The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Rheumatology International

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00270463PMID 3671989
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Suppression of hyaluronic acid synthesis in synovial organ cultures by corticosteroid suspensions.

  1985cited by this paper
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  1985cited by this paper
• Hyaluronic acid production in vitro by synovial lining cells from normal and rheumatoid joints.

  1985cited by this paper
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  1981cited by this paper
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  1980cited by this paper
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  1980cited by this paper
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  1980cited by this paper
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  1979cited by this paper
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  1978cited by this paper
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  1978cited by this paper
• Rheumatoid disease in cultured human synovial cells. A biochemical study on glycosaminoglycans, proteins and plasma membranes of synovial fibroblasts in culture.

  1977influential reference
• Effects of cortisol on glycosaminoglycans synthesized by normal and rheumatoid synovial fibroblasts in vitro.

  1977cited by this paper
• Synthesis of proteoglycans by suspension and monolayer cultures of adult chondrocytes and de novo cartilage nodules-the effect of hyaluronic acid.

  1977cited by this paper
• A simplification of the protein assay method of Lowry et al. which is more generally applicable.

  1977cited by this paper
• Clinical chemistry as a medical disciple.

  1977cited by this paper
• Influence of sulphated glycosaminoglycans upon proteoglycan metabolism of the synovial lining cells.

  1977cited by this paper
• Intra-Articular Treatment of Arthritis in Race-Horses with Sodium Hyaluronate

  1976cited by this paper
• Acid, neutral, and alkaline hydrolases in arthritic synovium.

  1976cited by this paper
• Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture.

  1976cited by this paper
• Human serum and synovial fluid hyaluronidase--bovine testicular hyaluronidase is not a valid substitute in drug evaluation studies.

  1976cited by this paper
• Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

  1976cited by this paper
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  1975cited by this paper
• Connective tissue activation. X. Current studies of the process and its mediators.

  1975cited by this paper
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  1975cited by this paper
• Connective tissue activation. X. Current studies of the process and its mediators.

  1975cited by this paper
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  1974cited by this paper
• Free Radicals and Inflammation: Protection of Synovial Fluid by Superoxide Dismutase

  1974cited by this paper
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  1974cited by this paper
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  1974cited by this paper
• Depression by hyaluronic acid of glycosaminoglycan synthesis by cultured chick embryo chondrocytes.

  1974cited by this paper
• Hyaluronate and Hyaluronidase in Morphogenesis and Differentiation

  1973cited by this paper
• New method for quantitative determination of uronic acids.

  1973cited by this paper
• The inhibition of sulphate incorporation in isolated adult chondrocytes by hyaluronic acid

  1973cited by this paper
• Abnormalities of connective tissue cells cultured from patients with rheumatoid arthritis. II. Defective regulation of hyaluronate and collagen formation.

  1971cited by this paper
• Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of osteoarthritis and on granulation tissue formation.

  1971cited by this paper
• Connective tissue activation. II. Abnormalities of cultured rheumatoid synovial cells.

  1971cited by this paper
• Properties of synovial cells in culture.

  1971cited by this paper
• PROPERTIES OF SYNOVIAL CELLS IN CULTURE

  1971cited by this paper
• Novel hyaluronidase from streptomyces.

  1970cited by this paper
• Hyaluronic acid in synovial fluid. VI. Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of arthritis in track horses.

  1970cited by this paper
• Significance of persistent differences between normal and rheumatoid synovial membrane cells in culture.

  1969cited by this paper
• [105] Determination of DNA concentration with diphenylamine

  1968cited by this paper
• Hyaluronic acid in synovial fluid. I. Molecular parameters of hyaluronic acid in normal and arthritis human fluids.

  1967cited by this paper
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  1966cited by this paper
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  1966cited by this paper
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  1966cited by this paper
• Function of specific bile acids in cholesterol esterase activity in vitro.

  1965cited by this paper
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