Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Infectious Diseases

• Publication date

  2003-03-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/368163PMID 12660947
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Global epidemiology of infectious diseases

  2004cited by this paper
• Comparison of Alteration of Cell Surface Carbohydrates of the Chinchilla Tubotympanum and Colonial Opacity Phenotype of Streptococcus pneumoniae during Experimental Pneumococcal Otitis Media with or without an Antecedent Influenza A Virus Infection

  2002cited by this paper
• Current strategies for management of influenza in the elderly population.

  2002cited by this paper
• Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor.

  2002cited by this paper
• Oral oseltamivir treatment of influenza in children

  2001cited by this paper
• A mouse model of dual infection with influenza virus and Streptococcus pneumoniae

  2001cited by this paper
• Visualizing Pneumococcal Infections in the Lungs of Live Mice Using Bioluminescent Streptococcus pneumoniaeTransformed with a Novel Gram-Positive luxTransposon

  2001cited by this paper
• Effects of a large-scale intervention with influenza and 23-valent pneumococcal vaccines in adults aged 65 years or older: a prospective study.

  2001cited by this paper
• Pneumococcal Virulence Factors: Structure and Function

  2001cited by this paper
• Comparison of structural changes of cell surface carbohydrates in the eustachian tube epithelium of chinchillas infected with a Streptococcus pneumoniae neuraminidase-deficient mutant or its isogenic parent strain.

  2001cited by this paper
• Influenza vaccine effectiveness in preventing hospitalizations and deaths in persons 65 years or older in Minnesota, New York, and Oregon: data from 3 health plans.

  2001cited by this paper
• Molecular pathogenesis of pneumococcal pneumonia.

  2001cited by this paper
• Balanced Hemagglutinin and Neuraminidase Activities Are Critical for Efficient Replication of Influenza A Virus

  2000cited by this paper
• The impact of influenza epidemics on hospitalizations.

  2000cited by this paper
• Additive Attenuation of Virulence ofStreptococcus pneumoniae by Mutation of the Genes Encoding Pneumolysin and Other Putative Pneumococcal Virulence Proteins

  2000cited by this paper
• Evaluation of the Virulence of aStreptococcus pneumoniae Neuraminidase-Deficient Mutant in Nasopharyngeal Colonization and Development of Otitis Media in the Chinchilla Model

  2000cited by this paper
• Interdependence of Hemagglutinin Glycosylation and Neuraminidase as Regulators of Influenza Virus Growth: a Study by Reverse Genetics

  2000cited by this paper
• Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute Influenza

  2000cited by this paper
• Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group.

  2000cited by this paper
• Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment.

  1999cited by this paper
• Effects of influenza A virus on lectin-binding patterns in murine nasopharyngeal mucosa and on bacterial colonization

  1999cited by this paper
• Effect of lacto-N-neotetraose, asialoganglioside-GM1 and neuraminidase on adherence of otitis media-associated serotypes of Streptococcus pneumoniae to chinchilla tracheal epithelium.

  1999cited by this paper
• Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment.

  1999cited by this paper
• The global impact of influenza on morbidity and mortality.

  1999cited by this paper
• Respiratory viral infection predisposing for bacterial disease: a concise review.

  1999cited by this paper
• Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza.

  1999cited by this paper
• Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection

  1998cited by this paper
• Postreassortment changes in influenza A virus hemagglutinin restoring HA-NA functional match.

  1998cited by this paper
• Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections

  1997cited by this paper
• Options for the control of influenza III. Cairns, North Queensland, Australia (4-9 May 1996).

  1997cited by this paper
• Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group.

  1997cited by this paper
• A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs.

  1996cited by this paper
• Neutrophil deactivation by influenza A virus. Role of hemagglutinin binding to specific sialic acid-bearing cellular proteins.

  1995cited by this paper
• Apoptosis: a mechanism of cell killing by influenza A and B viruses

  1994cited by this paper
• Cellular and molecular mechanisms of bacterial adhesion to respiratory mucosa.

  1993cited by this paper
• Changes in the structure of the cell surface carbohydrates of the chinchilla tubotympanum following Streptococcus pneumoniae-induced otitis media.

  1992cited by this paper
• Pulmonary antibacterial defenses during mild and severe influenza virus infection

  1990cited by this paper
• Adherence of type I Streptococcus pneumoniae to tracheal epithelium of mice infected with influenza A/PR8 virus.

  1986cited by this paper
• Experimental Alteration of Chinchilla Middle Ear Mucosae by Bacterial Neuraminidase

  1986cited by this paper
• Comparison of infection rats and severity of illness for influenza A subtypes H1N1 and H3N2.

  1985cited by this paper
• Different virulence of influenza A virus strains and susceptibility to pneumococcal otitis media in chinchillas

  1983cited by this paper
• Mortality and influenza.

  1982cited by this paper
• Influenza A virus-induced polymorphonuclear leukocyte dysfunction in the pathogenesis of experimental pneumococcal otitis media

  1982cited by this paper
• Differing virulence of H1N1 and H3N2 influenza strains.

  1980cited by this paper
• Bacteriology and histopathology of the respiratory tract and lungs in fatal Asian influenza.

  1958cited by this paper

• Type I Interferon Targets Alveolar Macrophages to Promote Bacterial Pneumonia after Viral Infection.

  2025cites this paper
• Revisiting cattle respiratory health: key roles of the gut-lung axis in the dynamics of respiratory tract pathobiome

  2025cites this paper
• Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice

  2025cites this paper
• Effects of Modified Xuanbai Chengqi Decoction Against Secondary Streptococcus pneumoniae Infection Following Influenza Virus Infection: A Multi-Omics Analysis.

  2025cites this paper
• Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice

  2025cites this paper
• Role of Nedd4L in Macrophage Pro-Inflammatory Polarization Induced by Influenza A Virus and Lipopolysaccharide Stimulation

  2024cites this paper
• Biological puzzles solved by using Streptococcus pneumoniae: a historical review of the pneumococcal studies that have impacted medicine and shaped molecular bacteriology

  2024cites this paper
• Respiratory tract barrier dysfunction in viral-bacterial co-infection cases

  2024cites this paper
• Pathogenic Characteristics of an Infection with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus Alone or in Combination in Mice

  2024cites this paper
• Streptococcus pneumoniae epidemiology, pathogenesis and control

  2024cites this paper
• Developing a Coccidioides posadasii and SARS-CoV-2 Co-infection Model in the K18-hACE2 Transgenic Mouse

  2024cites this paper
• Immune predisposition drives susceptibility to pneumococcal pneumonia after mild influenza A virus infection in mice

  2023cites this paper
• The role of serum circulating microbial toxins in severity and cytokine storm of COVID positive patients

  2023cites this paper
• Pyrrolo[2,3-e]indazole as a novel chemotype for both influenza A virus and pneumococcal neuraminidase inhibitors

  2023cites this paper
• Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid–binding strategies

  2023cites this paper
• Galectin-1 mediates interactions between polymorphonuclear leukocytes and vascular endothelial cells, and promotes their extravasation during lipopolysaccharide-induced acute lung injury.

  2023cites this paper
• Community-Acquired Bacterial Co-infections and COVID-19.

  2023cites this paper
• Influenza A–induced cystic fibrosis transmembrane conductance regulator dysfunction increases susceptibility to Streptococcus pneumoniae

  2023cites this paper
• Innate Immune Response-Mediated Inflammation in Viral Pneumonia

  2023cites this paper
• A cooperativity between virus and bacteria during respiratory infections

  2023cites this paper
• Memory Th17 cell-mediated protection against lethal secondary pneumococcal pneumonia following influenza infection

  2023cites this paper
• Genomic Comparative Analysis of Two Multi-Drug Resistance (MDR) Acinetobacter baumannii Clinical Strains Assigned to International Clonal Lineage II Recovered Pre- and Post-COVID-19 Pandemic

  2023cites this paper
• Mathematical Modeling of the Lethal Synergism of Coinfecting Pathogens in Respiratory Viral Infections: A Review

  2023cites this paper
• A multiomics analysis of direct interkingdom dynamics between influenza A virus and Streptococcus pneumoniae uncovers host-independent changes to bacterial virulence fitness

  2022cites this paper
• Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infection during SARS-CoV-2 Infection

  2022cites this paper
• The role of serum circulating microbial toxins in severity and cytokine storm of COVID positive patients

  2022cites this paper
• The role of serum circulating microbial toxins in severity and cytokine storm of COVID positive patients

  2022cites this paper
• Novel Requirement for Staphylococcal Cell Wall-Anchored Protein SasD in Pulmonary Infection

  2022cites this paper
• Probiotics as a biotherapeutics for the management and prevention of respiratory tract diseases

  2022cites this paper
• The Contribution of Viral Proteins to the Synergy of Influenza and Bacterial Co-Infection

  2022cites this paper
• Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infections During SARS-CoV-2

  2022cites this paper
• Comparative outcomes of combined corticosteroid and remdesivir therapy with corticosteroid monotherapy in ventilated COVID-19 patients

  2022cites this paper
• Infection with different human influenza A subtypes affects the period of susceptibility to secondary bacterial infections in ferrets

  2022cites this paper
• The role of serum circulating microbial toxins in severity and cytokine storm of COVID positive patients

  2022cites this paper
• Cangma Huadu granules attenuate H1N1 virus-induced severe lung injury correlated with repressed apoptosis and altered gut microbiome

  2022cites this paper
• A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness.

  2022cites this paper
• Secondary streptococcal infection following influenza

  2022cites this paper
• The study of neuraminidase immunity in protection against secondary bacterial pneumonia induced by S. aureus after influenza infection in mice

  2021cites this paper
• The Spanish flu pandemic in 1918 in Russia. Questions a hundred years later

  2021cites this paper
• Infection metallomics for critical care in the post-COVID era.

  2021cites this paper
• Viral and Bacterial Co-Infections in the Lungs: Dangerous Liaisons

  2021cites this paper
• Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model

  2021cites this paper
• Host-informed therapies for the treatment of pneumococcal pneumonia.

  2021cites this paper
• Microbiota composition in the lower respiratory tract is associated with severity in patients with acute respiratory distress by influenza

  2021cites this paper
• Co-infections as Modulators of Disease Outcome: Minor Players or Major Players?

  2021cites this paper
• Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection.

  2021cites this paper
• Liu Shen Wan inhibits influenza virus-induced secondary Staphylococcus aureus infection in vivo and in vitro.

  2021cites this paper
• Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections With Streptococcus pneumoniae

  2021cites this paper
• Изучение роли иммунитета к нейраминидазе вируса гриппа в защите от вторичной бактериальной пневмонии, индуцированной S. aureus после гриппозной инфекции у мышей

  2021cites this paper
• A Murine Model for Enhancement of Streptococcus pneumoniae Pathogenicity upon Viral Infection and Advanced Age

  2021cites this paper
• Пандемия испанки 1918 года в России. Вопросы сто лет спустя

  2021cites this paper
• Altered Signal Transduction in the Immune Response to Influenza Virus and S. pneumoniae or S. aureus Co-Infections

  2021cites this paper
• Interactions of Bacteriophages and Bacteria at the Airway Mucosa: New Insights Into the Pathophysiology of Asthma

  2021cites this paper
• Causes and Consequences of COVID-19-Associated Bacterial Infections

  2021cites this paper
• From virus to inflammation, how influenza promotes lung damage

  2020cites this paper
• Bacterial co‐infections with SARS‐CoV‐2

  2020cites this paper
• Association of Influenza Activity and Environmental Conditions With the Risk of Invasive Pneumococcal Disease

  2020cites this paper
• Secondary Bacterial Infections in Patients With Viral Pneumonia

  2020cites this paper
• Bacterial Pneumonia

  2020cites this paper
• A Murine Model for the Transition of Streptococcus pneumoniae from Asymptomatic Colonizer to Systemic Pathogen

  2020cites this paper
• What came first, the virus or the egg: Innate immunity during viral coinfections

  2020cites this paper
• GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection

  2020cites this paper
• PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection

  2020cites this paper
• Clinical Analysis of Atelectasis Caused by Influenza A in Xiamen Children’s Hospital Between 2017 and 2019

  2020cites this paper
• Staphylococcus aureus Lipase 1 Enhances Influenza A Virus Replication

  2020cites this paper
• Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

  2020cites this paper
• Influenza and pregnancy

  2020cites this paper
• Impact of Influenza on Pneumococcal Vaccine Effectiveness during Streptococcus pneumoniae Infection in Aged Murine Lung

  2020cites this paper
• Respiratory Virus Co-infection in Acute Respiratory Infections in Children

  2020cites this paper
• Can animal models really teach us anything about pneumonia? Pro

  2020cites this paper
• Pediatric Pulmonology

  2020cites this paper
• Co-infection of SARS-COV-2 and Influenza A Virus: A Case Series and Fast Review

  2020cites this paper
• Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways

  2020cites this paper
• Infections that cause secondary immune deficiency

  2020cites this paper
• Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis

  2020cites this paper
• Influenza Neuraminidase: A Neglected Protein and Its Potential for a Better Influenza Vaccine

  2020cites this paper
• [Surveillance, prevention, and control of influenza virus in Peru].

  2019cites this paper
• Diminished immune responses with aging predispose older adults to common and uncommon influenza complications.

  2019cites this paper
• Combined immunization with attenuated live influenza vaccine and chimeric pneumococcal recombinant protein improves the outcome of virus-bacterial infection in mice

  2019cites this paper
• [Influenza infection: An update for clinicians].

  2019cites this paper
• Mucosal vaccine based on attenuated influenza virus and the group B Streptococcus recombinant peptides protected mice from influenza and S. pneumoniae infections

  2019cites this paper
• Invasive Pneumococcal and Meningococcal Disease.

  2019cites this paper
• Pneumopathies bactériennes secondaires aux infections respiratoires virales : de l’étude expérimentale in vitro à l’analyse descriptive des données hospitalières en passant par l’étude prospective d’une cohorte de patients

  2019cites this paper
• Use of metagenomic sequencing as a tool for pathogen discovery with further investigation of novel reptilian serpentoviruses, The

  2019cites this paper
• Herpesvirus-bacteria synergistic interaction in periodontitis.

  2019cites this paper
• Streptococcus pneumoniae: Invasion and Inflammation

  2019cites this paper
• The Potential of Influenza HA-Specific Immunity in Mitigating Lethality of Postinfluenza Pneumococcal Infections

  2019cites this paper
• Dynamic Pneumococcal Genetic Adaptations Support Bacterial Growth and Inflammation during Coinfection with Influenza

  2019cites this paper
• Volatile scents of influenza A and S. pyogenes (co-)infected cells

  2019cites this paper
• Back to the Future: Lessons Learned From the 1918 Influenza Pandemic

  2018cites this paper
• Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies.

  2018cites this paper
• Clinical Differences in Hospitalized Adult Influenza Patients between the A (H1N1) pdm09 and the A (H3N2) Seasons in Japan

  2018cites this paper
• The Streptococcus pyogenes fibronectin/tenascin-binding protein PrtF.2 contributes to virulence in an influenza superinfection

  2018cites this paper
• Nasopharyngeal colonization from Streptococcus pneumoniae serotypes in Uruguayan children before and after pneumococcal conjugate vaccines

  2018cites this paper
• The effect of P38 MAP kinase inhibition in a mouse model of influenza

  2018cites this paper
• Caractérisation et impact du microbiote bactérien respiratoire sur les maladies virales

  2018cites this paper
• The emerging influenza virus threat: status and new prospects for its therapy and control

  2018cites this paper
• Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

  2018cites this paper
• Effective prevention of secondary pneumococcal infection following influenza virus infection.

  2018cites this paper
• Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

  2018cites this paper