Konditionale Mutagenese in der Maus: Generierung und Analyse konditionaler Mausmutanten

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Unknown venue

• Publication date

  2005-12-20

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability

  2005cited by this paper
• Analysis of Marginal Zone B Cell Development in the Mouse with Limited B Cell Diversity: Role of the Antigen Receptor Signals in the Recruitment of B Cells to the Marginal Zone1

  2005cited by this paper
• c-fos overexpression in splenic B cells augments development of marginal zone B cells.

  2005influential reference
• New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

  2005cited by this paper
• Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells.

  2005cited by this paper
• Neuronal migration in the murine rostral migratory stream requires serum response factor

  2005cited by this paper
• Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection

  2004cited by this paper
• Ternary Complex Factor-Serum Response Factor Complex-Regulated Gene Activity Is Required for Cellular Proliferation and Inhibition of Apoptotic Cell Death

  2004cited by this paper
• Ets ternary complex transcription factors.

  2004influential reference
• Molecular interactions regulate BCR signal inhibition by CD22 and CD72.

  2004cited by this paper
• The Role of CXCR4 in Maintaining Peripheral B Cell Compartments and Humoral Immunity

  2004influential reference
• Nuclear localization signal and cell synchrony enhance gene targeting efficiency in primary fetal fibroblasts.

  2004cited by this paper
• Interferons, interferon‐like cytokines, and their receptors

  2004influential reference
• Control of smooth muscle development by the myocardin family of transcriptional coactivators.

  2004cited by this paper
• SRF regulates Bcl‐2 expression and promotes cell survival during murine embryonic development

  2004influential reference
• CD19 Function in Early and Late B Cell Development: I. Maintenance of Follicular and Marginal Zone B Cells Requires CD19-Dependent Survival Signals1

  2003cited by this paper
• Novel IL-12 family members shed light on the orchestration of Th1 responses

  2003cited by this paper
• Genetic variations in the interleukin-12/interleukin-23 receptor (β1) chain, and implications for IL-12 and IL-23 receptor structure and function

  2003influential reference
• IL-27 regulates IL-12 responsiveness of naïve CD4+ T cells through Stat1-dependent and -independent mechanisms

  2003cited by this paper
• Serum response factor: toggling between disparate programs of gene expression.

  2003cited by this paper
• Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17*

  2003cited by this paper
• Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF

  2003cited by this paper
• The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses.

  2003cited by this paper
• IFN-gamma bioassay: development of a sensitive method by measuring nitric oxide production by peritoneal exudate cells from C57BL/6 mice.

  2003cited by this paper
• Actin dynamics control SRF activity by regulation of its coactivator MAL.

  2003influential reference
• Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes

  2003cited by this paper
• IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.

  2002cited by this paper
• Activation of the PKB/AKT pathway by ICAM-2.

  2002cited by this paper
• Generation of mice carrying conditional knockout alleles for the transcription factor SRF

  2002influential reference
• Origins and functions of B-1 cells with notes on the role of CD5.

  2002influential reference
• Reduction of marginal zone B cells in CD22‐deficient mice

  2002cited by this paper
• Developmental expression of serum response factor in the rat central nervous system.

  2002cited by this paper
• Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

  2002cited by this paper
• Vav1 Couples T Cell Receptor to Serum Response Factor-dependent Transcription via a MEK-dependent Pathway*

  2002influential reference
• CD19-dependent Activation of Akt Kinase in B-lymphocytes*

  2001cited by this paper
• Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA.

  2001cited by this paper
• Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

  2001cited by this paper
• IL-12p40-Dependent Agonistic Effects on the Development of Protective Innate and Adaptive Immunity Against Salmonella Enteritidis1

  2001cited by this paper
• High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

  2000cited by this paper
• Generation, expansion, migration and activation of mouse B1 cells

  2000cited by this paper
• B‐cell subsets and the mature ­preimmune repertoire. Marginal zone and B1 B cells as part of a “natural immune memory”

  2000cited by this paper
• Granulocyte Colony-stimulating Factor Induces egr-1Up-regulation through Interaction of Serum Response Element-binding Proteins*

  2000cited by this paper
• Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen, Toxoplasma gondii

  2000cited by this paper
• Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

  2000cited by this paper
• Srf−/− ES cells display non‐cell‐autonomous impairment in mesodermal differentiation

  2000cited by this paper
• Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk.

  2000cited by this paper
• Immunity to vaginal herpes simplex virus‐2 infection in B‐cell knockout mice

  2000cited by this paper
• Four isoforms of serum response factor that increase or inhibit smooth-muscle-specific promoter activity.

  2000cited by this paper
• Cytokine Production and Killer Activity of NK/T-NK Cells Derived with IL-2, IL-15, or the Combination of IL-12 and IL-181

  2000influential reference
• An efficient recombination system for chromosome engineering in Escherichia coli.

  2000cited by this paper
• Dominant Negative Murine Serum Response Factor: Alternative Splicing within the Activation Domain Inhibits Transactivation of Serum Response Factor Binding Targets

  1999cited by this paper
• Positive selection of natural autoreactive B cells.

  1999cited by this paper
• Signal-regulated activation of serum response factor is mediated by changes in actin dynamics.

  1999cited by this paper
• Rapid modification of bacterial artificial chromosomes by ET-recombination.

  1999cited by this paper
• The mechanism of phosphorylation‐inducible activation of the ETS‐domain transcription factor Elk‐1

  1999cited by this paper
• Regulation of MCL1 through a Serum Response Factor/Elk-1-mediated Mechanism Links Expression of a Viability-promoting Member of the BCL2 Family to the Induction of Hematopoietic Cell Differentiation*

  1999cited by this paper
• Id helix–loop–helix proteins inhibit nucleoprotein complex formation by the TCF ETS‐domain transcription factors

  1999cited by this paper
• Comparative kinetic analysis of FLP and cre recombinases: mathematical models for DNA binding and recombination.

  1998cited by this paper
• A new logic for DNA engineering using recombination in Escherichia coli

  1998cited by this paper
• Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice.

  1998cited by this paper
• Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation.

  1998cited by this paper
• Improved properties of FLP recombinase evolved by cycling mutagenesis

  1998cited by this paper
• A positive selection vector for cloning of long polymerase chain reaction fragments based on a lethal mutant of the crp gene of Escherichia coli.

  1998cited by this paper
• Cloning and analysis of the promoter region of CXCR4, a coreceptor for HIV-1 entry.

  1997cited by this paper
• B lymphocyte-specific, Cre-mediated mutagenesis in mice.

  1997influential reference
• Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines.

  1997cited by this paper
• CD22 is a negative regulator of B-cell receptor signalling.

  1997cited by this paper
• Interleukin 12 (IL-12) Is Crucial to the Development of Protective Immunity in Mice Intravenously Infected with Mycobacterium tuberculosis

  1997cited by this paper
• Molecular cloning and characterization of murine IL-12 genes.

  1996cited by this paper
• Peptide nucleic acids directed to the promoter of the alpha-chain of the interleukin-2 receptor.

  1996cited by this paper
• Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

  1996cited by this paper
• The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells

  1996cited by this paper
• Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination.

  1996cited by this paper
• Genetically resistant mice lacking interleukin‐12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response

  1996cited by this paper
• A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs.

  1996influential reference
• Self‐renewal of B‐1 lymphocytes is dependent on CD19

  1996cited by this paper
• Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue.

  1996cited by this paper
• IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses.

  1996cited by this paper
• Structure and chromosomal location of the mouse interleukin‐12 p35 and p40 subunit genes

  1996cited by this paper
• Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit.

  1996cited by this paper
• Characterization of murine intercellular adhesion molecule-2.

  1996cited by this paper
• Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells.

  1995cited by this paper
• Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice.

  1995influential reference
• Synergy between signal transduction pathways is obligatory for expression of c-fos in B and T cell lines: implication for c-fos control via surface immunoglobulin and T cell antigen receptors.

  1995cited by this paper
• Interleukin‐12 production by human polymorphonuclear leukocytes

  1995cited by this paper
• Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav

  1995influential reference
• Calcium activates serum response factor-dependent transcription by a Ras- and Elk-1-independent mechanism that involves a Ca2+/calmodulin-dependent kinase

  1995cited by this paper
• Activation of IL-2 receptor alpha-chain gene by individual members of the rel oncogene family in association with serum response factor.

  1995cited by this paper
• The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

  1995cited by this paper
• Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor.

  1995cited by this paper
• Impairment of T-cell-dependent B-cell responses and B-l cell development in CD19-deficient mice

  1995cited by this paper
• Mouse interleukin‐12 (IL‐12) p40 homodimer: a potent IL‐12 antagonist

  1995cited by this paper
• Inducible gene targeting in mice

  1995cited by this paper
• CD2‐CD48 interaction prevents apoptosis in murine B lymphocytes by up‐regulating bcl‐2 expression

  1994cited by this paper
• B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

  1994cited by this paper
• A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2.

  1994cited by this paper
• Homotypic adhesion of rat B cells, but not T cells, in response to cross-linking of CD48.

  1994cited by this paper
• Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells

  1994cited by this paper
• Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein.

  1994cited by this paper
• Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci.

  1994cited by this paper

• Analysis of Infectious Diseases in Conditional Mouse Mutants

  2010cites this paper