Localization of calcitonin receptor‐like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat

No abstract is available for this paper.

• Publication year

  2005

• Venue

  The Journal of comparative neurology

• Publication date

  2005-09-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cne.20669PMID 16082677
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat.

  2004cited by this paper
• Biological importance of the peptides of the calcitonin family as revealed by disruption and transfer of corresponding genes.

  2004cited by this paper
• Trypsin IV, a Novel Agonist of Protease-activated Receptors 2 and 4*

  2004cited by this paper
• Intermedin Is a Calcitonin/Calcitonin Gene-related Peptide Family Peptide Acting through the Calcitonin Receptor-like Receptor/Receptor Activity-modifying Protein Receptor Complexes*

  2004cited by this paper
• Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine.

  2004cited by this paper
• Studies on the Effects of the N-Terminal Domain Antibodies of CalcitoninReceptor-Like Receptor and Receptor Activity–Modifying Protein 1 on CalcitoninGene-Related Peptide-Induced Vasorelaxation in Rat Uterine Artery1

  2004cited by this paper
• Vascular actions of calcitonin gene-related peptide and adrenomedullin.

  2004influential reference
• Evidence for the existence of a new receptor for CGRP, which is not CRLR.

  2003cited by this paper
• Expression of calcitonin gene-related peptide receptor components, calcitonin receptor-like receptor and receptor activity modifying protein 1, in the rat placenta during pregnancy and their cellular localization.

  2003cited by this paper
• Novel Receptor Partners and Function of Receptor Activity-modifying Proteins*

  2003cited by this paper
• Three receptor-activity-modifying proteins define calcitonin gene-related peptide or adrenomedullin selectivity of the mouse calcitonin-like receptor in COS-7 cells.

  2003cited by this paper
• Immunohistochemical detection of the calcitonin receptor-like receptor protein in the microvasculature of rat endothelium.

  2003cited by this paper
• Localization and modulation of calcitonin gene-related peptide-receptor component protein-immunoreactive cells in the rat central and peripheral nervous systems.

  2003cited by this paper
• Neurotransmitters Mediating the Intestinal Peristaltic Reflex in the Mouse

  2003cited by this paper
• Calcitonin receptor-like receptor: identification and distribution in human peripheral tissues

  2002cited by this paper
• Expression and distribution of calcitonin receptor-like receptor in human hairy skin.

  2002cited by this paper
• Immunohistochemical Localization of Calcitonin Receptor–Like Receptor and Receptor Activity–Modifying Proteins in the Human Cerebral Vasculature

  2002cited by this paper
• Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons.

  2002cited by this paper
• Agonist-promoted Internalization of a Ternary Complex between Calcitonin Receptor-like Receptor, Receptor Activity-modifying Protein 1 (RAMP1), and β-Arrestin*

  2001cited by this paper
• Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity.

  2001cited by this paper
• Immunohistochemical detection of calcitonin gene-related peptide receptor (CGRPR)-1 in the endothelium of human coronary artery and bronchial blood vessels.

  2001cited by this paper
• Cgrp Uptake into Perivascular Capsaicin-Sensitive Nerve Terminals

  2001cited by this paper
• Pharmacological evidence for CGRP uptake into perivascular capsaicin sensitive nerve terminals

  2001cited by this paper
• A novel receptor for calcitonin gene‐related peptide (CGRP) mediates secretion in the rat colon: implications for secretory function in colitis

  2000influential reference
• Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: an autoradiographic and immunohistochemical analysis.

  2000cited by this paper
• Alleviation of mechanical and thermal allodynia by CGRP8‐37 in a rodent model of chronic central pain

  2000cited by this paper
• Activation of Intrinsic Afferent Pathways in Submucosal Ganglia of the Guinea Pig Small Intestine

  2000cited by this paper
• Receptor-activity-modifying protein 1 forms heterodimers with two G-protein-coupled receptors to define ligand recognition.

  2000cited by this paper
• CGRP-RCP, a Novel Protein Required for Signal Transduction at Calcitonin Gene-related Peptide and Adrenomedullin Receptors*

  2000cited by this paper
• Visualization of the Calcitonin Receptor-like Receptor and Its Receptor Activity-modifying Proteins during Internalization and Recycling*

  2000cited by this paper
• Receptor for calcitonin gene-related peptide: localization in the dorsal and ventral spinal cord.

  1999cited by this paper
• An Amylin Receptor Is Revealed Following Co-Transfection of a Calcitonin Receptor with Receptor Activity Modifying Proteins-1 or -3.

  1999cited by this paper
• An amylin receptor is revealed following co-transfection of a calcitonin receptor with receptor activity modifying proteins-1 or -3.

  1999cited by this paper
• Specific calcitonin gene-related peptide binding sites present throughout rat intestine.

  1999cited by this paper
• RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

  1998cited by this paper
• Monoclonal antibodies reveal expression of the CGRP receptor in Purkinje cells, interneurons and astrocytes of rat cerebellar cortex

  1998cited by this paper
• Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors.

  1997cited by this paper
• Mouse aorta: a preparation highly sensitive to the vasodilatory action of CGRP.

  1997cited by this paper
• Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay.

  1996cited by this paper
• Characterization of receptors using cyanine 3-labeled neuropeptides.

  1995cited by this paper
• Receptors for calcitonin gene related peptide (CGRP) in gastrointestinal epithelia.

  1995influential reference
• The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawal responses in rats.

  1994cited by this paper
• CGRP as a transmitter in the sensory pathway mediating peristaltic reflex.

  1994influential reference
• Distribution and binding sites of substance P and calcitonin gene-related peptide and their capsaicin-sensitivity in the spinal cord of rats and chicken: a comparative study.

  1993cited by this paper
• Monoclonal Antibody to Rat α-CGRP: Production, Characterization, and In Vivo Immunoneutralization Activity

  1993cited by this paper
• Isolation, Purification, and Biochemical Characterization of Calcitonin Gene—Related Peptide Receptors

  1992cited by this paper
• Quantitative autoradiographic distribution of calcitonin gene‐related peptide (hCGRPα) binding sites in the rat and monkey spinal cord

  1992cited by this paper
• Tachykinin and calcitonin gene-related peptide immunoreactivities and mRNAs in the mammalian enteric nervous system and sensory ganglia.

  1991cited by this paper
• Effect of neurokinin A, substance P and calcitonin gene related peptide in peripheral hyperalgesia in the rat paw.

  1991cited by this paper
• Calcitonin gene-related peptide action on intestinal circular muscle.

  1989cited by this paper
• Effects of α‐ and β‐calcitonin gene‐related peptides upon ion transport in rat descending colon

  1989influential reference
• Calcitonin gene-related peptide-alpha receptor binding sites in the gastrointestinal tract.

  1989cited by this paper
• Antinociceptive effect of intrathecally administered antiserum against calcitonin gene-related peptide on thermal and mechanical noxious stimuli in experimental hyperalgesic rats.

  1989cited by this paper
• Effects of alpha- and beta-calcitonin gene-related peptides upon ion transport in rat descending colon.

  1989influential reference
• Human α-calcitonin gene-related peptide influences colonic secretion by acting on myenteric neurons

  1989cited by this paper
• Distribution of neurons expressing calcitonin gene-related peptide mRNAs in the brain stem, spinal cord and dorsal root ganglia of rat and guinea-pig.

  1989cited by this paper
• Calcitonin gene-related peptide-α receptor binding sites in the gastrointestinal tract

  1989cited by this paper
• Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats.

  1987cited by this paper
• Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats.

  1987cited by this paper
• Calcitonin gene-related peptide excites myenteric neurons.

  1986cited by this paper
• Calcitonin gene-related peptide is a potent vasodilator

  1985influential reference
• Calcitonin gene-related peptide is a potent inhibitor of substance P degradation.

  1985cited by this paper
• Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide.

  1985cited by this paper
• Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species

  1984cited by this paper
• Alternative RNA processing: determining neuronal phenotype.

  1984cited by this paper
• Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

  1983cited by this paper
• Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

  1982cited by this paper

• Conductive hydrogel luminal filler for peripheral nerve regeneration.

  2025cites this paper
• Pharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism

  2024cites this paper
• Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia

  2024cites this paper
• Novel insight into atogepant mechanisms of action in migraine prevention

  2024cites this paper
• Mucosal neuroimmune mechanisms in gastro-oesophageal reflux disease (GORD) pathogenesis

  2024cites this paper
• Shared and independent roles of CGRP and PACAP in migraine pathophysiology

  2023cites this paper
• Nutrition and Calcitonin Gene Related Peptide (CGRP) in Migraine

  2023cites this paper
• Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists

  2022cites this paper
• Multi-omics integration reveals a six-malignant cell maker gene signature for predicting prognosis in high-risk neuroblastoma

  2022cites this paper
• Galcanezumab modulates Capsaicin-induced C-fiber reactivity

  2022cites this paper
• Itch receptor MRGPRX4 interacts with the receptor activity–modifying proteins

  2022cites this paper
• CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond.

  2022cites this paper
• Beyond CGRP: The calcitonin peptide family as targets for migraine and pain

  2021cites this paper
• Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons

  2021cites this paper
• The Cardiopulmonary Effects of the Calcitonin Gene-related Peptide Family.

  2020cites this paper
• The effects of CGRP in vascular tissue - classical vasodilation and multiple shadowed effects.

  2020cites this paper
• Glucagon like peptide 1 and glucose-dependent insulinotropic polypeptide stimulate the release of substance P from TRPV1 and TRPA1 expressing sensory nerves.

  2020cites this paper
• Age‐related molecular changes in the lumbar dorsal root ganglia of mice: Signs of sensitization, and inflammatory response

  2020cites this paper
• DISTRIBUTION OF MEMBERS OF THE CGRP FAMILY

  2020cites this paper
• The Cardiopulmonary Effects of Calcitonin-Gene Related Peptide Family

  2019cites this paper
• Molecular studies of CGRP and the CGRP family of peptides in the central nervous system

  2019cites this paper
• Amylin, a peptide expressed by nociceptors, modulates chronic neuropathic pain

  2019influential citation
• Role of intraganglionic transmission in the trigeminovascular pathway

  2019cites this paper
• Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

  2019cites this paper
• Effects of monoclonal antagonist antibodies on calcitonin gene-related peptide receptor function and trafficking

  2019cites this paper
• A potent fluorescent calcitonin gene‐related peptide analogue enables visualization of receptor internalization

  2019cites this paper
• Optogenetic Inhibition of CGRPα Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain

  2018cites this paper
• Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25

  2018cites this paper
• An Intraperitoneal Treatment with Calcitonin Gene-Related Peptide (CGRP) Regulates Appetite, Energy Intake/Expenditure, and Metabolism

  2018cites this paper
• Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons

  2018cites this paper
• CGRP Receptor Signalling Pathways.

  2018cites this paper
• Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone

  2018cites this paper
• Role of mast cells and basophils in pruritus

  2018cites this paper
• Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors

  2018cites this paper
• Calcitonin gene-related peptide and pain: a systematic review

  2017cites this paper
• CGRP and its receptors

  2017cites this paper
• Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

  2017cites this paper
• The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

  2017cites this paper
• RAMP1 suppresses mucosal injury from dextran sodium sulfate‐induced colitis in mice

  2017cites this paper
• Runx1 contributes to the functional switching of bone morphogenetic protein 4 (BMP4) from neurite outgrowth promoting to suppressing in dorsal root ganglion.

  2016cites this paper
• Amylin modulates the formalin‐induced tonic pain behaviours in rats

  2016cites this paper
• Localization of CGRP receptor components and receptor binding sites in rhesus monkey brainstem: A detailed study using in situ hybridization, immunofluorescence, and autoradiography

  2016cites this paper
• Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies.

  2016influential citation
• Effects of intermedin on dorsal root ganglia in the transmission of neuropathic pain in chronic constriction injury rats

  2015cites this paper
• Calcitonin gene‐related peptide in the joint: contributions to pain and inflammation

  2015cites this paper
• activityganglion do not control spinal trigeminal Calcitonin gene-related peptide receptors in rat

  2015cites this paper
• Adrenomedullin and the calcitonin receptor-like receptor system mRNA expressions in the rat heart and sensory ganglia in experimentally-induced long-term diabetes.

  2014cites this paper
• Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.

  2014cites this paper
• Localization of receptors for calcitonin-gene-related peptide to intraganglionic laminar endings of the mouse esophagus: peripheral interaction between vagal and spinal afferents?

  2014cites this paper
• Peripheral Calcitonin Gene-Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain

  2014cites this paper
• Feeding-dependent activation of enteric cells and sensory neurons by lymphatic fluid: evidence for a neurolymphocrine system.

  2014cites this paper
• The role of calcitonin gene-related peptide in the endothelin-1 mediated pain perception

  2013cites this paper
• Involvement of PKA-dependent upregulation of nNOS-CGRP in adrenomedullin-initiated mechanistic pathway underlying CFA-induced response in rats.

  2013cites this paper
• Calcitonin Gene-Related Peptide Receptor Antagonists: Beyond Migraine Pain—A Possible Analgesic Strategy for Osteoarthritis?

  2013cites this paper
• Expression of calcitonin gene-related peptide receptor subunits in cultured neurons following morphine treatment.

  2013cites this paper
• Protective effects of intermedin on cardiovascular, pulmonary and renal diseases: comparison with adrenomedullin and CGRP.

  2013cites this paper
• The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats

  2013cites this paper
• Distribution of CGRP and CGRP receptor in the trigeminovascular system and CNS

  2013cites this paper
• Characterisation of the Molecular Mechanisms Regulating the Signalling and Post-endocytic sorting of the Receptors for Calcitonin Gene-Related Peptide and Adsenomedullin

  2013cites this paper
• Angiotensin-(1–7) Induces Peripheral Antinociception through Mas Receptor Activation in an Opioid-Independent Pathway

  2012cites this paper
• Calcitonin gene-related peptide receptors in rat trigeminal ganglion do not control spinal trigeminal activity.

  2012cites this paper
• Endosomal proteolysis regulates calcitonin gene‐related peptide responses in mesenteric arteries

  2012influential citation
• Localization of calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1) in human gastrointestinal tract.

  2012influential citation
• Differential effects of calcitonin gene‐related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat

  2012cites this paper
• Local injection of dsRNA targeting calcitonin receptor-like receptor (CLR) ameliorates Clostridium difficile toxin A-induced ileitis

  2012cites this paper
• Enteric neuropathy evoked by repeated cisplatin in the rat

  2011cites this paper
• Human tRNA genes function as chromatin insulators

  2011cites this paper
• Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level

  2011cites this paper
• CGRP1 receptor activation induces piecemeal release of protease‐1 from mouse bone marrow‐derived mucosal mast cells

  2011cites this paper
• Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion.

  2010cites this paper
• Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

  2010influential citation
• A Role for Protein Kinase C-Dependent Upregulation of Adrenomedullin in the Development of Morphine Tolerance in Male Rats

  2010cites this paper
• Examination of molecular recognition in protein-ligand interactions: Prospective study and methods development

  2010cites this paper
• Amylin suppresses acetic acid-induced visceral pain and spinal c-fos expression in the mouse.

  2010cites this paper
• Genetic Regulation of CGRP and Its Actions

  2010cites this paper
• CGRP and Adrenomedullin as Pain-Related Peptides

  2010cites this paper
• Lipopolysaccharide induces calcitonin gene‐related peptide in the RAW264.7 macrophage cell line

  2010cites this paper
• Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats

  2010cites this paper
• Calcitonin gene-related peptide: an update on the biology

  2009cites this paper
• CGRP in Spinal Cord Pain Mechanisms

  2009influential citation
• Genetic enhancement of calcitonin gene-related Peptide-induced central sensitization to mechanical stimuli in mice.

  2009influential citation
• Upregulation of adrenomedullin in the spinal cord and dorsal root ganglia in the early phase of CFA‐induced inflammation in rats

  2009cites this paper
• Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease‐activated receptor 2

  2009cites this paper
• Enkephalins, dynorphins, and β‐endorphin in the rat dorsal horn: An immunofluorescence colocalization study

  2009cites this paper
• Early and late contributions of glutamate and CGRP to mechanical sensitization by endothelin-1.

  2009cites this paper
• Expression and transport of Angiotensin II AT1 receptors in spinal cord, dorsal root ganglia and sciatic nerve of the rat.

  2008cites this paper
• Functional Antagonism between Endogenous Neuropeptide Y and Calcitonin Gene-Related Peptide in Mesenteric Resistance Arteries

  2008cites this paper
• Increased expression of CGRP in sensory afferents of arthritic mice--effect of genetic deletion of the vanilloid receptor TRPV1.

  2008cites this paper
• Calcitonin receptor‐like receptor (CLR), receptor activity‐modifying protein 1 (RAMP1), and calcitonin gene‐related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution

  2008influential citation
• Intermedin (adrenomedullin‐2): a novel counter‐regulatory peptide in the cardiovascular and renal systems

  2008cites this paper
• Mechanisms Mediating the Enhanced Gene Transcription of P2X3 Receptor by Calcitonin Gene-related Peptide in Trigeminal Sensory Neurons*

  2008cites this paper
• Post-endocytic Sorting of Calcitonin Receptor-like Receptor and Receptor Activity-modifying Protein 1*

  2007cites this paper
• Calcitonin Receptor-Like Receptor and Receptor Activity Modifying Protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic α2C receptors

  2007cites this paper
• Role of calcitonin receptor-like receptor in colonic motility and inflammation.

  2007cites this paper
• Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate (HRS) Mediates Post-endocytic Trafficking of Protease-activated Receptor 2 and Calcitonin Receptor-like Receptor*

  2007cites this paper
• Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.

  2007cites this paper
• Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and β-arrestins

  2007influential citation
• Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain‐related sensitization of amygdala neurons

  2007influential citation
• Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors.

  2007cites this paper
• The calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS reduces neurogenic increases in dural blood flow.

  2007cites this paper