• Ca2+ signaling by T-type Ca2+ channels in neurons

  2009cited by this paper
• Regulation of T-type calcium channels: signalling pathways and functional implications.

  2009cited by this paper
• T-type calcium channels are regulated by hypoxia/reoxygenation in ventricular myocytes.

  2009cited by this paper
• Regulation of neuronal T-type calcium channels.

  2009cited by this paper
• Alternative splicing within the I–II loop controls surface expression of T‐type Cav3.1 calcium channels

  2008cited by this paper
• T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites

  2008cited by this paper
• PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors.

  2007cited by this paper
• Connexin40 Is Essential for the Pressure Control of Renin Synthesis and Secretion

  2007cited by this paper
• Regulation of T-type calcium channels by Rho-associated kinase

  2007cited by this paper
• Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.

  2007cited by this paper
• Connexin40 regulates renin production and blood pressure.

  2007cited by this paper
• Voltage‐dependent calcium channels of dog basilar artery

  2007cited by this paper
• The I–II Loop Controls Plasma Membrane Expression and Gating of Cav3.2 T-Type Ca2+ Channels: A Paradigm for Childhood Absence Epilepsy Mutations

  2007cited by this paper
• Ca2+ channel subtypes and pharmacology in the kidney.

  2007cited by this paper
• T-type calcium channels: the never ending story.

  2006cited by this paper
• Caveolins in vascular smooth muscle: form organizing function.

  2006cited by this paper
• Bradycardia and Slowing of the Atrioventricular Conduction in Mice Lacking CaV3.1/&agr;1G T-Type Calcium Channels

  2006cited by this paper
• Profiling the array of Cav3.1 variants from the human T‐type calcium channel gene CACNA1G: Alternative structures, developmental expression, and biophysical variations

  2006cited by this paper
• A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies.

  2006cited by this paper
• Antihypertensive Effects of the Putative T-Type Calcium Channel Antagonist Mibefradil Are Mediated by the L-Type Calcium Channel Cav1.2

  2005cited by this paper
• Pathophysiological significance of T-type Ca2+ channels: role of T-type Ca2+ channels in renal microcirculation.

  2005cited by this paper
• Myogenic contraction in rat skeletal muscle arterioles: smooth muscle membrane potential and Ca(2+) signaling.

  2005cited by this paper
• Expression of T‐type calcium channel splice variants in human glioma

  2004cited by this paper
• Plasma Membrane Expression of T-type Calcium Channel α1 Subunits Is Modulated by High Voltage-activated Auxiliary Subunits*

  2004cited by this paper
• The impact of splice isoforms on voltage‐gated calcium channel α1 subunits

  2004cited by this paper
• Calcium channel currents in isolated smooth muscle cells from the basilar artery of the guinea pig

  2004cited by this paper
• Differential Calcium Regulation by Hydrogen Peroxide and Superoxide in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats

  2004cited by this paper
• Depolarization‐induced calcium influx in rat mesenteric small arterioles is mediated exclusively via mibefradil‐sensitive calcium channels

  2004cited by this paper
• Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels.

  2003cited by this paper
• Dominant role of smooth muscle L‐type calcium channel Cav1.2 for blood pressure regulation

  2003cited by this paper
• Abnormal Coronary Function in Mice Deficient in α1H T-type Ca2+ Channels

  2003cited by this paper
• Relative contributions of NO and gap junctional communication to endothelium-dependent relaxations of rabbit resistance arteries vary with vessel size.

  2002cited by this paper
• Functional diversity in neuronal voltage-gated calcium channels by alternative splicing of Cavα1

  2002cited by this paper
• Multiple regulation by external ATP of nifedipine‐insensitive, high voltage‐activated Ca2+ current in guinea‐pig mesenteric terminal arteriole

  2002cited by this paper
• T‐channel‐like pharmacological properties of highvoltage‐activated, nifedipine‐insensitive Ca2+ currents inthe rat terminal mesenteric artery

  2002cited by this paper
• Differential activation of ion channels by inositol 1,4,5‐trisphosphate (IP3)‐ and ryanodine‐sensitive calcium stores in rat basilar artery vasomotion

  2002cited by this paper
• Identification of the T-Type Calcium Channel (CaV3.1d) in Developing Mouse Heart

  2001cited by this paper
• Conducted vasoconstriction in rat mesenteric arterioles: role for dihydropyridine-insensitive Ca(2+) channels.

  2001cited by this paper
• Alternatively spliced alpha(1G) (Ca(V)3.1) intracellular loops promote specific T-type Ca(2+) channel gating properties.

  2001cited by this paper
• Differential Expression of T- and L-Type Voltage-Dependent Calcium Channels in Renal Resistance Vessels

  2001cited by this paper
• Alternatively Spliced α1G (CaV3.1) Intracellular Loops Promote Specific T-Type Ca2+ Channel Gating Properties

  2001cited by this paper
• Neuronal distribution and functional characterization of the calcium channel α2δ‐2 subunit

  2000cited by this paper
• Molecular and Functional Properties of the Human α1G Subunit That Forms T-type Calcium Channels*

  2000cited by this paper
• Molecular and functional properties of the human alpha(1G) subunit that forms T-type calcium channels.

  2000cited by this paper
• Molecular cloning and functional expression of Cav3.1c, a T‐type calcium channel from human brain

  2000cited by this paper
• Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit.

  2000cited by this paper
• Predominant distribution of nifedipine-insensitive, high voltage-activated Ca2+ channels in the terminal mesenteric artery of guinea pig.

  1999cited by this paper
• Structure and alternative splicing of the gene encoding α1G, a human brain T calcium channel α1 subunit

  1999cited by this paper
• The myogenic response: established facts and attractive hypotheses.

  1999cited by this paper
• Structure and alternative splicing of the gene encoding alpha1G, a human brain T calcium channel alpha1 subunit.

  1999cited by this paper
• The effect of α2‐δ and other accessory subunits on expression and properties of the calcium channel α1G

  1999cited by this paper
• GABA is the principal fast-acting excitatory transmitter in the neonatal brain.

  1999cited by this paper
• Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H.

  1999cited by this paper
• The effect of alpha2-delta and other accessory subunits on expression and properties of the calcium channel alpha1G.

  1999cited by this paper
• The effect of overexpression of auxiliary Ca2+ channel subunits on native Ca2+ channel currents in undifferentiated mammalian NG108–15 cells

  1998cited by this paper
• Ca2+ channels, ryanodine receptors and Ca(2+)-activated K+ channels: a functional unit for regulating arterial tone.

  1998cited by this paper
• ATP‐sensitive K+ channel activation by calcitonin gene‐related peptide and protein kinase A in pig coronary arterial smooth muscle

  1998cited by this paper
• Voltage-gated calcium channel currents in human coronary myocytes. Regulation by cyclic GMP and nitric oxide.

  1997cited by this paper
• Prevention of high blood pressure by reducing sympathetic innervation in the spontaneously hypertensive rat.

  1996cited by this paper
• Modulation of Ca2+ channel activity by ATP metabolism and internal Mg2+ in guinea‐pig basilar artery smooth muscle cells.

  1996cited by this paper
• Sodium nitroprusside and cGMP decrease Ca2+ channel availability in basilar artery smooth muscle cells

  1996cited by this paper
• gamma-Aminobutyric acid (GABA): a fast excitatory transmitter which may regulate the development of hippocampal neurones in early postnatal life.

  1994cited by this paper
• γ-Aminobutyric acid (GABA): a fast excitatory transmitter which may regulate the development of hippocampal neurones in early postnatal life

  1994cited by this paper
• Calcium current in smooth muscle cells from normotensive and genetically hypertensive rats.

  1994cited by this paper
• Single calcium channels in resistance-sized cerebral arteries from rats.

  1993cited by this paper
• Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.

  1993cited by this paper
• Calcium currents elicited by voltage steps and steady voltages in myocytes isolated from the rat basilar artery.

  1993cited by this paper

• Functional Role of Piezo1 Channels in Smooth Muscle Cells of Rat Cerebral Arteries under Normal Conditions and Chronic Carotid Artery Stenosis

  2026cites this paper
• Updates on Intrinsic Medicinal Chemistry of 1,4-dihydropyridines, Perspectives on Synthesis and Pharmacokinetics of Novel 1,4-dihydropyrimidines as Calcium Channel Blockers: Clinical Pharmacology.

  2025cites this paper
• Pacemaker activity and ion channels in the sinoatrial node cells: MicroRNAs and arrhythmia.

  2022cites this paper
• Potential Benefits of Flavonoids on the Progression of Atherosclerosis by Their Effect on Vascular Smooth Muscle Excitability

  2021cites this paper
• Pharmacology of Calcium Channel

  2020cites this paper
• Basic Principles of Cardiac Electrophysiology

  2020cites this paper
• Gaseous Signaling Molecules in Cardiovascular Function: From Mechanisms to Clinical Translation.

  2018cites this paper
• Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels

  2018cites this paper
• T‐type voltage gated calcium channels are involved in endothelium‐dependent relaxation of mice pulmonary artery

  2017cites this paper
• Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

  2017cites this paper
• Relevance of tissue specific subunit expression in channelopathies.

  2017cites this paper
• Calmodulin regulates Cav3 T-type channels at their gating brake

  2017cites this paper
• Voltage-dependent inward currents in smooth muscle cells of skeletal muscle arterioles

  2017cites this paper
• [New calcium channel blockers for the treatment of hypertension].

  2017cites this paper
• Intracellular Ca 2+ Regulation

  2017cites this paper
• Regulation of the T‐type Ca2+ channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2S in nociception

  2016cites this paper
• Investigational calcium channel blockers for the treatment of hypertension

  2016influential citation
• Pain management in patients with vascular disease.

  2016cites this paper
• Mechanisms Underlying Enhanced Noradrenaline-Induced Femoral Arterial Contractions of Spontaneously Hypertensive Rats: Involvement of Endothelium-Derived Factors and Cyclooxygenase-Derived Prostanoids.

  2016cites this paper
• Age‐dependent impact of CaV3.2 T‐type calcium channel deletion on myogenic tone and flow‐mediated vasodilatation in small arteries

  2016cites this paper
• Cardiac ion channels

  2015cites this paper
• New Role of P/Q-type Voltage-gated Calcium Channels: From Transmitter Release to Contraction of Renal Vasculature

  2015cites this paper
• CaV3.1 T-Type Ca2+ Channels Contribute to Myogenic Signaling in Rat Retinal Arterioles.

  2015cites this paper
• Functional importance of T-type voltage-gated calcium channels in the cardiovascular and renal system: news from the world of knockout mice.

  2015cites this paper
• CaV3.2 Channels and the Induction of Negative Feedback in Cerebral Arteries

  2014cites this paper
• Isolated human uterine telocytes: immunocytochemistry and electrophysiology of T-type calcium channels

  2014cites this paper
• Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit

  2014cites this paper
• T-type calcium channels are involved in hypoxic pulmonary hypertension.

  2014cites this paper