Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men

T. Snijders,J. Nederveen,S. Joanisse,Marika Leenders,L. Verdijk,L. V. van Loon,G. Parise

Published 2016 in Journal of Cachexia, Sarcopenia and Muscle

ABSTRACT

Adequate muscle fibre perfusion is critical for the maintenance of muscle mass; it is essential in the rapid delivery of oxygen, nutrients and growth factors to the muscle, stimulating muscle fibre growth. Muscle fibre capillarization is known to decrease substantially with advancing age. However, whether (relative) low muscle fibre capillarization negatively impacts the muscle hypertrophic response following resistance exercise training in older adults is unknown.

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