A comparison of the effects of L‐NAME, 7‐NI and L‐NIL on carrageenan‐induced hindpaw oedema and NOS activity

No abstract is available for this paper.

• Publication year

  1998

• Venue

  British Journal of Pharmacology

• Publication date

  1998-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/sj.bjp.0701735PMID 9559895PMCID PMC1565282
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nitric oxide: a key mediator in the early and late phase of carrageenan‐induced rat paw inflammation

  1996influential reference
• 7-Nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase.

  1995cited by this paper
• Nitric oxide synthase: expression and expressional control of the three isoforms

  1995cited by this paper
• Nitric oxide synthase activity is elevated in inflammatory lung disease in humans.

  1995cited by this paper
• Nitric oxide as a mediator of inflammation?—You had better believe it

  1995cited by this paper
• Modulation by nitric oxide of prostaglandin biosynthesis in the rat

  1995cited by this paper
• The nitric oxide synthase inhibitor, L-NG-monomethylarginine, reduces carrageenan-induced pleurisy in the rat.

  1995cited by this paper
• Nitric oxide up‐regulates the release of inflammatory mediators by mouse macrophages

  1995cited by this paper
• Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis.

  1995influential reference
• Inhibition of nitric oxide synthase--potential for a novel class of therapeutic agent?

  1995cited by this paper
• Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat, and human osteoblast-like cells and its functional role in osteoblast metabolic activity.

  1995cited by this paper
• In vivo cultivation of tumor cells in hollow fibers.

  1995cited by this paper
• Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism.

  1995cited by this paper
• The role of nitric oxide in inflammation.

  1995cited by this paper
• Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats.

  1995influential reference
• The Role of Nitric Oxide in Inflammation

  1995cited by this paper
• Effect of arginine analogues on rat hind paw oedema and mast cell activation in vitro.

  1994cited by this paper
• Cyclo‐oxygenase and nitric oxide synthase isoforms in rat carrageenin‐induced pleurisy

  1994cited by this paper
• Plasticity of NO synthase expression in the nervous and endocrine systems.

  1994cited by this paper
• Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.

  1994cited by this paper
• Induction of calcium-dependent nitric oxide synthases by sex hormones.

  1994cited by this paper
• The role of nitric oxide in uveitis.

  1994cited by this paper
• Primary cultures of rat islet capillary endothelial cells. Constitutive and cytokine-inducible macrophagelike nitric oxide synthases are expressed and activities regulated by glucose concentration.

  1994cited by this paper
• L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.

  1994cited by this paper
• 7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure

  1993influential reference
• Inhibition of rat cerebellar nitric oxide synthase by 7‐nitro indazole and related substituted indazoles

  1993cited by this paper
• Suppression of arthritis by an inhibitor of nitric oxide synthase

  1993influential reference
• Inflammation, immunoregulation, and inducible nitric oxide synthase

  1993cited by this paper
• Nitric oxide synthase inhibitors cause sustained, but reversible, hypertension and hindquarters vasoconstriction in Brattleboro rats.

  1992cited by this paper
• Modulation of acute inflammation by endogenous nitric oxide.

  1992influential reference
• The non‐peptide NK1 receptor antagonist, (±)‐CP‐96,345, produces antinociceptive and anti‐oedema effects in the rat

  1992cited by this paper
• Evidence that endogenous nitric oxide modulates oedema formation induced by substance P.

  1990cited by this paper
• Regional haemodynamic changes during oral ingestion of NG‐monomethyl‐l‐arginine or NG‐nitro‐l‐arginine methyl ester in conscious Brattleboro rats

  1990cited by this paper
• Vascular endothelial cells synthesize nitric oxide from L-arginine

  1988cited by this paper
• Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine

  1971cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Anti-Inflammatory Effects of Hyeonggaeyeongyo-tang: Evidence from In Vitro and In Vivo Studies

  2025cites this paper
• Insight into antioxidant and anti-inflammatory effects of marine bacterial natural exopolysaccharide (EPSSM) using carrageenan-induced paw edema in rats

  2024cites this paper
• Role of Gasotransmitters in Inflammatory Edema

  2023cites this paper
• Biological activity of algal derived carrageenan: A comprehensive review in light of human health and disease.

  2023cites this paper
• The Anti-Cancer Effect of Cinnamon Aqueous Extract: A Focus on Hematological Malignancies

  2023cites this paper
• Phenolic compounds, in vivo anti-inflammatory, analgesic and antipyretic activities of the aqueous extracts from fresh and dry aerial parts of Brocchia cinerea (Vis.).

  2022cites this paper
• RI75, a curcumin analogue, inhibits tumor necrosis factor-α and interleukin-6 production and exhibits antiallodynic and antiedematogenic activities in mice

  2022cites this paper
• New insights into geraniol’s antihemolytic, anti-inflammatory, antioxidant, and anticoagulant potentials using a combined biological and in silico screening strategy

  2022cites this paper
• Analgesic and Anti-inflammatory Activities of Trayodashang Guggulu, an Ayurvedic Formulation

  2022cites this paper
• Anti-inflammatory activities of a sulfated polysaccharide isolated from the brown seaweed Padina boergesenii (Phaeophyceae, Dictyotaceae)

  2022cites this paper
• Phytochemical Profile, Free Radical Scavenging and Anti-Inflammatory Properties of Acalypha Indica Root Extract: Evidence from In Vitro and In Vivo Studies

  2021cites this paper
• Low-intensity ultrasound attenuates paw edema formation and decreases vascular permeability induced by carrageenan injection in rats

  2020cites this paper
• Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

  2020cites this paper
• Attenuation of carrageenan-induced hind paw edema and plasma TNF-α level by Philippine stingless bee (Tetragonula biroi Friese) propolis

  2020cites this paper
• Attenuation of Inflammatory Symptoms by Icariside B2 in Carrageenan and LPS-Induced Inflammation Models via Regulation of MAPK/NF-κB Signaling Cascades

  2020cites this paper
• Analgesic, anti-inflammatory and antipyretic activities of ethanolic extract of stem bark of Anogeissus latifolia Roxb

  2020cites this paper
• Clindamycin inhibits nociceptive response by reducing tumor necrosis factor-α and CXCL-1 production and activating opioidergic mechanisms

  2019cites this paper
• Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

  2019cites this paper
• Anti-Inflammatory Activities of Leaf Oil from Cinnamomum subavenium In Vitro and In Vivo

  2019cites this paper
• Protopine attenuates inflammation stimulated by carrageenan and LPS via the MAPK/NF-κB pathway.

  2019cites this paper
• The nickel-catalyzed C3-acylation of 2H-indazoles with aldehydes.

  2019cites this paper
• Anti-inflammatory and antioxidant activities of Inula viscosa and Senecio anteuphorbium

  2018cites this paper
• Carrageenan: a review.

  2018influential citation
• Amelioration of inflammatory responses by Socheongryong-Tang, a traditional herbal medicine, in RAW 264.7 cells and rats

  2018cites this paper
• Targeting the NMDA receptor/NO signalling pathway following L-α aminoadipic acid-induced astrocytic impairment and associated changes in the structural plasticity of neurons

  2018cites this paper
• 21‐Benzylidene digoxin, a novel digoxin hemi‐synthetic derivative, presents an anti‐inflammatory activity through inhibition of edema, tumour necrosis factor alpha production, inducible nitric oxide synthase expression and leucocyte migration

  2018cites this paper
• Attenuation of inflammatory responses by (+)-syringaresinol via MAP-Kinase-mediated suppression of NF-κB signaling in vitro and in vivo

  2018cites this paper
• Experimental Models of Rheumatoid Arthritis: Acute and Chronic Pain

  2017cites this paper
• In vitro assesment of anti-inflammatory activities of coumarin and Indonesian cassia extract in RAW264.7 murine macrophage cell line

  2017cites this paper
• Potent anti-nociceptive and anti-inflammatory effects of methanol fraction of Otostegia persica extract and its components

  2017cites this paper
• Anti-inflammatory effects and anti-oxidant capacity of Myrathius arboreus (Cecropiaceae) in experimental models

  2017cites this paper
• Fucoxanthin Inhibits the Inflammation Response in Paw Edema Model through Suppressing MAPKs, Akt, and NFκB

  2016cites this paper
• Antipyretic and antiinflammatory properties of methanolic extracts of kigelia africana (Lam.) benth and acacia hockii de wild in animal models

  2016cites this paper
• Anti-Inflammatory Activity of Methanolic Leaf Extract of Kigelia Africana (Lam.) Benth and Stem Bark Extract of Acacia Hockii De Wild in Mice

  2016cites this paper
• Anti-inflammatory effects of Juncus effusus extract (JEE) on LPS-stimulated RAW 264.7 cells and edema models

  2016cites this paper
• Gamma-Terpinene Modulates Acute Inflammatory Response in Mice

  2015cites this paper
• Evaluation of the Anti-Inflammatory, Antioxidant and Immunomodulatory Effects of the Organic Extract of the Red Sea Marine Sponge Xestospongia testudinaria against Carrageenan Induced Rat Paw Inflammation

  2015cites this paper
• Anti-Inflammatory and Analgesic Effects of the Marine-Derived Compound Excavatolide B Isolated from the Culture-Type Formosan Gorgonian Briareum excavatum

  2015cites this paper
• Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease.

  2015cites this paper
• Pinosylvin and monomethylpinosylvin, constituents of an extract from the knot of Pinus sylvestris, reduce inflammatory gene expression and inflammatory responses in vivo.

  2015cites this paper
• Hederagenin, a major component of Clematis mandshurica Ruprecht root, attenuates inflammatory responses in RAW 264.7 cells and in mice.

  2015cites this paper
• In vitro effects of extracellular hypercapnic acidification on the reactivity of rat aorta: Rat aorta vasodilation during hypercapnic acidification.

  2015cites this paper
• Synthesis, toxicity study and anti-inflammatory effect of MHTP, a new tetrahydroisoquinoline alkaloid

  2015cites this paper
• Biomolecular evidence of anti-inflammatory effects by Clematis mandshurica Ruprecht root extract in rodent cells.

  2014cites this paper
• Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism.

  2014cites this paper
• Millettia pachycarpa exhibits anti-inflammatory activity through the suppression of LPS-induced NO/iNOS expression.

  2014cites this paper
• Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema.

  2014cites this paper
• U-Bang-Haequi Tang: A Herbal Prescription that Prevents Acute Inflammation through Inhibition of NF-κB-Mediated Inducible Nitric Oxide Synthase

  2014cites this paper
• Analgesic and anti-inflammatory effects of the methanol root extracts of some selected Nigerian medicinal plants

  2014cites this paper
• Carrageenan: a natural seaweed polysaccharide and its applications.

  2014cites this paper
• Anti-inflammatory activity of a methanol extract from Ardisia tinctoria on mouse macrophages and paw edema.

  2014cites this paper
• Inhibitory effect of Nymphaea pubescens Willd. flower extract on carrageenan-induced inflammation and CCl₄-induced hepatotoxicity in rats.

  2013cites this paper
• A modelagem molecular da proteína pha-like de Acacia Farnesiana revela mecanismo anti-inflamatório

  2013cites this paper
• O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation.

  2013cites this paper
• Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF-κB-Associated Nitric Oxide and Prostaglandin E2 production

  2013cites this paper
• Anti-Inflammatory Activities of Methanol Extract of Mastixia arborea C.B. Clarke as to Mouse Macrophage and Paw Edema

  2013cites this paper
• Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1

  2013cites this paper
• Inhibitory Effects of Traditional Herbal Formula Pyungwi-San on Inflammatory Response In Vitro and In Vivo

  2013cites this paper
• Anti-inflammatory effects of zingiber officinale roscoe involve suppression of nitric oxide and prostaglandin E2 production

  2013cites this paper
• The Antioxidant Effects of Isorhamnetin Contribute to Inhibit COX-2 Expression in Response to Inflammation: A Potential Role of HO-1

  2013cites this paper
• Inhibition of Acute Phase Inflammation by Laminaria japonica through Regulation of iNOS-NF-κB Pathway

  2013cites this paper
• Methanol Extract of Artemisia apiacea Hance Attenuates the Expression of Inflammatory Mediators via NF-κB Inactivation

  2013cites this paper
• Chemical characterization and in vivo anti-inflammatory activities of Actinidia callosa var. ephippioides via suppression of proinflammatory cytokines.

  2013cites this paper
• Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.

  2013cites this paper
• In vitro and in vivo anti-inflammatory effects of 4-methoxy-5- hydroxycanthin-6-one, a natural alkaloid from Picrasma quassioides.

  2013cites this paper
• Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis.

  2012cites this paper
• Bojesodok-eum, a Herbal Prescription, Ameliorates Acute Inflammation in Association with the Inhibition of NF-κB-Mediated Nitric Oxide and ProInflammatory Cytokine Production

  2012cites this paper
• A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline

  2012cites this paper
• Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo

  2012cites this paper
• Anti-Inflammatory Effects of Bangpungtongsung-San, a Traditional Herbal Prescription

  2012cites this paper
• Immunomodulatory effects of Zingiber officinale Roscoe var. rubrum (Halia Bara) on inflammatory responses relevant to psoriasis

  2012cites this paper
• A PRELIMINARY STUDY ON THE EFFECTS OF PETROLEUM ETHER & ALCOHOLIC BARK EXTRACT OF Anthocephalus cadamba (Roxb.) MIQ. IN ACUTE AND CHRONIC IN-VIVO INFLAMMATORY RAT MODELS

  2012cites this paper
• Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root.

  2012cites this paper
• Synthesis, acute toxicity and anti-inflammatory effect of bornyl salicylate, a salicylic acid derivative

  2012cites this paper
• Nicotinic acid induces antinociceptive and anti-inflammatory effects in different experimental models.

  2012cites this paper
• Inhibition of Nitric Oxide Synthase Gene Expression: In vivo Imaging Approaches of Nitric Oxide with Multimodal Imaging

  2012cites this paper
• Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors.

  2012cites this paper
• Flavonoids Eupatorin and Sinensetin Present in Orthosiphon stamineus Leaves Inhibit Inflammatory Gene Expression and STAT1 Activation

  2012cites this paper
• Anti-Inflammatory Activities of Inotilone from Phellinus linteus through the Inhibition of MMP-9, NF-κB, and MAPK Activation In Vitro and In Vivo

  2012cites this paper
• Peripheral Control of Inflammatory but Not Neuropathic Pain by Endogenous Cholinergic System

  2011cites this paper
• Anti-inflammatory and Antinociceptive Activity of Ouabain in Mice

  2011cites this paper
• Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models.

  2011cites this paper
• Anti-inflammatory and anti-nociceptive effect of Betula platyphylla var. japonica in human interleukin-1β-stimulated fibroblast-like synoviocytes and in experimental animal models.

  2011cites this paper
• Modulation of the nitric oxide metabolism overcomes the unresponsiveness of the diabetic human myocardium to protection against ischemic injury.

  2011cites this paper
• Evaluation of Antiinflammatory Activity of Centratherum anthelminticum (L) Kuntze Seed

  2010cites this paper
• Thioctic acid protects against carrageenan‐induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX‐2 mRNA and enhancement of IL‐10 mRNA

  2010cites this paper
• Protein kinase C in the Regulation of Inflammatory Genes iNOS and TTP

  2010cites this paper
• The Role of Neuronal Nitric Oxide Synthase (nNOS) in Ischaemia/Reoxygenation-induced injury and in protection of the Mammalian Myocardium

  2010cites this paper
• Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain

  2010cites this paper
• CHARACTERISTICS OF THE ANTIVASOCONSTRICTOR EFFECT OF PINACIDIL ON ISOLATED RADIAL ARTERY

  2010cites this paper
• Anti‐inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn.

  2010cites this paper
• α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations

  2010cites this paper
• Dual role of nNOS in ischemic injury and preconditioning

  2010cites this paper
• Effects of histidine and N-acetylcysteine on diclofenac-induced anti-inflammatory response in acute inflammation in rats.

  2010cites this paper
• Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto.

  2009cites this paper
• Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury‐induced neuropathic pain in rats

  2009cites this paper
• RESEARCH PAPER Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats

  2009cites this paper
• Inhibitory Effect of Amygdalin on Lipopolysaccharide-Inducible TNF-α and IL-1 β mRNA Expression and Carrageenan-Induced Rat Arthritis

  2008cites this paper
• Inducible nitric oxide mediates systemic microvascular leak following acid aspiration and mechanical ventilation

  2008cites this paper
• Anti‐inflammatory effects of liquiritigenin as a consequence of the inhibition of NF‐κB‐dependent iNOS and proinflammatory cytokines production

  2008influential citation