Proteomics, transcriptomics and lipidomics of exosomes and ectosomes

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Proteomics

• Publication date

  2013-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/pmic.201200329PMID 23401200
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Leukemia cell to endothelial cell communication via exosomal miRNAs

  2013cited by this paper
• Exosomal miRNAs: Biological Properties and Therapeutic Potential

  2012cited by this paper
• Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers.

  2012cited by this paper
• Breast Cancer Exosome-like Microvesicles and Salivary Gland Cells Interplay Alters Salivary Gland Cell-Derived Exosome-like Microvesicles In Vitro

  2012influential reference
• The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.

  2012cited by this paper
• Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)

  2012cited by this paper
• Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

  2012cited by this paper
• Exosome mimetics: a novel class of drug delivery systems

  2012cited by this paper
• Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

  2012cited by this paper
• Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.

  2012cited by this paper
• Intercellular communication: diverse structures for exchange of genetic information

  2012cited by this paper
• Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

  2012influential reference
• Microparticles: major transport vehicles for distinct microRNAs in circulation

  2012influential reference
• Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis

  2012cited by this paper
• Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry.

  2012cited by this paper
• Bovine milk exosome proteome.

  2012cited by this paper
• Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

  2012influential reference
• Therapeutic Effects of Autologous Tumor-Derived Nanovesicles on Melanoma Growth and Metastasis

  2012cited by this paper
• Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells

  2012influential reference
• Proteomic analysis of microvesicles derived from human mesenchymal stem cells.

  2012cited by this paper
• Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells

  2012cited by this paper
• Proteomics of microparticles after experimental pulmonary embolism.

  2012cited by this paper
• Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

  2012cited by this paper
• A hyphenated microLC‐Q‐TOF‐MS platform for exosomal lipidomics investigations: Application to RCC urinary exosomes

  2012cited by this paper
• RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

  2012influential reference
• Intracellular and extracellular microRNAs in breast cancer.

  2011cited by this paper
• Microvesicles as mediators of intercellular communication in cancer—the emerging science of cellular ‘debris’

  2011cited by this paper
• The Genomic and Proteomic Content of Cancer Cell-Derived Exosomes

  2011cited by this paper
• Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

  2011influential reference
• Proteomic analysis of microvesicles derived from human colorectal cancer ascites

  2011cited by this paper
• Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

  2011cited by this paper
• Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors*

  2011cited by this paper
• Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade: A Critical Role of Interferon-&ggr;

  2011cited by this paper
• Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.

  2011cited by this paper
• The P4-ATPase TAT-5 inhibits the budding of extracellular vesicles in C. elegans embryos.

  2011cited by this paper
• Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy

  2011cited by this paper
• Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells

  2011cited by this paper
• The multifaceted exosome: Biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities

  2011cited by this paper
• Immune-related MicroRNAs are Abundant in Breast Milk Exosomes

  2011influential reference
• Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation*

  2011cited by this paper
• Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice.

  2011cited by this paper
• Intercellular nanovesicle‐mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

  2011cited by this paper
• ExoCarta 2012: database of exosomal proteins, RNA and lipids

  2011cited by this paper
• Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences.

  2011cited by this paper
• Protein profile of exosomes from trabecular meshwork cells.

  2011cited by this paper
• Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

  2011cited by this paper
• Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery

  2011influential reference
• Urinary exosomes and proteomics.

  2011cited by this paper
• Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line

  2010influential reference
• A membranous form of ICAM-1 on exosomes efficiently blocks leukocyte adhesion to activated endothelial cells.

  2010cited by this paper
• Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

  2010cited by this paper
• Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.

  2010cited by this paper
• Tumor and Stem Cell Biology Cancer Research Cell Surface Tetraspanin Tspan 8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

  2010influential reference
• Microparticles: Protagonists of a Novel Communication Network for Intercellular Information Exchange

  2010cited by this paper
• Interventions for preventing infectious complications in haemodialysis patients with central venous catheters.

  2010cited by this paper
• Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle RNA

  2010cited by this paper
• Microvesicles: mediators of extracellular communication during cancer progression

  2010cited by this paper
• Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins[S]

  2010cited by this paper
• Proteomics of microparticles after deep venous thrombosis.

  2010cited by this paper
• Rab27a and Rab27b control different steps of the exosome secretion pathway

  2010cited by this paper
• MHC class II‐associated proteins in B‐cell exosomes and potential functional implications for exosome biogenesis

  2010cited by this paper
• Export of microRNAs and microRNA-protective protein by mammalian cells

  2010influential reference
• Exosomes from human saliva as a source of microRNA biomarkers.

  2010influential reference
• Candidate biomarkers in exosome‐like vesicles purified from rat and mouse urine samples

  2010cited by this paper
• Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription.

  2010cited by this paper
• Characterization of Yeast Extracellular Vesicles: Evidence for the Participation of Different Pathways of Cellular Traffic in Vesicle Biogenesis

  2010cited by this paper
• Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

  2010cited by this paper
• Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells

  2009cited by this paper
• Characterization of vesicles secreted from insulinoma NIT-1 cells.

  2009cited by this paper
• Large-scale proteomics and phosphoproteomics of urinary exosomes.

  2009cited by this paper
• Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats

  2009influential reference
• Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.

  2009cited by this paper
• Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.

  2009cited by this paper
• Proteomic and functional characterisation of platelet microparticle size classes

  2009cited by this paper
• Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

  2009cited by this paper
• Characterization of PKD protein-positive exosome-like vesicles.

  2009cited by this paper
• Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.

  2009cited by this paper
• ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles.

  2009cited by this paper
• Structural heterogeneity and protein composition of exosome‐like vesicles (prostasomes) in human semen

  2009cited by this paper
• Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.

  2009influential reference
• Exosomes: proteomic insights and diagnostic potential

  2009cited by this paper
• Membrane vesicles as conveyors of immune responses

  2009cited by this paper
• Differential stimulation of monocytic cells results in distinct populations of microparticles

  2009cited by this paper
• Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

  2009cited by this paper
• Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.

  2009cited by this paper
• Exosomes--vesicular carriers for intercellular communication.

  2009influential reference
• Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells*

  2009cited by this paper
• Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes

  2009cited by this paper
• Shedding microvesicles: artefacts no more.

  2009influential reference
• Lung cancer secreted microvesicles: Underappreciated modulators of microenvironment in expanding tumors

  2009cited by this paper
• Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

  2009cited by this paper
• Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature*

  2009cited by this paper
• Gram‐positive bacteria produce membrane vesicles: Proteomics‐based characterization of Staphylococcus aureus‐derived membrane vesicles

  2009cited by this paper
• Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

  2009cited by this paper
• Proteomics in gram-negative bacterial outer membrane vesicles.

  2008cited by this paper
• Proteomic profiling of exosomes: Current perspectives

  2008influential reference
• The proteome of red cell membranes and vesicles during storage in blood bank conditions

  2008cited by this paper
• Interactions of Triton X-100 with sphingomyelin and phosphatidylcholine monolayers: influence of the cholesterol content.

  2008cited by this paper
• Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

  2008cited by this paper
• Comparative proteomic analysis of PAI‐1 and TNF‐alpha‐derived endothelial microparticles

  2008cited by this paper

• Hybrid exosomes: a rising horizon for precision cancer therapy

  2026cites this paper
• Isolation of small extracellular vesicles by interacting with inorganic surface

  2026cites this paper
• Extracellular vesicles from alveolar macrophages promotes pulmonary fibrosis through suppression of lung alveolar regeneration

  2026cites this paper
• Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

  2026cites this paper
• Proangiogenic Mechanisms and Modifications of Mesenchymal Stem Cells with a Focus on Neurological Disorders

  2026cites this paper
• A decade of migrasome research: biogenesis, physiological functions, and disease implications

  2025cites this paper
• Current status and future prospects of mesenchymal stem cell-derived exosomes therapy for premature ovarian insufficiency

  2025cites this paper
• Bone Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect Articular Cartilage Through Regulating tRF-Gln-TTG-019/UBL3

  2025cites this paper
• Advances in Dendritic Cell Targeted Delivery System

  2025cites this paper
• Untargeted lipidomics reveals unique lipid signatures of extracellular vesicles from porcine colostrum and milk

  2025cites this paper
• The protein cargo of extracellular vesicles. Recent advances in lung cancer research.

  2025cites this paper
• Extracellular vesicles in Helicobacter pylori-mediated diseases: mechanisms and therapeutic potential

  2025cites this paper
• Mesenchymal stem cell-derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

  2025cites this paper
• Exosomes: a promising microenvironment modulator for spinal cord injury treatment

  2025cites this paper
• Soma-sperm communication during the journey to fertilization: addressing challenges and opportunities†.

  2025cites this paper
• Recent Progress in Developing Extracellular Vesicles as Nanovehicles to Deliver Carbohydrate-Based Therapeutics and Vaccines

  2025cites this paper
• Extracellular Vesicles in the Crosstalk of Autophagy and Apoptosis: A Role for Lipid Rafts

  2025cites this paper
• Effect of Small Extracellular Vesicles Produced by Mesenchymal Stem Cells on 5xFAD Mice Hippocampal Cultures

  2025cites this paper
• Evaluation of Organoid‐Derived Exosomal microRNA as Liquid Biopsy for Colorectal Cancer: A Multicenter Cross‐Sectional Study

  2025cites this paper
• Liquid biopsy in orthopedic trauma: exosomes as functional mediators and mechanistic indicators in post-traumatic complications

  2025cites this paper
• Urinary extracellular vesicle proteins for biomarker discovery in chronic kidney disease

  2025cites this paper
• Mouse Tumor Tissue‐Derived Extracellular Vesicles Induce Angiogenesis Through VEGF Production From Macrophages

  2025cites this paper
• “Attractive” Treatment for Abdominal Aortic Aneurysm Repair: Magnetic Localization of Silk-Iron Packaged Extracellular Vesicles

  2025cites this paper
• Exosome-Based Sensor: A Landmark of the Precision Cancer Diagnostic Era.

  2025cites this paper
• The role of tumor-derived exosomal LncRNA in tumor metastasis

  2025cites this paper
• The dynamics of ubiquitination and its role within the proteome of extracellular vesicles.

  2025cites this paper
• Extracellular Vesicles as Therapeutic Strategy for Ischemic Stroke

  2025cites this paper
• MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

  2025cites this paper
• Stem cells for therapy of neurodegeneration

  2025cites this paper
• Minimum information for studies of extracellular vesicles (MISEV) as toolbox for rigorous, reproducible and homogeneous studies on extracellular vesicles.

  2025cites this paper
• Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations

  2024cites this paper
• Fruit exosomes: a sustainable green cancer therapeutic

  2024cites this paper
• RNA Interference Applied to Crustacean Aquaculture

  2024cites this paper
• Isolation, identification, and challenges of extracellular vesicles: emerging players in clinical applications

  2024cites this paper
• EV71 infection alters the lipid composition of human rhabdomyosarcoma (RD) cells-derived extracellular vesicles

  2024cites this paper
• Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EVISF ) reveals sex-dependent changes in microglial EV proteome in response to Aβ pathology.

  2024cites this paper
• Trends in Developing Extracellular Vesicle-Based Therapeutics

  2024cites this paper
• Therapeutic potential of microglia-derived extracellular vesicles in ischemic stroke.

  2024cites this paper
• Extracellular RNA in oncogenesis, metastasis and drug resistance

  2024cites this paper
• New uses of halofuginone to treat cancer

  2024cites this paper
• Compact bone mesenchymal stem cells-derived paracrine mediators for cell-free therapy in sepsis.

  2024cites this paper
• Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications.

  2024cites this paper
• The Current and Promising Oral Delivery Methods for Protein- and Peptide-Based Drugs

  2024cites this paper
• Axonal Energy Crisis and Calcium Phosphate Dysregulation as Pathogenesis of Optic Disc Drusen

  2024cites this paper
• Engineered and Mimicked Extracellular Nanovesicles for Therapeutic Delivery

  2024cites this paper
• Peptide-based biosensing approaches for targeting breast cancer-derived exosomes.

  2024cites this paper
• Exosomes: A New Hope for Angiogenesis-Mediated Bone Regeneration

  2024cites this paper
• Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per- and polyfluoroalkyl substances.

  2024cites this paper
• Immunomodulation by extracellular vesicle-like nanoparticles from marine macroalgae Sargassum fusiforme: Enhancing Type 1 T helper and cytotoxic T lymphocyte-mediated immune responses

  2024cites this paper
• Recent progress in engineered extracellular vesicles and their biomedical applications.

  2024cites this paper
• Filter-Aided Extracellular Vesicle Enrichment (FAEVEr) for Proteomics

  2024cites this paper
• Exosome nanovesicles: biomarkers and new strategies for treatment of human diseases

  2024cites this paper
• Clinical Impact of Multi-omics profiling of extracellular vesicles in cancer Liquid Biopsy

  2024cites this paper
• Serum Extracellular Vesicles Cargo Approach in Bitches with Mammary Tumors

  2024cites this paper
• Extracellular vesicle proteins as breast cancer biomarkers: Mass spectrometry‐based analysis

  2024cites this paper
• Exosome Cargo in Neurodegenerative Diseases: Leveraging Their Intercellular Communication Capabilities for Biomarker Discovery and Therapeutic Delivery

  2024cites this paper
• Filter-aided extracellular vesicle enrichment (FAEVEr)

  2023cites this paper
• BeWo exomeres are enriched for bioactive extracellular placenta-specific C19MC miRNAs.

  2023cites this paper
• Emerging Microfluidic Tools for Simultaneous Exosomes and Cargo Biosensing in Liquid Biopsy: New Integrated Miniaturized FFF-Assisted Approach for Colon Cancer Diagnosis

  2023cites this paper
• Exosomal Cargo in Ovarian Cancer Dissemination

  2023cites this paper
• Advances and challenges in clinical applications of tumor cell-derived extracellular vesicles.

  2023cites this paper
• The role of exosomes in cancer biology by shedding light on their lipid contents.

  2023cites this paper
• Comparison of Four Purification Methods on Serum Extracellular Vesicle Recovery, Size Distribution, and Proteomics

  2023cites this paper
• Nano-seq analysis reveals different functional tendency between exosomes and microvesicles derived from hUMSC

  2023cites this paper
• Unraveling the Intricate Roles of Exosomes in Cardiovascular Diseases: A Comprehensive Review of Physiological Significance and Pathological Implications

  2023cites this paper
• Mesenchymal stem cell secretome and extracellular vesicles for neurodegenerative diseases: Risk-benefit profile and next steps for the market access

  2023cites this paper
• The morphological and functional ultrastructure of cells in pre-implantation embryos.

  2023cites this paper
• The diagnostic and therapeutic potential of exosomal proteins in breast cancer

  2023cites this paper
• Iron-loaded extracellular vesicles: angel or demon?

  2023cites this paper
• Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EVISF) reveals sex-dependent changes in microglial EV proteome in response to Aβ pathology

  2023cites this paper
• Biomarkers for parkinsonian disorders in CNS-originating EVs: promise and challenges

  2023cites this paper
• Exosome nanovesicles: A potential carrier for therapeutic delivery

  2023cites this paper
• UTX deletion promotes M2 macrophage polarization by epigenetically regulating endothelial cell-macrophage crosstalk after spinal cord injury

  2023cites this paper
• Progress of Endogenous and Exogenous Nanoparticles for Cancer Therapy and Diagnostics

  2023cites this paper
• Quantitative Proteomics for the Identification of Differentially Expressed Proteins in the Extracellular Vesicles of Cervical Cancer Cells

  2023cites this paper
• Exosomal microRNAs and long noncoding RNAs: as novel biomarkers for endometriosis

  2023cites this paper
• Developmental competence of bovine oocytes in maturation media supplemented with follicular fluid exosomes

  2023cites this paper
• Mitochondrial-Derived Vesicles: The Good, the Bad, and the Ugly

  2023cites this paper
• Mitochondria-derived vesicles and their potential roles in kidney stone disease

  2023cites this paper
• Plasma small extracellular vesicles from dogs affected by cutaneous mast cell tumors deliver high levels of miR-21-5p

  2023cites this paper
• Spheresomes are the main extracellular vesicles in low-grade gliomas

  2023cites this paper
• S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos

  2023cites this paper
• Multi-Omics Analysis of Circulating Exosomes in Adherent Long-Term Treated OSA Patients

  2023cites this paper
• Metabolites as extracellular vesicle cargo in health, cancer, pleural effusion, and cardiovascular diseases: An emerging field of study to diagnostic and therapeutic purposes.

  2022cites this paper
• Exosomal miR‐181a‐5p derived from SAOS‐2 cells promotes macrophages M2 polarization by targeting RORA

  2022cites this paper
• UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1

  2022cites this paper
• Tumor-Derived Small Extracellular Vesicles Involved in Breast Cancer Progression and Drug Resistance

  2022cites this paper
• Genetically Engineered Extracellular Vesicles Harboring Transmembrane Scaffolds Exhibit Differences in Their Size, Expression Levels of Specific Surface Markers and Cell-Uptake

  2022cites this paper
• Proteomics of Extracellular Vesicle in Glioblastoma

  2022cites this paper
• Exosomes—Nature’s Lipid Nanoparticles, a Rising Star in Drug Delivery and Diagnostics

  2022cites this paper
• Quantitative proteomics and biological activity of extracellular vesicles engineered to express SARS‐CoV‐2 spike protein

  2022cites this paper
• Ectosomes and exosomes modulate neuronal spontaneous activity.

  2022cites this paper
• Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Applications

  2022influential citation
• Exosomes in Breast Cancer: Involvement in Tumor Dissemination and Prospects for Liquid Biopsy

  2022cites this paper
• Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders.

  2022cites this paper
• EV duty vehicles: Features and functions of ciliary extracellular vesicles

  2022cites this paper
• In Vivo Imaging of Exosomes Labeled with NIR-II Polymer Dots in Liver-Injured Mice.

  2022cites this paper
• Engineered extracellular vesicles: A novel platform for cancer combination therapy and cancer immunotherapy.

  2022cites this paper
• Proteomes of Extracellular Vesicles From Pancreatic Cancer Cells and Cancer-Associated Fibroblasts

  2022cites this paper
• Laminins in tumor-derived exosomes upregulated by ETS1 reprogram omental macrophages to promote omental metastasis of ovarian cancer

  2022cites this paper