human embryonic stem cells: biology and clinical implications

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Expert Reviews in Molecular Medicine

• Publication date

  2005-09-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1017/S1462399405009804PMID 16171533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Directed differentiation of human embryonic stem cells into functional hepatic cells

  2007cited by this paper
• Human embryonic stem cells derived without feeder cells.

  2005cited by this paper
• Neurotrophin-Induced Differentiation of Human Embryonic Stem Cells on Three-Dimensional Polymeric Scaffolds

  2005cited by this paper
• Transcriptome Profiling of Human and Murine ESCs Identifies Divergent Paths Required to Maintain the Stem Cell State

  2005cited by this paper
• Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression

  2005cited by this paper
• Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential.

  2005cited by this paper
• A proteome analysis of conditioned media from human neonatal fibroblasts used in the maintenance of human embryonic stem cells

  2005cited by this paper
• Generation of Peripheral Sensory and Sympathetic Neurons and Neural Crest Cells from Human Embryonic Stem Cells

  2005cited by this paper
• Human‐Serum Matrix Supports Undifferentiated Growth of Human Embryonic Stem Cells

  2005cited by this paper
• The Stem Cell Pluripotency Factor NANOG Activates Transcription with Two Unusually Potent Subdomains at Its C Terminus*

  2005cited by this paper
• Activin A Maintains Pluripotency of Human Embryonic Stem Cells in the Absence of Feeder Layers

  2005cited by this paper
• Embryonic stem cells: prospects for developmental biology and cell therapy.

  2005cited by this paper
• Downregulation of NANOG Induces Differentiation of Human Embryonic Stem Cells to Extraembryonic Lineages

  2005cited by this paper
• Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

  2005cited by this paper
• RETRACTED: Contribution of the PI3K/Akt/PKB signal pathway to maintenance of self‐renewal in human embryonic stem cells

  2005cited by this paper
• Pluripotential competence of cells associated with Nanog activity.

  2005cited by this paper
• Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development.

  2005cited by this paper
• Bridging the BMP and Wnt Pathways by PI3 Kinase/Akt and 14-3-3?

  2005cited by this paper
• Human embryonic stem cells express an immunogenic nonhuman sialic acid

  2005cited by this paper
• Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers.

  2005cited by this paper
• In vitro and in vivo analyses of human embryonic stem cell‐derived dopamine neurons

  2005cited by this paper
• TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

  2005cited by this paper
• Derivation of Human Embryonic Stem Cell Lines in Serum Replacement Medium Using Postnatal Human Fibroblasts as Feeder Cells

  2005cited by this paper
• WNT signalling and haematopoiesis: a WNT–WNT situation

  2005cited by this paper
• Preserving the genetic integrity of human embryonic stem cells

  2005cited by this paper
• An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells

  2005cited by this paper
• Oct‐4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem Cells

  2004cited by this paper
• Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

  2004cited by this paper
• Dopaminergic Differentiation of Human Embryonic Stem Cells

  2004cited by this paper
• Available human feeder cells for the maintenance of human embryonic stem cells.

  2004cited by this paper
• Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells.

  2004cited by this paper
• Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties.

  2004cited by this paper
• Derivation of midbrain dopamine neurons from human embryonic stem cells.

  2004cited by this paper
• Feeder Layer- and Serum-Free Culture of Human Embryonic Stem Cells1

  2004cited by this paper
• Properties of Pluripotent Human Embryonic Stem Cells BG01 and BG02

  2004cited by this paper
• Differences between human and mouse embryonic stem cells.

  2004cited by this paper
• Spontaneous differentiation of germ cells from human embryonic stem cells in vitro.

  2004cited by this paper
• Morula-derived human embryonic stem cells.

  2004cited by this paper
• LIF/STAT3 Signaling Fails to Maintain Self‐Renewal of Human Embryonic Stem Cells

  2004cited by this paper
• Derivation, growth and applications of human embryonic stem cells.

  2004cited by this paper
• Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.

  2004cited by this paper
• Self-renewal of teratocarcinoma and embryonic stem cells

  2004cited by this paper
• Specific Knockdown of Oct4 and β2‐microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells

  2004cited by this paper
• Evidence of a Pluripotent Human Embryonic Stem Cell Line Derived from a Cloned Blastocyst

  2004cited by this paper
• Derivation of embryonic stem-cell lines from human blastocysts.

  2004cited by this paper
• Differentiation of Human and Mouse Embryonic Stem Cells along a Hepatocyte Lineage

  2004cited by this paper
• Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells.

  2004cited by this paper
• Immortalized Fibroblast‐Like Cells Derived from Human Embryonic Stem Cells Support Undifferentiated Cell Growth

  2004cited by this paper
• Derivation of Human Embryonic Stem Cells from Day‐8 Blastocysts Recovered after Three‐Step In Vitro Culture

  2004cited by this paper
• CD34+CD38- hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern.

  2004cited by this paper
• Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin

  2004cited by this paper
• The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE

  2004cited by this paper
• Controlled, Scalable Embryonic Stem Cell Differentiation Culture

  2004cited by this paper
• Expression of Nodal, Lefty-A, and Lefty-B in Undifferentiated Human Embryonic Stem Cells Requires Activation of Smad2/3*

  2004cited by this paper
• Electromechanical integration of cardiomyocytes derived from human embryonic stem cells

  2004cited by this paper
• Human Embryonic Stem Cells Possess Immune‐Privileged Properties

  2004cited by this paper
• Maintenance of Pluripotency in Human Embryonic Stem Cells Is STAT3 Independent

  2004cited by this paper
• Living donor liver transplantation and tolerance: a potential strategy in cholangiocarcinoma.

  2003cited by this paper
• Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells.

  2003cited by this paper
• Generation of Hepatocyte-Like Cells from Human Embryonic Stem Cells

  2003cited by this paper
• Molecular signature of human embryonic stem cells and its comparison with the mouse.

  2003cited by this paper
• BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3.

  2003cited by this paper
• The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

  2003cited by this paper
• Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei

  2003cited by this paper
• Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors

  2003cited by this paper
• Multipotent cell lineages in early mouse development depend on SOX2 function.

  2003cited by this paper
• Marker succession during the development of keratinocytes from cultured human embryonic stem cells

  2003cited by this paper
• A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells.

  2003cited by this paper
• Preimplantation genetic diagnosis as a novel source of embryos for stem cell research.

  2003cited by this paper
• In Vitro Osteogenic Differentiation of Human ES Cells

  2003cited by this paper
• Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells

  2003cited by this paper
• Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.

  2003cited by this paper
• Directed neuronal differentiation of human embryonic stem cells

  2003cited by this paper
• Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells

  2003cited by this paper
• Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.

  2002cited by this paper
• Signalling, cell cycle and pluripotency in embryonic stem cells.

  2002cited by this paper
• Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons

  2002cited by this paper
• Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells

  2002cited by this paper
• Derivation and spontaneous differentiation of human embryonic stem cells *

  2002cited by this paper
• Preimplantation Human Embryos and Embryonic Stem Cells Show Comparable Expression of Stage‐Specific Embryonic Antigens

  2002cited by this paper
• BMP4 initiates human embryonic stem cell differentiation to trophoblast

  2002cited by this paper
• Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy.

  2002cited by this paper
• HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.

  2002cited by this paper
• Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells

  2002cited by this paper
• Stem cell medicine encounters the immune system

  2002cited by this paper
• Cardiomyocyte differentiation of mouse and human embryonic stem cells *

  2002cited by this paper
• Characterization of the expression of MHC proteins in human embryonic stem cells

  2002cited by this paper
• Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

  2002cited by this paper
• Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells

  2002cited by this paper
• Manipulation of dendritic cells as an approach to improved outcomes in transplantation

  2002cited by this paper
• Neural progenitors from human embryonic stem cells

  2001cited by this paper
• Hematopoietic colony-forming cells derived from human embryonic stem cells

  2001cited by this paper
• Feeder-free growth of undifferentiated human embryonic stem cells

  2001cited by this paper
• Induced neuronal differentiation of human embryonic stem cells.

  2001cited by this paper
• Embryo-derived stem cells: of mice and men.

  2001cited by this paper
• In vitro differentiation of transplantable neural precursors from human embryonic stem cells

  2001cited by this paper
• Insulin production by human embryonic stem cells.

  2001cited by this paper
• Human embryonic stem cells.

  2001cited by this paper
• Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes.

  2001cited by this paper
• Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

  2000cited by this paper

• Wnt regulation of hematopoietic stem cell development and disease.

  2023cites this paper
• Stem Cell Differentiation into Cardiomyocytes: Current Methods and Emerging Approaches

  2022cites this paper
• Stem Cell Biology and the Cardiovascular System

  2019cites this paper
• Extracellular Matrix-mediated Lung Epithelial Cell Differentiation

  2016cites this paper
• Differentiation of Human Embryonic Stem Cells on Periodontal Ligament Fibroblasts.

  2016cites this paper
• Stem Cells in Neuroendocrinology

  2016cites this paper
• Pituitary Stem Cells: Quest for Hidden Functions

  2016cites this paper
• Microfabricated Devices for Adherent Stem Cell Culture

  2015influential citation
• Derivation and characterization of human embryonic stem cells on human amnion epithelial cells

  2015cites this paper
• InVitro Differentiation andMaturation of Human Embryonic StemCell intoMultipotent Cells

  2014cites this paper
• Pituitary cell differentiation from stem cells and other cells: toward restorative therapy for hypopituitarism?

  2014cites this paper
• Metabolic Regulation of Redox Status in Stem Cells

  2014cites this paper
• Differentiation of human embryonic stem cells into hepatocytes and their in vivo application for hepatitis C viral production

  2014cites this paper
• Comparison of hES-MP cell immunophenotype after expansion in fetal bovine serum or in platelet lysates, manufactured from expired platelet concentrate

  2013cites this paper
• Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

  2013cites this paper
• Expansion and Osteogenic Differentiation of Human Amniotic Fluid Derived Stem Cells

  2013cites this paper
• Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming.

  2012cites this paper
• Derivation of Stromal (Skeletal and Mesenchymal) Stem-Like Cells from Human Embryonic Stem Cells

  2012cites this paper
• A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells

  2012cites this paper
• Disease mechanisms in mitochondrial maintenance disorders

  2012cites this paper
• Controlling the Emergence of Hematopoietic Progenitor Cells from Pluripotent Stem Cells

  2012cites this paper
• An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells

  2011cites this paper
• Human Cord Blood-Derived Stem Cells in Transplantation and Regenerative Medicine

  2011cites this paper
• New tools for improving culture strategies for Hepatocyte differentiation

  2011cites this paper
• Therapeutic Potentials of Mesenchymal Stem Cells Derived from Human Umbilical Cord

  2011cites this paper
• Mouse embryonic stem cell-derived thymic epithelial cell progenitors enhance T-cell reconstitution after allogeneic bone marrow transplantation.

  2011cites this paper
• Stem Cell Therapy for Neuromuscular Diseases

  2011cites this paper
• Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species.

  2011cites this paper
• Rejuvenation of the Thymic Microenvironment by ESC-derived Thymic Epithelial Progenitors

  2011cites this paper
• In Vitro Differentiation and Maturation of Human Embryonic Stem Cell into Multipotent Cells

  2011cites this paper
• Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing

  2011cites this paper
• Optimisation of Human Embryonic Stem Cell Derivation and Culture - Towards Clinical Quality

  2010cites this paper
• Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells

  2010cites this paper
• Human embryonic stem cell differentiation on periodontal ligament fibroblasts.

  2010cites this paper
• Recent highlights on bone stem cells: a report from Bone Stem Cells 2009, and not only…

  2010cites this paper
• Whole body regeneration in a colonial ascidian, Botrylloides violaceus.

  2009cites this paper
• NBCS: a novel osteoconductive scaffold for new bone formation in animal spinal fusion models

  2009cites this paper
• Differentiation of human embryonic stem cells on periodontal ligament fibroblasts in vitro.

  2008cites this paper
• Endotoxin-induced silencing of mesoderm induction and functional differentiation: role of HMGB1 in pluripotency and infection.

  2008cites this paper
• Recent advancements towards the derivation of immune-compatible patient-specific human embryonic stem cell lines.

  2008cites this paper
• Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells

  2008cites this paper
• Downregulation of Multiple Stress Defense Mechanisms During Differentiation of Human Embryonic Stem Cells

  2008cites this paper
• Genetic modification and mesodermal differentiation of human embryonic stem cells

  2008cites this paper
• Genetic Modification and Mesodermal Differentiation of Human Embryonic Stem Cells

  2008cites this paper
• Developmental change in germline and stem cell lineages in ascidian life history evolution

  2008cites this paper
• Critical issues of clinical human embryonic stem cell therapy for brain repair.

  2008cites this paper
• Application of stem cells in bone repair

  2008cites this paper
• Human embryonic stem cells: origins, characteristics and potential for regenerative therapy

  2008influential citation
• Differences between human embryonic stem cell lines.

  2007cites this paper
• Epigenetic Reprogramming of Nonreplicating Somatic Cells for Long-Term Proliferation by Temporary Cell–Cell Contact

  2007cites this paper
• COMPONENT SCREENING FOR NOVEL XENO­FREE MEDIUM FOR HUMAN EMBRYONIC STEM CELLS

  2007cites this paper
• The low rate of HLA class I molecules on the human embryonic stem cell line HS293 is associated with the APM components' expression level

  2007cites this paper
• The use of Peritoneal Mesothelium as a Potential Source of Adult Stem Cells

  2007cites this paper
• Human Embryonic Stem Cells; A novel model system for early human development

  2006cites this paper
• Embryonic stem cell bank

  2006cites this paper
• The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

  2006cites this paper
• Identity tests: determination of cell line cross-contamination

  2006cites this paper
• Embryonic stem cell bank: a work proposal.

  2006cites this paper
• Defined culture conditions of human embryonic stem cells.

  2006cites this paper
• InTRoDUCTIon To MARKERS of STEM CEllS AnD THEIR nEURAl DERIVATES

  year unknowncites this paper