Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Blood

• Publication date

  1991-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD.V78.5.1373.BLOODJOURNAL7851373PMID 1652311
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells.

  1991cited by this paper
• Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression.

  1991cited by this paper
• The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells.

  1990cited by this paper
• Cytomegalovirus infection after autologous bone marrow transplantation: occurrence of cytomegalovirus disease and effect on engraftment.

  1990cited by this paper
• Reconstruction of the haemopoietic and immune systems after marrow transplantation.

  1990cited by this paper
• Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial.

  1989cited by this paper
• Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

  1989cited by this paper
• Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts.

  1989cited by this paper
• T-cell ontogeny after autologous bone marrow transplantation: failure to synthesize interleukin-2 (IL-2) and lack of CD2- and CD3-mediated proliferation by both CD4- and CD8+ cells even in the presence of exogeneous IL-2.

  1989cited by this paper
• Lymphokine production by T-cell clones after human bone marrow transplantation.

  1989cited by this paper
• Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation.

  1988cited by this paper
• Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host

  1988cited by this paper
• Ganciclovir/immunoglobulin combination therapy for the treatment of human cytomegalovirus-associated interstitial pneumonia in bone marrow allograft recipients.

  1988cited by this paper
• Requirements for T cell recognition and elimination of retrovirally-transformed cells.

  1988cited by this paper
• A nonstructural viral protein expressed by a recombinant vaccinia virus protects against lethal cytomegalovirus infection

  1988cited by this paper
• Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation.

  1988cited by this paper
• Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants.

  1988cited by this paper
• Generation of human cytomegalovirus-specific cytotoxic T-lymphocytes in a short-term culture.

  1988cited by this paper
• Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin.

  1988cited by this paper
• Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses

  1988cited by this paper
• Human cytomegalovirus‐specific cytotoxic T cells: their precursor frequency and stage specificity

  1988cited by this paper
• CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

  1987cited by this paper
• Interstitial pneumonitis after bone marrow transplantation. Assessment of risk factors.

  1986cited by this paper
• Risk factors for cytomegalovirus infection after human marrow transplantation.

  1986cited by this paper
• Recent clinical isolates of cytomegalovirus suppress human cytomegalovirus-specific human leukocyte antigen-restricted cytotoxic T-lymphocyte activity

  1986cited by this paper
• Requirement for HLA-DR+ accessory cells in natural killing of cytomegalovirus-infected fibroblasts

  1986cited by this paper
• Long-lasting deficit of functional T cell precursors in human bone marrow transplant recipients revealed by limiting dilution methods.

  1986cited by this paper
• Cytomegalovirus - its cellular immunology and biology.

  1986cited by this paper
• Immune recovery following allogeneic bone marrow transplantation.

  1985cited by this paper
• Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs

  1985cited by this paper
• Cellular interactions in marrow-grafted patients. III. Normal interleukin 1 and defective interleukin 2 production in short-term patients and in those with chronic graft-versus-host disease.

  1985cited by this paper
• RECOVERY OF IN VIVO CELLULAR IMMUNITY AFTER HUMAN MARROW GRAFTING: Influence of Time Postgrafting and Acute Graft‐Versus‐Host Disease

  1984cited by this paper
• Cellular interactions in marrow-grafted patients. I. Impairment of cell-mediated lympholysis associated with graft-vs-host disease and the effect of interleukin 2.

  1983cited by this paper
• Allogeneic Bone‐Marrow Transplantation

  1983cited by this paper
• Human cytomegalovirus‐specific cytotoxic T lymphocytes: requirements for in vitro generation and specificity

  1983cited by this paper
• Human bone marrow allograft recipients: production of, and responsiveness to, interleukin 2.

  1983cited by this paper
• Monomorphic anti-HLA-A,B,C monoclonal antibodies detecting molecular subunits and combinatorial determinants.

  1982cited by this paper
• Cytotoxic t cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients.

  1982cited by this paper
• HLA-restricted cytotoxic T lymphocyte and nonthymic cytotoxic lymphocyte responses to cytomegalovirus infection of bone marrow transplant recipients.

  1981cited by this paper
• Cytomegalovirus infection and specific cell-mediated immunity after marrow transplant.

  1980cited by this paper
• Bone marrow transplantation.

  1977cited by this paper
• Blastogenic response of human lymphocytes to human cytomegalovirus.

  1977cited by this paper
• Bone-marrow transplantation (first of two parts).

  1975cited by this paper

• Risk Factors for Invasive Mould Infections in Adult Patients with Hematological Malignancies and/or Stem Cell Transplant: a Systematic Literature Review and Meta-analysis.

  2025cites this paper
• Persistent Low-Level Variants in a Subset of Viral Genes Are Highly Predictive of Poor Outcome in Immunocompromised Patients With Cytomegalovirus Infection

  2024cites this paper
• Different Antigen-Specific CD4+ and CD8+ T-Cell Response against HCMV Proteins in Pregnant Women with Primary Infection and in Control Subjects with Remote Infection

  2024cites this paper
• QuantiFERON monitor predicts early cytomegalovirus infection and viral burden in allogeneic hematopoietic stem cell transplantation

  2024cites this paper
• Cytomegalovirus infection is associated with thymic dysfunction and chronic graft-versus-host disease after pediatric hematopoietic stem cell transplantation.

  2024cites this paper
• Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

  2024cites this paper
• CMV reactivation during pretransplantation evaluation: a novel risk factor for posttransplantation CMV reactivation

  2024cites this paper
• Mucosal T-cell responses to chronic viral infections: Implications for vaccine design

  2024cites this paper
• Direct Antigen Presentation is the Canonical Pathway of Cytomegalovirus CD8 T-cell Priming Regulated by Balanced Immune Evasion Mounting a Strong Antiviral Response

  2023cites this paper
• Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

  2023cites this paper
• Cancer Therapy With TCR-Engineered T Cells: Current Strategies, Challenges, and Prospects

  2022cites this paper
• Dominant epitopes presented by prevalent HLA alleles permit wide use of banked CMVpp65 T cells in adoptive therapy

  2022cites this paper
• Common T-Cell-Receptor Motifs and Features in Patients with Cytomegalovirus (CMV)-Seronegative End-Stage Renal Disease Receiving a Peptide Vaccination against CMV

  2022cites this paper
• Cytomegalovirus and other herpesviruses after hematopoietic cell and solid organ transplantation: From antiviral drugs to virus-specific T cells.

  2022cites this paper
• Dominant Antiviral CD8+ T Cell Responses Empower Prophylactic Antibody-Eliciting Vaccines Against Cytomegalovirus

  2022cites this paper
• Dynamics of Inflammatory and Neurodegenerative Biomarkers after Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

  2022cites this paper
• Prevention and management of human cytomegalovirus in pediatric HSCT recipients: A review

  2022cites this paper
• Real-World Outcomes Associated With Letermovir Use for Cytomegalovirus Primary Prophylaxis in Allogeneic Hematopoietic Cell Transplant Recipients: A Systematic Review and Meta-analysis of Observational Studies

  2022cites this paper
• Human cytomegalovirus infection: A considerable issue following allogeneic hematopoietic stem cell transplantation

  2021influential citation
• Cytomegalovirus Prophylaxis versus Pre-emptive Strategy: Different CD4+ and CD8+ T Cell Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation.

  2021cites this paper
• Peptide Vaccination against Cytomegalovirus Induces Specific T Cell Response in Responses in CMV Seronegative End-Stage Renal Disease Patients

  2021cites this paper
• Pathogenesis of human cytomegalovirus in the immunocompromised host

  2021cites this paper
• Profiling Human Cytomegalovirus-Specific T Cell Responses Reveals Novel Immunogenic Open Reading Frames

  2021cites this paper
• Recent Approaches and Strategies in the Generation of Anti-human Cytomegalovirus Vaccines.

  2021cites this paper
• NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir

  2021cites this paper
• Utility of CMV-Specific Immune Monitoring for the Management of CMV in Solid Organ Transplant Recipients: A Clinical Update

  2021cites this paper
• Circulatory follicular helper T lymphocytes associate with lower incidence of CMV infection in kidney transplant recipients

  2021cites this paper
• Human Cytomegalovirus and Epstein-Barr virus specific immunity in patients with ulcerative colitis

  2021cites this paper
• Letermovir prophylaxis in T-cell–depleted transplants: breakthrough and rebound infections in the postmarketing setting

  2021cites this paper
• Viral opportunistic infections in Mauritian cynomolgus macaques undergoing allogeneic stem cell transplantation mirror human transplant infectious disease complications

  2020cites this paper
• Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay.

  2020cites this paper
• Make Sure You Have a Safety Net: Updates in the Prevention and Management of Infectious Complications in Stem Cell Transplant Recipients

  2020cites this paper
• Cytomegalovirus in Hematopoietic Stem Cell Transplant Recipients: Prevention, Diagnosis, and Treatment

  2020cites this paper
• How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation.

  2020cites this paper
• How I Treat MAJOR COMPLICATIONS AFTER ALLOGENEIC STEM CELL TRANSPLANTATION How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation

  2020cites this paper
• Cell therapy for cytomegalovirus infection

  2020cites this paper
• Donor CMV-specific cytotoxic T lymphocytes successfully treated drug-resistant cytomegalovirus encephalitis after allogeneic hematopoietic stem cell transplantation

  2020cites this paper
• Cellular Therapeutic Approaches to Cytomegalovirus Infection Following Allogeneic Stem Cell Transplantation

  2020cites this paper
• Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1

  2020cites this paper
• Successful treatment of CMV, EBV, and adenovirus tissue infection following HLA‐mismatched allogeneic stem cell transplant using infusion of third‐party T cells from multiple donors in addition to antivirals, rituximab, and surgery

  2020cites this paper
• Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation.

  2019cites this paper
• Principles and Applications of Cellular Therapy in the Setting of Hematopoietic Cell Transplant

  2019cites this paper
• Cytomegalovirus memory inflation and immune protection

  2019cites this paper
• Mechanisms of AIDS-related cytomegalovirus retinitis

  2019cites this paper
• CMV-Reactive NK Cells in Pediatric Post-Hematopoietic Stem Cell Transplant.

  2019cites this paper
• Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation—a phase I/II study

  2019cites this paper
• Modulation of innate and adaptive immunity by cytomegaloviruses

  2019cites this paper
• Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European Conference on Infections in Leukaemia (ECIL 7).

  2019cites this paper
• A novel simplified method of generating cytomegalovirus-specific cytokine-induced killer cells of high specificity and superior potency with GMP compliance.

  2019cites this paper
• Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models

  2019cites this paper
• Cytomegalovirus infection in a T-cell lymphoma patient presenting with multiple gastrointestinal ulcers: a case report

  2019cites this paper
• Expansion of CD8 hCD57+ T cells after allogeneic BMT is related with a low incidence of relapse and with cytomegalovirus infection

  2019cites this paper
• Human cytomegalovirus (HCMV) infection/re-infection: development of a protective HCMV vaccine.

  2019cites this paper
• Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients

  2019cites this paper
• Immunological and Clinical Impact of Manipulated and Unmanipulated DLI after Allogeneic Stem Cell Transplantation of AML Patients

  2019cites this paper
• CMV seronegative donors: Effect on clinical severity of CMV infection and reconstitution of CMV-specific immunity.

  2018cites this paper
• Rapid reconstitution of CMV‐specific T‐cells after stem‐cell transplantation

  2018cites this paper
• TCR clonality of CNIV-specific CTL after BMT

  2018cites this paper
• Management of Infections in the Immunocompromised Host

  2018cites this paper
• Human cytomegalovirus vaccine development: Immune responses to look into vaccine strategy

  2018cites this paper
• Prevention and treatment of cytomegalovirus in immunocompromised patients: beyond DNA polymerase inhibition.

  2018cites this paper
• The Detailed Kinetics of Cytomegalovirus-specific T cell Responses after Hematopoietic Stem Cell Transplantation: 1 Year Follow-up Data

  2018cites this paper
• Cytomegalovirus Infection in Multi-Transfused -Thalassemia Major Patients in Basrah. Serology and Molecular Diagnosis

  2018cites this paper
• Construction of expression vectors of capsid proteins from goose parvovirus and investigation of the immunogenicity.

  2018cites this paper
• OPINION Prevention and treatment of cytomegalovirus in immunocompromised patients: beyond DNA polymerase inhibition

  2018cites this paper
• Maternal Immunity and the Natural History of Congenital Human Cytomegalovirus Infection

  2018cites this paper
• Infections in Hematopoietic Stem Cell Transplant Recipients

  2018cites this paper
• Cytotoxic T Cells for Infections: From Donor Specific to “Off the Shelf”

  2018cites this paper
• Impact of Cytomegalovirus Viral Load on Probability of Spontaneous Clearance and Response to Preemptive Therapy in Allogeneic Stem Cell Transplantation Recipients.

  2017cites this paper
• Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation.

  2017cites this paper
• Who Is the Patient at Risk of CMV Recurrence: A Review of the Current Scientific Evidence with a Focus on Hematopoietic Cell Transplantation

  2017cites this paper
• Diagnostic usefulness of dynamic changes of CMV-specific T-cell responses in predicting CMV infections in HCT recipients.

  2017cites this paper
• Identifying Cytomegalovirus Complications Using the Quantiferon-CMV Assay After Allogeneic Hematopoietic Stem Cell Transplantation

  2017cites this paper
• Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses

  2017cites this paper
• Viral Infections in Organ Transplant Recipients

  2017cites this paper
• Cytomegalovirus Treatment in Pediatric Hematopoietic Stem Cell Transplant Patients

  2017cites this paper
• Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function

  2017cites this paper
• Changes in the Immune System at Different Stages of Life

  2017cites this paper
• A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells.

  2017cites this paper
• Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations

  2017cites this paper
• Anti-CMV CD8+ T-cell epitope specificities and T-cell receptor repertoires in African study subjects

  2017cites this paper
• Reconstitution of CMV-specific T-cells following adoptive T-cell immunotherapy and haematopoietic stem cell transplantation

  2016cites this paper
• Poor CMV-specific CD8+ T central memory subset recovery at early stage post-HSCT associates with refractory and recurrent CMV reactivation.

  2016cites this paper
• Mutual Interference between Cytomegalovirus and Reconstitution of Protective Immunity after Hematopoietic Cell Transplantation

  2016cites this paper
• Refining human T-cell immunotherapy of cytomegalovirus disease: a mouse model with ‘humanized’ antigen presentation as a new preclinical study tool

  2016cites this paper
• Cytomegalovirus and immunotherapy: opportunistic pathogen, novel target for cancer and a promising vaccine vector.

  2016cites this paper
• Strategies to control human cytomegalovirus infection in adult hematopoietic stem cell transplant recipients.

  2016cites this paper
• The Neonatal CD8+ T Cell Repertoire Rapidly Diversifies during Persistent Viral Infection

  2016cites this paper
• Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance

  2016cites this paper
• Limited Effector Memory B-Cell Response to Envelope Glycoprotein B During Primary Human Cytomegalovirus Infection.

  2016cites this paper
• Adoptive T-cell Therapy for Viral Disease in the Setting of Hematopoietic Cell Transplantation

  2016cites this paper
• Human cytomegalovirus antiviral drug resistance in hematopoietic stem cell transplantation: current state of the art

  2016cites this paper
• Prospects of a vaccine for the prevention of congenital cytomegalovirus disease

  2016cites this paper
• Efficacy and Safety of a Preemptive Antiviral Therapy Strategy Based on Combined Virological and Immunological Monitoring for Active Cytomegalovirus Infection in Allogeneic Stem Cell Transplant Recipients

  2016cites this paper
• Cytomegalovirus Infection After Stem Cell Transplantation

  2016cites this paper
• Comparative magnitude and kinetics of human cytomegalovirus‐specific CD4+ and CD8+ T‐cell responses in pregnant women with primary versus remote infection and in transmitting versus non‐transmitting mothers: Its utility for dating primary infection in pregnancy

  2016cites this paper
• Heterogeneity of Specific CD4+ and CD8+ T Cells Stimulated by CMV pp65 and IE1 Antigens

  2016cites this paper
• Adoptive Immunotherapy for Infection Control Using Antigen-Specific Donor-Derived T Cells After Transplantation

  2016cites this paper
• Infección Activa por el Citomegalovirus (CMV) en el trasplante alogénico de precursores hematopoyéticos:Investigación de nuevos factores biológicos para la estimación del riesgo y análisis integral de los mecanismos inmunitarios que la previenen y controlan

  2016influential citation
• Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies.

  2015cites this paper