Cell and molecular biology of the multifunctional peptide, adrenomedullin.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  International Review of Cytology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0074-7696(02)21010-4PMID 12455746
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• High levels of circulating adrenomedullin in severe illness: correlation with C-reactive protein and evidence against the adrenal medulla as site of origin.

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• Adrenomedullin functions as an important tumor survival factor in human carcinogenesis

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• Adrenomedullin as a pancreatic hormone

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• Adrenomedullin in mammalian and human skin glands including the mammary gland.

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• Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat.

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• Adrenomedullin, an Endogenous Peptide, Counteracts Cardiovascular Damage

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• Functional Expression of Heteromeric Calcitonin Gene-related Peptide and Adrenomedullin Receptors in Yeast*

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• Effect of Adrenomedullin on Placental Arteries in Normal and Preeclamptic Pregnancies

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• Adrenomedullin, a new peptide, in patients with insulinoma.

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• Hypoxic induction of adrenomedullin in cultured human umbilical vein endothelial cells

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• [Multifunctional peptide, adrenomedullin].

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• Urinary adrenomedullin is related to ET-1 and salt intake in patients with mild essential hypertension. Salt Sensitivity Group of Italian Society of Hypertension.

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• Effect of adrenomedullin on the production of endothelin-1 and on its vasoconstrictor action in resistance arteries: evidence for a receptor-specific functional interaction in patients with heart failure

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• Stimulation of endogenous nitric oxide production is involved in the inhibitory effect of adrenomedullin on aldosterone secretion in the rat.

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• Distribution of preproadrenomedullin mRNA in the rat central nervous system and its modulation by physiological stressors

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• Plasma Adrenomedullin Levels in Asthmatic Patients

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• Expression of the adrenomedullin binding protein, complement factor H, in the pancreas and its physiological impact on insulin secretion.

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• Adrenomedullin and proadrenomedullin N-terminal 20 peptide induce histamine release from rat peritoneal mast cell.

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• Effects of TCV-116 on expression of NOS and adrenomedullin in failing heart of Dahl salt-sensitive rats.

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• Cardiac fibroblasts are major production and target cells of adrenomedullin in the heart in vitro.

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• Adrenomedullin Inhibits the Contraction of Cultured Rat Testicular Peritubular Myoid Cells Induced by Endothelin-11

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• Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations.

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• Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene.

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• The Relationship Between Plasma Concentration of Mature Adrenomedullin and Jugular Venous Oxygen Saturation During and After Cardiopulmonary Bypass

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• The role of the CGRP-receptor component protein (RCP) in adrenomedullin receptor signal transduction.

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• Increased endothelin‐1 and decreased adrenomedullin gene expression in the stenotic tissue of congenital pelvi‐ureteric junction obstruction in children

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• Distribution and molecular forms of adrenomedullin and proadrenomedullin N-terminal 20 peptide in the porcine gastrointestinal tract

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• Molecular forms of plasma and urinary adrenomedullin in normal, essential hypertension and chronic renal failure

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• Autoradiographic distribution of adrenomedullin receptors in the rat brain.

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• Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome

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• Adrenomedullin Suppresses fMLP-Induced Upregulation of CD11b of Human Neutrophils

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• A potential role for adrenomedullin as a local regulator of bone growth.

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• Adrenomedullin Inhibits Angiotensin II-Induced Expression of Tissue Factor and Plasminogen Activator Inhibitor-1 in Cultured Rat Aortic Endothelial Cells

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• Autocrine role of adrenomedullin in the human adrenal cortex.

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• Increased plasma adrenomedullin in patients undergoing percutaneous transluminal coronary angioplasty.

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• Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage.

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• Systemic administration of adrenomedullin(27-52) increases bone volume and strength in male mice.

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• Vascular Abnormalities and Elevated Blood Pressure in Mice Lacking Adrenomedullin Gene

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• Hypotensive and Natriuretic Actions of Adrenomedullin in Subjects With Chronic Renal Impairment

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• Adrenomedullin Induces Endothelium-Dependent Vasorelaxation via the Phosphatidylinositol 3-Kinase/Akt-Dependent Pathway in Rat Aorta

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• Elevation of two molecular forms of adrenomedullin in plasma and urine in patients with acute myocardial infarction treated with early coronary angioplasty.

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• Expression of adrenomedullin and peptide amidation activity in human prostate cancer and in human prostate cancer cell lines.

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• Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells.

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• Change of adrenomedullin concentrations in plasma and amniotic fluid, and human placental adrenomedullin expression with advancing gestation.

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• Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist.

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• Effect of adrenomedullin receptor and calcitonin gene-related peptide receptor antagonists on centrally mediated adrenomedullin renal action.

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• Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth

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• Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells.

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• Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells

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• Effect of adrenomedullin on the production of endothelin-1 and on its vasoconstrictor action in resistance arteries: evidence for a receptor-specific functional interaction in patients with heart failure.

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• Endothelin-1–Independent and Angiotensin II–Independent Induction of Adrenomedullin Gene Expression

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• The active molecular form of plasma adrenomedullin is extracted in the pulmonary circulation in patients with mitral stenosis: possible role of adrenomedullin in pulmonary hypertension.

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• Adrenomedullin is increased in the fetoplacental circulation in intrauterine growth restriction with abnormal umbilical artery waveforms.

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• Production and clearance sites of two molecular forms of adrenomedullin in human plasma.

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• Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats.

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• Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension

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• Increased Plasma Levels of Adrenomedullin in Patients with Hemodialysis

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• Desensitization and resensitization of adrenomedullin-sensitive receptor in rat mesangial cells.

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• Correlation of Plasma Adrenomedullin to Myocardial Preservation During Open-Heart Surgery

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• Expression of the adrenomedullin gene in epithelial ovarian cancer.

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• Immunoreactive adrenomedullin (AM) concentration in maternal plasma during human pregnancy and AM expression in placenta.

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• Adrenomedullin: potential in physiology and pathophysiology.

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• Human Adrenomedullin Gene Delivery Protects against Cardiac Hypertrophy, Fibrosis, and Renal Damage in Hypertensive Dahl Salt-Sensitive Rats

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• Changes in plasma adrenomedullin levels during the menstrual cycle.

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• Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism.

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• Tissue hypoxygenation activates the adrenomedullin system in vivo.

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• Effect of adrenomedullin infusion on basal and stimulated aldosterone secretion in conscious sheep with cervical adrenal autotransplants.

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• Adrenomedullin selectively inhibits angiotensin II‐induced aldosterone secretion in humans

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• Prognostic value of mid-regional proadrenomedullin in critically ill patients.

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• The Mammalian Peptide Adrenomedullin Acts as a Growth Factor in Tobacco Plants

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• Plasma adrenomedullin levels and nasopharyngeal carcinoma prognosis.

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• Involvement of adrenomedullin in spinal glial activation following chronic administration of morphine in rats

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