Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers

Monoselective γ-C–H olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quaternary carbon centers at the β-position of aliphatic acids.

• Publication year

  2014

• Venue

  Journal of the American Chemical Society

• Publication date

  2014-03-26

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/ja501689jPMID 24666182PMCID 4049142
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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