Sawada et al. report that Resolvin E1 (RvE1) down-regulates DC motility in both steady state and inflammatory conditions in the skin and exerts its antiinflammatory effects in contact hypersensitivity. They propose the LTB4-BLT1 signaling blockade as a possible major mechanism through which RvE1 exerts its regulatory effects.
Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses
Y. Sawada,T. Honda,S. Hanakawa,S. Nakamizo,T. Murata,Yuri Ueharaguchi-Tanada,S. Ono,Wataru Amano,Saeko Nakajima,G. Egawa,H. Tanizaki,A. Otsuka,A. Kitoh,T. Dainichi,N. Ogawa,Yuichi Kobayashi,T. Yokomizo,M. Arita,Motonobu Nakamura,Y. Miyachi,K. Kabashima
Published 2015 in Journal of Experimental Medicine
ABSTRACT
PUBLICATION RECORD
- Publication year
2015
- Venue
Journal of Experimental Medicine
- Publication date
2015-10-19
- Fields of study
Biology, Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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- No concepts are published for this paper.
REFERENCES
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