Low-density lipoprotein postsecretory modification, monocyte function, and circulating adhesion molecules in type 2 diabetic patients with and without macrovascular complications: the effect of alpha-tocopherol supplementation.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Circulation

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 10889130
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase.

  1999cited by this paper
• GISSI-Prevenzione trial.

  1999cited by this paper
• Lipid peroxidation and atherosclerosis in type II diabetes.

  1999cited by this paper
• High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes.

  1999cited by this paper
• GISSI-Prevenzione trial.

  1999cited by this paper
• alpha-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cells.

  1998cited by this paper
• Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the cholesterol and recurrent events (CARE) trial. The Care Investigators.

  1998cited by this paper
• Susceptibility of LDL to oxidation is not associated with the presence of coronary heart disease or renal dysfunction in NIDDM patients.

  1998cited by this paper
• Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.

  1998cited by this paper
• Troglitazone Reduces LDL Oxidation and Lowers Plasma E-selectin Concentration in NIDDM Patients

  1998cited by this paper
• Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels.

  1998cited by this paper
• Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.

  1998cited by this paper
• Normalization of Plasma Lipid Peroxides, Monocyte Adhesion, and Tumor Necrosis Factor-α Production in NIDDM Patients After Gliclazide Treatment

  1998cited by this paper
• Relationship of Blood Thromboxane-B2 (TxB2) With Lipid Peroxides and Effect of Vitamin E and Placebo Supplementation on TxB2 and Lipid Peroxide Levels in Type 1 Diabetic Patients

  1998cited by this paper
• Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study.

  1998cited by this paper
• Reduction of oxidative stress by oral N-acetyl-L-cysteine treatment decreases plasma soluble vascular cell adhesion molecule-1 concentrations in non-obese, non-dyslipidaemic, normotensive, patients with non-insulin-dependent diabetes

  1998cited by this paper
• Elevated Concentrations of Soluble E-Selectin and Vascular Cell Adhesion Molecule-1 in NIDDM: Effect of intensive insulin treatment

  1998cited by this paper
• Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study.

  1997cited by this paper
• Adherence of Mononuclear Cells to Endothelium In Vitro Is Increased in Patients With NIDDM

  1997cited by this paper
• Cholesterol Lowering With Simvastatin Improves Prognosis of Diabetic Patients With Coronary Heart Disease: A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)

  1997cited by this paper
• Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment.

  1997cited by this paper
• Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

  1996cited by this paper
• Oxidative damage to DNA in diabetes mellitus.

  1996cited by this paper
• Effect of modest vitamin E supplementation on blood glycated hemoglobin and triglyceride levels and red cell indices in type I diabetic patients.

  1996cited by this paper
• Oxidized low-density lipoprotein and atherosclerosis

  1996cited by this paper
• The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators.

  1996cited by this paper
• Hypertriglyceridemia Enhances Monocyte Binding to Endothelial Cells in NIDDM

  1996cited by this paper
• RRR-alpha-tocopheryl acetate supplementation at pharmacologic doses decreases low-density-lipoprotein oxidative susceptibility but not protein glycation in patients with diabetes mellitus.

  1996cited by this paper
• The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium.

  1996cited by this paper
• Vitamin E plus aspirin compared with aspirin alone in patients with transient ischemic attacks.

  1995cited by this paper
• Serum Glycated Lipoproteins in Type II Diabetic Patients with and without Complications

  1995cited by this paper
• Effects of Vitamin E on Susceptibility of Low-Density Lipoprotein and Low-Density Lipoprotein Subfractions to Oxidation and on Protein Glycation in NIDDM

  1995cited by this paper
• Elevated levels of soluble E-selectin in patients with IDDM and NIDDM: relation to metabolic control

  1995cited by this paper
• The effect of alpha-tocopherol supplementation on LDL oxidation. A dose-response study.

  1995cited by this paper
• Increased Levels of Soluble Adhesion Molecules in Type 2 (Non-Insulin Dependent) Diabetes mellitus Are Independent of Glycaemic Control

  1994cited by this paper
• Evidence That Glucose Increases Monocyte Binding to Human Aortic Endothelial Cells

  1994cited by this paper
• Glycation and oxidation: a role in the pathogenesis of atherosclerosis.

  1993cited by this paper
• Daily Vitamin E Supplements Improve Metabolic Control But Not Insulin Secretion in Elderly Type II Diabetic Patients

  1993cited by this paper
• George Lyman Duff Memorial Lecture. Atherogenesis in diabetes.

  1992cited by this paper
• Vitamin E Reduction of Protein Glycosylation in Diabetes: New Prospect for Prevention of Diabetic Complications?

  1991cited by this paper
• Role of oxidized low density lipoprotein in atherogenesis.

  1991cited by this paper
• Agarose gel electrophoresis with nitroblue tetrazolium coloration for determination of glycated lipoproteins in serum from diabetics.

  1990cited by this paper
• Effect of Vitamin E Supplementation on Platelet Thromboxane A2 Production in Type I Diabetic Patients: Double-Blind Crossover Trial

  1988cited by this paper
• Diabetes and atherosclerosis: an epidemiologic view.

  1987cited by this paper
• Superoxide initiates oxidation of low density lipoprotein by human monocytes.

  1987cited by this paper
• Metabolic Activity of Diabetic Monocytes

  1980cited by this paper

• Improvements in markers of inflammation and coagulation potential following a 5-day high-fat diet rich in cottonseed oil vs. Olive oil in healthy males.

  2024cites this paper
• Impact of refining on phytochemicals and anti-inflammatory activity of papaya (Carica papaya L.) seed oil in LPS-stimulated THP-1 cells.

  2024cites this paper
• Bioactive compounds in pomace olive oil modulate the inflammatory response elicited by postprandial triglyceride-rich lipoproteins in BV-2 cells.

  2023cites this paper
• The role of monocytes in thrombotic diseases: a review

  2023cites this paper
• Study of the influence of hyperglycemia on the abundance of amino acids, fatty acids, and selected lipids in extracellular vesicles using TOF-SIMS.

  2022cites this paper
• Leukocyte Counts and T-Cell Frequencies Differ Between Novel Subgroups of Diabetes and Are Associated With Metabolic Parameters and Biomarkers of Inflammation

  2021cites this paper
• Protective Role of Natural and Semi-Synthetic Tocopherols on TNFα-Induced ROS Production and ICAM-1 and Cl-2 Expression in HT29 Intestinal Epithelial Cells

  2021cites this paper
• Association of monocyte-to-high density lipoprotein ratio with arterial stiffness in patients with diabetes

  2021cites this paper
• The effects of twenty-four nutrients and phytonutrients on immune system function and inflammation: A narrative review

  2021cites this paper
• Serum Irisin Levels, Endothelial Dysfunction, and Inflammation in Pediatric Patients with Type 2 Diabetes Mellitus and Metabolic Syndrome

  2020cites this paper
• Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation

  2019cites this paper
• Effects of α-tocopherol on bone marrow mesenchymal cells derived from type II diabetes mellitus rats.

  2018cites this paper
• Update on Vitamin E and Its Potential Role in Preventing or Treating Bronchopulmonary Dysplasia

  2018cites this paper
• High glucose-induced endothelial microparticles increase adhesion molecule expression on endothelial cells

  2018cites this paper
• DIABETES AND PERIODONTAL DISEASES : THE BIDIRECTIONAL ASSOCIATION AND ITS IMPLICATIONS

  2017cites this paper
• Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds.

  2017cites this paper
• Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications.

  2017cites this paper
• Preliminary Report of Inflammatory Markers, Oxidative Stress, and Insulin Resistance in Adolescents of Different Ethnicities

  2016cites this paper
• Monocyte CD163 is altered in association with diabetic complications: possible protective role

  2016cites this paper
• Diabetes propels the risk for cardiovascular disease: sweet monocytes becoming aggressive?

  2016cites this paper
• Progression of Diabetic Capillary Occlusion: A Model

  2016cites this paper
• Local inflammatory reactions in patients with diabetes and periodontitis.

  2015cites this paper
• Serum cytokines and muscle strength after anterior cruciate ligament surgery are not modulated by high-doses of vitamins E (α- and γ-tocopherol's) and C.

  2015cites this paper
• Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis

  2014cites this paper
• Regulation of Inflammatory Phenotype in Macrophages by a Diabetes-Induced Long Noncoding RNA

  2014cites this paper
• Type 2 Diabetes: Endothelial dysfunction and Exercise

  2014cites this paper
• Dysregulation of monocyte biology in metabolic syndrome

  2014cites this paper
• Effects of dietary selenium and vitamin E on immune response and biological blood parameters of broilers reared under thermoneutral or heat stress conditions

  2014cites this paper
• Inflammation, oxidative stress and metabolic syndrome: dietary modulation.

  2014cites this paper
• Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial

  2013cites this paper
• The influence of vitamin E bonded haemodialysis membranes on erythropoiesis stimulating agent requirements, oxidative stress, inflammation, haemostasis and outcomes

  2013cites this paper
• The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome.

  2013cites this paper
• Vitamin E, Its Beneficial Role in Diabetes Mellitus (DM) and Its Complications.

  2012cites this paper
• GSTT1 Null Genotype Is a Risk Factor for Diabetic Retinopathy in Caucasians with Type 2 Diabetes, whereas GSTM1 Null Genotype Might Confer Protection against Retinopathy

  2012cites this paper
• Increased cellular and circulating biomarkers of oxidative stress in nascent metabolic syndrome.

  2012cites this paper
• Vitamin C supplementation reconstitutes polyfunctional T cells in streptozotocin-induced diabetic rats

  2012cites this paper
• Animal Models as Tools to Investigate Antidiabetic and Anti-Inflammatory Plants

  2012cites this paper
• The Effect of Vitamin C and E on Lipid Profile in People with Type 2 Diabetes Mellitus

  2011cites this paper
• Serum interleukin-1 and interleukin-6 are correlated neither with oxidized low density lipoprotein, nor with low-grade inflammation in patients with type 2 diabetes.

  2011cites this paper
• The effects of lipoic acid and α-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial.

  2011cites this paper
• Alternative therapies useful in the management of diabetes: A systematic review

  2011cites this paper
• Effect of orange juice and beverage with phytosterols on cytokines and PAI-1 activity.

  2011cites this paper
• Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta.

  2011cites this paper
• Immune and satellite cells : important role players in muscle recovery after injury

  2011cites this paper
• Role of the Monocyte/Macrophage Cell Lineage in Obesity-Related Insulin Resistance

  2010cites this paper
• Diabetes is a proinflammatory state: a translational perspective

  2010cites this paper
• Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors

  2010cites this paper
• Gender differential in apo E genotypes’ correlative tendency to dyslipidaemia responsiveness upon flaxseed oil administration in adult type 2 diabetic patients not meeting the 2008 Canadian Practice Guidelines

  2010cites this paper
• The true cost of in-patient obesity: impact of obesity on inflammatory stress and morbidity

  2010cites this paper
• [Adhesion molecules and diabetes mellitus].

  2010cites this paper
• Dangers, and benefits of the cytokine mediated response to injury and infection.

  2009cites this paper
• Effect of overweight/obesity on recovery after post-infectious glomerulonephritis.

  2009cites this paper
• Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species.

  2009cites this paper
• No gender associated differences in LDL oxidation in response to a CuSO 4 challenge in a population of Caucasians with well-controlled type 2 diabetes

  2009cites this paper
• [Soluble E- selectin in children and adolescents with type 1 diabetes].

  2008cites this paper
• E-SELECTINA SOLUBLE EN UNA POBLACION INFANTO-JUVENIL CON DIABETES TIPO 1

  2008cites this paper
• Building a knowledge base for systems pathology

  2008cites this paper
• PPARGC1A Variation Associated With DNA Damage, Diabetes, and Cardiovascular Diseases

  2008cites this paper
• Transmembrane signaling pathway mediates oxidized low-density lipoprotein-induced expression of plasminogen activator inhibitor-1 in vascular endothelial cells.

  2008cites this paper
• Serum levels of S100B are decreased in chronic starvation and normalize with weight gain

  2008cites this paper
• Validation of the circulating monocyte being representative of the cholesterol-loaded macrophage: biomediator activity.

  2008cites this paper
• Do Glucose and Lipids Exert Independent Effects on Atherosclerotic Lesion Initiation or Progression to Advanced Plaques?

  2007cites this paper
• Ethnicity and inflammatory pathways - implications for vascular disease, vascular risk and therapeutic intervention.

  2007cites this paper
• Activation of RAGE induces elevated O2− generation by mononuclear phagocytes in diabetes

  2007cites this paper
• Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: an experimental and computational approach.

  2007cites this paper
• Anti-inflammatory properties of aand c-tocopherol

  2007influential citation
• Leukocytes in diabetic retinopathy.

  2007cites this paper
• Evidence of Increased Inflammation and Microcirculatory Abnormalities in Patients With Type 1 Diabetes and Their Role in Microvascular Complications

  2007influential citation
• Alpha-tocopheryl succinate (α-TOS) modulates human prostate LNCaP xenograft growth and gene expression in BALB/c nude mice fed two levels of dietary soybean oil

  2007cites this paper
• Impact of diabetic serum on endothelial cells: an in-vitro-analysis of endothelial dysfunction in diabetes mellitus type 2.

  2007cites this paper
• Anti-inflammatory properties of a- and ?-tocopherol

  2007cites this paper
• Anti-inflammatory properties of alpha- and gamma-tocopherol.

  2007cites this paper
• Effect of high-dose alpha-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease.

  2007cites this paper
• The Use of Vitamin E in Type 2 Diabetes Mellitus

  2007cites this paper
• Monocyte matrix and ADAM metalloproteinase expression in type 2 diabetes after aspirin therapy.

  2006cites this paper
• Effects of colesevelam hydrochloride (WelChol) on biomarkers of inflammation in patients with mild hypercholesterolemia.

  2006cites this paper
• Antioxidant Strategies in Respiratory Medicine

  2006cites this paper
• Effect of vitamin E supplementation with and without hormone therapy on circulatory inflammatory markers in postmenopausal women.

  2006cites this paper
• Effects of dietary factors on oxidation of low-density lipoprotein particles.

  2006cites this paper
• Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes.

  2006cites this paper
• Long-term exposure to oxidized low-density lipoprotein enhances tumor necrosis factor-alpha-stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways.

  2006cites this paper
• Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome.

  2006cites this paper
• Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.

  2006cites this paper
• The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality.

  2006cites this paper
• Sphingosine-1 Phosphate Prevents Monocyte/Endothelial Interactions in Type 1 Diabetic NOD Mice Through Activation of the S1P1 Receptor

  2006cites this paper
• Defining the proinflammatory phenotype using high sensitive C-reactive protein levels as the biomarker.

  2005cites this paper
• The Interaction Between Nutrition and Inflammatory Stress Throughout the Life Cycle

  2005cites this paper
• Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase c-{alpha} and -{beta}.

  2005cites this paper
• Development of an in vitro screening assay to test the antiinflammatory properties of dietary supplements and pharmacologic agents.

  2005cites this paper
• Cardiovascular Disease in Diabetic Nephropathy Patients: Cell Adhesion Molecules as Potential Markers?

  2005cites this paper
• Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis

  2005cites this paper
• Endothelial Dysfunction, Cellular Adhesion Molecules and the Metabolic Syndrome

  2005cites this paper
• Neutrophils are associated with capillary closure in spontaneously diabetic monkey retinas.

  2005influential citation
• Vitamin E, oxidative stress, and inflammation.

  2005cites this paper
• Soluble ICAM-1: a marker of vascular inflammation and lifestyle.

  2005cites this paper
• Vitamin E-Coated Dialyzer Membranes Downregulate Expression of Monocyte Adhesion and Co-Stimulatory Molecules

  2004cites this paper
• Increased soluble E-selectin levels in type 2 diabetic patients with peripheral arterial disease.

  2004cites this paper
• Plasma Insulin Concentration was Increased by Long-Term Ingestion of Guava Juice in Spontaneous Non-Insulin-Dependent Diabetes Mellitus (NIDDM) Rats

  2004cites this paper
• The Role of Antioxidant Micronutrients in the Prevention of Diabetic Complications

  2004cites this paper
• Anti-inflammatory effects of alpha-tocopherol.

  2004cites this paper