Sinus Infections, Inflammation, and Asthma

There is an important link between the upper and lower respiratory tracts whereby inflammation in one environment can influence the other. In acute rhinosinusitis, pathogen exposures are the primary driver for inflammation in the nose, which can exacerbate asthma. In chronic rhinosinusitis, a disease clinically associated with asthma, the inflammation observed is likely from a combination of an impaired epithelial barrier, dysregulated immune response, and potentially infection (or colonization) by specific pathogens. This review explores the associations between rhinosinusitis and asthma, with particular emphasis placed on the role of infections and inflammation.

• Publication year

  2019

• Venue

  Immunology and allergy clinics of North America

• Publication date

  2019-05-16

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.iac.2019.03.008PMID 31284929PMCID 7172505
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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