Maximizing Cellular Adaptation to Endurance Exercise in Skeletal Muscle.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Cell Metabolism

• Publication date

  2018-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.cmet.2018.04.014PMID 29719234
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adaptations to endurance training depend on exercise‐induced oxidative stress: exploiting redox interindividual variability

  2018cited by this paper
• Hypobaric live high‐train low does not improve aerobic performance more than live low‐train low in cross‐country skiers

  2018cited by this paper
• Biology of VO2max: looking under the physiology lamp

  2017cited by this paper
• A Practical and Time-Efficient High-Intensity Interval Training Program Modifies Cardio-Metabolic Risk Factors in Adults with Risk Factors for Type II Diabetes

  2017cited by this paper
• Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers

  2017cited by this paper
• No Superior Adaptations to Carbohydrate Periodization in Elite Endurance Athletes

  2017cited by this paper
• Periodized Nutrition for Athletes

  2017cited by this paper
• New horizons in hypoxia signaling pathways

  2017cited by this paper
• The Manipulation of Pace within Endurance Sport

  2017cited by this paper
• Exploiting Environmental Factors to Improve Health and Performance Passive heat acclimation improves skeletal muscle contractility in humans

  2017cited by this paper
• Heat and Dehydration Additively Enhance Cardiovascular Outcomes following Orthostatically-Stressful Calisthenics Exercise

  2017cited by this paper
• Regulation of erythropoiesis after normoxic return from chronic sustained and intermittent hypoxia.

  2017cited by this paper
• Sprinting Toward Fitness.

  2017cited by this paper
• Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans

  2017cited by this paper
• Heat stress induces mitochondrial adaptations in skeletal muscle

  2017cited by this paper
• Refuting the myth of non‐response to exercise training: ‘non‐responders’ do respond to higher dose of training

  2017cited by this paper
• Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli.

  2017cited by this paper
• β-Hydroxybutyrate: A Signaling Metabolite.

  2017cited by this paper
• Omics and Exercise: Global Approaches for Mapping Exercise Biological Networks.

  2017cited by this paper
• Does Short-Duration Heat Exposure at a Matched Cardiovascular Intensity Improve Intermittent-Running Performance in a Cool Environment?

  2017cited by this paper
• Heat shock protein 90 contributes to cutaneous vasodilation through activating nitric oxide synthase in young male adults exercising in the heat.

  2017cited by this paper
• The Training Characteristics of the World's Most Successful Female Cross-Country Skier

  2017cited by this paper
• Exercise-induced skeletal muscle signaling pathways and human athletic performance.

  2016cited by this paper
• Hyperthermia, dehydration, and osmotic stress: unconventional sources of exercise-induced reactive oxygen species.

  2016cited by this paper
• Performance success or failure is influenced by weeks lost to injury and illness in elite Australian track and field athletes: A 5-year prospective study.

  2016cited by this paper
• Heat stress and dehydration in adapting for performance: Good, bad, both, or neither?

  2016cited by this paper
• Training Load and Fatigue Marker Associations with Injury and Illness: A Systematic Review of Longitudinal Studies

  2016cited by this paper
• Passive heat therapy improves endothelial function, arterial stiffness and blood pressure in sedentary humans

  2016cited by this paper
• Passive heat therapy improves cutaneous microvascular function in sedentary humans via improved nitric oxide-dependent dilation.

  2016cited by this paper
• Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?

  2016cited by this paper
• Enhanced Endurance Performance by Periodization of Carbohydrate Intake: "Sleep Low" Strategy.

  2016cited by this paper
• Does ‘altitude training’ increase exercise performance in elite athletes?

  2016cited by this paper
• No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes

  2016cited by this paper
• CrossTalk opposing view: Heat acclimatization does not improve exercise performance in a cool condition

  2016cited by this paper
• Twenty‐eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle

  2016cited by this paper
• CrossTalk proposal: Heat acclimatization does improve performance in a cool condition

  2016cited by this paper
• Unravelling the mechanisms regulating muscle mitochondrial biogenesis.

  2016cited by this paper
• Heat therapy promotes the expression of angiogenic regulators in human skeletal muscle.

  2016cited by this paper
• Adaptations of skeletal muscle mitochondria to exercise training

  2016cited by this paper
• Heat stress acutely activates insulin-independent glucose transport and 5′-AMP-activated protein kinase prior to an increase in HSP72 protein in rat skeletal muscle

  2015cited by this paper
• Exercise Metabolism: Historical Perspective.

  2015cited by this paper
• Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude.

  2015cited by this paper
• The Kenyan runners

  2015cited by this paper
• Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training

  2015cited by this paper
• Adaptations and mechanisms of human heat acclimation: Applications for competitive athletes and sports

  2015cited by this paper
• Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise

  2015cited by this paper
• Performance Enhancement: What Are the Physiological Limits?

  2015cited by this paper
• Carbohydrate availability and exercise training adaptation: Too much of a good thing?

  2015cited by this paper
• Effects of sleeping with reduced carbohydrate availability on acute training responses.

  2015cited by this paper
• Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

  2015cited by this paper
• Ramping up the signal: promoting endurance training adaptation in skeletal muscle by nutritional manipulation

  2014cited by this paper
• Dynamic epigenetic responses to muscle contraction.

  2014cited by this paper
• Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle.

  2014cited by this paper
• Kidney-synthesized erythropoietin is the main source for the hypoxia-induced increase in plasma erythropoietin in adult humans

  2014cited by this paper
• Integrative biology of exercise.

  2014cited by this paper
• Human heat adaptation.

  2014cited by this paper
• Hypoxic training: effect on mitochondrial function and aerobic performance in hypoxia.

  2014cited by this paper
• Heat acclimation, epigenetics, and cytoprotection memory.

  2014cited by this paper
• Exercise metabolism and the molecular regulation of skeletal muscle adaptation.

  2013cited by this paper
• Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis.

  2013cited by this paper
• Lactate kinetics at the lactate threshold in trained and untrained men.

  2013cited by this paper
• Elevation of muscle temperature stimulates muscle glucose uptake in vivo and in vitro

  2013cited by this paper
• Hypovolemia explains the reduced stroke volume at altitude

  2013cited by this paper
• Improvements in exercise performance with high-intensity interval training coincide with an increase in skeletal muscle mitochondrial content and function.

  2013cited by this paper
• Nutritional strategies to modulate the adaptive response to endurance training.

  2013cited by this paper
• Contemporary nutrition approaches to optimize elite marathon performance.

  2013cited by this paper
• Heat stress activates the Akt/mTOR signalling pathway in rat skeletal muscle

  2013cited by this paper
• Drinking Behaviors of Elite Male Runners During Marathon Competition

  2012cited by this paper
• Impact of Environmental Parameters on Marathon Running Performance

  2012cited by this paper
• Acute exercise remodels promoter methylation in human skeletal muscle.

  2012cited by this paper
• Mild heat stress induces mitochondrial biogenesis in C2C12 myotubes.

  2012cited by this paper
• Brain and skin do not contribute to the systemic rise in erythropoietin during acute hypoxia in humans

  2012cited by this paper
• Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

  2012cited by this paper
• What makes champions? A review of the relative contribution of genes and training to sporting success

  2012cited by this paper
• Exercise with low glycogen increases PGC-1α gene expression in human skeletal muscle

  2012cited by this paper
• Human mRNA Response to Exercise and Temperature

  2011cited by this paper
• The upper limit of aerobic power in humans

  2011cited by this paper
• Heat acclimation and exercise training interact when combined in an overriding and trade-off manner: physiologic-genomic linkage.

  2011cited by this paper
• Nutritional modulation of training-induced skeletal muscle adaptations.

  2011cited by this paper
• Training with low muscle glycogen enhances fat metabolism in well-trained cyclists.

  2010cited by this paper
• Soleus adaptation to combined exercise and heat acclimation: physiogenomic aspects.

  2010cited by this paper
• Carbohydrate Availability and Training Adaptation: Effects on Cell Metabolism

  2010cited by this paper
• Molecular signals that shape the integrative responses of the heat-acclimated phenotype.

  2010cited by this paper
• Genomics and proteomics of heat acclimation.

  2010cited by this paper
• Total hemoglobin mass and blood volume of elite Kenyan runners.

  2010cited by this paper
• Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen

  2010cited by this paper
• AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

  2009cited by this paper
• Toward a Science of Exceptional Achievement

  2009cited by this paper
• The Glycogen-Binding Domain on the AMPK β Subunit Allows the Kinase to Act as a Glycogen Sensor

  2009cited by this paper
• The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.

  2009cited by this paper
• Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content.

  2009cited by this paper
• The response of human skeletal muscle tissue to hypoxia

  2009cited by this paper
• HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

  2008cited by this paper
• Skeletal muscle adaptation and performance responses to once a day versus twice every second day endurance training regimens.

  2008cited by this paper
• Thermal tolerance of contractile function in oxidative skeletal muscle: no protection by antioxidants and reduced tolerance with eicosanoid enzyme inhibition.

  2008cited by this paper
• Epidermal sensing of oxygen is essential for systemic hypoxic response.

  2008cited by this paper
• Does recombinant human Epo increase exercise capacity by means other than augmenting oxygen transport?

  2008cited by this paper
• Endurance exercise performance: the physiology of champions

  2008cited by this paper
• Effect of post-exercise sauna bathing on the endurance performance of competitive male runners.

  2007cited by this paper
• Increased temperature, not cardiac load, activates heat shock transcription factor 1 and heat shock protein 72 expression in the heart.

  2007cited by this paper

• The RTF-Compass: Navigating the Trade-Off Between Thermogenic Potential and Ferroptotic Stress in Adipocytes

  2026cites this paper
• Periodized carbohydrate intake influences metabolic flexibility and indices of running economy during endurance training in recreationally active males

  2026cites this paper
• Training Load Oscillation and Epigenetic Plasticity: Molecular Pathways Connecting Energy Metabolism and Athletic Personality

  2026cites this paper
• Endurance Training in Olympic Winter Sports: A Narrative Review of the Current Literature and Future Research Priorities

  2026cites this paper
• Transcriptomic analysis reveals the impact of concurrent, resistance, and endurance training on skeletal muscle

  2026cites this paper
• The Effect Salvia Hispanica L Seed Extract on Stres Oxidatif in Rats with Overtraining

  2025cites this paper
• Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α

  2025cites this paper
• Effects of Ashwagandha (Withania somnifera) Supplementation on Special Endurance and Response Time of Elite Wrestlers.

  2025cites this paper
• Exercise improves hypobaric hypoxia-induced skeletal muscle dysfunction via Sirt1-Mediated myotube and mitochondrial remodeling.

  2025cites this paper
• Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners

  2025cites this paper
• Molecular Mediators of the Cardiac Benefits of Exercise.

  2025cites this paper
• Phosphoproteomics Uncovers Exercise Intensity-Specific Skeletal Muscle Signaling Networks Underlying High-Intensity Interval Training in Healthy Male Participants

  2025cites this paper
• Nutritional Strategies to Improve Post-exercise Recovery and Subsequent Exercise Performance: A Narrative Review

  2025cites this paper
• The Impact of Breakfast Consumption or Omission on Exercise Performance and Adaptations: A Narrative Review

  2025cites this paper
• Respiratory frequency: from health to sports performance monitoring

  2025cites this paper
• Lactate, Capnia, and Fat Oxidation as Therapeutic Axes for SARS-CoV-2 Spike Protein-Induced Sequelae

  2025cites this paper
• Novel insights into diagnosis and management of hyperreactivity: a narrative review

  2025cites this paper
• Passive heating in sport: Context specific benefits, detriments, and considerations.

  2025cites this paper
• Acute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review

  2025cites this paper
• Adaptações fisiológicas em resposta ao treinamento físico em atletas de alto rendimento em modalidades de endurance

  2024cites this paper
• Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers

  2024cites this paper
• The Race Within a Race: Starting Together, Finishing Apart.

  2024cites this paper
• Responses to Exercise with Low Carbohydrate Availability on Muscle Glycogen and Cell Signaling: A Systematic Review and Meta-analysis

  2024cites this paper
• Engaging athletes as research participants. A document analysis of published sport science literature

  2024cites this paper
• Vgll2 as an integrative regulator of mitochondrial function and contractility specific to skeletal muscle

  2024cites this paper
• Exercise-induced response of proteinogenic and non-proteinogenic plasma free amino acids is sport-specific: A comparison of sprint and endurance athletes

  2024cites this paper
• Circulating miRNA Signaling for Fatty Acid Metabolism in Response to a Maximum Endurance Test in Elite Long-Distance Runners

  2024cites this paper
• Physical Therapy and the Arrhythmias: The potential benefits and challenges of their kinship

  2024cites this paper
• Eryngium carlinae Extract and Exercise Improve Blood Lipid Profile and Skeletal Muscle Function in Obese Rats

  2024cites this paper
• Phosphoproteomics uncovers exercise intensity-specific signaling networks underlying high-intensity interval training in human skeletal muscle

  2024cites this paper
• Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise

  2024cites this paper
• A refined rodent model of anorexia nervosa: Simulating state‐specific effects of caloric restriction and weight restoration

  2024cites this paper
• Resistance Training in the Heat: Mechanisms of Hypertrophy and Performance Enhancement.

  2024cites this paper
• Exercise-Regulated Mitochondrial and Nuclear Signalling Networks in Skeletal Muscle

  2024cites this paper
• Locally applied heat stress during exercise training may promote adaptations to mitochondrial enzyme activities in skeletal muscle

  2024cites this paper
• Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

  2024cites this paper
• A Five-Week Periodized Carbohydrate Diet Does Not Improve Maximal Lactate Steady-State Exercise Capacity and Substrate Oxidation in Well-Trained Cyclists compared to a High-Carbohydrate Diet

  2024cites this paper
• MYH1G-AS is a chromatin-associated lncRNA that regulates skeletal muscle development in chicken

  2024cites this paper
• Effect of Beetroot Juice Supplementation on Aerobic Capacity in Female Athletes: A Randomized Controlled Study

  2024cites this paper
• Exercise, nutrition, and medicine timing in metabolic health: implications for management of Type 2 Diabetes.

  2024cites this paper
• Study of Physiological Adaptations in Vertical Kilometer Runners: Focus on Cardiorespiratory and Local Muscle Demands

  2024cites this paper
• Effects of Heat and Humidity on Cycling Training and Performance: A Narrative Review

  2023cites this paper
• 8 weeks of 2S-hesperidin prevents a decrease in pO2 at submaximal intensity in amateur cyclists in off-season: randomized controlled trial.

  2023cites this paper
• Regulation of the endocannabinoid system by endurance and resistance exercise in hypoxia in human skeletal muscle.

  2023cites this paper
• Implications of Heat Stress-induced Metabolic Alterations for Endurance Training

  2023cites this paper
• Recovery in normobaric hypoxia as an additional stimulus for high-intensity intermittent training

  2023cites this paper
• Effects of Resveratrol on Muscle Inflammation, Energy Utilisation, and Exercise Performance in an Eccentric Contraction Exercise Mouse Model

  2023cites this paper
• Exercise induces tissue-specific adaptations to enhance cardiometabolic health.

  2023cites this paper
• The molecular athlete: exercise physiology from mechanisms to medals

  2023cites this paper
• Interaction of the C2C12 myotube contractions and glucose availability on transcriptome and extracellular vesicle microRNAs.

  2023cites this paper
• Effect of Acute Exercise on HIF-1⍺ and EPO Levels in Athletes Acclimatized to Low-Middle Altitude

  2023cites this paper
• Ocular Surface Allostasis—When Homeostasis Is Lost: Challenging Coping Potential, Stress Tolerance, and Resilience

  2023cites this paper
• Baf155 regulates skeletal muscle metabolism via HIF-1a signaling

  2023cites this paper
• Environmental heat stress offsets adaptation associated with carbohydrate periodization in trained male triathletes

  2023cites this paper
• Effects of high‐resistance wheel running on hallmarks of endurance and resistance training adaptations in mice

  2023influential citation
• Passive heat stress induces mitochondrial adaptations in skeletal muscle

  2023cites this paper
• Canonical and extra‐telomeric functions of telomerase: Implications for healthy ageing conferred by endurance training

  2023influential citation
• Temporal dynamics of the multi-omic response to endurance exercise training across tissues

  2023cites this paper
• Identification of global transcriptional variations in human PBMCs two months post heat injury helps categorization heat tolerant or heat intolerant phenotypes.

  2023cites this paper
• Modeling exercise using optogenetically contractible Drosophila larvae

  2022cites this paper
• The hepatokine TSK maintains myofiber integrity and exercise endurance and contributes to muscle regeneration

  2022cites this paper
• High intramuscular triglyceride turnover rates and the link to insulin sensitivity: Influence of obesity, type 2 diabetes and physical activity.

  2022cites this paper
• Infrared laser exposure in combination with branchedchain amino acid stimulates physiological adaptation of skeletal muscles

  2022cites this paper
• The first horse gut microbiome gene catalog reveals that rare microbiome ensures better cardiovascular fitness in endurance horses

  2022cites this paper
• Muscle endoplasmic reticulum stress in exercise

  2022cites this paper
• Relationships between Sex and Adaptation to Physical Exercise in Young Athletes: A Pilot Study

  2022cites this paper
• The First Horse Gut Microbiome Gene Catalog Reveals That Rare Microbiome Ensures Better Cardiovascular Fitness During Endurance Racing

  2022cites this paper
• Microfluidic Tissue Engineering and Bio‐Actuation

  2022cites this paper
• The Effect of Repetitive Whole Body Cryotherapy Treatment on Adaptations to a Strength and Endurance Training Programme in Physically Active Males

  2022cites this paper
• High Energetic Demand of Elite Rowing – Implications for Training and Nutrition

  2022cites this paper
• Unsupervised Clustering of Heartbeat Dynamics Allows for Real Time and Personalized Improvement in Cardiovascular Fitness

  2022cites this paper
• Exercise as an Aging Mimetic: A New Perspective on the Mechanisms Behind Exercise as Preventive Medicine Against Age-Related Chronic Disease

  2022cites this paper
• Piezo1 stimulates mitochondrial function via cAMP signaling

  2022cites this paper
• A Comparison Of Heat Treatment-induced Skeletal Muscle Adaptations Relative To Exercise Training

  2022cites this paper
• Whole body vibration, an alternative for exercise to improve recovery from surgery?

  2022cites this paper
• New Horizons in Carbohydrate Research and Application for Endurance Athletes

  2022cites this paper
• Role of TLR4 in endoplasmic reticulum stress induced by physical exercise in skeletal muscle

  2022cites this paper
• Mining the equine gut metagenome: poorly-characterized taxa associated with cardiovascular fitness in endurance athletes

  2022cites this paper
• Shared and unique phosphoproteomics responses in skeletal muscle from exercise models and in hyperammonemic myotubes

  2022cites this paper
• Factors Affecting Sea-Level Performance Following Altitude Training in Elite Athletes

  2022cites this paper
• Molecular Responses to Acute Exercise and Their Relevance for Adaptations in Skeletal Muscle to Exercise Training.

  2022cites this paper
• Social aspects and sports performance: the principle of social-corporeal individuality

  2022cites this paper
• Adding High-Intensity Interval Training to Classical Resistance Training Does Not Impede the Recovery from Inactivity-Induced Leg Muscle Weakness

  2022cites this paper
• Blackcurrants: A Nutrient-Rich Source for the Development of Functional Foods for Improved Athletic Performance

  2022cites this paper
• Estrogen-related Receptor Signaling in Skeletal Muscle Fitness

  2022cites this paper
• Effects of small-sided games on oxygen consumption, agility, and focused attention in football

  2021cites this paper
• Endurance Is Improved in Female Rats After Living High-Training High Despite Alterations in Skeletal Muscle

  2021cites this paper
• Lifelong Aerobic Exercise Alleviates Sarcopenia by Activating Autophagy and Inhibiting Protein Degradation via the AMPK/PGC-1α Signaling Pathway

  2021cites this paper
• Effects of short-term graded dietary carbohydrate intake on intramuscular and whole-body metabolism during moderate-intensity exercise.

  2021cites this paper
• Transcriptomic, proteomic and phosphoproteomic underpinnings of daily exercise performance and zeitgeber activity of training in mouse muscle

  2021cites this paper
• Muscle Ionic Shifts During Exercise: Implications for Fatigue and Exercise Performance.

  2021cites this paper
• RNA Sequencing of Whole Blood Defines the Signature of High Intensity Exercise at Altitude in Elite Speed Skaters

  2021cites this paper
• Effect of ginger extract ingestion on skeletal muscle glycogen contents and endurance exercise in male rats

  2021cites this paper
• Under the Hood: Skeletal Muscle Determinants of Endurance Performance

  2021cites this paper
• Nutritional approaches to counter performance constraints in high‐level sports competition

  2021cites this paper
• Performance effects of periodized carbohydrate restriction in endurance trained athletes – a systematic review and meta-analysis

  2021cites this paper
• Temperate performance and metabolic adaptations following endurance training performed under environmental heat stress

  2021influential citation
• Mitochondrial-derived peptides and exercise.

  2021cites this paper
• High-intensity exercise training — too much of a good thing?

  2021cites this paper
• HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review

  2021cites this paper