Collagen Type I &agr;2 (COL1A2) Is the Susceptible Gene for Intracranial Aneurysms

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Stroke

• Publication date

  2004-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.STR.0000110788.45858.DCPMID 14739420
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association of positional and functional candidate genes FGF1, FBN2, and LOX on 5q31 with intracranial aneurysm

  2003cited by this paper
• The chain register in heterotrimeric collagen peptides affects triple helix stability and folding kinetics.

  2002cited by this paper
• Mapping the Ligand-binding Sites and Disease-associated Mutations on the Most Abundant Protein in the Human, Type I Collagen*

  2002cited by this paper
• Type I collagen is thermally unstable at body temperature

  2002cited by this paper
• Ultrastructural Connective Tissue Aberrations in Patients With Intracranial Aneurysms

  2002cited by this paper
• Order of intron removal influences multiple splice outcomes, including a two-exon skip, in a COL5A1 acceptor-site mutation that results in abnormal pro-alpha1(V) N-propeptides and Ehlers-Danlos syndrome type I.

  2002cited by this paper
• Molecular Anatomy of an Intracranial Aneurysm: Coordinated Expression of Genes Involved in Wound Healing and Tissue Remodeling

  2001cited by this paper
• Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11.

  2001cited by this paper
• How many diseases does it take to map a gene with SNPs?

  2000cited by this paper
• Prevalence of intracranial saccular aneurysms in a Japanese community based on a consecutive autopsy series during a 30-year observation period. The Hisayama study.

  1999cited by this paper
• Prevalence and risk of rupture of intracranial aneurysms: a systematic review.

  1998cited by this paper
• Genetics of intracranial aneurysms.

  1997cited by this paper
• Matrix metalloproteinase-9 in cerebral aneurysms.

  1997cited by this paper
• The human type I collagen mutation database

  1997cited by this paper
• The Future of Genetic Studies of Complex Human Diseases

  1996cited by this paper
• Collagens: molecular biology, diseases, and potentials for therapy.

  1995cited by this paper
• Study of aneurysmal subarachnoid hemorrhage in Izumo City, Japan.

  1995cited by this paper
• Sudden death from aneurysmal subarachnoid hemorrhage

  1995cited by this paper
• On the Inheritance of Intracranial Aneurysms

  1994cited by this paper
• Clinical course of spontaneous subarachnoid hemorrhage

  1993cited by this paper
• Lethal perinatal osteogenesis imperfecta due to a type I collagen α2(I) gly to arg substitution detected by chemical cleavage of an mRNA:cDNA sequence mismatch

  1992cited by this paper
• A mutation in the pro alpha 2(I) gene (COL1A2) for type I procollagen in Ehlers-Danlos syndrome type VII: evidence suggesting that skipping of exon 6 in RNA splicing may be a common cause of the phenotype.

  1991cited by this paper
• Incidence and prognosis of subarachnoid hemorrhage in a Japanese rural community.

  1989cited by this paper
• Localization of collagen types I, III, IV and V, fibronectin and laminin in human arteries by the indirect immunofluorescence method.

  1986cited by this paper
• SOME PATIENTS WITH CEREBRAL ANEURYSMS ARE DEFICIENT IN TYPE III COLLAGEN

  1981cited by this paper
• The triple helix in equilibrium with coil conversion of collagen-like polytripeptides in aqueous and nonaqueous solvents. Comparison of the thermodynamic parameters and the binding of water to (L-Pro-L-Pro-Gly)n and (L-Pro-L-Hyp-Gly)n.

  1977cited by this paper
• The triple helix ⇌ coil conversion of collagen‐like polytripeptides in aqueous and nonaqueous solvents. Comparison of the thermodynamic parameters and the binding of water to (L‐Pro‐L‐Pro‐Gly)n and (L‐Pro‐L‐Hyp‐Gly)n

  1977cited by this paper
• Linkage disequilibrium in finite populations

  1968cited by this paper
• The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models.

  1964cited by this paper

• The Impact of Selected COL1A1 and COL1A2 Gene Polymorphisms on Bone Mineral Density and the Risk of Metabolic Diseases in Postmenopausal Women

  2025cites this paper
• Intracranial aneurysm as a possible complication of osteogenesis imperfecta: a case series and literature review.

  2023cites this paper
• Influence of type I collagen polymorphisms and risk of anterior cruciate ligament rupture in athletes: a case-control study

  2022cites this paper
• Genetic Polymorphisms in COL1A2 gene and the Risk of Tendinopathy: Case-Control Study

  2022cites this paper
• Clinical and molecular features of patients with COL1 ‐related disorders: Implications for the wider spectrum and the risk of vascular complications

  2022cites this paper
• Proteomic Analysis Reveals that Di Dang Decoction Protects Against Acute Intracerebral Hemorrhage Stroke in Rats by Regulating S100a8, S100a9 Col1a1, and Col1a2

  2021cites this paper
• Understanding the genetics of intracranial aneurysms: A primer.

  2021cites this paper
• COL1A2 Polymorphism contributes to Oral submucous fibrosis: A possible role in inducing alternative splicing in areca chewers

  2021cites this paper
• Presence of Type 1 Collagen Alpha-2 (COL1A2) (rs42524) Gene Polymorphism and Scar Tissue Formation in Different Areas of Head and Neck

  2020cites this paper
• Differential Protein Expression between Cystic and Solid Vestibular Schwannoma Using Tandem Mass Tag‐Based Quantitative Proteomic Analysis

  2020cites this paper
• COL1A1 polymorphism and neurological complications in pediatric acute lymphoblastic leukemia patients and their associations with altered bone mineral density

  2020cites this paper
• Molecular basis of stroke

  2020cites this paper
• Aneurysm Formation, Growth and Rupture: The Biology and Physics of Cerebral Aneurysms.

  2019cites this paper
• Association between col1a2 Polymorphism and the Occurrence of Pelvic Organ Prolapse in Brazilian Women

  2019cites this paper
• Insertion/deletion polymorphism in the 3′ untranslated region of COL1A2 disrupts its interaction with microRNA‐382 and leads to decreased susceptibility to osteoporotic fracture

  2019cites this paper
• The association between collagen gene polymorphisms and intracranial aneurysms: a meta-analysis

  2019cites this paper
• Collagen type-I A2 gene polymorphisms and susceptibility to intracranial aneurysms: a meta-analysis of genetic association studies

  2018cites this paper
• Neuropathology of cerebrovascular diseases.

  2017cites this paper
• Collagen Type I Alpha 2 (COL1A2) Polymorphism Contributes to Intracranial Aneurysm Susceptibility: A Meta-Analysis

  2017influential citation
• Ruptured intracranial aneurysm in patients with osteogenesis imperfecta: 2 familial cases and a systematic review of the literature.

  2016cites this paper
• Association between COL 1 A 2 gene polymorphisms and susceptibility to the intracerebral hemorrhage in a Chinese population

  2016cites this paper
• Influence of COL1A2 gene variants on the incidence of hypertensive intracerebral hemorrhage in a Chinese population.

  2016cites this paper
• Identification of transcription factors and gene clusters in rabbit smooth muscle cells during high flow-induced vascular remodeling via microarray.

  2016cites this paper
• Molecular Mechanisms of the Formation and Progression of Intracranial Aneurysms

  2015cites this paper
• Mutation spectrum of COL1A1 and COL1A2 genes in Indian patients with osteogenesis imperfecta

  2014cites this paper
• Associations of collagen type I α2 polymorphisms with the presence of intracranial aneurysms in patients from Germany.

  2014cites this paper
• Subarachnoid hemorrhage secondary to a ruptured middle cerebral aneurysm in a patient with osteogenesis imperfecta: a case report

  2014cites this paper
• Genes Mediating Cardiac Remodeling During Pregnancy and the Early Post-Partum-Period in Mice

  2014cites this paper
• Genetic risk factors for intracranial aneurysms

  2013cites this paper
• Genetic and Therapeutic Studies

  2013cites this paper
• Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome

  2013cites this paper
• in more than 116,000 individuals Genetic risk factors for intracranial aneurysms: A meta-analysis

  2013cites this paper
• Is type I alpha 2 collagen gene responsible for intracranial aneurysm in Northeast China?

  2013cites this paper
• The rs42524 COL1A2 polymorphism is associated with primary intracerebral hemorrhage in a Chinese population.

  2012cites this paper
• COL1A2 polymorphic markers confer an increased risk of neovascular age-related macular degeneration in a Han Chinese population

  2012cites this paper
• A functional variant of the collagen type III alpha1 gene modify risk of sporadic intracranial aneurysms

  2012cites this paper
• Molecular Genetics of Stroke

  2012cites this paper
• On the genetics of intracranial aneurysms and on growth factor induced angiogenesis in the murine brain

  2012cites this paper
• 66 – Genetics of Aneurysms and Arteriovenous Malformations

  2011cites this paper
• Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers

  2011cites this paper
• Molecular basis for the development of intracranial aneurysm

  2010cites this paper
• Toole's Cerebrovascular Disorders: Hematological Disorders and Hypercoagulable States

  2010cites this paper
• Toole's Cerebrovascular Disorders: Subarachnoid Hemorrhage and Aneurysms

  2010cites this paper
• CHARACTERIZING A NOVEL GENETIC LOCUS ASSOCIATED WITH FAMILIAL CO-OCCURRENCE OF THORACIC AORTIC ANEURYSMS AND INTRACRANIAL ANEURYSMS

  2010cites this paper
• Genetics of Aneurysmal Disease: The Dogs That Did Not Bark

  2010cites this paper
• Clinical genetic issues in stroke.

  2009cites this paper
• Proinflammatory phenotype with imbalance of KLF2 and RelA: Risk of childhood stroke with sickle cell anemia

  2009cites this paper
• The role of collagen type I alpha2 polymorphisms: intracranial aneurysms in Koreans.

  2009cites this paper
• Does COLIA1 SP1-binding site polymorphism predispose women to pelvic organ prolapse?

  2009cites this paper
• Microsurgical Aneurysm Model in Rats and Mice: Development of Endovascular Treatment and Optimization of Magnetic Resonance Imaging

  2009cites this paper
• Heterozygosity for a coding SNP in COL1A2 confers a lower BMD and an increased stroke risk.

  2009cites this paper
• Transcriptome-Wide Characterization of Gene Expression Associated with Unruptured Intracranial Aneurysms

  2009cites this paper
• The interleukin-6 gene -572G>C promoter polymorphism is related to intracranial aneurysms in Chinese Han nationality.

  2008cites this paper
• Suggestive Loci for Intracranial Aneurysms Chromosome 1

  2008cites this paper
• The influence of genetics on intracranial aneurysm formation and rupture: current knowledge and its possible impact on future treatment.

  2008cites this paper
• Candidate Cell and Matrix Interaction Domains on the Collagen Fibril, the Predominant Protein of Vertebrates*

  2008cites this paper
• TNF-α-mediated inflammation in cerebral aneurysms: A potential link to growth and rupture

  2008cites this paper
• Molecular Genetics of Human Intracranial Aneurysms

  2008cites this paper
• Polymorphism rs42524 of COL1A2 and sporadic intracranial aneurysms in the Chinese population.

  2008cites this paper
• Association analyses confirming a susceptibility locus for intracranial aneurysm at chromosome 14q23

  2008influential citation
• Genetics of Intracranial Aneurysms

  2008cites this paper
• Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in rats

  2008cites this paper
• Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms

  2007cites this paper
• GENETICS OF INTRACRANIAL ANEURYSMS

  2007cites this paper
• A novel arterial pouch model of saccular aneurysm by concomitant elastase and collagenase digestion

  2007cites this paper
• Hemorrhagic Brain Disease

  2007cites this paper
• Cerebral aneurysms in a patient with osteogenesis imperfecta and exon 28 polymorphism of COL1A2.

  2007cites this paper
• Model-Based Linkage Analyses Confirm Chromosome 19q13.3 as a Susceptibility Locus for Intracranial Aneurysm

  2007cites this paper
• Chondroitin Sulfate Proteoglycan 2 (CSPG2) Gene Polymorphisms rs173686 and rs251124 are not Associated with Intracranial Aneurysms in Chinese Han Nationality

  2007cites this paper
• Risk factors for intracranial aneurysm in a Chinese ethnic population.

  2006cites this paper
• Genetic Analysis of Familial Connective Tissue Alterations Associated With Cervical Artery Dissections Suggests Locus Heterogeneity

  2006cites this paper
• Mice with a deletion in the first intron of the Col1a1 gene develop dissection and rupture of aorta in the absence of aneurysms: High‐resolution magnetic resonance imaging, at 4.7 T, of the aorta and cerebral arteries

  2006cites this paper
• A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.

  2006cites this paper
• Search on Chromosome 17 Centromere Reveals TNFRSF13B as a Susceptibility Gene for Intracranial Aneurysm: A Preliminary Study

  2006cites this paper
• The genetics of intracranial aneurysms

  2006cites this paper
• Phenytoin and cognitive decline.

  2005cites this paper
• CORRECTION

  2005cites this paper
• What are high-flow and low-flow oxygen delivery systems?

  2005cites this paper
• Thromboprophylaxis in stroke patients.

  2005cites this paper
• Update on the genetics of stroke and cerebrovascular disease 2004.

  2005cites this paper
• Genetics of intracranial aneurysms.

  2005cites this paper
• Expression of Structural Proteins and Angiogenic Factors in Normal Arterial and Unruptured and Ruptured Aneurysm Walls

  2005cites this paper
• What Causes the Acute Blood Pressure Elevation After Stroke? * Response:

  2005cites this paper
• Impact of surgical treatment of unruptured aneurysms.

  2005cites this paper
• What causes the acute blood pressure elevation after stroke?

  2005cites this paper
• VEGF plasma levels in nonruptured intracranial aneurysms

  2005cites this paper
• [Unruptured cerebral aneurysms].

  2005cites this paper
• Collagen morphology is not associated with the Ala549Pro polymorphism of the COL1A2 gene.

  2005cites this paper
• Update on genetics of stroke and cerebrovascular disease 2005.

  2005cites this paper
• Recovery from aphasia after decompressive surgery in patients with dominant hemispheric infarction.

  2005cites this paper
• Nanometer-sized gelatin particles prepared by means of gamma-ray irradiation

  2004cites this paper
• From intracranial aneurysm to subarachnoid hemorrhage : unraveling the genetics

  2004cites this paper