STING contributes to anti-glioma immunity via triggering type-I IFN signals in the tumor microenvironment

T. Ohkuri,A. Ghosh,A. Kosaka,Jianzhong Zhu,M. Ikeura,M. David,Simon C Watkins,Saumendra N. Sarkar,H. Okada

Published 2014 in Journal of Immunotherapy for Cancer

ABSTRACT

Meeting abstracts While type-I interferons (IFNs) play critical roles in antiviral and antitumor activity, it remains to be elucidated how type-I IFNs are produced in sterile conditions of the tumor microenvironment and directly impacts tumor-infiltrating immune cells. We report that both human and

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