The ISG56/IFIT1 Gene Family

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Interferon and Cytokine Research

• Publication date

  2011-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/jir.2010.0101PMID 20950130PMCID PMC3021354
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Viral apoptosis is induced by IRF‐3‐mediated activation of Bax

  2010cited by this paper
• The interaction between interferon-induced protein with tetratricopeptide repeats-1 and eukaryotic elongation factor-1A

  2010cited by this paper
• Pattern recognition receptors and inflammation.

  2010cited by this paper
• High-Throughput Screening for TLR3–IFN Regulatory Factor 3 Signaling Pathway Modulators Identifies Several Antipsychotic Drugs as TLR Inhibitors

  2010cited by this paper
• IRF-9/STAT2 [corrected] functional interaction drives retinoic acid-induced gene G expression independently of STAT1.

  2009cited by this paper
• ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

  2009cited by this paper
• Structure and function of HCV IRES domains

  2009cited by this paper
• Protein structure prediction on the Web: a case study using the Phyre server

  2009cited by this paper
• Inducible Deposition of the Histone Variant H3.3 in Interferon-stimulated Genes*

  2009cited by this paper
• Novel Characteristics of the Function and Induction of Murine p56 Family Proteins

  2008cited by this paper
• STING an Endoplasmic Reticulum Adaptor that Facilitates Innate Immune Signaling

  2008cited by this paper
• IFN-Induced Protein with Tetratricopeptide Repeats 2 Inhibits Migration Activity and Increases Survival of Oral Squamous Cell Carcinoma

  2008cited by this paper
• The IRF family transcription factors in immunity and oncogenesis.

  2008cited by this paper
• Interferon‐inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

  2008cited by this paper
• The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.

  2008cited by this paper
• Tissue-Specific and Inducer-Specific Differential Induction of ISG56 and ISG54 in Mice

  2007cited by this paper
• Host Transcription Profiles upon Primary Respiratory Syncytial Virus Infection

  2007cited by this paper
• Structural Characterization of the Human Eukaryotic Initiation Factor 3 Protein Complex by Mass Spectrometry*S

  2007cited by this paper
• Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms

  2007cited by this paper
• RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins

  2006cited by this paper
• Reovirus Induces and Benefits from an Integrated Cellular Stress Response

  2006cited by this paper
• eIF3: a versatile scaffold for translation initiation complexes.

  2006cited by this paper
• Coordinated Regulation and Widespread Cellular Expression of Interferon-Stimulated Genes (ISG) ISG-49, ISG-54, and ISG-56 in the Central Nervous System after Infection with Distinct Viruses

  2006cited by this paper
• The GRIP1:IRF3 interaction as a target for glucocorticoid receptor‐mediated immunosuppression

  2006cited by this paper
• Identification of Japanese encephalitis virus-inducible genes in mouse brain and characterization of GARG39/IFIT2 as a microtubule-associated protein.

  2006cited by this paper
• Distinct Induction Patterns and Functions of Two Closely Related Interferon-inducible Human Genes, ISG54 and ISG56*

  2006cited by this paper
• Mouse p56 Blocks a Distinct Function of Eukaryotic Initiation Factor 3 in Translation Initiation*

  2005cited by this paper
• Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54.

  2005cited by this paper
• Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

  2005cited by this paper
• Analysis of Genes Induced by Sendai Virus Infection of Mutant Cell Lines Reveals Essential Roles of Interferon Regulatory Factor 3, NF-κB, and Interferon but Not Toll-Like Receptor 3

  2005cited by this paper
• Identification of Specific Cellular Genes Up-Regulated Late in Adenovirus Type 12 Infection

  2005cited by this paper
• Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

  2005cited by this paper
• Novel functions of proteins encoded by viral stress-inducible genes.

  2004cited by this paper
• Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

  2004cited by this paper
• Global and Distinct Targets of IRF-5 and IRF-7 during Innate Response to Viral Infection*

  2004cited by this paper
• Viral Stress-inducible Protein p56 Inhibits Translation by Blocking the Interaction of eIF3 with the Ternary Complex eIF2·GTP·Met-tRNAi*

  2003cited by this paper
• TPR proteins: the versatile helix.

  2003influential reference
• Alpha Interferon Induces Distinct Translational Control Programs To Suppress Hepatitis C Virus RNA Replication

  2003cited by this paper
• Transcriptional Profiling of Interferon Regulatory Factor 3 Target Genes: Direct Involvement in the Regulation of Interferon-Stimulated Genes

  2002cited by this paper
• A new pathway of translational regulation mediated by eukaryotic initiation factor 3

  2000cited by this paper
• Activation of cellular interferon-responsive genes after infection of human cells with herpes simplex virus type 1.

  2000cited by this paper
• Characterization of the Interaction between the Interferon-Induced Protein P56 and the Int6 Protein Encoded by a Locus of Insertion of the Mouse Mammary Tumor Virus

  2000cited by this paper
• Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

  1998cited by this paper
• IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes.

  1998cited by this paper
• Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays.

  1998cited by this paper
• Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.

  1997cited by this paper
• Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes.

  1997cited by this paper
• A novel interferon-inducible gene expressed during myeloid differentiation.

  1997cited by this paper
• The glucocorticoid attenuated response genes GARG-16, GARG-39, and GARG-49/IRG2 encode inducible proteins containing multiple tetratricopeptide repeat domains.

  1996cited by this paper
• MOLMOL: a program for display and analysis of macromolecular structures.

  1996cited by this paper
• Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3 (*)

  1995cited by this paper
• Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family.

  1994cited by this paper
• Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

  1994cited by this paper
• Molecular cloning and characterization of a murine LPS-inducible cDNA.

  1994cited by this paper
• The IFI‐56K and IFI‐54K interferon‐inducible human genes belong to the same gene family

  1988cited by this paper
• Transcriptional analyses of interferon-inducible mRNAs

  1987cited by this paper
• Regulation of synthesis and turnover of an interferon-inducible mRNA

  1986cited by this paper
• Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.

  1986cited by this paper
• Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons.

  1986cited by this paper
• Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA.

  1983cited by this paper
• Identification and Characterization of Interferon-Induced Proteins That Inhibit Alphavirus Replication (cid:1)

  year unknowncited by this paper

• Toxoplasma gondii GRA3 activates interferon-stimulated genes and STAT6 by the cGAS-STING pathway to promote parasite proliferation.

  2026cites this paper
• Identification of Fish Interferon-Stimulated Genes and Their Antiviral Mechanisms

  2026cites this paper
• Genetic resilience or resistance in poultry against avian influenza virus: mirage or reality?

  2025influential citation
• Interferon-Stimulated Genes: Novel Targets in Renal Pathogenesis

  2025cites this paper
• Short 5’ UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex

  2025cites this paper
• IFIT3 promotes lymph node metastasis by interacting with LASP1 to activate FAK-ERK signaling in esophageal squamous cell carcinoma

  2025cites this paper
• Dimethyl fumarate reprograms cervical cancer cells to enhance antitumor immunity by activating mtDNA-cGAS-STING pathway

  2025cites this paper
• Therapeutic potential of IFIT2 in human diseases.

  2025cites this paper
• Duck plague virus UL13 hijacks an RNA-binding protein, interferon induced protein with tetratricopeptide repeats 5, to promote replication.

  2025cites this paper
• The IFIT2–IFIT3 antiviral complex targets short 5’ untranslated regions on viral mRNAs for translation inhibition

  2025cites this paper
• FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition

  2025cites this paper
• Interferon signaling pathways in health and disease

  2025cites this paper
• In vitro characterization of the antiviral activity of Bat Interferon-Induced protein with tetratricopeptide repeats 5 (bat IFIT5) against bat-associated rabies virus

  2025cites this paper
• Evaluation of Genes and Molecular Pathways Common between Diffuse Large B-cell Lymphoma (DLBCL) and Systemic Lupus Erythematosus (SLE): A Systems Biology Approach

  2024cites this paper
• Molecular characterisation and expression analysis of an interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) homologue from Asian seabass (Lates calcarifer)

  2024cites this paper
• Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression.

  2024cites this paper
• Interferon‐stimulated gene 56 positively regulates Toll‐like receptor 3‐mediated CXCL10 expression in human renal proximal tubular epithelial cells

  2024influential citation
• Chemical immune conization of precancerous cervical lesions awakens immune cells and restores normal HPV negative and abnormal proliferation

  2024cites this paper
• Innate immune response against vector-borne bunyavirus infection and viral countermeasures

  2024cites this paper
• Influenza Virus Host Restriction Factors: The ISGs and Non-ISGs

  2024cites this paper
• Goose IFIT5 positively regulates goose astrovirus replication in GEF cells

  2024cites this paper
• An MST-based assay reveals new binding preferences of IFIT1 for canonically and noncanonically capped RNAs

  2024cites this paper
• Hapten-Mediated Chemical Immune Therapy with Drug Administration into Cervical Cancer without Hysterectomy:Awakening Immune Cells for Immunotherapy

  2024cites this paper
• The molecular language of RNA 5′ ends: guardians of RNA identity and immunity

  2024influential citation
• Dual Role of Extracellular Vesicles as Orchestrators of Emerging and Reemerging Virus Infections

  2024cites this paper
• Diversity and structural‐functional insights of alpha‐solenoid proteins

  2024cites this paper
• Cytosolic DNA sensors activation of human astrocytes inhibits herpes simplex virus through IRF1 induction

  2024cites this paper
• Antiviral Effects of Avian Interferon-Stimulated Genes

  2024cites this paper
• Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses

  2023cites this paper
• IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer

  2023cites this paper
• Roles of interferon induced protein with tetratricopeptide repeats (IFIT) family in autoimmune disease.

  2023cites this paper
• Type I interferons and Mycobacterium tuberculosis whole cell lysate induce distinct transcriptional responses in M. tuberculosis infection.

  2023cites this paper
• High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response

  2023cites this paper
• Mechanism of Immune Evasion in Mosquito-Borne Diseases

  2023cites this paper
• The diagnostic/prognostic roles and biological function of the IFIT family members in acute myeloid leukemia

  2023cites this paper
• Identification of functional pathways and potential genes associated with interferon signaling during human adenovirus type 7 infection by weighted gene coexpression network analysis

  2023influential citation
• Screening core genes and signaling pathways after SFTSV infection by integrated transcriptome profiling analysis

  2023cites this paper
• TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-β signaling pathway.

  2023cites this paper
• How Different Pathologies Are Affected by IFIT Expression

  2023cites this paper
• EGF Receptor-dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis.

  2023cites this paper
• Accessory fimbrial subunits and PPAD are necessary for TLR2 activation by Porphyromonas gingivalis.

  2023cites this paper
• Targeting Ligand Independent Tropism of siRNA‐LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells

  2023cites this paper
• African Swine Fever Virus encoded protein MGF360-13L inhibits cGAS-STING-mediated IFN-I Signaling Pathway.

  2023cites this paper
• Mining the potential therapeutic targets for COVID‐19 infection in patients with severe burn injuries via bioinformatics analysis

  2023cites this paper
• Proteomic and Phosphoproteomic Analysis Reveals Differential Immune Response to Hirame Novirhabdovirus (HIRRV) Infection in the Flounder (Paralichthys olivaceus) under Different Temperature

  2023cites this paper
• Analysis of m7G methylation modification patterns and pulmonary vascular immune microenvironment in pulmonary arterial hypertension

  2022cites this paper
• Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes

  2022cites this paper
• IFIT3 mediated the type I interferon antiviral response by targeting Senecavirus A entry, assembly and release pathways.

  2022cites this paper
• STAT1/IFIT2 signaling pathway is involved in PD-L1-mediated epithelial-to-mesenchymal transition in human esophageal cancer

  2022cites this paper
• Stochastic dynamics of Type-I interferon responses

  2022cites this paper
• Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells

  2022cites this paper
• Diminished antiviral innate immune gene expression in the placenta following a maternal SARS-CoV-2 infection

  2022cites this paper
• Overexpression of IFIT1 protects against LPS-induced acute lung injury via regulating CCL5-p65NF-κB signaling.

  2022cites this paper
• circ_0086296 induced atherosclerotic lesions via the IFIT1/STAT1 feedback loop by sponging miR-576-3p

  2022cites this paper
• Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

  2022cites this paper
• The Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2

  2022influential citation
• Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray

  2022cites this paper
• COL8A1 Promotes NSCLC Progression Through IFIT1/IFIT3-Mediated EGFR Activation

  2022cites this paper
• Identifying the functional pathways and potential genes associated with interferon signaling during human adenovirus type 7 (HAdV-7) by weighted gene co-expression network analysis

  2022cites this paper
• The Efficient Antiviral Response of A549 Cells Is Enhanced When Mitochondrial Respiration Is Promoted

  2022influential citation
• Downregulation of LRP/LR with siRNA inhibits several cancer hallmarks in lung cancer cells

  2022cites this paper
• The parapoxvirus Orf virus ORF116 gene encodes an antagonist of the interferon response.

  2021cites this paper
• Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy

  2021cites this paper
• RIG-I and MDA5 Protect Mice From Pichinde Virus Infection by Controlling Viral Replication and Regulating Immune Responses to the Infection

  2021cites this paper
• Identification of key molecular markers of acute coronary syndrome using peripheral blood transcriptome sequencing analysis and mRNA-lncRNA co-expression network construction

  2021cites this paper
• RETRACTED ARTICLE: IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling

  2021cites this paper
• Intracellular innate immunity and mechanism of action of cytosolic nucleic acid receptor‐mediated type I IFN against viruses

  2021cites this paper
• COVID-19 Biomarkers Detection Using 'KnowSeq' R Package

  2021cites this paper
• IFI44L as a Forward Regulator Enhancing Host Antituberculosis Responses

  2021cites this paper
• Gene Expression Pattern of Peyer’s Patch Lymphocytes Exposed to Kagocel Suggests Pattern-Recognition Receptors Mediate Its Action

  2021cites this paper
• Murine Ifit3 restricts the replication of Rabies virus both in vitro and in vivo.

  2021cites this paper
• IFIT5 Negatively Regulates the Type I IFN Pathway by Disrupting TBK1–IKKε–IRF3 Signalosome and Degrading IRF3 and IKKε

  2021cites this paper
• Molecular Characterization and Expression Analysis of SKIV Infection of Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1) in Epinephelus lanceolatus

  2021cites this paper
• An Analytical Review of the Structural Features of Pentatricopeptide Repeats: Strategic Amino Acids, Repeat Arrangements and Superhelical Architecture

  2021cites this paper
• Epigenomic and transcriptomic differences between low-grade and acute inflammation in LPS-induced murine immune cells

  2021cites this paper
• Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma.

  2021cites this paper
• Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes

  2021cites this paper
• Interfering With Inflammation: Heterogeneous Effects of Interferons in Graft-Versus-Host Disease of the Gastrointestinal Tract and Inflammatory Bowel Disease

  2021cites this paper
• Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

  2020cites this paper
• The Key Pathways and Born Genes of Bronchopulmonary Dysplasia

  2020cites this paper
• SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells

  2020cites this paper
• Proteome Analysis Reveals Syndecan 1 Regulates Porcine Sapelovirus Replication

  2020cites this paper
• Mechanistic modeling explains the dsRNA length-dependent activation of the RIG-I mediated immune response.

  2020cites this paper
• Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach

  2020cites this paper
• COVID-19 Myocarditis and Severity Factors： An Adult Cohort Study

  2020cites this paper
• ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells

  2020cites this paper
• IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist

  2020cites this paper
• Lipopolysaccharide Promotes Inflammatory Response via Enhancing IFIT1 Expression in Human Umbilical Vein Endothelial Cells

  2020cites this paper
• Adaptive evolution of interferon induced protein with tetratricopeptide repeats 5(IFIT5) in birds

  2020influential citation
• Inflammatory bowel disease pathobiology: the role of the interferon signature

  2020cites this paper
• Aus der Klinik mit Schwerpunkt Nephrologie und Intensivmedizin der Medizinischen Fakultät Charité – Universitätsmedizin Berlin DISSERTATION Use of interferon-stimulated gene expression level in renal transplant patients’ blood as biomarkers for diagnosis of rejection zur Erlangung des akademische

  2020cites this paper
• IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells

  2019cites this paper
• Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

  2019cites this paper
• Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses

  2019cites this paper
• Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses

  2019cites this paper
• OTT_A_220698 8139..8149

  2019cites this paper
• Long Noncoding RNA Lnc-MxA Inhibits Beta Interferon Transcription by Forming RNA-DNA Triplexes at Its Promoter

  2019cites this paper
• Emerging Functions of Human IFIT Proteins in Cancer

  2019cites this paper
• Regional Gene Repression by DNA Double-Strand Breaks in G1 Phase Cells

  2019cites this paper
• Attenuation of macrophage IL-10 responses by HIV-1

  2019cites this paper