The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2003-07-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.1533295100PMID 12878730PMCID PMC170922
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• IN VIVO BLOCKADE OF MACROPHAGE MIGRATION INHIBITORY FACTOR PREVENTS SKIN GRAFT DESTRUCTION AFTER INDIRECT ALLORECOGNITION1

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  2001cited by this paper
• Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53.

  2000cited by this paper
• Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

  2000cited by this paper
• Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia

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• Helicobacter pylori infection is the primary cause of gastric cancer.

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• Surfing the p53 network

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• Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with adenocarcinoma of the lung

  2000cited by this paper
• Enhancement of macrophage migration inhibitory factor (MIF) expression in injured epidermis and cultured fibroblasts.

  2000cited by this paper
• NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.

  2000cited by this paper
• Analysis of p53-regulated gene expression patterns using oligonucleotide arrays.

  2000cited by this paper
• Increased Stability of Macrophage Migration Inhibitory Factor (MIF) in DU-145 Prostate Cancer Cells

  2000cited by this paper
• Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control.

  2000cited by this paper
• The p53 pathway

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• The molecular characterization of the fetal stem cell marker AA4.

  1999cited by this paper
• ras activity and cyclin D1 expression: An essential mechanism of mouse skin tumor development

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• Macrophage migration inhibitory factor: cytokine, hormone, or enzyme?

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• A Proinflammatory Cytokine Inhibits P53 Tumor Suppressor Activity

  1999cited by this paper
• Targeted Disruption of Migration Inhibitory Factor Gene Reveals Its Critical Role in Sepsis

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• Expression pattern of macrophage migration inhibitory factor during embryogenesis.

  1999cited by this paper
• At the Crossroads of Inflammation and Tumorigenesis

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• Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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• DNA sequence motifs are associated with aberrant homologous recombination in the mouse macrophage migration inhibitory factor (Mif) locus.

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  1998cited by this paper
• The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat

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• Enhanced expression of macrophage migration inhibitory factor in prostatic adenocarcinoma metastases.

  1996cited by this paper
• Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene‐mediated apoptosis.

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• Preferential Formation of Benzo[a]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

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• p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement

  1996cited by this paper
• E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

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• Genetic and non-genetic biomarkers related to carcinogenesis in evaluating toxicological risk from Fenarimol.

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• Site-specific induction and repair of benzo[a]pyrene diol epoxide DNA damage in human H-ras protooncogene as revealed by restriction cleavage inhibition.

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• Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

  1996cited by this paper
• Mutations in the p53 and SCID genes cooperate in tumorigenesis.

  1996cited by this paper
• Conditional gene targeting.

  1996cited by this paper
• Long-range disruption of gene expression by a selectable marker cassette.

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• Characterization of transcription factor E2F complexes during muscle and neuronal differentiation.

  1995cited by this paper
• MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia

  1995cited by this paper
• Tumor spectrum analysis in p53-mutant mice.

  1994cited by this paper
• Cell cycle-specific association of E2F with the p130 E1A-binding protein.

  1993cited by this paper
• A macrophage migration inhibitory factor is expressed in the differentiating cells of the eye lens.

  1993cited by this paper
• Interactions of the p107 and Rb proteins with E2F during the cell proliferation response.

  1993cited by this paper
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• Nitric oxide-mediated apoptosis in murine peritoneal macrophages.

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• MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia

  1993cited by this paper
• Nitric oxide synthase induces macrophage death by apoptosis.

  1993cited by this paper
• Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.

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