Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Cell

• Publication date

  1997-04-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0092-8674(00)80185-3PMID 9094717
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Hansenula polymorpha PEX14 gene encodes a novel peroxisomal membrane protein essential for peroxisome biogenesis

  1997cited by this paper
• Peb1p (Pas7p) is an intraperoxisomal receptor for the NH2-terminal, type 2, peroxisomal targeting sequence of thiolase: Peb1p itself is targeted to peroxisomes by an NH2-terminal peptide

  1996cited by this paper
• A unified nomenclature for peroxisome biogenesis factors

  1996cited by this paper
• Minding your p's and q's

  1996cited by this paper
• The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins

  1996cited by this paper
• Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor

  1996influential reference
• The targeting and assembly of peroxisomal proteins: some old rules do not apply.

  1996cited by this paper
• Prediction and analysis of coiled-coil structures.

  1996influential reference
• Convergence of model systems for peroxisome biogenesis.

  1996cited by this paper
• Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor

  1996cited by this paper
• Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor

  1996influential reference
• Identification of a yeast peroxisomal member of the family of AMP-binding proteins.

  1996cited by this paper
• The import receptor for the peroxisomal targeting signal 2 (PTS2) in Saccharomyces cerevisiae is encoded by the PAS7 gene.

  1996influential reference
• Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders

  1995cited by this paper
• How proteins penetrate peroxisomes.

  1995cited by this paper
• Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders

  1995cited by this paper
• Predicting coiled coils by use of pairwise residue correlations.

  1995influential reference
• Pmp27 promotes peroxisomal proliferation

  1995cited by this paper
• PEB1 (PAS7) in Saccharomyces cerevisiae encodes a hydrophilic, intra- peroxisomal protein that is a member of the WD repeat family and is essential for the import of thiolase into peroxisomes

  1995cited by this paper
• Pay32p of the yeast Yarrowia lipolytica is an intraperoxisomal component of the matrix protein translocation machinery

  1995cited by this paper
• Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p

  1995influential reference
• The Hansenula polymorpha PER3 Gene Is Essential for the Import of PTS1 Proteins into the Peroxisomal Matrix (*)

  1995cited by this paper
• Purification and immunolocalization of the peroxisomal 3‐oxoacyl‐coA thiolase from Saccharomyces cerevisiae

  1994cited by this paper
• The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL.

  1994cited by this paper
• PAS7 encodes a novel yeast member of the WD‐40 protein family essential for import of 3‐oxoacyl‐CoA thiolase, a PTS2‐containing protein, into peroxisomes.

  1994influential reference
• The peroxisomal targeting signal of 3‐oxoacyl‐coA thiolase from Saccharomyces cerevisiae

  1994cited by this paper
• Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo.

  1994cited by this paper
• PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae.

  1993cited by this paper
• Protein import into peroxisomes and biogenesis of the organelle.

  1993cited by this paper
• Two complementary approaches to study peroxisome biogenesis in Saccharomyces cerevisiae: forward and reversed genetics.

  1993cited by this paper
• Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.

  1992cited by this paper
• PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis

  1991cited by this paper
• MINDING YOUR P'S AND Q'S

  1991cited by this paper
• PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases.

  1991cited by this paper
• Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

  1990cited by this paper
• Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae.

  1989influential reference
• A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

  1989influential reference
• KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene.

  1989cited by this paper
• New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites.

  1988cited by this paper
• Antibodies: A Laboratory Manual

  1988cited by this paper
• Proliferation of microbodies in Saccharomyces cerevisiae

  1987influential reference
• Two nuclear mutations that block mitochondrial protein import in yeast.

  1984cited by this paper

• Motif-guided trafficking of leishmanial PAS domain-containing phosphoglycerate kinase into glycosomes and lysosomes.

  2026cites this paper
• Integrative Omics reveals changes in the cellular landscape of peroxisome-deficient pex3 yeast cells.

  2025cites this paper
• Role of AAA-ATPase Cdc48p in peroxisomal quality control.

  2025cites this paper
• Cvm1 and its paralog Cvm2 function as a complex at vacuolar membrane contact sites.

  2025cites this paper
• PEX14 condensates recruit receptor and cargo pairs for peroxisomal protein import

  2025cites this paper
• Identifying and characterizing a missing peroxin—PEX8—in Arabidopsis thaliana

  2025cites this paper
• Frontiers in the physiology of male pattern androgenetic alopecia: Beyond the androgen horizon.

  2025cites this paper
• Ribosome-binding protein 1, RRBP1, maintains peroxisome biogenesis

  2025cites this paper
• Ribosome-binding protein 1 maintains peroxisome biogenesis

  2024cites this paper
• Integrative Omics reveals changes in the cellular landscape of yeast without peroxisomes

  2024cites this paper
• The M2 Protein of the Influenza A Virus Interacts with PEX19 to Facilitate Virus Replication by Disrupting the Function of Peroxisome

  2024cites this paper
• Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

  2023cites this paper
• Analysis of Peroxisome Biogenesis by Phos-Tag SDS-PAGE.

  2023cites this paper
• The Pex6 N1 domain is required for Pex15 binding and proper assembly with Pex1

  2023cites this paper
• Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages

  2023cites this paper
• Analysis of Yeast Peroxisomes via Spatial Proteomics.

  2023cites this paper
• A novel PEX14/PEX5 interface links peroxisomal protein import and receptor recycling

  2023cites this paper
• Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma.

  2022cites this paper
• Peroxisome biogenesis initiated by protein phase separation

  2022cites this paper
• Translating the Arabidopsis thaliana Peroxisome Proteome Insights to Solanum lycopersicum: Consensus Versus Diversity

  2022cites this paper
• Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

  2022cites this paper
• Good things come to those who bait: the peroxisomal docking complex

  2022cites this paper
• PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS

  2022cites this paper
• Post‐translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism

  2021cites this paper
• Peroxin FgPEX22-Like Is Involved in FgPEX4 Tethering and Fusarium graminearum Pathogenicity

  2021cites this paper
• Unearthing LTR Retrotransposon gag Genes Co-opted in the Deep Evolution of Eukaryotes

  2021cites this paper
• The coiled-coil domain of glycosomal membrane-associated Leishmania donovani PEX14: cloning, overexpression, purification and preliminary crystallographic analysis.

  2020cites this paper
• Membrane Processing and Steady-State Regulation of the Alternative Peroxisomal Import Receptor Pex9p

  2020cites this paper
• Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility

  2020cites this paper
• A Mouse Model System to Study Peroxisomal Roles in Neurodegeneration of Peroxisome Biogenesis Disorders.

  2020cites this paper
• Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae

  2020cites this paper
• Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay

  2020cites this paper
• Pex13 and Pex14, the key components of the peroxisomal docking complex, are required for peroxisome formation, host infection and pathogenicity-related morphogenesis in Magnaporthe oryzae

  2019cites this paper
• Peroxisome protein import recapitulated in Xenopus egg extracts

  2019cites this paper
• The deubiquitination of the PTS1-import receptor Pex5p is required for peroxisomal matrix protein import.

  2019cites this paper
• Vps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner

  2019cites this paper
• The type-2 peroxisomal targeting signal.

  2019cites this paper
• Drosophila melanogaster Peroxisome Biogenesis Factor 7 plays a role in embryonic development

  2019cites this paper
• Towards the molecular architecture of the peroxisomal receptor docking complex

  2019cites this paper
• Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

  2018cites this paper
• Receptor recognition by the peroxisomal AAA complex depends on the presence of the ubiquitin moiety and is mediated by Pex1p

  2018cites this paper
• Membrane topologies of PEX13 and PEX14 provide new insights on the mechanism of protein import into peroxisomes

  2018cites this paper
• Unraveling of the Structure and Function of Peroxisomal Protein Import Machineries.

  2018cites this paper
• The Pex4p-Pex22p complex from Hansenula polymorpha: biophysical analysis, crystallization and X-ray diffraction characterization.

  2018cites this paper
• The hydrophobic region of the Leishmania peroxin 14: requirements for association with a glycosome mimetic membrane.

  2017cites this paper
• The Hydrophobic Region of the Leishmania Peroxin 14 – Requirements for 5 Association with a Glycosome Mimetic Membrane 6 7 8

  2017cites this paper
• University of Groningen Functional similarity between the peroxisomal PTS 2 receptor binding protein Pex 18 p and the N-terminal half of the PTS 1 receptor Pex 5

  2017cites this paper
• Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites

  2017cites this paper
• Pex14/17, a filamentous fungus-specific peroxin, is required for the import of peroxisomal matrix proteins and full virulence of Magnaporthe oryzae.

  2017cites this paper
• Evaluation of In Vitro Function by Subcellular Distribution of Lysosomal and Peroxisomal Protein in Saccharomyces cerevisiae.

  2017cites this paper
• An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection

  2017cites this paper
• Pnc1 piggy-back import into peroxisomes relies on Gpd1 homodimerisation

  2017cites this paper
• Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins.

  2017cites this paper
• Peroxisome biogenesis disorders

  2016cites this paper
• Enhanced lysosomal activity by overexpressed aminopeptidase Y in Saccharomyces cerevisiae

  2016cites this paper
• Einblick in den Mechanismus des Pex1p/Pex6p‐AAA\(^{+}\)‐Komplexes der peroxisomalen Matrixprotein‐Importmaschinerie mittels Struktur‐Funktionsanalysen

  2016cites this paper
• Regulation of peroxisome dynamics by phosphorylation.

  2016cites this paper
• Peroxisomal protein import pores.

  2016cites this paper
• Role of AAA(+)-proteins in peroxisome biogenesis and function.

  2016cites this paper
• Pex9p is a new yeast peroxisomal import receptor for PTS1-containing proteins

  2016influential citation
• Structural biology of the import pathways of peroxisomal matrix proteins.

  2016cites this paper
• Pex 9 p is a novel yeast peroxisomal import receptor for PTS 1-proteins

  2016influential citation
• Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery.

  2016cites this paper
• Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation

  2015cites this paper
• The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.

  2015cites this paper
• Distinct Pores for Peroxisomal Import of PTS1 and PTS2 Proteins.

  2015cites this paper
• Covalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import Interactions*

  2015cites this paper
• Evolutionary loss of peroxisomes – not limited to parasites

  2015cites this paper
• Role of Pex21p for Piggyback Import of Gpd1p and Pnc1p into Peroxisomes of Saccharomyces cerevisiae*

  2015cites this paper
• Structural Insights into Cargo Recognition by the Yeast PTS1 Receptor*

  2015cites this paper
• The Molecular Determinants of Tumor Cell Modulation of Immune Selection

  2015cites this paper
• Distinct Pores for Peroxiso mal Import of PTS 1 and PTS 2 Proteins Graphical Abstract Highlights

  2015cites this paper
• Protein Transport In and Out of Plant Peroxisomes

  2014cites this paper
• The Cytosolic Domain of Pex22p Stimulates the Pex4p-Dependent Ubiquitination of the PTS1-Receptor

  2014cites this paper
• AAA Peroxins and Their Recruiter Pex26p Modulate the Interactions of Peroxins Involved in Peroxisomal Protein Import*

  2014cites this paper
• Integrated structural biology of protein complexes in miRNA and peroxisome biogenesis

  2014cites this paper
• Distinct Modes of Ubiquitination of Peroxisome-targeting Signal Type 1 (PTS1) Receptor Pex5p Regulate PTS1 Protein Import*

  2014cites this paper
• The Matrix Protein Import Complex in Yeast

  2014cites this paper
• The functional relationship between peroxisomes, bile salts and lipid rafts in the liver

  2013cites this paper
• Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.

  2013cites this paper
• Peroxisome Biogenesis Pex19p, a Farnesylated Protein Essential for

  2013cites this paper
• A Combined Approach of Quantitative Interaction Proteomics and Live-cell Imaging Reveals a Regulatory Role for Endoplasmic Reticulum (ER) Reticulon Homology Proteins in Peroxisome Biogenesis*

  2013cites this paper
• A Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into Peroxisomes*♦

  2013cites this paper
• Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat—Store ’em Up or Burn ’em Down

  2013cites this paper
• The Mechanism of ER to Cytosol Retrotranslocation of Proteins Targeted to ERAD (ER Associated Degradation)

  2013cites this paper
• The RING‐type ubiquitin ligases Pex2p, Pex10p and Pex12p form a heteromeric complex that displays enhanced activity in an ubiquitin conjugating enzyme‐selective manner

  2012cites this paper
• Molecular basis of peroxisomal biogenesis disorders caused by defects in peroxisomal matrix protein import.

  2012cites this paper
• Visualization of microbodies in Chlamydomonas reinhardtii

  2012cites this paper
• AWP1/ZFAND6 Functions in Pex5 Export by Interacting with Cys‐Monoubiquitinated Pex5 and Pex6 AAA ATPase

  2012cites this paper
• Molecular mechanisms of peroxisome biogenesis in yeasts

  2012cites this paper
• New insights into dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p in shuttling of PTS1-receptor Pex5p during peroxisome biogenesis.

  2012cites this paper
• Peroxisome Dynamics: Molecular Players, Mechanisms, and (Dys)functions

  2012influential citation
• Pex19p Contributes to Peroxisome Inheritance in the Association of Peroxisomes to Myo2p

  2012cites this paper
• The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae.

  2012cites this paper
• PEROXISOME PROLIFERATION IN THE YEAST SACCHAROMYCES CEREVISIAE AND FUNCTIONAL ANALYSIS OF THE MEMBRANE PROTEIN PEX30P

  2011cites this paper
• Matrix proteins are inefficiently imported into Arabidopsis peroxisomes lacking the receptor-docking peroxin PEX14

  2011influential citation
• Influence of Peroxisomal Import and Receptor Recycling of Peroxisomal Function

  2011cites this paper
• Protein import machineries of peroxisomes.

  2011cites this paper
• Cysteine Ubiquitination of PTS1 Receptor Pex5p Regulates Pex5p Recycling

  2011cites this paper
• Reducing PEX13 Expression Ameliorates Physiological Defects of Late‐Acting Peroxin Mutants

  2011cites this paper