The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Neuropharmacology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15275829
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures.

  2004cited by this paper
• Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.

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• The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo.

  2003cited by this paper
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• Retinal Neuron Activity of ETS Domain-binding Sites in a Nicotinic Acetylcholine Receptor Gene Cluster Enhancer*

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• Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.

  2002cited by this paper
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• Potential role of the alpha4 and alpha6 nicotinic receptor subunits in regulating nicotine-induced seizures.

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• Alpha4beta2 Neuronal Nicotinic Acetylcholine Receptors in the Central Nervous System Are Inhibited by Isoflurane and Propofol, but alpha7‐type Nicotinic Acetylcholine Receptors Are Unaffected

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• Assembly of Human Neuronal Nicotinic Receptor α5 Subunits with α3, β2, and β4 Subunits*

  1996cited by this paper
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• Decrease in excitatory transmission within the lateral habenula and the mediodorsal thalamus protects against limbic seizures in rats.

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• Nicotine: Effect on the Sleep Cycle of the Cat

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